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Coexpression cluster:C4154: Difference between revisions

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|full_id=C4154_CD4_CD8_Natural_CD34_CD14_Basophils_Peripheral
|full_id=C4154_CD4_CD8_Natural_CD34_CD14_Basophils_Peripheral
|id=C4154
|id=C4154
|ontology_enrichment_celltype=CL:0000791!3.90e-29!18;CL:0000789!3.90e-29!18;CL:0002420!3.90e-29!18;CL:0002419!3.90e-29!18;CL:0000790!3.90e-29!18;CL:0000738!2.44e-26!140;CL:0000084!1.64e-21!25;CL:0000827!1.64e-21!25;CL:0000625!6.63e-21!11;CL:0000037!3.30e-19!172;CL:0000566!3.30e-19!172;CL:0000988!4.50e-18!182;CL:0002087!1.17e-17!119;CL:0002031!3.11e-17!124;CL:0002032!7.38e-17!165;CL:0000837!7.38e-17!165;CL:0000838!5.91e-16!52;CL:0000542!1.67e-15!53;CL:0000051!1.67e-15!53;CL:0000624!6.57e-12!6;CL:0000766!8.57e-08!76;CL:0000094!1.23e-07!8;CL:0002057!2.18e-07!42;CL:0000081!5.75e-07!11;CL:0000898!9.02e-07!3
|ontology_enrichment_celltype=CL:0000791!8.99e-59!18;CL:0000789!8.99e-59!18;CL:0002420!8.99e-59!18;CL:0002419!8.99e-59!18;CL:0000790!8.99e-59!18;CL:0000625!4.12e-41!11;CL:0000084!4.70e-41!25;CL:0000827!4.70e-41!25;CL:0000838!6.34e-30!52;CL:0000542!3.00e-29!53;CL:0000051!3.00e-29!53;CL:0002242!5.64e-28!55;CL:0000624!7.14e-23!6;CL:0000738!1.80e-21!136;CL:0002087!2.57e-18!115;CL:0000037!4.21e-17!168;CL:0000566!4.21e-17!168;CL:0000988!8.07e-16!177;CL:0002031!8.43e-16!120;CL:0002032!1.92e-14!161;CL:0000837!1.92e-14!161;CL:0000898!3.33e-12!3;CL:0000623!8.73e-12!3;CL:0000825!8.73e-12!3;CL:0000767!1.75e-11!3;CL:0000815!1.74e-08!2;CL:0000792!1.74e-08!2;CL:0002677!1.74e-08!2;CL:0000094!2.21e-07!8
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!8.28e-13!102;UBERON:0003061!8.28e-13!102;UBERON:0000178!5.41e-12!15;UBERON:0000179!5.41e-12!15;UBERON:0000463!5.41e-12!15;UBERON:0002193!1.48e-11!112
|ontology_enrichment_uberon=UBERON:0002370!1.43e-08!4;UBERON:0005058!1.43e-08!4;UBERON:0009113!1.43e-08!4;UBERON:0003295!1.43e-08!4;UBERON:0005562!1.43e-08!4;UBERON:0000178!4.64e-08!15;UBERON:0000179!4.64e-08!15;UBERON:0000463!4.64e-08!15
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973,0.211746,0.220538,0.0801488,0.0757897,0.161801,0.193215,0.0549034,0.0779715,0.0561838,0.0417636,0.0345419,0.0388736,0.254674,0.170307,0.201033,0.0488949,0.174921,0.370421,0.0330727,0.348757,0.219556,0.0394698,0.0596469,0.419264,0.122476,0.108872,0.11002,0.26144,0.0286025,0.549354,0.144567,0.038848,0.0874516,0.0550279,0.144067,0.253693,0.217069,0.190048,0.131088,0.394069,0.237101,0.286988,0.0761239,0.172491,0.0818785,0.182701,0.335058,0.147698,0.141463,0.167267,0.140622,0.0889592,0.309588,0.28711,0.0473033,0.094881,0.445524,0.132886,0.0774373,0.109194,0.128564,0.131452,0.687347,0.448776,0.051838,0.0993999,0.0500365,0.061829,0.0755121,0.0936516,0.144075,0.0340203,0.0741807,0.277091,0.739716,0.655293,0.21727,0.289306,0.119215,0.192475,0.177967,0.547859,0.057571,0.047591,0.392974,0.0608699,0.175319,0.300597,0.0713214,0.223874,0.291114,0.0355833,0.125606,0.175094,0.911304,0.936279,0.206454,0.218192,0.108277,0.0673484,0.108748,0.0494066,0.0958493,0.205732,0.0755808,0.045654,0.110216,0.070276,0.226171,0.153469,0.0376916,0.13262,0.0450031,0.0539144,0.114242,0.0929549,0.172425,0.104948,0.221645,0.057168,0.234298,0.0759837,0.286863,0.152372,0.194941,0.218271,0.101607,0.327067,0.172982,0.340936,0.151597,0.0626744,0.191335,0.148574,0.504592,0.155821,0.0718905,0.0919008,0.0602373,0.144304,0.15063,0.0973823,0.15503,0.170295,0.193653,0.137219,0.228144,0.251466,0.288096,0.11903,0.0838874,0.331451,0.113145,0.112651,0.186638,0.174776,0.0948451,0.264079,0.249049,0.140533,0.0997756,0.257598,0.103667,0.113069,0.025556,0.16791,0.09066,0.585505,0.166967,0.188651,0.0813902,0.184948,0.156261,0.311847,0.511859,0.0590944,0.247324,0.178389,0.218229,0.231073,0.407281,0.619906,0.0360851,0.412187,0.131093,0.0434602,0.133616,0.418146,0.36927,0.449036,0.407369,0.231447,0.544776,0.43956,0.0116789,0.42622,0.448797,0.197484,0.396996,0.36145,0.406019,0.381071,0.580441,0.643768,0.432035,0.722159,0.390366,0.48809,0.50058,0.443185,0.522904,0.875915,0.871256,0.227104,0.518585,0.617852,0.38649,0.284625,0.504757,0.55194,0.729153,0.28907,0.164197,0.462688,0.287881,0.574635,0.478174,0.336276,0.468444,0.258219,0.446557,0.243383,0.777351,0.390974,0.73485,0.683217,0.161598,0.751174,0.644754,0.496032,0.799185,0.37357,0.78509,0.477353,0.78384,0.746954,0.771991,0.20342,0.200493,0.20558,0.300504,0.25656,0.425963,0.349197,0.383291,0.156104,0.141318,0.411941,0.0961477,0.314438,0.354789,0.0142192,0.230581,0.120226,0.28424,0.562405,0.314429,0.181415,0.282286,0.78,0.616388,0.408413,0.516511,0.322213,0.656109,0.33942,0.61031,0.387276,0.522605,0.802166,0.537348,0.222037,0.102227,0.416292,0.462712,0.734551,0.579431,0.204817,0.452428,0.138871,0.673493,0.166905,0.19783,0.0833851,0.316453,0.48065,0.175199,0.332919,0.373557,0.523625,0.408861,0.365487,0.534741,0.39088,0.363192,0.236011,0.203486,0.273398,0.375787,0.4466,0.351067,0.275347,0.637444,0.305885,0.241132,0.371414,0.30666,0.303709,0.495883,0.386538,0.508064,0.250964,0.0851927,0.457886,0.504711,0.220231,0.509064,0.196976,0.191517,0.129584,0.601877,0.307334,0.459728,0.044623,0.563586,0.472935,0.399569,0.273281,0.368095,0.275089,0.384593,0.138622,0.359231,0.339729,0.197805,0.608187,0.387069,0.332774,0.52832,0.299887,0.634365,0.205413,0.17639,0.0779009,0.276869,0.205298,0.0337138,0.18966,0.258854,0.188263,0.0719199,0.264884,0.162568,0.19104,0.163057,0.219428,0.0233135,0.0900729,0.0953646,0.166124,0.252184,0.378361,0.255516,0.20753,0.447185,0.179412,0.193601,0.220904,0.222977,0.341681,0.310674,0.21801,0.198614,0.186804,0.123324,0.199468,0.0325925,0.0933115,0.12405,0.179889,0.226869,0.27872,0.0855609,0.131118,0.20837,0.247588,0.222339,0.0673329,0.20847,0.266544,0.113092,0.145701,0.229428,0.162145,0.228955,0.168748,0.0384949,0.0660995,0.0521984,0.0455518,0.268741,0.201602,0.350452,0.154941,0.120196,0.0986735,0.108462,0.0595618,0.21593,0.158479,0.220319,0.195218,0.124213,0.259632,0.30793,0.180606,0.159884,0.257294,0.150733,0.217112,0.123917,0.184317,0.185335,0.0723291,0.258496,0.261744,0.203781,0.21382,0.207559,0.141867,0.193031,0.249101,0.115972,0.224568,0.246105,0.173026,0.200432,0.139785,0.197112,0.240478,0.156465,0.13108,0.256963,0.222798,0.172134,0.176789,0.0969345,0.202137,0.310405,0.280943,0.0257454,0.0822373,0.202065,0.106739,0.0536053,0.0537737,0.15113,0.078016,0.0407233,0.0537355,0.319922,0.261724,0.0240944,0.187731,0.233626,0.189559,0.0812887,0.0981146,0.064145,0.121913,0.0638699,0.104603,0.0663259,0.0762523,0.128736,0.109171,0.04411,0.066952,0.089609,0.0367455,0.13497,0.204393,0.295769,0.286691,0.347036,0.141729,0.263159,0.255956,0.200105,0.227491,0.29837,0.253509,0.177664,0.28365,0.264413,0.131761,0.160658,0.206239,0.19924,0.28689,0.236464,0.325148,0.115817,0.218052,0.223831,0.11528,0.194982,0.190993,0.281727,0.283218,0.249955,0.164638,0.224257,0.0935776,0.327622,0.225752,0.207791,0.0958756,0.0859274,0.316866,0.171683,0.158847,0.271275,0.071111,0.270604,0.101021,0.222548,0.175934,0.157274,0.215705,0.252796,0.205954,0.361435
}}
}}

Revision as of 15:43, 19 October 2012


Full id: C4154_CD4_CD8_Natural_CD34_CD14_Basophils_Peripheral



Phase1 CAGE Peaks

Hg19::chr2:181978727..181978730,+p@chr2:181978727..181978730
+
Hg19::chr5:35857380..35857384,+p@chr5:35857380..35857384
+
Hg19::chr5:35859622..35859626,+p@chr5:35859622..35859626
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
mature alpha-beta T cell8.99e-5918
alpha-beta T cell8.99e-5918
immature T cell8.99e-5918
mature T cell8.99e-5918
immature alpha-beta T cell8.99e-5918
CD8-positive, alpha-beta T cell4.12e-4111
T cell4.70e-4125
pro-T cell4.70e-4125
lymphoid lineage restricted progenitor cell6.34e-3052
lymphocyte3.00e-2953
common lymphoid progenitor3.00e-2953
nucleate cell5.64e-2855
CD4-positive, alpha-beta T cell7.14e-236
leukocyte1.80e-21136
nongranular leukocyte2.57e-18115
hematopoietic stem cell4.21e-17168
angioblastic mesenchymal cell4.21e-17168
hematopoietic cell8.07e-16177
hematopoietic lineage restricted progenitor cell8.43e-16120
hematopoietic oligopotent progenitor cell1.92e-14161
hematopoietic multipotent progenitor cell1.92e-14161
naive T cell3.33e-123
natural killer cell8.73e-123
pro-NK cell8.73e-123
basophil1.75e-113
regulatory T cell1.74e-082
CD4-positive, CD25-positive, alpha-beta regulatory T cell1.74e-082
naive regulatory T cell1.74e-082
granulocyte2.21e-078
Uber Anatomy
Ontology termp-valuen
thymus1.43e-084
hemolymphoid system gland1.43e-084
thymic region1.43e-084
pharyngeal gland1.43e-084
thymus primordium1.43e-084
blood4.64e-0815
haemolymphatic fluid4.64e-0815
organism substance4.64e-0815


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.