MCL coexpression mm9:475

Phase1 CAGE Peaks

	Short description
Mm9::chr10:126627037..126627127,-	p1@Arhgef25
Mm9::chr12:87419853..87419891,-	p1@Tgfb3
Mm9::chr16:17797310..17797321,+	p2@Scarf2
Mm9::chr1:45368469..45368483,+	p1@Col3a1
Mm9::chr1:45378434..45378486,+	p@chr1:45378434..45378486 +
Mm9::chr1:45394139..45394159,+	p@chr1:45394139..45394159 +
Mm9::chr1:45394262..45394284,+	p@chr1:45394262..45394284 +
Mm9::chr1:45458939..45458951,+	p@chr1:45458939..45458951 +
Mm9::chr2:27741904..27741915,+	p4@Col5a1
Mm9::chr2:27741936..27741960,+	p3@Col5a1
Mm9::chr2:27741964..27741981,+	p1@Col5a1
Mm9::chr2:27741999..27742013,+	p2@Col5a1
Mm9::chr2:84888644..84888660,+	p@chr2:84888644..84888660 +
Mm9::chr8:107779000..107779057,-	p1@B3gnt9-ps
Mm9::chrX:9694723..9694803,-	p1@Srpx

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0030020	extracellular matrix structural constituent conferring tensile strength	0.00121006827987927
GO:0005581	collagen	0.00121006827987927
GO:0005201	extracellular matrix structural constituent	0.00224040548834851
GO:0006817	phosphate transport	0.00224040548834851
GO:0044420	extracellular matrix part	0.0033840341444891
GO:0015698	inorganic anion transport	0.00620766434194275
GO:0044421	extracellular region part	0.00620766434194275
GO:0006820	anion transport	0.00620766434194275
GO:0005588	collagen type V	0.00620766434194275
GO:0005583	fibrillar collagen	0.00744838094941756
GO:0005160	transforming growth factor beta receptor binding	0.010154657312649
GO:0005578	proteinaceous extracellular matrix	0.0127967149823794
GO:0030879	mammary gland development	0.0314502842176471
GO:0022610	biological adhesion	0.0440224212608831
GO:0007155	cell adhesion	0.0440224212608831
GO:0005615	extracellular space	0.0451027695374246

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
tissue	3.42e-07	349

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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