MCL coexpression mm9:1020

Phase1 CAGE Peaks

	Short description
Mm9::chr10:30698559..30698561,-	p@chr10:30698559..30698561 -
Mm9::chr11:110813223..110813228,-	p@chr11:110813223..110813228 -
Mm9::chr11:11954302..11954310,-	p1@ENSMUST00000082868
Mm9::chr12:55340225..55340232,+	p1@ENSMUST00000082671
Mm9::chr13:96667070..96667075,-	p1@ENSMUST00000083932
Mm9::chr3:65892179..65892181,-	p1@ENSMUST00000082588
Mm9::chr5:34873297..34873300,+	p1@ENSMUST00000157707

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

no results for this coexpression

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

---

Cell Type

Ontology term	p-value	n
animal cell	8.05e-39	115
eukaryotic cell	8.05e-39	115
somatic cell	3.07e-37	118
stem cell	4.24e-36	97
somatic stem cell	8.60e-35	91
multi fate stem cell	8.60e-35	91
neural cell	1.87e-33	43
non-terminally differentiated cell	5.54e-33	49
ectodermal cell	2.32e-32	44
neurectodermal cell	2.32e-32	44
embryonic cell	3.32e-29	70
neuron	8.82e-27	33
neuronal stem cell	8.82e-27	33
neuroblast	8.82e-27	33
electrically signaling cell	8.82e-27	33
electrically responsive cell	3.96e-26	39
electrically active cell	3.96e-26	39
CNS neuron (sensu Vertebrata)	4.91e-22	23
neuroblast (sensu Vertebrata)	4.91e-22	23
motile cell	3.28e-16	54
connective tissue cell	4.75e-12	46
mesenchymal cell	4.75e-12	46
hematopoietic lineage restricted progenitor cell	2.09e-08	25
oligodendrocyte precursor cell	3.89e-08	8
myeloid lineage restricted progenitor cell	8.94e-08	13
migratory neural crest cell	2.62e-07	10
neuron associated cell	2.62e-07	10
glial cell (sensu Vertebrata)	2.62e-07	10
neuron associated cell (sensu Vertebrata)	2.62e-07	10
glial cell	2.62e-07	10
glioblast	2.62e-07	10
glioblast (sensu Vertebrata)	2.62e-07	10
autonomic neuron	4.87e-07	9
neuron of cerebral cortex	6.41e-07	6

Uber Anatomy

Ontology term	p-value	n
central nervous system	6.74e-26	73
nervous system	9.01e-26	75
gray matter	5.39e-22	34
brain grey matter	1.78e-17	29
regional part of telencephalon	1.78e-17	29
telencephalon	1.78e-17	29
ectoderm-derived structure	8.17e-17	95
ectoderm	8.17e-17	95
presumptive ectoderm	8.17e-17	95
regional part of nervous system	1.40e-15	54
cerebral cortex	4.05e-14	21
cerebral hemisphere	4.05e-14	21
pallium	4.05e-14	21
neural tube	4.74e-13	52
neural rod	4.74e-13	52
future spinal cord	4.74e-13	52
neural keel	4.74e-13	52
regional part of cerebral cortex	1.25e-12	17
connective tissue	4.75e-12	46
neurectoderm	3.13e-11	64
neural plate	3.13e-11	64
presumptive neural plate	3.13e-11	64
regional part of forebrain	6.94e-11	39
forebrain	6.94e-11	39
future forebrain	6.94e-11	39
anterior neural tube	2.03e-10	40
occipital lobe	2.70e-10	10
visual cortex	2.70e-10	10
neocortex	2.70e-10	10
regional part of brain	5.44e-10	46
brain	1.33e-09	47
future brain	1.33e-09	47
ecto-epithelium	1.44e-08	73
organ system subdivision	3.13e-07	194
pre-chordal neural plate	3.78e-07	49
autonomic nervous system	4.87e-07	9
bone marrow	6.75e-07	16

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}