Novel motif:54

name:	motif54_CGNGTA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0097039	protein linear polyubiquitination	2.276605e-10
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	2.442369e-10
GO:0007549	dosage compensation	3.689938e-10
GO:0071569	protein ufmylation	4.247101e-9
GO:0071109	superior temporal gyrus development	9.290911e-9
GO:0006449	regulation of translational termination	1.351161e-8
GO:0016032	viral reproduction	4.875663e-8
GO:0006366	transcription from RNA polymerase II promoter	1.092928e-7
GO:0060466	activation of meiosis involved in egg activation	1.448090e-7
GO:0043503	skeletal muscle fiber adaptation	2.679839e-7
GO:0006414	translational elongation	3.005027e-7
GO:0006412	translation	4.509964e-7
GO:0006353	transcription termination, DNA-dependent	4.935390e-7
GO:0022415	viral reproductive process	5.640507e-7
GO:0048790	maintenance of presynaptic active zone structure	6.556311e-7
GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane	6.556311e-7
GO:0042026	protein refolding	7.244737e-7
GO:0000422	mitochondrion degradation	8.930957e-7
GO:0051001	negative regulation of nitric-oxide synthase activity	1.374165e-6
GO:0045905	positive regulation of translational termination	1.503845e-6
GO:0045901	positive regulation of translational elongation	1.503845e-6
GO:0006452	translational frameshifting	1.503845e-6
GO:0046479	glycosphingolipid catabolic process	1.630907e-6
GO:0033342	negative regulation of collagen binding	1.654966e-6
GO:0051028	mRNA transport	1.955572e-6
GO:0006415	translational termination	2.081307e-6
GO:0019083	viral transcription	2.810255e-6
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	3.293488e-6
GO:0072126	positive regulation of glomerular mesangial cell proliferation	4.927357e-6
GO:0071506	cellular response to mycophenolic acid	4.927357e-6
GO:0008612	peptidyl-lysine modification to hypusine	5.257800e-6
GO:0061003	positive regulation of dendritic spine morphogenesis	5.257800e-6
GO:0006448	regulation of translational elongation	6.818988e-6
GO:0010506	regulation of autophagy	7.161687e-6
GO:0034660	ncRNA metabolic process	8.351862e-6
GO:0006285	base-excision repair, AP site formation	9.144132e-6
GO:0006352	transcription initiation, DNA-dependent	1.073192e-5
GO:0015887	pantothenate transmembrane transport	1.145539e-5
GO:0015878	biotin transport	1.145539e-5
GO:0072303	positive regulation of glomerular metanephric mesangial cell proliferation	1.217982e-5
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1.227447e-5
GO:0072109	glomerular mesangium development	1.295742e-5
GO:0001710	mesodermal cell fate commitment	1.448850e-5
GO:0031619	homologous chromosome orientation involved in meiotic metaphase I plate congression	1.449657e-5
GO:0008049	male courtship behavior	1.449657e-5
GO:0043241	protein complex disassembly	1.497764e-5
GO:0043624	cellular protein complex disassembly	1.588960e-5
GO:0007029	endoplasmic reticulum organization	1.610780e-5
GO:0052697	xenobiotic glucuronidation	1.624288e-5
GO:0070980	biphenyl catabolic process	1.624288e-5
GO:0052696	flavonoid glucuronidation	1.624288e-5
GO:0051552	flavone metabolic process	1.624288e-5
GO:0006789	bilirubin conjugation	1.624288e-5
GO:0019058	viral infectious cycle	1.791591e-5
GO:0015074	DNA integration	1.868312e-5
GO:0045090	retroviral genome replication	1.930771e-5
GO:0008535	respiratory chain complex IV assembly	1.968778e-5
GO:0000002	mitochondrial genome maintenance	1.984788e-5
GO:0022614	membrane to membrane docking	2.225507e-5
GO:0006313	transposition, DNA-mediated	2.440756e-5
GO:0008625	induction of apoptosis via death domain receptors	2.847547e-5
GO:0010999	regulation of eIF2 alpha phosphorylation by heme	3.083079e-5
GO:0035621	ER to Golgi ceramide transport	3.083079e-5
GO:0009098	leucine biosynthetic process	3.083079e-5
GO:0009589	detection of UV	3.083079e-5
GO:0006550	isoleucine catabolic process	3.083079e-5
GO:0006348	chromatin silencing at telomere	3.112043e-5
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	3.256172e-5
GO:0018364	peptidyl-glutamine methylation	3.673747e-5
GO:0035284	brain segmentation	4.528223e-5
GO:0014051	gamma-aminobutyric acid secretion	4.543062e-5
GO:0072110	glomerular mesangial cell proliferation	5.025938e-5
GO:0045163	clustering of voltage-gated potassium channels	5.025938e-5
GO:0034470	ncRNA processing	5.029255e-5
GO:0046785	microtubule polymerization	5.348731e-5
GO:0060179	male mating behavior	5.876979e-5
GO:0010509	polyamine homeostasis	6.088042e-5
GO:2000111	positive regulation of macrophage apoptosis	7.807256e-5
GO:0032581	ER-dependent peroxisome organization	7.856001e-5
GO:0030149	sphingolipid catabolic process	8.030052e-5
GO:0001696	gastric acid secretion	8.203885e-5
GO:0070389	chaperone cofactor-dependent protein refolding	9.410994e-5
GO:0015812	gamma-aminobutyric acid transport	9.964965e-5
GO:0006354	transcription elongation, DNA-dependent	1.113886e-4
GO:0019377	glycolipid catabolic process	1.138363e-4
GO:2000725	regulation of cardiac muscle cell differentiation	1.144217e-4
GO:0070857	regulation of bile acid biosynthetic process	1.173491e-4
GO:0009294	DNA mediated transformation	1.294104e-4
GO:0014733	regulation of skeletal muscle adaptation	1.298533e-4
GO:0019086	late viral mRNA transcription	1.298533e-4
GO:0007343	egg activation	1.393169e-4
GO:0035445	borate transmembrane transport	1.428100e-4
GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system	1.428100e-4
GO:0048703	embryonic viscerocranium morphogenesis	1.453247e-4
GO:0042373	vitamin K metabolic process	1.457928e-4
GO:0046477	glycosylceramide catabolic process	1.462099e-4
GO:0009804	coumarin metabolic process	1.504419e-4
GO:0072124	regulation of glomerular mesangial cell proliferation	1.621039e-4
GO:0050658	RNA transport	1.624425e-4
GO:0021658	rhombomere 3 morphogenesis	1.655492e-4
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.656944e-4
GO:0046466	membrane lipid catabolic process	1.772186e-4
GO:0045008	depyrimidination	1.779271e-4
GO:0046784	intronless viral mRNA export from host nucleus	1.845655e-4
GO:0006297	nucleotide-excision repair, DNA gap filling	1.878474e-4
GO:0071385	cellular response to glucocorticoid stimulus	1.887095e-4
GO:0007181	transforming growth factor beta receptor complex assembly	1.963056e-4
GO:2000109	regulation of macrophage apoptosis	2.335874e-4
GO:0046521	sphingoid catabolic process	2.618489e-4
GO:0006360	transcription from RNA polymerase I promoter	2.711096e-4
GO:0006403	RNA localization	2.735773e-4
GO:0016188	synaptic vesicle maturation	2.785849e-4
GO:0031109	microtubule polymerization or depolymerization	3.087284e-4
GO:0006499	N-terminal protein myristoylation	3.182518e-4
GO:0007619	courtship behavior	3.243732e-4
GO:0045143	homologous chromosome segregation	3.243732e-4
GO:0006361	transcription initiation from RNA polymerase I promoter	3.487882e-4
GO:0055005	ventricular cardiac myofibril development	3.625593e-4
GO:0006406	mRNA export from nucleus	3.668247e-4
GO:0097045	phosphatidylserine exposure on blood platelet	4.241284e-4
GO:0072301	regulation of metanephric glomerular mesangial cell proliferation	4.280556e-4
GO:0016139	glycoside catabolic process	4.441111e-4
GO:0042254	ribosome biogenesis	4.489674e-4
GO:0007635	chemosensory behavior	4.972158e-4
GO:0060431	primary lung bud formation	5.549837e-4
GO:0072134	nephrogenic mesenchyme morphogenesis	5.865138e-4
GO:0071480	cellular response to gamma radiation	5.992302e-4
GO:0009107	lipoate biosynthetic process	6.289620e-4
GO:0070498	interleukin-1-mediated signaling pathway	6.409351e-4
GO:0060580	ventral spinal cord interneuron fate determination	6.532905e-4
GO:0003327	type B pancreatic cell fate commitment	6.532905e-4
GO:0032915	positive regulation of transforming growth factor beta2 production	6.552439e-4
GO:0032984	macromolecular complex disassembly	6.865925e-4
GO:0016180	snRNA processing	7.003810e-4
GO:0043501	skeletal muscle adaptation	7.192102e-4
GO:0034162	toll-like receptor 9 signaling pathway	7.362497e-4
GO:0033979	box H/ACA snoRNA metabolic process	7.362497e-4
GO:0071157	negative regulation of cell cycle arrest	7.412176e-4
GO:0051320	S phase	7.575380e-4
GO:0034623	cellular macromolecular complex disassembly	7.599712e-4
GO:0050975	sensory perception of touch	7.796036e-4
GO:0000236	mitotic prometaphase	7.938679e-4
GO:0046601	positive regulation of centriole replication	8.171175e-4
GO:0051089	constitutive protein ectodomain proteolysis	8.171175e-4
GO:0043308	eosinophil degranulation	8.171175e-4
GO:0044342	type B pancreatic cell proliferation	8.531917e-4
GO:0010918	positive regulation of mitochondrial membrane potential	8.531917e-4
GO:0033692	cellular polysaccharide biosynthetic process	8.881658e-4
GO:0030433	ER-associated protein catabolic process	9.249217e-4
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	9.478473e-4
GO:0010983	positive regulation of high-density lipoprotein particle clearance	9.691193e-4
GO:0009386	translational attenuation	9.691193e-4
GO:0000718	nucleotide-excision repair, DNA damage removal	9.768071e-4
GO:0033233	regulation of protein sumoylation	9.984014e-4
GO:0046514	ceramide catabolic process	1.000858e-3
GO:2000987	positive regulation of behavioral fear response	1.009604e-3
GO:2000727	positive regulation of cardiac muscle cell differentiation	1.009604e-3
GO:0003185	sinoatrial valve morphogenesis	1.009604e-3
GO:0003138	primary heart field specification	1.009604e-3
GO:0035984	cellular response to trichostatin A	1.009604e-3
GO:0010988	regulation of low-density lipoprotein particle clearance	1.020690e-3
GO:0000715	nucleotide-excision repair, DNA damage recognition	1.020690e-3
GO:0006369	termination of RNA polymerase II transcription	1.039047e-3
GO:0080154	regulation of fertilization	1.058302e-3
GO:2000438	negative regulation of monocyte extravasation	1.058302e-3
GO:0035724	CD24 biosynthetic process	1.058302e-3
GO:0035723	interleukin-15-mediated signaling pathway	1.058302e-3
GO:0002003	angiotensin maturation	1.058302e-3
GO:0033057	multicellular organismal reproductive behavior	1.084488e-3
GO:0042398	cellular modified amino acid biosynthetic process	1.096715e-3
GO:0000028	ribosomal small subunit assembly	1.108290e-3
GO:0006363	termination of RNA polymerase I transcription	1.130338e-3
GO:0090192	regulation of glomerulus development	1.202981e-3
GO:0060264	regulation of respiratory burst involved in inflammatory response	1.211381e-3
GO:0071205	protein localization to juxtaparanode region of axon	1.230418e-3
GO:0015816	glycine transport	1.254906e-3
GO:2000252	negative regulation of feeding behavior	1.262401e-3
GO:0006433	prolyl-tRNA aminoacylation	1.262401e-3
GO:0006768	biotin metabolic process	1.317121e-3
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	1.358069e-3
GO:0071312	cellular response to alkaloid	1.372175e-3
GO:0070086	ubiquitin-dependent endocytosis	1.382274e-3
GO:0072298	regulation of metanephric glomerulus development	1.416767e-3
GO:0070327	thyroid hormone transport	1.424188e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.481179e-3
GO:0019585	glucuronate metabolic process	1.481488e-3
GO:0090150	establishment of protein localization in membrane	1.543480e-3
GO:0000114	regulation of transcription involved in G1 phase of mitotic cell cycle	1.581756e-3
GO:0035461	vitamin transmembrane transport	1.637985e-3
GO:0070858	negative regulation of bile acid biosynthetic process	1.637985e-3
GO:0072111	cell proliferation involved in kidney development	1.639522e-3
GO:0060263	regulation of respiratory burst	1.646487e-3
GO:0000956	nuclear-transcribed mRNA catabolic process	1.658558e-3
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	1.767553e-3
GO:0090073	positive regulation of protein homodimerization activity	1.831485e-3
GO:0000920	cytokinetic cell separation	1.886055e-3
GO:0015866	ADP transport	1.911984e-3
GO:0021666	rhombomere 5 formation	1.911984e-3
GO:0030327	prenylated protein catabolic process	1.911984e-3
GO:0021660	rhombomere 3 formation	1.911984e-3
GO:0061001	regulation of dendritic spine morphogenesis	1.931446e-3
GO:0009264	deoxyribonucleotide catabolic process	1.963762e-3
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	1.977818e-3
GO:0016073	snRNA metabolic process	1.994019e-3
GO:0007000	nucleolus organization	2.007542e-3
GO:0000216	M/G1 transition of mitotic cell cycle	2.097644e-3
GO:0006298	mismatch repair	2.234693e-3
GO:0048343	paraxial mesodermal cell fate commitment	2.236255e-3
GO:0032042	mitochondrial DNA metabolic process	2.249108e-3
GO:0030644	cellular chloride ion homeostasis	2.249108e-3
GO:0060025	regulation of synaptic activity	2.358005e-3
GO:0006677	glycosylceramide metabolic process	2.395132e-3
GO:0006289	nucleotide-excision repair	2.554169e-3
GO:0071398	cellular response to fatty acid	2.555455e-3
GO:2001016	positive regulation of skeletal muscle cell differentiation	2.578978e-3
GO:0072133	metanephric mesenchyme morphogenesis	2.611077e-3
GO:0010498	proteasomal protein catabolic process	2.624991e-3
GO:0043966	histone H3 acetylation	2.661552e-3
GO:0006626	protein targeting to mitochondrion	2.713931e-3
GO:0000723	telomere maintenance	2.721293e-3
GO:0071504	cellular response to heparin	2.754213e-3
GO:0006401	RNA catabolic process	2.772658e-3
GO:0010984	regulation of lipoprotein particle clearance	2.779999e-3
GO:0046398	UDP-glucuronate metabolic process	2.779999e-3
GO:0019048	virus-host interaction	2.892490e-3
GO:0031442	positive regulation of mRNA 3'-end processing	2.978742e-3
GO:0003061	positive regulation of the force of heart contraction by norepinephrine	3.001121e-3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	3.001121e-3
GO:0032864	activation of Cdc42 GTPase activity	3.004807e-3
GO:2000077	negative regulation of type B pancreatic cell development	3.012562e-3
GO:0018277	protein deamination	3.012562e-3
GO:0007098	centrosome cycle	3.044062e-3
GO:0034661	ncRNA catabolic process	3.070158e-3
GO:0031572	G2/M transition DNA damage checkpoint	3.217974e-3
GO:0008645	hexose transport	3.291582e-3
GO:0016137	glycoside metabolic process	3.337052e-3
GO:2000074	regulation of type B pancreatic cell development	3.343551e-3
GO:0015931	nucleobase-containing compound transport	3.377639e-3
GO:0019264	glycine biosynthetic process from serine	3.443875e-3
GO:0015749	monosaccharide transport	3.547081e-3
GO:0014745	negative regulation of muscle adaptation	3.563720e-3
GO:0046501	protoporphyrinogen IX metabolic process	3.595701e-3
GO:0006367	transcription initiation from RNA polymerase II promoter	3.643371e-3
GO:0043084	penile erection	3.647950e-3
GO:0033566	gamma-tubulin complex localization	3.720344e-3
GO:2000009	negative regulation of protein localization at cell surface	3.729022e-3
GO:0015761	mannose transport	3.729022e-3
GO:0006268	DNA unwinding involved in replication	3.812519e-3
GO:0051354	negative regulation of oxidoreductase activity	3.821861e-3
GO:0032727	positive regulation of interferon-alpha production	3.943448e-3
GO:0006244	pyrimidine nucleotide catabolic process	3.973322e-3
GO:0006600	creatine metabolic process	3.974731e-3
GO:0071503	response to heparin	4.034086e-3
GO:0051182	coenzyme transport	4.164070e-3
GO:0015959	diadenosine polyphosphate metabolic process	4.167926e-3
GO:0006479	protein methylation	4.183554e-3
GO:0019883	antigen processing and presentation of endogenous antigen	4.240633e-3
GO:0010826	negative regulation of centrosome duplication	4.289618e-3
GO:0010477	response to sulfur dioxide	4.289618e-3
GO:0002457	T cell antigen processing and presentation	4.289618e-3
GO:0000088	mitotic prophase	4.289618e-3
GO:0090307	spindle assembly involved in mitosis	4.340522e-3
GO:0060821	inactivation of X chromosome by DNA methylation	4.379482e-3
GO:0010986	positive regulation of lipoprotein particle clearance	4.379482e-3
GO:0006054	N-acetylneuraminate metabolic process	4.379482e-3
GO:0018342	protein prenylation	4.527471e-3
GO:0007099	centriole replication	4.527471e-3
GO:0007192	activation of adenylate cyclase activity by serotonin receptor signaling pathway	4.544256e-3
GO:0032200	telomere organization	4.681271e-3
GO:2000822	regulation of behavioral fear response	4.732281e-3
GO:0006014	D-ribose metabolic process	4.816713e-3
GO:0016075	rRNA catabolic process	4.904707e-3
GO:0006405	RNA export from nucleus	5.065427e-3
GO:0045653	negative regulation of megakaryocyte differentiation	5.069280e-3
GO:0071455	cellular response to hyperoxia	5.069280e-3
GO:0051318	G1 phase	5.119625e-3
GO:0060154	cellular process regulating host cell cycle in response to virus	5.171650e-3
GO:0043060	meiotic metaphase I plate congression	5.494971e-3
GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	5.494971e-3
GO:0000084	S phase of mitotic cell cycle	5.565309e-3
GO:0060266	negative regulation of respiratory burst involved in inflammatory response	5.607296e-3
GO:0021986	habenula development	5.660576e-3
GO:0060236	regulation of mitotic spindle organization	5.743836e-3
GO:0010982	regulation of high-density lipoprotein particle clearance	5.743836e-3
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity	5.904895e-3
GO:0007100	mitotic centrosome separation	5.904895e-3
GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	5.904895e-3
GO:0051298	centrosome duplication	5.980223e-3
GO:0000387	spliceosomal snRNP assembly	5.980223e-3
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	5.993591e-3
GO:0006368	transcription elongation from RNA polymerase II promoter	6.098529e-3
GO:0045739	positive regulation of DNA repair	6.138394e-3
GO:0042255	ribosome assembly	6.224104e-3
GO:0051793	medium-chain fatty acid catabolic process	6.235919e-3
GO:0014888	striated muscle adaptation	6.292762e-3
GO:0014034	neural crest cell fate commitment	6.444140e-3
GO:0045190	isotype switching	6.492386e-3
GO:0001946	lymphangiogenesis	6.511142e-3
GO:0071415	cellular response to purine-containing compound	6.583170e-3
GO:0051013	microtubule severing	6.583170e-3
GO:0006426	glycyl-tRNA aminoacylation	6.583170e-3
GO:0032859	activation of Ral GTPase activity	6.683660e-3
GO:0006399	tRNA metabolic process	6.767102e-3
GO:0009225	nucleotide-sugar metabolic process	6.881193e-3
GO:0070634	transepithelial ammonium transport	7.231294e-3
GO:0017121	phospholipid scrambling	7.348671e-3
GO:0008033	tRNA processing	7.435297e-3
GO:0007521	muscle cell fate determination	7.551245e-3
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	7.819466e-3
GO:0006498	N-terminal protein lipidation	7.819466e-3
GO:0030852	regulation of granulocyte differentiation	7.866859e-3
GO:0015758	glucose transport	8.023293e-3
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	8.028425e-3
GO:0010467	gene expression	8.036201e-3
GO:0006264	mitochondrial DNA replication	8.089810e-3
GO:0006281	DNA repair	8.107833e-3
GO:0060795	cell fate commitment involved in formation of primary germ layers	8.160594e-3
GO:0045908	negative regulation of vasodilation	8.540819e-3
GO:0042109	lymphotoxin A biosynthetic process	8.540819e-3
GO:0016576	histone dephosphorylation	8.727522e-3
GO:0014740	negative regulation of muscle hyperplasia	9.023625e-3
GO:0044264	cellular polysaccharide metabolic process	9.111015e-3
GO:0016072	rRNA metabolic process	9.119716e-3
GO:0072337	modified amino acid transport	9.161217e-3
GO:0006563	L-serine metabolic process	9.171265e-3
GO:0031639	plasminogen activation	9.197380e-3
GO:0002051	osteoblast fate commitment	9.214328e-3
GO:0070370	cellular heat acclimation	9.535721e-3
GO:0006844	acyl carnitine transport	9.535721e-3
GO:0006471	protein ADP-ribosylation	9.577055e-3
GO:0061013	regulation of mRNA catabolic process	9.685076e-3
GO:0006829	zinc ion transport	9.787781e-3
GO:0021520	spinal cord motor neuron cell fate specification	1.001879e-2
GO:0035048	splicing factor protein import into nucleus	1.024173e-2
GO:0070682	proteasome regulatory particle assembly	1.024173e-2
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	1.028017e-2
GO:0070889	platelet alpha granule organization	1.030206e-2
GO:0048333	mesodermal cell differentiation	1.031867e-2
GO:0046323	glucose import	1.034949e-2
GO:0033133	positive regulation of glucokinase activity	1.034949e-2
GO:0071816	tail-anchored membrane protein insertion into ER membrane	1.041596e-2
GO:0042551	neuron maturation	1.057328e-2
GO:0003139	secondary heart field specification	1.114138e-2
GO:0031064	negative regulation of histone deacetylation	1.141317e-2
GO:0042775	mitochondrial ATP synthesis coupled electron transport	1.159595e-2
GO:0072500	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	1.160919e-2
GO:0006998	nuclear envelope organization	1.171795e-2
GO:0034645	cellular macromolecule biosynthetic process	1.203465e-2
GO:0002076	osteoblast development	1.231845e-2
GO:0001970	positive regulation of activation of membrane attack complex	1.241984e-2
GO:0032856	activation of Ras GTPase activity	1.245375e-2
GO:0042226	interleukin-6 biosynthetic process	1.248307e-2
GO:0046031	ADP metabolic process	1.248907e-2
GO:0032769	negative regulation of monooxygenase activity	1.250749e-2
GO:0045922	negative regulation of fatty acid metabolic process	1.252393e-2
GO:0032506	cytokinetic process	1.253533e-2
GO:0021569	rhombomere 3 development	1.253533e-2
GO:0090399	replicative senescence	1.268677e-2
GO:0006308	DNA catabolic process	1.281245e-2
GO:0006450	regulation of translational fidelity	1.301831e-2
GO:0033861	negative regulation of NAD(P)H oxidase activity	1.301831e-2
GO:0034154	toll-like receptor 7 signaling pathway	1.301831e-2
GO:0006478	peptidyl-tyrosine sulfation	1.301831e-2
GO:0016925	protein sumoylation	1.312725e-2
GO:0005978	glycogen biosynthetic process	1.312725e-2
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.316736e-2
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.348756e-2
GO:0045019	negative regulation of nitric oxide biosynthetic process	1.356792e-2
GO:2000300	regulation of synaptic vesicle exocytosis	1.356792e-2
GO:0033599	regulation of mammary gland epithelial cell proliferation	1.365420e-2
GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA	1.367238e-2
GO:0003094	glomerular filtration	1.367238e-2
GO:0048168	regulation of neuronal synaptic plasticity	1.414517e-2
GO:0009106	lipoate metabolic process	1.445128e-2
GO:0008588	release of cytoplasmic sequestered NF-kappaB	1.445743e-2
GO:0032855	positive regulation of Rac GTPase activity	1.458501e-2
GO:0006396	RNA processing	1.464985e-2
GO:0072655	establishment of protein localization in mitochondrion	1.465334e-2
GO:0030520	estrogen receptor signaling pathway	1.471348e-2
GO:0017148	negative regulation of translation	1.477203e-2
GO:0046967	cytosol to ER transport	1.485070e-2
GO:0060809	mesodermal to mesenchymal transition involved in gastrulation	1.485070e-2
GO:0045007	depurination	1.485070e-2
GO:0035425	autocrine signaling	1.485070e-2
GO:0002543	activation of blood coagulation via clotting cascade	1.486996e-2
GO:2001022	positive regulation of response to DNA damage stimulus	1.491911e-2
GO:0022406	membrane docking	1.495940e-2
GO:0010511	regulation of phosphatidylinositol biosynthetic process	1.496055e-2
GO:0033484	nitric oxide homeostasis	1.496055e-2
GO:0048554	positive regulation of metalloenzyme activity	1.496355e-2
GO:0045836	positive regulation of meiosis	1.505375e-2
GO:0060999	positive regulation of dendritic spine development	1.514920e-2
GO:0015696	ammonium transport	1.514920e-2
GO:0070585	protein localization in mitochondrion	1.516724e-2
GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	1.518918e-2
GO:0032862	activation of Rho GTPase activity	1.531692e-2
GO:0015788	UDP-N-acetylglucosamine transport	1.623131e-2
GO:0021586	pons maturation	1.623131e-2
GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process	1.630126e-2
GO:0003417	growth plate cartilage development	1.634835e-2
GO:0021546	rhombomere development	1.637105e-2
GO:0000271	polysaccharide biosynthetic process	1.664923e-2
GO:0046796	viral genome transport in host cell	1.672353e-2
GO:0045669	positive regulation of osteoblast differentiation	1.678945e-2
GO:0090304	nucleic acid metabolic process	1.694172e-2
GO:0003416	endochondral bone growth	1.703374e-2
GO:0006672	ceramide metabolic process	1.709682e-2
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	1.713235e-2
GO:0002691	regulation of cellular extravasation	1.713235e-2
GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	1.750079e-2
GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	1.750079e-2
GO:0030509	BMP signaling pathway	1.760775e-2
GO:0071374	cellular response to parathyroid hormone stimulus	1.764047e-2
GO:0042396	phosphagen biosynthetic process	1.800004e-2
GO:0008633	activation of pro-apoptotic gene products	1.807030e-2
GO:0070934	CRD-mediated mRNA stabilization	1.849463e-2
GO:0051260	protein homooligomerization	1.851426e-2
GO:0022004	midbrain-hindbrain boundary maturation during brain development	1.867292e-2
GO:2000002	negative regulation of DNA damage checkpoint	1.867292e-2
GO:0021551	central nervous system morphogenesis	1.867292e-2
GO:0021588	cerebellum formation	1.867292e-2
GO:0019236	response to pheromone	1.867292e-2
GO:0055089	fatty acid homeostasis	1.873440e-2
GO:2000001	regulation of DNA damage checkpoint	1.873440e-2
GO:0003329	pancreatic PP cell fate commitment	1.873440e-2
GO:0003326	pancreatic A cell fate commitment	1.873440e-2
GO:0009450	gamma-aminobutyric acid catabolic process	1.873440e-2
GO:0019254	carnitine metabolic process, CoA-linked	1.891433e-2
GO:0030262	apoptotic nuclear change	1.901563e-2
GO:0007585	respiratory gaseous exchange	1.908008e-2
GO:0033145	positive regulation of steroid hormone receptor signaling pathway	1.959849e-2
GO:0014738	regulation of muscle hyperplasia	1.967748e-2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.967748e-2
GO:0046318	negative regulation of glucosylceramide biosynthetic process	1.978701e-2
GO:0032802	low-density lipoprotein particle receptor catabolic process	1.978701e-2
GO:0009234	menaquinone biosynthetic process	1.978701e-2
GO:0008052	sensory organ boundary specification	1.978701e-2
GO:0032464	positive regulation of protein homooligomerization	1.982186e-2
GO:0070537	histone H2A K63-linked deubiquitination	1.989954e-2
GO:0045818	negative regulation of glycogen catabolic process	1.989954e-2
GO:0048341	paraxial mesoderm formation	1.998842e-2
GO:0046519	sphingoid metabolic process	1.999370e-2
GO:0072144	glomerular mesangial cell development	2.044545e-2
GO:0072011	glomerular endothelium development	2.044545e-2
GO:0046086	adenosine biosynthetic process	2.044545e-2
GO:0035873	lactate transmembrane transport	2.044545e-2
GO:0002089	lens morphogenesis in camera-type eye	2.103318e-2
GO:0048845	venous blood vessel morphogenesis	2.133836e-2
GO:0051299	centrosome separation	2.146346e-2
GO:0048935	peripheral nervous system neuron development	2.147329e-2
GO:0045046	protein import into peroxisome membrane	2.159191e-2
GO:0008334	histone mRNA metabolic process	2.201271e-2
GO:0000079	regulation of cyclin-dependent protein kinase activity	2.289982e-2
GO:0000722	telomere maintenance via recombination	2.298783e-2
GO:0051313	attachment of spindle microtubules to chromosome	2.316732e-2
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.325207e-2
GO:0021571	rhombomere 5 development	2.336593e-2
GO:0071896	protein localization to adherens junction	2.370989e-2
GO:0070483	detection of hypoxia	2.370989e-2
GO:0007182	common-partner SMAD protein phosphorylation	2.370989e-2
GO:0061037	negative regulation of cartilage development	2.377765e-2
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	2.377765e-2
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	2.403823e-2
GO:0046341	CDP-diacylglycerol metabolic process	2.403823e-2
GO:0018158	protein oxidation	2.403823e-2
GO:0001807	regulation of type IV hypersensitivity	2.403823e-2
GO:2000348	regulation of CD40 signaling pathway	2.421554e-2
GO:0022007	convergent extension involved in neural plate elongation	2.423467e-2
GO:0051256	spindle midzone assembly involved in mitosis	2.423467e-2
GO:0071217	cellular response to external biotic stimulus	2.454985e-2
GO:0031658	negative regulation of cyclin-dependent protein kinase activity involved in G1/S	2.454985e-2
GO:0006424	glutamyl-tRNA aminoacylation	2.454985e-2
GO:0007092	activation of mitotic anaphase-promoting complex activity	2.454985e-2
GO:0016142	O-glycoside catabolic process	2.454985e-2
GO:0061337	cardiac conduction	2.462527e-2
GO:0006119	oxidative phosphorylation	2.464575e-2
GO:0009313	oligosaccharide catabolic process	2.475019e-2
GO:0022617	extracellular matrix disassembly	2.475019e-2
GO:0006545	glycine biosynthetic process	2.475019e-2
GO:0045652	regulation of megakaryocyte differentiation	2.484193e-2
GO:0009059	macromolecule biosynthetic process	2.495935e-2
GO:0006359	regulation of transcription from RNA polymerase III promoter	2.500744e-2
GO:0006302	double-strand break repair	2.530931e-2
GO:0071071	regulation of phospholipid biosynthetic process	2.538392e-2
GO:0042351	'de novo' GDP-L-fucose biosynthetic process	2.577016e-2
GO:0046498	S-adenosylhomocysteine metabolic process	2.599705e-2
GO:0005977	glycogen metabolic process	2.612265e-2
GO:0006386	termination of RNA polymerase III transcription	2.662611e-2
GO:0006385	transcription elongation from RNA polymerase III promoter	2.662611e-2
GO:0019321	pentose metabolic process	2.686388e-2
GO:0046755	non-lytic virus budding	2.726064e-2
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	2.726064e-2
GO:0009785	blue light signaling pathway	2.726064e-2
GO:0051898	negative regulation of protein kinase B signaling cascade	2.752135e-2
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2.815098e-2
GO:0032508	DNA duplex unwinding	2.844208e-2
GO:0032201	telomere maintenance via semi-conservative replication	2.844208e-2
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway	2.846805e-2
GO:0034214	protein hexamerization	2.846805e-2
GO:0008355	olfactory learning	2.865905e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0044260	cellular macromolecule metabolic process	1.983640e-9
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	2.022085e-9
GO:0042048	olfactory behavior	1.644578e-8
GO:0090304	nucleic acid metabolic process	8.840370e-8
GO:0015986	ATP synthesis coupled proton transport	1.514469e-7
GO:0070858	negative regulation of bile acid biosynthetic process	6.869425e-7
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	1.672406e-6
GO:0006281	DNA repair	2.839882e-6
GO:0070857	regulation of bile acid biosynthetic process	3.296818e-6
GO:0034645	cellular macromolecule biosynthetic process	3.646313e-6
GO:0010467	gene expression	3.920628e-6
GO:0009059	macromolecule biosynthetic process	4.319174e-6
GO:0006139	nucleobase-containing compound metabolic process	4.377025e-6
GO:0018193	peptidyl-amino acid modification	1.102637e-5
GO:0006259	DNA metabolic process	1.263815e-5
GO:0071034	CUT catabolic process	1.303880e-5
GO:0046031	ADP metabolic process	1.334840e-5
GO:0006099	tricarboxylic acid cycle	1.737975e-5
GO:0006807	nitrogen compound metabolic process	1.771454e-5
GO:0048704	embryonic skeletal system morphogenesis	2.033907e-5
GO:0002098	tRNA wobble uridine modification	2.703658e-5
GO:0002536	respiratory burst involved in inflammatory response	2.912920e-5
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	3.326609e-5
GO:0090083	regulation of inclusion body assembly	3.512649e-5
GO:0007183	SMAD protein complex assembly	3.592654e-5
GO:0035137	hindlimb morphogenesis	3.747472e-5
GO:0044237	cellular metabolic process	3.877994e-5
GO:0006102	isocitrate metabolic process	4.116843e-5
GO:2001052	positive regulation of G1/S transition checkpoint	4.184638e-5
GO:0072574	hepatocyte proliferation	4.184638e-5
GO:0002194	hepatocyte cell migration	4.184638e-5
GO:0043966	histone H3 acetylation	4.480481e-5
GO:0071108	protein K48-linked deubiquitination	4.734577e-5
GO:0034641	cellular nitrogen compound metabolic process	4.737961e-5
GO:0046356	acetyl-CoA catabolic process	5.027326e-5
GO:0090084	negative regulation of inclusion body assembly	5.486047e-5
GO:0034227	tRNA thio-modification	5.486047e-5
GO:0009992	cellular water homeostasis	5.878173e-5
GO:0043170	macromolecule metabolic process	5.903280e-5
GO:0042267	natural killer cell mediated cytotoxicity	6.210783e-5
GO:0007000	nucleolus organization	7.160710e-5
GO:0060674	placenta blood vessel development	7.863733e-5
GO:0006260	DNA replication	8.274537e-5
GO:0050860	negative regulation of T cell receptor signaling pathway	8.915572e-5
GO:0009452	RNA capping	9.077546e-5
GO:0018105	peptidyl-serine phosphorylation	1.088518e-4
GO:0032077	positive regulation of deoxyribonuclease activity	1.164684e-4
GO:0070537	histone H2A K63-linked deubiquitination	1.179134e-4
GO:0009060	aerobic respiration	1.307030e-4
GO:0061003	positive regulation of dendritic spine morphogenesis	1.324939e-4
GO:0035136	forelimb morphogenesis	1.345030e-4
GO:0007635	chemosensory behavior	1.375450e-4
GO:0006308	DNA catabolic process	1.413355e-4
GO:0009109	coenzyme catabolic process	1.463993e-4
GO:0016197	endosome transport	1.798487e-4
GO:0016070	RNA metabolic process	1.904031e-4
GO:0007004	telomere maintenance via telomerase	2.115461e-4
GO:0050856	regulation of T cell receptor signaling pathway	2.223168e-4
GO:0060298	positive regulation of sarcomere organization	2.314709e-4
GO:0048935	peripheral nervous system neuron development	2.545339e-4
GO:0006756	AMP phosphorylation	2.566099e-4
GO:0001895	retina homeostasis	2.972456e-4
GO:0006603	phosphocreatine metabolic process	3.152186e-4
GO:0060708	spongiotrophoblast differentiation	3.152186e-4
GO:0072355	histone H3-T3 phosphorylation	3.395325e-4
GO:0006972	hyperosmotic response	3.644842e-4
GO:0018364	peptidyl-glutamine methylation	3.830981e-4
GO:0030070	insulin processing	3.888761e-4
GO:0071474	cellular hyperosmotic response	3.888761e-4
GO:0006013	mannose metabolic process	4.043265e-4
GO:0051187	cofactor catabolic process	4.250412e-4
GO:0009179	purine ribonucleoside diphosphate metabolic process	4.288590e-4
GO:0048025	negative regulation of nuclear mRNA splicing, via spliceosome	4.641532e-4
GO:0046619	optic placode formation involved in camera-type eye formation	4.974149e-4
GO:0015992	proton transport	5.018431e-4
GO:0035511	oxidative DNA demethylation	5.083884e-4
GO:0006657	CDP-choline pathway	5.346325e-4
GO:0071526	semaphorin-plexin signaling pathway	5.447842e-4
GO:0046940	nucleoside monophosphate phosphorylation	5.515388e-4
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	5.670907e-4
GO:0046967	cytosol to ER transport	5.874566e-4
GO:0019060	intracellular transport of viral proteins in host cell	5.874566e-4
GO:0033979	box H/ACA snoRNA metabolic process	5.874566e-4
GO:0006818	hydrogen transport	5.979834e-4
GO:0060318	definitive erythrocyte differentiation	6.137410e-4
GO:0035552	oxidative single-stranded DNA demethylation	6.155487e-4
GO:0044262	cellular carbohydrate metabolic process	6.233120e-4
GO:0030262	apoptotic nuclear change	6.292999e-4
GO:0007094	mitotic cell cycle spindle assembly checkpoint	6.374991e-4
GO:0045862	positive regulation of proteolysis	6.438307e-4
GO:0001909	leukocyte mediated cytotoxicity	6.481639e-4
GO:0021520	spinal cord motor neuron cell fate specification	6.535125e-4
GO:0044249	cellular biosynthetic process	6.803056e-4
GO:0006302	double-strand break repair	6.852942e-4
GO:0071174	mitotic cell cycle spindle checkpoint	7.408608e-4
GO:2000378	negative regulation of reactive oxygen species metabolic process	7.595291e-4
GO:0048706	embryonic skeletal system development	7.656220e-4
GO:0060179	male mating behavior	7.700200e-4
GO:0000492	box C/D snoRNP assembly	7.700200e-4
GO:0061013	regulation of mRNA catabolic process	7.801615e-4
GO:0045739	positive regulation of DNA repair	8.172678e-4
GO:0032774	RNA biosynthetic process	8.715320e-4
GO:0002483	antigen processing and presentation of endogenous peptide antigen	9.109768e-4
GO:0019673	GDP-mannose metabolic process	9.180111e-4
GO:0001743	optic placode formation	9.180111e-4
GO:0051881	regulation of mitochondrial membrane potential	9.270254e-4
GO:0035674	tricarboxylic acid transmembrane transport	9.411898e-4
GO:0008355	olfactory learning	9.411898e-4
GO:0033119	negative regulation of RNA splicing	9.620711e-4
GO:0055005	ventricular cardiac myofibril development	1.007283e-3
GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway	1.021093e-3
GO:0035269	protein O-linked mannosylation	1.047110e-3
GO:0006309	DNA fragmentation involved in apoptotic nuclear change	1.061237e-3
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	1.072757e-3
GO:0090138	regulation of actin cytoskeleton organization by cell-cell adhesion	1.081061e-3
GO:0042443	phenylethylamine metabolic process	1.081061e-3
GO:0070535	histone H2A K63-linked ubiquitination	1.081061e-3
GO:0006351	transcription, DNA-dependent	1.109966e-3
GO:0071874	cellular response to norepinephrine stimulus	1.135422e-3
GO:0002051	osteoblast fate commitment	1.167986e-3
GO:0048050	post-embryonic eye morphogenesis	1.178929e-3
GO:0006044	N-acetylglucosamine metabolic process	1.256609e-3
GO:0015012	heparan sulfate proteoglycan biosynthetic process	1.299413e-3
GO:0043631	RNA polyadenylation	1.319676e-3
GO:0071870	cellular response to catecholamine stimulus	1.412421e-3
GO:0035621	ER to Golgi ceramide transport	1.421856e-3
GO:2001022	positive regulation of response to DNA damage stimulus	1.453157e-3
GO:0035767	endothelial cell chemotaxis	1.481258e-3
GO:0006307	DNA dealkylation involved in DNA repair	1.481955e-3
GO:0051252	regulation of RNA metabolic process	1.564911e-3
GO:0046033	AMP metabolic process	1.586747e-3
GO:0060433	bronchus development	1.586747e-3
GO:0006527	arginine catabolic process	1.648916e-3
GO:0006172	ADP biosynthetic process	1.648916e-3
GO:0043407	negative regulation of MAP kinase activity	1.653059e-3
GO:0006921	cellular component disassembly involved in apoptosis	1.668706e-3
GO:0030201	heparan sulfate proteoglycan metabolic process	1.684529e-3
GO:0009058	biosynthetic process	1.767587e-3
GO:0070935	3'-UTR-mediated mRNA stabilization	1.813284e-3
GO:0000045	autophagic vacuole assembly	1.825234e-3
GO:0030953	astral microtubule organization	1.837174e-3
GO:0006023	aminoglycan biosynthetic process	2.005145e-3
GO:0050917	sensory perception of umami taste	2.012652e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	2.050510e-3
GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity	2.050510e-3
GO:0022417	protein maturation by protein folding	2.050510e-3
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	2.083359e-3
GO:2000682	positive regulation of rubidium ion transport	2.083359e-3
GO:0010430	fatty acid omega-oxidation	2.083359e-3
GO:0035826	rubidium ion transport	2.083359e-3
GO:0070989	oxidative demethylation	2.111423e-3
GO:0002679	respiratory burst involved in defense response	2.128439e-3
GO:0006378	mRNA polyadenylation	2.137754e-3
GO:2000112	regulation of cellular macromolecule biosynthetic process	2.233110e-3
GO:0035115	embryonic forelimb morphogenesis	2.315395e-3
GO:0016573	histone acetylation	2.396696e-3
GO:0048268	clathrin coat assembly	2.512421e-3
GO:0032456	endocytic recycling	2.512421e-3
GO:0060712	spongiotrophoblast layer development	2.569290e-3
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	2.569290e-3
GO:0046549	retinal cone cell development	2.569290e-3
GO:0006901	vesicle coating	2.741955e-3
GO:0000271	polysaccharide biosynthetic process	2.813027e-3
GO:0008380	RNA splicing	2.828437e-3
GO:0045333	cellular respiration	2.926180e-3
GO:0006304	DNA modification	2.941172e-3
GO:0010556	regulation of macromolecule biosynthetic process	2.971629e-3
GO:0045006	DNA deamination	2.972943e-3
GO:0006091	generation of precursor metabolites and energy	3.081356e-3
GO:0045740	positive regulation of DNA replication	3.086829e-3
GO:0002921	negative regulation of humoral immune response	3.114192e-3
GO:0006457	protein folding	3.136367e-3
GO:0018209	peptidyl-serine modification	3.173838e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	3.202681e-3
GO:0006401	RNA catabolic process	3.336585e-3
GO:0016074	snoRNA metabolic process	3.410487e-3
GO:0071173	spindle assembly checkpoint	3.411072e-3
GO:0045541	negative regulation of cholesterol biosynthetic process	3.470536e-3
GO:2000781	positive regulation of double-strand break repair	3.513407e-3
GO:0021586	pons maturation	3.513407e-3
GO:0048024	regulation of nuclear mRNA splicing, via spliceosome	3.529146e-3
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	3.543908e-3
GO:0002523	leukocyte migration involved in inflammatory response	3.543908e-3
GO:0006310	DNA recombination	3.645544e-3
GO:0006268	DNA unwinding involved in replication	3.800217e-3
GO:0010595	positive regulation of endothelial cell migration	3.821893e-3
GO:0060377	negative regulation of mast cell differentiation	3.833679e-3
GO:0006043	glucosamine catabolic process	3.833679e-3
GO:0034661	ncRNA catabolic process	3.836202e-3
GO:0006878	cellular copper ion homeostasis	3.838394e-3
GO:0001832	blastocyst growth	3.846258e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	3.951948e-3
GO:0005996	monosaccharide metabolic process	3.962468e-3
GO:0072143	mesangial cell development	3.998192e-3
GO:0045943	positive regulation of transcription from RNA polymerase I promoter	3.998192e-3
GO:0010468	regulation of gene expression	4.023612e-3
GO:0060272	embryonic skeletal joint morphogenesis	4.070672e-3
GO:0021658	rhombomere 3 morphogenesis	4.097225e-3
GO:0060434	bronchus morphogenesis	4.097225e-3
GO:0048280	vesicle fusion with Golgi apparatus	4.097225e-3
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	4.097225e-3
GO:0009202	deoxyribonucleoside triphosphate biosynthetic process	4.097225e-3
GO:0010833	telomere maintenance via telomere lengthening	4.097225e-3
GO:0010890	positive regulation of sequestering of triglyceride	4.097225e-3
GO:0046939	nucleotide phosphorylation	4.138084e-3
GO:0050868	negative regulation of T cell activation	4.191203e-3
GO:0051568	histone H3-K4 methylation	4.206685e-3
GO:0010894	negative regulation of steroid biosynthetic process	4.206685e-3
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	4.264861e-3
GO:0018393	internal peptidyl-lysine acetylation	4.324047e-3
GO:0048701	embryonic cranial skeleton morphogenesis	4.398099e-3
GO:0031122	cytoplasmic microtubule organization	4.440578e-3
GO:0045190	isotype switching	4.455487e-3
GO:0072133	metanephric mesenchyme morphogenesis	4.459313e-3
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	4.524522e-3
GO:0031558	induction of apoptosis in response to chemical stimulus	4.682126e-3
GO:0016236	macroautophagy	4.733963e-3
GO:0018394	peptidyl-lysine acetylation	4.784160e-3
GO:0009185	ribonucleoside diphosphate metabolic process	4.794058e-3
GO:0035116	embryonic hindlimb morphogenesis	4.846218e-3
GO:0018107	peptidyl-threonine phosphorylation	4.915303e-3
GO:0002063	chondrocyte development	4.969940e-3
GO:0015746	citrate transport	5.027184e-3
GO:0008216	spermidine metabolic process	5.027184e-3
GO:0006475	internal protein amino acid acetylation	5.107004e-3
GO:0032287	peripheral nervous system myelin maintenance	5.157472e-3
GO:0030166	proteoglycan biosynthetic process	5.187133e-3
GO:0046907	intracellular transport	5.209326e-3
GO:0072498	embryonic skeletal joint development	5.247580e-3
GO:0060255	regulation of macromolecule metabolic process	5.311820e-3
GO:0048665	neuron fate specification	5.326336e-3
GO:0018205	peptidyl-lysine modification	5.378681e-3
GO:0043951	negative regulation of cAMP-mediated signaling	5.409070e-3
GO:0070318	positive regulation of G0 to G1 transition	5.409070e-3
GO:0060064	Spemann organizer formation at the anterior end of the primitive streak	5.417732e-3
GO:0046596	regulation of virion penetration into host cell	5.417732e-3
GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	5.417732e-3
GO:0045992	negative regulation of embryonic development	5.417732e-3
GO:0042840	D-glucuronate catabolic process	5.417732e-3
GO:0016052	carbohydrate catabolic process	5.444487e-3
GO:0035966	response to topologically incorrect protein	5.657000e-3
GO:0007090	regulation of S phase of mitotic cell cycle	5.661827e-3
GO:0006355	regulation of transcription, DNA-dependent	5.675149e-3
GO:0048814	regulation of dendrite morphogenesis	5.693858e-3
GO:0022027	interkinetic nuclear migration	5.694526e-3
GO:0030104	water homeostasis	5.699657e-3
GO:0045839	negative regulation of mitosis	5.699657e-3
GO:0002904	positive regulation of B cell apoptosis	5.715325e-3
GO:0006275	regulation of DNA replication	5.727669e-3
GO:0009142	nucleoside triphosphate biosynthetic process	5.731151e-3
GO:0060214	endocardium formation	5.854596e-3
GO:0045581	negative regulation of T cell differentiation	5.923454e-3
GO:0060999	positive regulation of dendritic spine development	6.063913e-3
GO:0001967	suckling behavior	6.093644e-3
GO:0003160	endocardium morphogenesis	6.170887e-3
GO:0044275	cellular carbohydrate catabolic process	6.188873e-3
GO:0031577	spindle checkpoint	6.293703e-3
GO:0055070	copper ion homeostasis	6.355728e-3
GO:0006473	protein acetylation	6.379391e-3
GO:0006782	protoporphyrinogen IX biosynthetic process	6.446239e-3
GO:0070166	enamel mineralization	6.493148e-3
GO:0008633	activation of pro-apoptotic gene products	6.574249e-3
GO:0032508	DNA duplex unwinding	6.609845e-3
GO:0016578	histone deubiquitination	6.609845e-3
GO:0046039	GTP metabolic process	6.660598e-3
GO:0071044	histone mRNA catabolic process	6.916010e-3
GO:0070407	oxidation-dependent protein catabolic process	6.922996e-3
GO:0006348	chromatin silencing at telomere	6.922996e-3
GO:0070370	cellular heat acclimation	6.922996e-3
GO:0033327	Leydig cell differentiation	7.135470e-3
GO:0006024	glycosaminoglycan biosynthetic process	7.180534e-3
GO:0050775	positive regulation of dendrite morphogenesis	7.302140e-3
GO:0006184	GTP catabolic process	7.397234e-3
GO:0007422	peripheral nervous system development	7.409315e-3
GO:0072593	reactive oxygen species metabolic process	7.410507e-3
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	7.459138e-3
GO:0060317	cardiac epithelial to mesenchymal transition	7.588231e-3
GO:0060297	regulation of sarcomere organization	7.588231e-3
GO:0006396	RNA processing	7.617171e-3
GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity	7.720724e-3
GO:0046882	negative regulation of follicle-stimulating hormone secretion	7.720724e-3
GO:0046015	regulation of transcription by glucose	7.733200e-3
GO:0032392	DNA geometric change	7.816784e-3
GO:0015790	UDP-xylose transport	7.832869e-3
GO:0048697	positive regulation of collateral sprouting in absence of injury	7.832869e-3
GO:0015788	UDP-N-acetylglucosamine transport	7.832869e-3
GO:0012502	induction of programmed cell death	7.898563e-3
GO:0006974	response to DNA damage stimulus	7.902960e-3
GO:0071901	negative regulation of protein serine/threonine kinase activity	7.982363e-3
GO:0045931	positive regulation of mitotic cell cycle	8.089194e-3
GO:0071422	succinate transmembrane transport	8.107510e-3
GO:0001830	trophectodermal cell fate commitment	8.107510e-3
GO:0016139	glycoside catabolic process	8.107510e-3
GO:0042474	middle ear morphogenesis	8.118173e-3
GO:0044238	primary metabolic process	8.298421e-3
GO:0006282	regulation of DNA repair	8.369106e-3
GO:0009154	purine ribonucleotide catabolic process	8.411897e-3
GO:0006917	induction of apoptosis	8.469964e-3
GO:0042069	regulation of catecholamine metabolic process	8.480500e-3
GO:0016572	histone phosphorylation	8.651936e-3
GO:0051054	positive regulation of DNA metabolic process	8.699273e-3
GO:0010741	negative regulation of intracellular protein kinase cascade	8.914249e-3
GO:0080111	DNA demethylation	9.067424e-3
GO:0072098	anterior/posterior pattern specification involved in kidney development	9.100680e-3
GO:0048389	intermediate mesoderm development	9.100680e-3
GO:0019348	dolichol metabolic process	9.100680e-3
GO:0043409	negative regulation of MAPKKK cascade	9.164258e-3
GO:0050684	regulation of mRNA processing	9.260380e-3
GO:0003188	heart valve formation	9.334463e-3
GO:0019730	antimicrobial humoral response	9.361330e-3
GO:0009150	purine ribonucleotide metabolic process	9.696187e-3
GO:0030326	embryonic limb morphogenesis	9.826686e-3
GO:0043508	negative regulation of JUN kinase activity	9.936736e-3
GO:0035510	DNA dealkylation	9.936736e-3
GO:0071460	cellular response to cell-matrix adhesion	1.002629e-2
GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	1.002629e-2
GO:0035553	oxidative single-stranded RNA demethylation	1.002629e-2
GO:0042364	water-soluble vitamin biosynthetic process	1.003704e-2
GO:0042147	retrograde transport, endosome to Golgi	1.011498e-2
GO:0009141	nucleoside triphosphate metabolic process	1.040348e-2
GO:0060319	primitive erythrocyte differentiation	1.043666e-2
GO:0019852	L-ascorbic acid metabolic process	1.043902e-2
GO:0030818	negative regulation of cAMP biosynthetic process	1.053804e-2
GO:0070316	regulation of G0 to G1 transition	1.064156e-2
GO:0044154	histone H3-K14 acetylation	1.064156e-2
GO:0000956	nuclear-transcribed mRNA catabolic process	1.066814e-2
GO:0060061	Spemann organizer formation	1.078645e-2
GO:0001709	cell fate determination	1.093922e-2
GO:0061001	regulation of dendritic spine morphogenesis	1.106280e-2
GO:0009143	nucleoside triphosphate catabolic process	1.112097e-2
GO:0042733	embryonic digit morphogenesis	1.135171e-2
GO:0019432	triglyceride biosynthetic process	1.137781e-2
GO:0051403	stress-activated MAPK cascade	1.138514e-2
GO:0018210	peptidyl-threonine modification	1.149687e-2
GO:0009261	ribonucleotide catabolic process	1.153758e-2
GO:0072190	ureter urothelium development	1.159898e-2
GO:0019853	L-ascorbic acid biosynthetic process	1.168994e-2
GO:0007033	vacuole organization	1.181228e-2
GO:0018108	peptidyl-tyrosine phosphorylation	1.181228e-2
GO:0016050	vesicle organization	1.181228e-2
GO:0060219	camera-type eye photoreceptor cell differentiation	1.213023e-2
GO:0090086	negative regulation of protein deubiquitination	1.221643e-2
GO:0033603	positive regulation of dopamine secretion	1.221643e-2
GO:0046709	IDP catabolic process	1.235149e-2
GO:0046032	ADP catabolic process	1.235149e-2
GO:0070571	negative regulation of neuron projection regeneration	1.245991e-2
GO:0022038	corpus callosum development	1.246827e-2
GO:0071845	cellular component disassembly at cellular level	1.247577e-2
GO:0042554	superoxide anion generation	1.284233e-2
GO:0009146	purine nucleoside triphosphate catabolic process	1.326525e-2
GO:0070164	negative regulation of adiponectin secretion	1.339718e-2
GO:0045769	negative regulation of asymmetric cell division	1.339718e-2
GO:0090241	negative regulation of histone H4 acetylation	1.339718e-2
GO:0035505	positive regulation of myosin light chain kinase activity	1.339718e-2
GO:0014908	myotube differentiation involved in skeletal muscle regeneration	1.339718e-2
GO:0034401	regulation of transcription by chromatin organization	1.339718e-2
GO:0007518	myoblast cell fate determination	1.339718e-2
GO:0009145	purine nucleoside triphosphate biosynthetic process	1.361456e-2
GO:0043983	histone H4-K12 acetylation	1.362596e-2
GO:0061136	regulation of proteasomal protein catabolic process	1.365787e-2
GO:0009207	purine ribonucleoside triphosphate catabolic process	1.369664e-2
GO:0051705	behavioral interaction between organisms	1.375470e-2
GO:0006986	response to unfolded protein	1.375470e-2
GO:0006801	superoxide metabolic process	1.387098e-2
GO:0061312	BMP signaling pathway involved in heart development	1.400687e-2
GO:0002268	follicular dendritic cell differentiation	1.400687e-2
GO:0019430	removal of superoxide radicals	1.401102e-2
GO:0045662	negative regulation of myoblast differentiation	1.416532e-2
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	1.423820e-2
GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation	1.423820e-2
GO:0071539	protein localization to centrosome	1.429817e-2
GO:0001834	trophectodermal cell proliferation	1.429817e-2
GO:0006235	dTTP biosynthetic process	1.429817e-2
GO:0031326	regulation of cellular biosynthetic process	1.447725e-2
GO:0002312	B cell activation involved in immune response	1.448193e-2
GO:0022411	cellular component disassembly	1.453701e-2
GO:0006195	purine nucleotide catabolic process	1.460878e-2
GO:0019219	regulation of nucleobase-containing compound metabolic process	1.464092e-2
GO:0006040	amino sugar metabolic process	1.467050e-2
GO:0009231	riboflavin biosynthetic process	1.469025e-2
GO:0046463	acylglycerol biosynthetic process	1.472978e-2
GO:0009889	regulation of biosynthetic process	1.502587e-2
GO:0005975	carbohydrate metabolic process	1.528073e-2
GO:0006734	NADH metabolic process	1.564340e-2
GO:0072132	mesenchyme morphogenesis	1.568118e-2
GO:0035284	brain segmentation	1.568269e-2
GO:0060684	epithelial-mesenchymal cell signaling	1.601798e-2
GO:0060414	aorta smooth muscle tissue morphogenesis	1.617224e-2
GO:0006397	mRNA processing	1.627297e-2
GO:0032277	negative regulation of gonadotropin secretion	1.630891e-2
GO:0034214	protein hexamerization	1.630891e-2
GO:0007403	glial cell fate determination	1.630891e-2
GO:0009144	purine nucleoside triphosphate metabolic process	1.655725e-2
GO:0010821	regulation of mitochondrion organization	1.657700e-2
GO:0030240	skeletal muscle thin filament assembly	1.699362e-2
GO:0009259	ribonucleotide metabolic process	1.729786e-2
GO:0042130	negative regulation of T cell proliferation	1.735901e-2
GO:0009205	purine ribonucleoside triphosphate metabolic process	1.742703e-2
GO:0042245	RNA repair	1.745855e-2
GO:0042727	flavin-containing compound biosynthetic process	1.745855e-2
GO:0021660	rhombomere 3 formation	1.745855e-2
GO:0021666	rhombomere 5 formation	1.745855e-2
GO:0002352	B cell negative selection	1.745855e-2
GO:0072144	glomerular mesangial cell development	1.749212e-2
GO:0048312	intracellular distribution of mitochondria	1.749212e-2
GO:0045014	negative regulation of transcription by glucose	1.749212e-2
GO:0043217	myelin maintenance	1.756650e-2
GO:0051148	negative regulation of muscle cell differentiation	1.758841e-2
GO:0051220	cytoplasmic sequestering of protein	1.772500e-2
GO:0019048	virus-host interaction	1.805440e-2
GO:0045980	negative regulation of nucleotide metabolic process	1.816660e-2
GO:0009199	ribonucleoside triphosphate metabolic process	1.830164e-2
GO:0050916	sensory perception of sweet taste	1.838072e-2
GO:0045299	otolith mineralization	1.838072e-2
GO:0000917	barrier septum formation	1.838072e-2
GO:0015781	pyrimidine nucleotide-sugar transport	1.838072e-2
GO:0006914	autophagy	1.840076e-2
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	1.857033e-2
GO:0006289	nucleotide-excision repair	1.868687e-2
GO:0031123	RNA 3'-end processing	1.879830e-2
GO:0046855	inositol phosphate dephosphorylation	1.884204e-2
GO:0016051	carbohydrate biosynthetic process	1.888160e-2
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	1.894299e-2
GO:0006767	water-soluble vitamin metabolic process	1.899622e-2
GO:0006402	mRNA catabolic process	1.917646e-2
GO:0031323	regulation of cellular metabolic process	1.923415e-2
GO:0016071	mRNA metabolic process	1.946068e-2
GO:0051171	regulation of nitrogen compound metabolic process	1.946766e-2
GO:0001710	mesodermal cell fate commitment	1.959795e-2
GO:0055015	ventricular cardiac muscle cell development	1.997850e-2
GO:0003009	skeletal muscle contraction	1.997850e-2
GO:0033692	cellular polysaccharide biosynthetic process	2.004960e-2
GO:0070925	organelle assembly	2.008082e-2
GO:0048663	neuron fate commitment	2.013360e-2
GO:0048488	synaptic vesicle endocytosis	2.029333e-2
GO:0046501	protoporphyrinogen IX metabolic process	2.053057e-2
GO:0071733	transcriptional activation by promoter-enhancer looping	2.053057e-2
GO:2000774	positive regulation of cellular senescence	2.060102e-2
GO:0090402	oncogene-induced senescence	2.060102e-2
GO:0035986	senescence-associated heterochromatin focus formation	2.060102e-2
GO:0060421	positive regulation of heart growth	2.060102e-2
GO:0060440	trachea formation	2.060102e-2
GO:0010544	negative regulation of platelet activation	2.060991e-2
GO:0045730	respiratory burst	2.069503e-2
GO:0050925	negative regulation of negative chemotaxis	2.102865e-2
GO:0042696	menarche	2.102865e-2
GO:0006084	acetyl-CoA metabolic process	2.125110e-2
GO:0044070	regulation of anion transport	2.157397e-2
GO:0016142	O-glycoside catabolic process	2.160792e-2
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	2.160792e-2
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	2.160792e-2
GO:0045833	negative regulation of lipid metabolic process	2.169408e-2
GO:0009152	purine ribonucleotide biosynthetic process	2.208664e-2
GO:0008624	induction of apoptosis by extracellular signals	2.222325e-2
GO:0060350	endochondral bone morphogenesis	2.224709e-2
GO:0016265	death	2.254321e-2
GO:0070230	positive regulation of lymphocyte apoptosis	2.261308e-2
GO:0009166	nucleotide catabolic process	2.291514e-2
GO:0042119	neutrophil activation	2.294904e-2
GO:0072134	nephrogenic mesenchyme morphogenesis	2.304060e-2
GO:0060709	glycogen cell development involved in embryonic placenta development	2.304060e-2
GO:0046185	aldehyde catabolic process	2.304060e-2
GO:0032481	positive regulation of type I interferon production	2.313687e-2
GO:0021795	cerebral cortex cell migration	2.325001e-2
GO:0015804	neutral amino acid transport	2.347261e-2
GO:0072523	purine-containing compound catabolic process	2.364609e-2
GO:0008612	peptidyl-lysine modification to hypusine	2.368950e-2
GO:0002331	pre-B cell allelic exclusion	2.368950e-2
GO:0019543	propionate catabolic process	2.391399e-2
GO:0007617	mating behavior	2.409435e-2
GO:0070100	negative regulation of chemokine-mediated signaling pathway	2.445492e-2
GO:0045750	positive regulation of S phase of mitotic cell cycle	2.445492e-2
GO:0003157	endocardium development	2.454811e-2
GO:0014037	Schwann cell differentiation	2.466834e-2
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	2.584836e-2
GO:0010948	negative regulation of cell cycle process	2.589685e-2
GO:0006270	DNA-dependent DNA replication initiation	2.655566e-2
GO:0090096	positive regulation of metanephric cap mesenchymal cell proliferation	2.655792e-2
GO:0090185	negative regulation of kidney development	2.655792e-2
GO:0051124	synaptic growth at neuromuscular junction	2.655792e-2
GO:0010511	regulation of phosphatidylinositol biosynthetic process	2.655792e-2
GO:0051081	nuclear envelope disassembly	2.655792e-2
GO:0008608	attachment of spindle microtubules to kinetochore	2.655792e-2
GO:0021759	globus pallidus development	2.655792e-2
GO:0045620	negative regulation of lymphocyte differentiation	2.675322e-2
GO:0050854	regulation of antigen receptor-mediated signaling pathway	2.690349e-2
GO:2000377	regulation of reactive oxygen species metabolic process	2.699887e-2
GO:0006900	membrane budding	2.712484e-2
GO:0006888	ER to Golgi vesicle-mediated transport	2.715826e-2
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	2.725160e-2
GO:0006491	N-glycan processing	2.801187e-2
GO:0070536	protein K63-linked deubiquitination	2.808665e-2
GO:0046504	glycerol ether biosynthetic process	2.808665e-2
GO:0000381	regulation of alternative nuclear mRNA splicing, via spliceosome	2.835736e-2
GO:0015980	energy derivation by oxidation of organic compounds	2.852903e-2
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	2.869350e-2
GO:0021569	rhombomere 3 development	2.869350e-2
GO:0060466	activation of meiosis involved in egg activation	2.869350e-2
GO:0034110	regulation of homotypic cell-cell adhesion	2.877588e-2
GO:0072239	metanephric glomerulus vasculature development	2.877588e-2