Novel motif:72

name:	motif72_CAGAAMC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0002576	platelet degranulation	8.364571e-15
GO:0009611	response to wounding	8.331120e-14
GO:0001775	cell activation	7.539861e-13
GO:0006955	immune response	2.148706e-12
GO:0030241	skeletal muscle myosin thick filament assembly	4.375170e-12
GO:0007076	mitotic chromosome condensation	7.709162e-12
GO:0006952	defense response	5.178709e-11
GO:0048769	sarcomerogenesis	7.215056e-11
GO:0030168	platelet activation	1.378414e-10
GO:0007599	hemostasis	1.607562e-10
GO:0042060	wound healing	1.672471e-10
GO:0002376	immune system process	1.733694e-10
GO:0007596	blood coagulation	2.026674e-10
GO:0030185	nitric oxide transport	6.987985e-10
GO:0014866	skeletal myofibril assembly	1.576334e-9
GO:0007067	mitosis	2.631496e-9
GO:0030240	skeletal muscle thin filament assembly	2.719111e-9
GO:0019221	cytokine-mediated signaling pathway	3.160384e-9
GO:0000087	M phase of mitotic cell cycle	4.602877e-9
GO:0000279	M phase	4.627049e-9
GO:0070252	actin-mediated cell contraction	4.950787e-9
GO:0030049	muscle filament sliding	5.800229e-9
GO:0030421	defecation	9.583524e-9
GO:0006950	response to stress	3.260399e-8
GO:0030048	actin filament-based movement	4.110668e-8
GO:0007614	short-term memory	4.154354e-8
GO:0048285	organelle fission	5.476570e-8
GO:0050878	regulation of body fluid levels	5.795216e-8
GO:0032101	regulation of response to external stimulus	7.266213e-8
GO:0015671	oxygen transport	8.505451e-8
GO:0000070	mitotic sister chromatid segregation	1.004696e-7
GO:0050715	positive regulation of cytokine secretion	1.390612e-7
GO:0033555	multicellular organismal response to stress	1.408231e-7
GO:0043550	regulation of lipid kinase activity	1.487638e-7
GO:0007015	actin filament organization	1.496018e-7
GO:0000819	sister chromatid segregation	1.628814e-7
GO:0033003	regulation of mast cell activation	1.736080e-7
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	2.098824e-7
GO:0048739	cardiac muscle fiber development	2.180786e-7
GO:0055013	cardiac muscle cell development	2.185623e-7
GO:0034097	response to cytokine stimulus	2.431207e-7
GO:0006768	biotin metabolic process	2.854724e-7
GO:0002407	dendritic cell chemotaxis	3.537005e-7
GO:0055003	cardiac myofibril assembly	3.762955e-7
GO:0003012	muscle system process	4.295594e-7
GO:0006486	protein glycosylation	5.683882e-7
GO:0006936	muscle contraction	6.242400e-7
GO:0050680	negative regulation of epithelial cell proliferation	6.453044e-7
GO:0042221	response to chemical stimulus	8.933556e-7
GO:0006364	rRNA processing	1.010732e-6
GO:0070085	glycosylation	1.115578e-6
GO:0032940	secretion by cell	1.196874e-6
GO:0006887	exocytosis	1.278567e-6
GO:0022402	cell cycle process	1.303088e-6
GO:0031100	organ regeneration	1.390107e-6
GO:0021629	olfactory nerve structural organization	1.447732e-6
GO:0071844	cellular component assembly at cellular level	1.516677e-6
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.588196e-6
GO:0071345	cellular response to cytokine stimulus	1.626292e-6
GO:0030595	leukocyte chemotaxis	1.732453e-6
GO:0034063	stress granule assembly	2.203561e-6
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	2.264853e-6
GO:0007166	cell surface receptor linked signaling pathway	2.482069e-6
GO:0050795	regulation of behavior	2.742419e-6
GO:0006688	glycosphingolipid biosynthetic process	3.031338e-6
GO:0048266	behavioral response to pain	3.175386e-6
GO:0051592	response to calcium ion	3.259608e-6
GO:0016072	rRNA metabolic process	3.358042e-6
GO:0031347	regulation of defense response	3.396677e-6
GO:0030261	chromosome condensation	3.544653e-6
GO:0000414	regulation of histone H3-K36 methylation	4.125115e-6
GO:0050707	regulation of cytokine secretion	4.169176e-6
GO:0031929	TOR signaling cascade	5.052302e-6
GO:0050896	response to stimulus	5.456848e-6
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	5.486681e-6
GO:0042320	regulation of circadian sleep/wake cycle, REM sleep	5.618474e-6
GO:0050714	positive regulation of protein secretion	5.734482e-6
GO:0090218	positive regulation of lipid kinase activity	5.836600e-6
GO:0006335	DNA replication-dependent nucleosome assembly	6.718827e-6
GO:0042178	xenobiotic catabolic process	7.584349e-6
GO:0000416	positive regulation of histone H3-K36 methylation	7.713001e-6
GO:0006552	leucine catabolic process	7.767173e-6
GO:0051338	regulation of transferase activity	7.900220e-6
GO:0009101	glycoprotein biosynthetic process	1.220387e-5
GO:0042254	ribosome biogenesis	1.329400e-5
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	1.347649e-5
GO:0033993	response to lipid	1.423170e-5
GO:0016525	negative regulation of angiogenesis	1.507958e-5
GO:0009100	glycoprotein metabolic process	1.556302e-5
GO:0043623	cellular protein complex assembly	1.668829e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	1.691710e-5
GO:0030277	maintenance of gastrointestinal epithelium	1.706200e-5
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.823299e-5
GO:0071841	cellular component organization or biogenesis at cellular level	1.989595e-5
GO:0007584	response to nutrient	2.159137e-5
GO:0043549	regulation of kinase activity	2.280801e-5
GO:0048535	lymph node development	2.509289e-5
GO:0042596	fear response	2.616659e-5
GO:0046903	secretion	2.670252e-5
GO:0007613	memory	2.766041e-5
GO:0009566	fertilization	2.840161e-5
GO:0045214	sarcomere organization	3.012463e-5
GO:0019216	regulation of lipid metabolic process	3.088908e-5
GO:0050790	regulation of catalytic activity	3.092018e-5
GO:0032846	positive regulation of homeostatic process	3.236414e-5
GO:0071034	CUT catabolic process	3.488149e-5
GO:0035414	negative regulation of catenin import into nucleus	3.669759e-5
GO:0006928	cellular component movement	4.015129e-5
GO:0007338	single fertilization	4.033019e-5
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4.238037e-5
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	4.272367e-5
GO:0051445	regulation of meiotic cell cycle	4.566348e-5
GO:0001574	ganglioside biosynthetic process	4.702535e-5
GO:0042744	hydrogen peroxide catabolic process	4.776355e-5
GO:0080134	regulation of response to stress	5.215783e-5
GO:0048747	muscle fiber development	5.447146e-5
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	5.677368e-5
GO:0051384	response to glucocorticoid stimulus	5.718162e-5
GO:0015669	gas transport	5.744953e-5
GO:0022613	ribonucleoprotein complex biogenesis	5.778636e-5
GO:0046426	negative regulation of JAK-STAT cascade	5.809610e-5
GO:0040020	regulation of meiosis	5.869069e-5
GO:0071934	thiamine transmembrane transport	6.197552e-5
GO:0046491	L-methylmalonyl-CoA metabolic process	6.197552e-5
GO:0002682	regulation of immune system process	6.587092e-5
GO:0060675	ureteric bud morphogenesis	6.590714e-5
GO:0007049	cell cycle	6.614833e-5
GO:0007018	microtubule-based movement	6.798624e-5
GO:0032367	intracellular cholesterol transport	7.809081e-5
GO:0050779	RNA destabilization	7.870482e-5
GO:0000086	G2/M transition of mitotic cell cycle	8.112537e-5
GO:0045859	regulation of protein kinase activity	8.329317e-5
GO:0014068	positive regulation of phosphatidylinositol 3-kinase cascade	8.724397e-5
GO:0008354	germ cell migration	8.755668e-5
GO:0006968	cellular defense response	9.565227e-5
GO:0002694	regulation of leukocyte activation	9.596677e-5
GO:0060084	synaptic transmission involved in micturition	9.843643e-5
GO:0014048	regulation of glutamate secretion	9.886248e-5
GO:0006551	leucine metabolic process	1.028685e-4
GO:0030534	adult behavior	1.036564e-4
GO:0043302	positive regulation of leukocyte degranulation	1.040799e-4
GO:0051902	negative regulation of mitochondrial depolarization	1.067831e-4
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.072754e-4
GO:0050865	regulation of cell activation	1.106350e-4
GO:0034723	DNA replication-dependent nucleosome organization	1.107750e-4
GO:0007050	cell cycle arrest	1.175508e-4
GO:0048679	regulation of axon regeneration	1.183177e-4
GO:0009607	response to biotic stimulus	1.203239e-4
GO:0007259	JAK-STAT cascade	1.207671e-4
GO:0065009	regulation of molecular function	1.217537e-4
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	1.248763e-4
GO:0030321	transepithelial chloride transport	1.255058e-4
GO:0031667	response to nutrient levels	1.307975e-4
GO:0001658	branching involved in ureteric bud morphogenesis	1.357696e-4
GO:0034699	response to luteinizing hormone stimulus	1.374342e-4
GO:0010035	response to inorganic substance	1.407447e-4
GO:0001831	trophectodermal cellular morphogenesis	1.452688e-4
GO:0002443	leukocyte mediated immunity	1.476314e-4
GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep	1.548894e-4
GO:0051085	chaperone mediated protein folding requiring cofactor	1.728297e-4
GO:0033235	positive regulation of protein sumoylation	1.728297e-4
GO:0010633	negative regulation of epithelial cell migration	1.759048e-4
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	1.780650e-4
GO:0008216	spermidine metabolic process	1.796530e-4
GO:0051017	actin filament bundle assembly	1.836328e-4
GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	1.874981e-4
GO:0048070	regulation of developmental pigmentation	1.879598e-4
GO:0032103	positive regulation of response to external stimulus	1.945981e-4
GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	2.012897e-4
GO:0051047	positive regulation of secretion	2.052550e-4
GO:0032844	regulation of homeostatic process	2.056025e-4
GO:0051240	positive regulation of multicellular organismal process	2.063749e-4
GO:0002118	aggressive behavior	2.130283e-4
GO:0051336	regulation of hydrolase activity	2.177160e-4
GO:0033006	regulation of mast cell activation involved in immune response	2.189084e-4
GO:0048584	positive regulation of response to stimulus	2.258682e-4
GO:0031581	hemidesmosome assembly	2.273691e-4
GO:0021553	olfactory nerve development	2.290158e-4
GO:0002696	positive regulation of leukocyte activation	2.379547e-4
GO:0045087	innate immune response	2.390257e-4
GO:0031032	actomyosin structure organization	2.426908e-4
GO:0033522	histone H2A ubiquitination	2.539289e-4
GO:0007029	endoplasmic reticulum organization	2.549082e-4
GO:0043306	positive regulation of mast cell degranulation	2.559565e-4
GO:0034661	ncRNA catabolic process	2.593183e-4
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	2.604828e-4
GO:0008361	regulation of cell size	2.654197e-4
GO:0030224	monocyte differentiation	2.666134e-4
GO:0042572	retinol metabolic process	2.673668e-4
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.711624e-4
GO:0007096	regulation of exit from mitosis	2.782285e-4
GO:0006582	melanin metabolic process	2.800815e-4
GO:0051297	centrosome organization	2.917104e-4
GO:0031023	microtubule organizing center organization	2.989289e-4
GO:0008628	induction of apoptosis by hormones	2.989951e-4
GO:0050708	regulation of protein secretion	3.001245e-4
GO:0022600	digestive system process	3.053389e-4
GO:0042508	tyrosine phosphorylation of Stat1 protein	3.125428e-4
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	3.148007e-4
GO:0006721	terpenoid metabolic process	3.168625e-4
GO:0016101	diterpenoid metabolic process	3.187436e-4
GO:0050764	regulation of phagocytosis	3.249075e-4
GO:0006776	vitamin A metabolic process	3.386508e-4
GO:0048512	circadian behavior	3.390918e-4
GO:0001523	retinoid metabolic process	3.449626e-4
GO:0030239	myofibril assembly	3.467723e-4
GO:0006921	cellular component disassembly involved in apoptosis	3.486751e-4
GO:0051322	anaphase	3.504034e-4
GO:0048583	regulation of response to stimulus	3.527583e-4
GO:0043300	regulation of leukocyte degranulation	3.542425e-4
GO:0010523	negative regulation of calcium ion transport into cytosol	3.546288e-4
GO:0046685	response to arsenic-containing substance	3.564759e-4
GO:0042982	amyloid precursor protein metabolic process	3.569411e-4
GO:0006711	estrogen catabolic process	3.583951e-4
GO:0071843	cellular component biogenesis at cellular level	3.610503e-4
GO:0034622	cellular macromolecular complex assembly	3.613914e-4
GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein	3.638628e-4
GO:0050920	regulation of chemotaxis	3.921551e-4
GO:0048554	positive regulation of metalloenzyme activity	3.991065e-4
GO:0000090	mitotic anaphase	4.022333e-4
GO:0008624	induction of apoptosis by extracellular signals	4.094165e-4
GO:0046425	regulation of JAK-STAT cascade	4.198189e-4
GO:0030325	adrenal gland development	4.224886e-4
GO:0009726	detection of endogenous stimulus	4.310135e-4
GO:0035461	vitamin transmembrane transport	4.428847e-4
GO:0050867	positive regulation of cell activation	4.452798e-4
GO:0000188	inactivation of MAPK activity	4.558132e-4
GO:0035048	splicing factor protein import into nucleus	4.656054e-4
GO:0042921	glucocorticoid receptor signaling pathway	4.743326e-4
GO:0050818	regulation of coagulation	4.765987e-4
GO:0009888	tissue development	4.808912e-4
GO:0009214	cyclic nucleotide catabolic process	4.813089e-4
GO:0009615	response to virus	4.838215e-4
GO:0042325	regulation of phosphorylation	4.840096e-4
GO:0002268	follicular dendritic cell differentiation	4.843623e-4
GO:0032287	peripheral nervous system myelin maintenance	4.848505e-4
GO:0014889	muscle atrophy	4.880649e-4
GO:0042506	tyrosine phosphorylation of Stat5 protein	5.060898e-4
GO:0007626	locomotory behavior	5.179069e-4
GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein	5.185737e-4
GO:0048521	negative regulation of behavior	5.216069e-4
GO:0051302	regulation of cell division	5.216905e-4
GO:0019220	regulation of phosphate metabolic process	5.223971e-4
GO:0001824	blastocyst development	5.240859e-4
GO:0007406	negative regulation of neuroblast proliferation	5.307351e-4
GO:0001662	behavioral fear response	5.441684e-4
GO:0033005	positive regulation of mast cell activation	5.453758e-4
GO:0002886	regulation of myeloid leukocyte mediated immunity	5.584696e-4
GO:0008284	positive regulation of cell proliferation	5.590001e-4
GO:0042438	melanin biosynthetic process	5.629952e-4
GO:0045835	negative regulation of meiosis	5.650879e-4
GO:0006290	pyrimidine dimer repair	5.729703e-4
GO:0006954	inflammatory response	5.855769e-4
GO:0009247	glycolipid biosynthetic process	5.858546e-4
GO:0021846	cell proliferation in forebrain	5.862024e-4
GO:0061028	establishment of endothelial barrier	6.147010e-4
GO:0031099	regeneration	6.179894e-4
GO:0006941	striated muscle contraction	6.340019e-4
GO:0022403	cell cycle phase	6.397383e-4
GO:0002699	positive regulation of immune effector process	6.517661e-4
GO:0045187	regulation of circadian sleep/wake cycle, sleep	6.672584e-4
GO:0021847	ventricular zone neuroblast division	6.686735e-4
GO:0050922	negative regulation of chemotaxis	6.703965e-4
GO:0016064	immunoglobulin mediated immune response	6.722565e-4
GO:0043217	myelin maintenance	6.789967e-4
GO:0048520	positive regulation of behavior	6.803074e-4
GO:0046732	active induction of host immune response by virus	6.869798e-4
GO:0050776	regulation of immune response	6.895715e-4
GO:0006720	isoprenoid metabolic process	6.973543e-4
GO:0043090	amino acid import	7.015502e-4
GO:0035066	positive regulation of histone acetylation	7.073404e-4
GO:0042745	circadian sleep/wake cycle	7.095132e-4
GO:0032571	response to vitamin K	7.299480e-4
GO:0071840	cellular component organization or biogenesis	7.443146e-4
GO:0019724	B cell mediated immunity	7.476799e-4
GO:0042753	positive regulation of circadian rhythm	7.492510e-4
GO:0050819	negative regulation of coagulation	7.510548e-4
GO:0002675	positive regulation of acute inflammatory response	7.684562e-4
GO:0060326	cell chemotaxis	7.757882e-4
GO:0034754	cellular hormone metabolic process	7.780926e-4
GO:0031468	nuclear envelope reassembly	7.785922e-4
GO:0007100	mitotic centrosome separation	7.785922e-4
GO:0003008	system process	7.830591e-4
GO:0071842	cellular component organization at cellular level	7.869147e-4
GO:0043627	response to estrogen stimulus	8.017685e-4
GO:0009605	response to external stimulus	8.053867e-4
GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	8.160821e-4
GO:0071731	response to nitric oxide	8.222247e-4
GO:0051707	response to other organism	8.269113e-4
GO:0010742	macrophage derived foam cell differentiation	8.350743e-4
GO:0035695	mitochondrion degradation by induced vacuole formation	8.442218e-4
GO:0001881	receptor recycling	8.527784e-4
GO:0032102	negative regulation of response to external stimulus	8.697466e-4
GO:0022410	circadian sleep/wake cycle process	8.729894e-4
GO:0002209	behavioral defense response	8.779331e-4
GO:0002684	positive regulation of immune system process	8.833619e-4
GO:0001932	regulation of protein phosphorylation	8.837912e-4
GO:0031960	response to corticosteroid stimulus	8.909273e-4
GO:0030029	actin filament-based process	9.039647e-4
GO:0035039	male pronucleus assembly	9.096413e-4
GO:0046069	cGMP catabolic process	9.197861e-4
GO:0045346	regulation of MHC class II biosynthetic process	9.361271e-4
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	9.714550e-4
GO:0055007	cardiac muscle cell differentiation	9.825420e-4
GO:0007586	digestion	9.862115e-4
GO:0019932	second-messenger-mediated signaling	9.880983e-4
GO:0044330	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing	9.913229e-4
GO:0044328	canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration	9.913229e-4
GO:0044329	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion	9.913229e-4
GO:0051235	maintenance of location	9.935277e-4
GO:0032501	multicellular organismal process	9.961180e-4
GO:0007416	synapse assembly	1.005390e-3
GO:0042742	defense response to bacterium	1.006141e-3
GO:0050727	regulation of inflammatory response	1.024946e-3
GO:0006598	polyamine catabolic process	1.026985e-3
GO:0050900	leukocyte migration	1.028195e-3
GO:0033159	negative regulation of protein import into nucleus, translocation	1.053248e-3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	1.056254e-3
GO:0051347	positive regulation of transferase activity	1.070183e-3
GO:0060356	leucine import	1.129040e-3
GO:0006508	proteolysis	1.134900e-3
GO:0032507	maintenance of protein location in cell	1.137851e-3
GO:0034621	cellular macromolecular complex subunit organization	1.147311e-3
GO:0051480	cytosolic calcium ion homeostasis	1.192446e-3
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	1.205729e-3
GO:0009991	response to extracellular stimulus	1.209186e-3
GO:0017187	peptidyl-glutamic acid carboxylation	1.214955e-3
GO:0045347	negative regulation of MHC class II biosynthetic process	1.216965e-3
GO:0002526	acute inflammatory response	1.217757e-3
GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	1.222231e-3
GO:0031622	positive regulation of fever generation	1.255279e-3
GO:0044085	cellular component biogenesis	1.273145e-3
GO:0070171	negative regulation of tooth mineralization	1.279747e-3
GO:0031120	snRNA pseudouridine synthesis	1.294874e-3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	1.294874e-3
GO:0045911	positive regulation of DNA recombination	1.295732e-3
GO:0010743	regulation of macrophage derived foam cell differentiation	1.298781e-3
GO:0045948	positive regulation of translational initiation	1.315981e-3
GO:0007010	cytoskeleton organization	1.320037e-3
GO:0010837	regulation of keratinocyte proliferation	1.328623e-3
GO:0043116	negative regulation of vascular permeability	1.335378e-3
GO:0051279	regulation of release of sequestered calcium ion into cytosol	1.337992e-3
GO:0034112	positive regulation of homotypic cell-cell adhesion	1.347319e-3
GO:0048545	response to steroid hormone stimulus	1.375814e-3
GO:0010632	regulation of epithelial cell migration	1.376965e-3
GO:0010669	epithelial structure maintenance	1.379431e-3
GO:0048265	response to pain	1.384570e-3
GO:0010466	negative regulation of peptidase activity	1.389700e-3
GO:0007156	homophilic cell adhesion	1.405599e-3
GO:0002449	lymphocyte mediated immunity	1.414785e-3
GO:0030593	neutrophil chemotaxis	1.416167e-3
GO:0030148	sphingolipid biosynthetic process	1.423240e-3
GO:0006775	fat-soluble vitamin metabolic process	1.429213e-3
GO:0006198	cAMP catabolic process	1.489510e-3
GO:0043368	positive T cell selection	1.489846e-3
GO:0007343	egg activation	1.494706e-3
GO:0045321	leukocyte activation	1.495139e-3
GO:0051649	establishment of localization in cell	1.495949e-3
GO:0043112	receptor metabolic process	1.582917e-3
GO:0042119	neutrophil activation	1.599530e-3
GO:0010951	negative regulation of endopeptidase activity	1.605798e-3
GO:2000178	negative regulation of neural precursor cell proliferation	1.635854e-3
GO:0043304	regulation of mast cell degranulation	1.635854e-3
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	1.636181e-3
GO:0045213	neurotransmitter receptor metabolic process	1.639277e-3
GO:0071344	diphosphate metabolic process	1.653747e-3
GO:0006493	protein O-linked glycosylation	1.655804e-3
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway	1.655968e-3
GO:0033674	positive regulation of kinase activity	1.680764e-3
GO:0060594	mammary gland specification	1.707965e-3
GO:0050907	detection of chemical stimulus involved in sensory perception	1.729405e-3
GO:0045780	positive regulation of bone resorption	1.749883e-3
GO:0010310	regulation of hydrogen peroxide metabolic process	1.753226e-3
GO:0001657	ureteric bud development	1.792392e-3
GO:0050919	negative chemotaxis	1.796671e-3
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	1.798852e-3
GO:0045058	T cell selection	1.803518e-3
GO:0007274	neuromuscular synaptic transmission	1.821040e-3
GO:0055099	response to high density lipoprotein particle stimulus	1.823154e-3
GO:0016075	rRNA catabolic process	1.823154e-3
GO:0014894	response to denervation involved in regulation of muscle adaptation	1.836136e-3
GO:0002573	myeloid leukocyte differentiation	1.872074e-3
GO:0010522	regulation of calcium ion transport into cytosol	1.881369e-3
GO:0008593	regulation of Notch signaling pathway	1.884193e-3
GO:0050808	synapse organization	1.885952e-3
GO:0031508	centromeric heterochromatin formation	1.907083e-3
GO:0055008	cardiac muscle tissue morphogenesis	1.907821e-3
GO:0071241	cellular response to inorganic substance	1.912729e-3
GO:0071887	leukocyte apoptosis	1.941164e-3
GO:0035235	ionotropic glutamate receptor signaling pathway	1.963143e-3
GO:0032801	receptor catabolic process	1.976213e-3
GO:0051938	L-glutamate import	2.000630e-3
GO:0000278	mitotic cell cycle	2.007062e-3
GO:0045638	negative regulation of myeloid cell differentiation	2.007489e-3
GO:0031958	corticosteroid receptor signaling pathway	2.026021e-3
GO:0044003	modification by symbiont of host morphology or physiology	2.053184e-3
GO:0007181	transforming growth factor beta receptor complex assembly	2.084819e-3
GO:0007610	behavior	2.106683e-3
GO:0007165	signal transduction	2.119592e-3
GO:0007176	regulation of epidermal growth factor-activated receptor activity	2.129685e-3
GO:0018916	nitrobenzene metabolic process	2.130086e-3
GO:0009399	nitrogen fixation	2.130086e-3
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	2.149857e-3
GO:0070286	axonemal dynein complex assembly	2.169994e-3
GO:0009125	nucleoside monophosphate catabolic process	2.205439e-3
GO:0031652	positive regulation of heat generation	2.230304e-3
GO:0006323	DNA packaging	2.267442e-3
GO:0016192	vesicle-mediated transport	2.326177e-3
GO:0050911	detection of chemical stimulus involved in sensory perception of smell	2.364598e-3
GO:0061017	hepatoblast differentiation	2.364775e-3
GO:0071103	DNA conformation change	2.384721e-3
GO:0050783	cocaine metabolic process	2.422270e-3
GO:0007275	multicellular organismal development	2.450259e-3
GO:0061387	regulation of extent of cell growth	2.460656e-3
GO:0018108	peptidyl-tyrosine phosphorylation	2.487553e-3
GO:0060713	labyrinthine layer morphogenesis	2.524109e-3
GO:0007017	microtubule-based process	2.558132e-3
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	2.569499e-3
GO:0014874	response to stimulus involved in regulation of muscle adaptation	2.569499e-3
GO:0051258	protein polymerization	2.601171e-3
GO:0042503	tyrosine phosphorylation of Stat3 protein	2.636874e-3
GO:0015918	sterol transport	2.638356e-3
GO:0045861	negative regulation of proteolysis	2.640213e-3
GO:0001906	cell killing	2.669875e-3
GO:0010511	regulation of phosphatidylinositol biosynthetic process	2.683498e-3
GO:0046434	organophosphate catabolic process	2.688632e-3
GO:0030301	cholesterol transport	2.717436e-3
GO:0010656	negative regulation of muscle cell apoptosis	2.718341e-3
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	2.719167e-3
GO:0009817	defense response to fungus, incompatible interaction	2.719167e-3
GO:0019836	hemolysis by symbiont of host erythrocytes	2.723859e-3
GO:0010935	regulation of macrophage cytokine production	2.728959e-3
GO:0010535	positive regulation of activation of JAK2 kinase activity	2.736094e-3
GO:0044093	positive regulation of molecular function	2.769655e-3
GO:0010587	miRNA catabolic process	2.774347e-3
GO:0051054	positive regulation of DNA metabolic process	2.781254e-3
GO:0051345	positive regulation of hydrolase activity	2.789278e-3
GO:0010038	response to metal ion	2.854944e-3
GO:0048638	regulation of developmental growth	2.861990e-3
GO:0043406	positive regulation of MAP kinase activity	2.868310e-3
GO:0009408	response to heat	2.950498e-3
GO:0071712	ER-associated misfolded protein catabolic process	2.971405e-3
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	2.980094e-3
GO:0031116	positive regulation of microtubule polymerization	2.980094e-3
GO:0010667	negative regulation of cardiac muscle cell apoptosis	3.006596e-3
GO:0032845	negative regulation of homeostatic process	3.023429e-3
GO:0001934	positive regulation of protein phosphorylation	3.032215e-3
GO:0007213	muscarinic acetylcholine receptor signaling pathway	3.070696e-3
GO:0012501	programmed cell death	3.099637e-3
GO:0046102	inosine metabolic process	3.108938e-3
GO:0007622	rhythmic behavior	3.109903e-3
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	3.146951e-3
GO:0043402	glucocorticoid mediated signaling pathway	3.176593e-3
GO:0017121	phospholipid scrambling	3.186506e-3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	3.195795e-3
GO:0043500	muscle adaptation	3.222421e-3
GO:0033209	tumor necrosis factor-mediated signaling pathway	3.245969e-3
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	3.260572e-3
GO:0030162	regulation of proteolysis	3.285684e-3
GO:0070305	response to cGMP	3.291537e-3
GO:0010536	positive regulation of activation of Janus kinase activity	3.291537e-3
GO:0021869	forebrain ventricular zone progenitor cell division	3.305995e-3
GO:0046649	lymphocyte activation	3.330927e-3
GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	3.341905e-3
GO:2000639	negative regulation of SREBP-mediated signaling pathway	3.397998e-3
GO:2000346	negative regulation of hepatocyte proliferation	3.397998e-3
GO:0010745	negative regulation of macrophage derived foam cell differentiation	3.486476e-3
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	3.500304e-3
GO:0006857	oligopeptide transport	3.506348e-3
GO:0050771	negative regulation of axonogenesis	3.530318e-3
GO:0007157	heterophilic cell-cell adhesion	3.532376e-3
GO:0033962	cytoplasmic mRNA processing body assembly	3.641527e-3
GO:0006888	ER to Golgi vesicle-mediated transport	3.650952e-3
GO:0007204	elevation of cytosolic calcium ion concentration	3.675217e-3
GO:0071902	positive regulation of protein serine/threonine kinase activity	3.681328e-3
GO:0048075	positive regulation of eye pigmentation	3.702412e-3
GO:0048691	positive regulation of axon extension involved in regeneration	3.702412e-3
GO:0019056	modulation by virus of host transcription	3.702412e-3
GO:0030518	steroid hormone receptor signaling pathway	3.708413e-3
GO:0019058	viral infectious cycle	3.719275e-3
GO:0031110	regulation of microtubule polymerization or depolymerization	3.737670e-3
GO:0000720	pyrimidine dimer repair by nucleotide-excision repair	3.760571e-3
GO:0010996	response to auditory stimulus	3.760571e-3
GO:0045185	maintenance of protein location	3.797648e-3
GO:0048880	sensory system development	3.845207e-3
GO:0050892	intestinal absorption	3.901576e-3
GO:0032455	nerve growth factor processing	3.950456e-3
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	3.950456e-3
GO:0002768	immune response-regulating cell surface receptor signaling pathway	3.963371e-3
GO:0071321	cellular response to cGMP	3.977777e-3
GO:0046148	pigment biosynthetic process	3.982633e-3
GO:0043085	positive regulation of catalytic activity	4.028877e-3
GO:0045907	positive regulation of vasoconstriction	4.034376e-3
GO:0043420	anthranilate metabolic process	4.056612e-3
GO:0034516	response to vitamin B6	4.056612e-3
GO:0051045	negative regulation of membrane protein ectodomain proteolysis	4.128146e-3
GO:0015817	histidine transport	4.131512e-3
GO:0046856	phosphatidylinositol dephosphorylation	4.135847e-3
GO:0048087	positive regulation of developmental pigmentation	4.147384e-3
GO:0045879	negative regulation of smoothened signaling pathway	4.168179e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0010715	regulation of extracellular matrix disassembly	2.083192e-8
GO:0042069	regulation of catecholamine metabolic process	2.083192e-8
GO:0006950	response to stress	2.635627e-8
GO:0007612	learning	4.085345e-8
GO:0008306	associative learning	4.937856e-8
GO:0042053	regulation of dopamine metabolic process	8.117494e-8
GO:0035634	response to stilbenoid	3.804171e-7
GO:0042060	wound healing	9.041311e-7
GO:0035106	operant conditioning	1.106883e-6
GO:0070474	positive regulation of uterine smooth muscle contraction	1.126862e-6
GO:0060841	venous blood vessel development	1.199882e-6
GO:0009611	response to wounding	1.333613e-6
GO:0055090	acylglycerol homeostasis	2.136911e-6
GO:0031424	keratinization	2.596099e-6
GO:0002209	behavioral defense response	3.119598e-6
GO:0006952	defense response	3.644040e-6
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	3.761329e-6
GO:0001662	behavioral fear response	4.214556e-6
GO:0042596	fear response	4.260129e-6
GO:0016998	cell wall macromolecule catabolic process	4.319579e-6
GO:0042744	hydrogen peroxide catabolic process	4.550486e-6
GO:0000722	telomere maintenance via recombination	4.684654e-6
GO:0000028	ribosomal small subunit assembly	5.354156e-6
GO:0010765	positive regulation of sodium ion transport	6.970436e-6
GO:0045760	positive regulation of action potential	8.480927e-6
GO:0002286	T cell activation involved in immune response	8.541377e-6
GO:0010466	negative regulation of peptidase activity	9.760276e-6
GO:0033555	multicellular organismal response to stress	1.020909e-5
GO:0034441	plasma lipoprotein particle oxidation	1.054976e-5
GO:0048149	behavioral response to ethanol	1.122660e-5
GO:0034599	cellular response to oxidative stress	1.205912e-5
GO:0043270	positive regulation of ion transport	1.220775e-5
GO:0050668	positive regulation of homocysteine metabolic process	1.292277e-5
GO:0045963	negative regulation of dopamine metabolic process	1.292277e-5
GO:0071702	organic substance transport	1.314792e-5
GO:0045087	innate immune response	1.581103e-5
GO:0002238	response to molecule of fungal origin	1.905854e-5
GO:0034442	regulation of lipoprotein oxidation	1.922051e-5
GO:0048845	venous blood vessel morphogenesis	2.074170e-5
GO:0072148	epithelial cell fate commitment	2.074170e-5
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	2.124157e-5
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	2.218522e-5
GO:0030836	positive regulation of actin filament depolymerization	2.289297e-5
GO:0019934	cGMP-mediated signaling	2.727528e-5
GO:0051409	response to nitrosative stress	2.775652e-5
GO:0010632	regulation of epithelial cell migration	3.302491e-5
GO:0070301	cellular response to hydrogen peroxide	3.378419e-5
GO:0006188	IMP biosynthetic process	3.432235e-5
GO:0031123	RNA 3'-end processing	3.767580e-5
GO:0050748	negative regulation of lipoprotein metabolic process	3.958396e-5
GO:0001659	temperature homeostasis	3.971757e-5
GO:0070842	aggresome assembly	4.292718e-5
GO:0044062	regulation of excretion	4.387368e-5
GO:0007611	learning or memory	4.642159e-5
GO:0002540	leukotriene production involved in inflammatory response	4.661748e-5
GO:0030799	regulation of cyclic nucleotide metabolic process	4.716777e-5
GO:0032241	positive regulation of nucleobase-containing compound transport	4.759126e-5
GO:0051176	positive regulation of sulfur metabolic process	4.999476e-5
GO:0010716	negative regulation of extracellular matrix disassembly	4.999476e-5
GO:0007219	Notch signaling pathway	5.048809e-5
GO:0007186	G-protein coupled receptor protein signaling pathway	5.235262e-5
GO:0001945	lymph vessel development	5.547816e-5
GO:0045648	positive regulation of erythrocyte differentiation	5.931974e-5
GO:0065009	regulation of molecular function	6.097689e-5
GO:0043252	sodium-independent organic anion transport	6.542246e-5
GO:0002702	positive regulation of production of molecular mediator of immune response	6.612613e-5
GO:0046958	nonassociative learning	6.739072e-5
GO:0009956	radial pattern formation	6.861977e-5
GO:0048521	negative regulation of behavior	6.866451e-5
GO:0019932	second-messenger-mediated signaling	7.531756e-5
GO:0050896	response to stimulus	7.974188e-5
GO:0070368	positive regulation of hepatocyte differentiation	8.010175e-5
GO:0060836	lymphatic endothelial cell differentiation	8.077244e-5
GO:0045639	positive regulation of myeloid cell differentiation	8.097187e-5
GO:0070846	Hsp90 deacetylation	8.659958e-5
GO:0090042	tubulin deacetylation	8.659958e-5
GO:0051961	negative regulation of nervous system development	8.788399e-5
GO:0060849	regulation of transcription involved in lymphatic endothelial cell fate commitment	9.212808e-5
GO:0060193	positive regulation of lipase activity	9.569671e-5
GO:0006189	'de novo' IMP biosynthetic process	1.055314e-4
GO:0051893	regulation of focal adhesion assembly	1.069855e-4
GO:0006620	posttranslational protein targeting to membrane	1.070630e-4
GO:0003008	system process	1.131708e-4
GO:0015872	dopamine transport	1.142155e-4
GO:0060157	urinary bladder development	1.168439e-4
GO:0048843	negative regulation of axon extension involved in axon guidance	1.168439e-4
GO:0034635	glutathione transport	1.169282e-4
GO:0033238	regulation of cellular amine metabolic process	1.183912e-4
GO:0032229	negative regulation of synaptic transmission, GABAergic	1.223604e-4
GO:0032924	activin receptor signaling pathway	1.269156e-4
GO:0044092	negative regulation of molecular function	1.341991e-4
GO:0032239	regulation of nucleobase-containing compound transport	1.479158e-4
GO:0003093	regulation of glomerular filtration	1.528116e-4
GO:0006982	response to lipid hydroperoxide	1.539103e-4
GO:0060055	angiogenesis involved in wound healing	1.580233e-4
GO:0045446	endothelial cell differentiation	1.584347e-4
GO:0060839	endothelial cell fate commitment	1.618091e-4
GO:0019370	leukotriene biosynthetic process	1.637668e-4
GO:0060578	superior vena cava morphogenesis	1.646520e-4
GO:0035229	positive regulation of glutamate-cysteine ligase activity	1.646520e-4
GO:0008616	queuosine biosynthetic process	1.709767e-4
GO:0030814	regulation of cAMP metabolic process	1.744412e-4
GO:0032674	regulation of interleukin-5 production	1.887882e-4
GO:0050890	cognition	1.995740e-4
GO:0090196	regulation of chemokine secretion	2.011097e-4
GO:0034340	response to type I interferon	2.011695e-4
GO:0042772	DNA damage response, signal transduction resulting in transcription	2.012999e-4
GO:0003350	pulmonary myocardium development	2.075281e-4
GO:0006637	acyl-CoA metabolic process	2.231821e-4
GO:0051973	positive regulation of telomerase activity	2.251703e-4
GO:0051346	negative regulation of hydrolase activity	2.273062e-4
GO:0060158	activation of phospholipase C activity by dopamine receptor signaling pathway	2.280953e-4
GO:0003158	endothelium development	2.309158e-4
GO:0051289	protein homotetramerization	2.419342e-4
GO:0006812	cation transport	2.518448e-4
GO:0042221	response to chemical stimulus	2.525829e-4
GO:0042743	hydrogen peroxide metabolic process	2.553535e-4
GO:0035813	regulation of renal sodium excretion	2.641037e-4
GO:0045764	positive regulation of cellular amino acid metabolic process	2.663606e-4
GO:0042424	catecholamine catabolic process	2.928175e-4
GO:0043086	negative regulation of catalytic activity	2.968811e-4
GO:0009629	response to gravity	3.000142e-4
GO:0032900	negative regulation of neurotrophin production	3.214921e-4
GO:0032244	positive regulation of nucleoside transport	3.214921e-4
GO:0048239	negative regulation of DNA recombination at telomere	3.259440e-4
GO:0006430	lysyl-tRNA aminoacylation	3.259440e-4
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	3.259440e-4
GO:0032714	negative regulation of interleukin-5 production	3.263256e-4
GO:0090197	positive regulation of chemokine secretion	3.433582e-4
GO:0033194	response to hydroperoxide	3.435825e-4
GO:0060460	left lung morphogenesis	3.617040e-4
GO:0002331	pre-B cell allelic exclusion	3.646972e-4
GO:0030001	metal ion transport	3.676681e-4
GO:0051964	negative regulation of synapse assembly	3.710375e-4
GO:0060381	positive regulation of single-stranded telomeric DNA binding	3.791715e-4
GO:0046986	negative regulation of hemoglobin biosynthetic process	3.791715e-4
GO:0043538	regulation of actin phosphorylation	3.791715e-4
GO:0031161	phosphatidylinositol catabolic process	3.791715e-4
GO:0030194	positive regulation of blood coagulation	3.818006e-4
GO:0006312	mitotic recombination	3.829799e-4
GO:0071277	cellular response to calcium ion	4.031228e-4
GO:0042663	regulation of endodermal cell fate specification	4.113517e-4
GO:0051894	positive regulation of focal adhesion assembly	4.537214e-4
GO:0043269	regulation of ion transport	4.579499e-4
GO:0006691	leukotriene metabolic process	4.628407e-4
GO:0030817	regulation of cAMP biosynthetic process	4.729049e-4
GO:0032101	regulation of response to external stimulus	4.750594e-4
GO:0050790	regulation of catalytic activity	4.802412e-4
GO:0001661	conditioned taste aversion	4.888908e-4
GO:0050820	positive regulation of coagulation	4.949597e-4
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway	5.056881e-4
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.086191e-4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.086191e-4
GO:0034614	cellular response to reactive oxygen species	5.088453e-4
GO:0002251	organ or tissue specific immune response	5.482076e-4
GO:0032200	telomere organization	5.539587e-4
GO:0042697	menopause	5.820750e-4
GO:0090035	positive regulation of cellular chaperone-mediated protein complex assembly	5.965800e-4
GO:0042274	ribosomal small subunit biogenesis	5.984473e-4
GO:0000729	DNA double-strand break processing	6.183391e-4
GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger	6.211569e-4
GO:0060577	pulmonary vein morphogenesis	6.255568e-4
GO:0035964	COPI-coated vesicle budding	6.255568e-4
GO:0030802	regulation of cyclic nucleotide biosynthetic process	6.361754e-4
GO:0014049	positive regulation of glutamate secretion	6.592146e-4
GO:0010033	response to organic substance	6.716023e-4
GO:0071248	cellular response to metal ion	6.750662e-4
GO:0033628	regulation of cell adhesion mediated by integrin	6.861904e-4
GO:0032102	negative regulation of response to external stimulus	7.120967e-4
GO:0070198	protein localization to chromosome, telomeric region	7.298105e-4
GO:0014889	muscle atrophy	7.493399e-4
GO:0071241	cellular response to inorganic substance	7.747511e-4
GO:0034097	response to cytokine stimulus	7.879288e-4
GO:0055085	transmembrane transport	8.017456e-4
GO:0030033	microvillus assembly	8.024691e-4
GO:0003285	septum secundum development	8.024691e-4
GO:0003278	apoptosis involved in heart morphogenesis	8.072837e-4
GO:0007632	visual behavior	8.084899e-4
GO:0030490	maturation of SSU-rRNA	8.529130e-4
GO:0015844	monoamine transport	8.586625e-4
GO:0006820	anion transport	8.645234e-4
GO:0030517	negative regulation of axon extension	8.681152e-4
GO:0051928	positive regulation of calcium ion transport	8.933419e-4
GO:0060576	intestinal epithelial cell development	9.211383e-4
GO:0035553	oxidative single-stranded RNA demethylation	9.385779e-4
GO:0002720	positive regulation of cytokine production involved in immune response	9.432815e-4
GO:0008542	visual learning	9.689098e-4
GO:0001934	positive regulation of protein phosphorylation	9.795879e-4
GO:0051260	protein homooligomerization	9.811231e-4
GO:0034625	fatty acid elongation, monounsaturated fatty acid	9.901653e-4
GO:0050891	multicellular organismal water homeostasis	9.939124e-4
GO:0042048	olfactory behavior	1.001071e-3
GO:0001913	T cell mediated cytotoxicity	1.001071e-3
GO:0020027	hemoglobin metabolic process	1.007166e-3
GO:0031125	rRNA 3'-end processing	1.011508e-3
GO:0006508	proteolysis	1.017335e-3
GO:0015711	organic anion transport	1.108317e-3
GO:0071286	cellular response to magnesium ion	1.135098e-3
GO:0060206	estrous cycle phase	1.136267e-3
GO:0060837	blood vessel endothelial cell differentiation	1.152268e-3
GO:0015817	histidine transport	1.152268e-3
GO:0042420	dopamine catabolic process	1.152268e-3
GO:0001977	renal system process involved in regulation of blood volume	1.155350e-3
GO:0032782	bile acid secretion	1.256887e-3
GO:0072355	histone H3-T3 phosphorylation	1.256887e-3
GO:0010725	regulation of primitive erythrocyte differentiation	1.256887e-3
GO:0003096	renal sodium ion transport	1.256887e-3
GO:0019428	allantoin biosynthetic process	1.256887e-3
GO:0031081	nuclear pore distribution	1.277545e-3
GO:0001975	response to amphetamine	1.285017e-3
GO:0097070	ductus arteriosus closure	1.306736e-3
GO:0007202	activation of phospholipase C activity	1.344513e-3
GO:0050848	regulation of calcium-mediated signaling	1.356242e-3
GO:0019935	cyclic-nucleotide-mediated signaling	1.360083e-3
GO:0007212	dopamine receptor signaling pathway	1.370628e-3
GO:0031401	positive regulation of protein modification process	1.380338e-3
GO:0014048	regulation of glutamate secretion	1.383136e-3
GO:0035552	oxidative single-stranded DNA demethylation	1.393885e-3
GO:0006749	glutathione metabolic process	1.394772e-3
GO:0006955	immune response	1.420088e-3
GO:0043628	ncRNA 3'-end processing	1.438269e-3
GO:0046456	icosanoid biosynthetic process	1.450171e-3
GO:0030801	positive regulation of cyclic nucleotide metabolic process	1.461126e-3
GO:0045072	regulation of interferon-gamma biosynthetic process	1.475904e-3
GO:0000738	DNA catabolic process, exonucleolytic	1.501620e-3
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.503736e-3
GO:0045401	positive regulation of interleukin-3 biosynthetic process	1.503736e-3
GO:0032696	negative regulation of interleukin-13 production	1.539406e-3
GO:0043116	negative regulation of vascular permeability	1.566718e-3
GO:0071805	potassium ion transmembrane transport	1.568736e-3
GO:0006144	purine base metabolic process	1.572037e-3
GO:0006308	DNA catabolic process	1.589170e-3
GO:0090072	positive regulation of sodium ion transport via voltage-gated sodium channel activity	1.591687e-3
GO:0048769	sarcomerogenesis	1.623843e-3
GO:0009443	pyridoxal 5'-phosphate salvage	1.623843e-3
GO:0035457	cellular response to interferon-alpha	1.625913e-3
GO:0016078	tRNA catabolic process	1.628552e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	1.628552e-3
GO:0003259	cardioblast anterior-lateral migration	1.628552e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	1.628552e-3
GO:0001682	tRNA 5'-leader removal	1.628552e-3
GO:0003210	cardiac atrium formation	1.628552e-3
GO:0003236	sinus venosus morphogenesis	1.628552e-3
GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	1.640438e-3
GO:0050746	regulation of lipoprotein metabolic process	1.691127e-3
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1.705881e-3
GO:0033058	directional locomotion	1.716245e-3
GO:2000021	regulation of ion homeostasis	1.719313e-3
GO:0045777	positive regulation of blood pressure	1.756887e-3
GO:0030216	keratinocyte differentiation	1.875766e-3
GO:0007166	cell surface receptor linked signaling pathway	1.905271e-3
GO:0035621	ER to Golgi ceramide transport	2.010227e-3
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	2.010227e-3
GO:0033159	negative regulation of protein import into nucleus, translocation	2.023879e-3
GO:0045937	positive regulation of phosphate metabolic process	2.035216e-3
GO:0043501	skeletal muscle adaptation	2.093209e-3
GO:0002385	mucosal immune response	2.118099e-3
GO:0008643	carbohydrate transport	2.132843e-3
GO:0050850	positive regulation of calcium-mediated signaling	2.144133e-3
GO:0006833	water transport	2.160637e-3
GO:0034370	triglyceride-rich lipoprotein particle remodeling	2.165367e-3
GO:0010518	positive regulation of phospholipase activity	2.174629e-3
GO:0071705	nitrogen compound transport	2.194593e-3
GO:0050771	negative regulation of axonogenesis	2.217076e-3
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	2.228435e-3
GO:0006867	asparagine transport	2.228435e-3
GO:0072376	protein activation cascade	2.230412e-3
GO:2000249	regulation of actin cytoskeleton reorganization	2.243515e-3
GO:0010959	regulation of metal ion transport	2.247032e-3
GO:0010876	lipid localization	2.290742e-3
GO:0065008	regulation of biological quality	2.291342e-3
GO:0002118	aggressive behavior	2.303592e-3
GO:0006111	regulation of gluconeogenesis	2.325719e-3
GO:0007160	cell-matrix adhesion	2.337164e-3
GO:0003018	vascular process in circulatory system	2.365254e-3
GO:0009628	response to abiotic stimulus	2.385681e-3
GO:0003209	cardiac atrium morphogenesis	2.410935e-3
GO:0000723	telomere maintenance	2.411802e-3
GO:0006956	complement activation	2.439723e-3
GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	2.456846e-3
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	2.476460e-3
GO:0051915	induction of synaptic plasticity by chemical substance	2.481411e-3
GO:0007625	grooming behavior	2.498002e-3
GO:0060907	positive regulation of macrophage cytokine production	2.511963e-3
GO:0002639	positive regulation of immunoglobulin production	2.524571e-3
GO:0032268	regulation of cellular protein metabolic process	2.540831e-3
GO:0071816	tail-anchored membrane protein insertion into ER membrane	2.545499e-3
GO:0032210	regulation of telomere maintenance via telomerase	2.545499e-3
GO:0031440	regulation of mRNA 3'-end processing	2.572843e-3
GO:0031848	protection from non-homologous end joining at telomere	2.577363e-3
GO:0032202	telomere assembly	2.577363e-3
GO:0006407	rRNA export from nucleus	2.577363e-3
GO:0006438	valyl-tRNA aminoacylation	2.577363e-3
GO:0002069	columnar/cuboidal epithelial cell maturation	2.577363e-3
GO:0006636	unsaturated fatty acid biosynthetic process	2.662021e-3
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.669751e-3
GO:0032844	regulation of homeostatic process	2.681090e-3
GO:0045672	positive regulation of osteoclast differentiation	2.714800e-3
GO:0052547	regulation of peptidase activity	2.735504e-3
GO:0009415	response to water	2.779043e-3
GO:0071345	cellular response to cytokine stimulus	2.782961e-3
GO:0008635	activation of caspase activity by cytochrome c	2.827131e-3
GO:0021542	dentate gyrus development	2.863503e-3
GO:0009635	response to herbicide	2.912111e-3
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis	3.087745e-3
GO:0051592	response to calcium ion	3.094735e-3
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	3.127678e-3
GO:0051025	negative regulation of immunoglobulin secretion	3.127678e-3
GO:0031915	positive regulation of synaptic plasticity	3.156029e-3
GO:0002252	immune effector process	3.157069e-3
GO:0043631	RNA polyadenylation	3.174832e-3
GO:0071221	cellular response to bacterial lipopeptide	3.186533e-3
GO:0007631	feeding behavior	3.296507e-3
GO:0010517	regulation of phospholipase activity	3.336690e-3
GO:0042044	fluid transport	3.344151e-3
GO:0007029	endoplasmic reticulum organization	3.371700e-3
GO:0006750	glutathione biosynthetic process	3.388140e-3
GO:0034372	very-low-density lipoprotein particle remodeling	3.411682e-3
GO:0070245	positive regulation of thymocyte apoptosis	3.422368e-3
GO:0070344	regulation of fat cell proliferation	3.431974e-3
GO:0002227	innate immune response in mucosa	3.431974e-3
GO:0097006	regulation of plasma lipoprotein particle levels	3.433021e-3
GO:0071875	adrenergic receptor signaling pathway	3.433435e-3
GO:0048016	inositol phosphate-mediated signaling	3.446765e-3
GO:0050818	regulation of coagulation	3.486510e-3
GO:0070350	regulation of white fat cell proliferation	3.495430e-3
GO:0010565	regulation of cellular ketone metabolic process	3.498590e-3
GO:0006869	lipid transport	3.514336e-3
GO:0048266	behavioral response to pain	3.540823e-3
GO:0009191	ribonucleoside diphosphate catabolic process	3.544919e-3
GO:0043402	glucocorticoid mediated signaling pathway	3.567120e-3
GO:0002532	production of molecular mediator involved in inflammatory response	3.578427e-3
GO:0000186	activation of MAPKK activity	3.724018e-3
GO:0010832	negative regulation of myotube differentiation	3.729015e-3
GO:0051900	regulation of mitochondrial depolarization	3.744129e-3
GO:0048265	response to pain	3.809219e-3
GO:0031295	T cell costimulation	3.916358e-3
GO:0070328	triglyceride homeostasis	3.937384e-3
GO:0060191	regulation of lipase activity	3.937842e-3
GO:0002475	antigen processing and presentation via MHC class Ib	3.965099e-3
GO:0051541	elastin metabolic process	3.965099e-3
GO:0043316	cytotoxic T cell degranulation	3.989333e-3
GO:0019307	mannose biosynthetic process	3.989333e-3
GO:0000917	barrier septum formation	3.989333e-3
GO:0002826	negative regulation of T-helper 1 type immune response	3.989333e-3
GO:0051583	dopamine uptake	3.990520e-3
GO:0009185	ribonucleoside diphosphate metabolic process	4.008061e-3
GO:0042574	retinal metabolic process	4.016988e-3
GO:0042770	signal transduction in response to DNA damage	4.025573e-3
GO:0009620	response to fungus	4.028535e-3
GO:0040007	growth	4.056481e-3
GO:0045654	positive regulation of megakaryocyte differentiation	4.081731e-3
GO:0043056	forward locomotion	4.158882e-3
GO:0046881	positive regulation of follicle-stimulating hormone secretion	4.186734e-3
GO:0042245	RNA repair	4.186734e-3
GO:0009913	epidermal cell differentiation	4.230154e-3
GO:0002682	regulation of immune system process	4.276719e-3
GO:0050715	positive regulation of cytokine secretion	4.284617e-3
GO:0044243	multicellular organismal catabolic process	4.302847e-3
GO:0030421	defecation	4.342059e-3
GO:0070845	polyubiquitinated misfolded protein transport	4.342059e-3
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	4.342059e-3
GO:2000304	positive regulation of ceramide biosynthetic process	4.363185e-3
GO:0035814	negative regulation of renal sodium excretion	4.364390e-3
GO:0051788	response to misfolded protein	4.395055e-3
GO:0050996	positive regulation of lipid catabolic process	4.458382e-3
GO:0009190	cyclic nucleotide biosynthetic process	4.489634e-3
GO:0034220	ion transmembrane transport	4.496894e-3
GO:0030239	myofibril assembly	4.500728e-3
GO:0055014	atrial cardiac muscle cell development	4.532976e-3
GO:0006171	cAMP biosynthetic process	4.556941e-3
GO:0001504	neurotransmitter uptake	4.556941e-3
GO:0006811	ion transport	4.594181e-3
GO:0060710	chorio-allantoic fusion	4.595923e-3
GO:0010898	positive regulation of triglyceride catabolic process	4.602928e-3
GO:0051029	rRNA transport	4.621029e-3
GO:0035455	response to interferon-alpha	4.621029e-3
GO:0032205	negative regulation of telomere maintenance	4.621029e-3
GO:0042255	ribosome assembly	4.678244e-3
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway	4.679755e-3
GO:0051336	regulation of hydrolase activity	4.685364e-3
GO:0014034	neural crest cell fate commitment	4.716900e-3
GO:0006307	DNA dealkylation involved in DNA repair	4.722221e-3
GO:0032689	negative regulation of interferon-gamma production	4.724733e-3
GO:0035750	protein localization to myelin sheath abaxonal region	4.752002e-3
GO:2000781	positive regulation of double-strand break repair	4.752002e-3
GO:0034241	positive regulation of macrophage fusion	4.752002e-3
GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	4.752002e-3
GO:0015966	diadenosine tetraphosphate biosynthetic process	4.752002e-3
GO:0031468	nuclear envelope reassembly	4.752002e-3
GO:0010996	response to auditory stimulus	4.752002e-3
GO:0060644	mammary gland epithelial cell differentiation	4.833144e-3
GO:0007214	gamma-aminobutyric acid signaling pathway	4.888154e-3
GO:0003091	renal water homeostasis	4.894761e-3
GO:0001570	vasculogenesis	4.957340e-3
GO:0009636	response to toxin	5.005177e-3
GO:0002253	activation of immune response	5.007391e-3
GO:0051246	regulation of protein metabolic process	5.034663e-3
GO:0015840	urea transport	5.108453e-3
GO:0002309	T cell proliferation involved in immune response	5.108453e-3
GO:0045987	positive regulation of smooth muscle contraction	5.112302e-3
GO:0006106	fumarate metabolic process	5.114658e-3
GO:0051937	catecholamine transport	5.147878e-3
GO:0010863	positive regulation of phospholipase C activity	5.207767e-3
GO:0035510	DNA dealkylation	5.259834e-3
GO:0033240	positive regulation of cellular amine metabolic process	5.259834e-3
GO:0051856	adhesion to symbiont	5.315423e-3
GO:0052572	response to host immune response	5.382014e-3
GO:0042402	cellular biogenic amine catabolic process	5.456545e-3
GO:0042110	T cell activation	5.457381e-3
GO:0007199	G-protein signaling, coupled to cGMP nucleotide second messenger	5.458541e-3
GO:0043001	Golgi to plasma membrane protein transport	5.468297e-3
GO:0030819	positive regulation of cAMP biosynthetic process	5.506674e-3
GO:0051549	positive regulation of keratinocyte migration	5.542484e-3
GO:0051180	vitamin transport	5.648370e-3
GO:0007618	mating	5.675197e-3
GO:0000070	mitotic sister chromatid segregation	5.675197e-3
GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	5.717811e-3
GO:0061162	establishment of monopolar cell polarity	5.748863e-3
GO:0051917	regulation of fibrinolysis	5.840365e-3
GO:0032713	negative regulation of interleukin-4 production	5.840365e-3
GO:0022607	cellular component assembly	5.923237e-3
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	5.926576e-3
GO:0048841	regulation of axon extension involved in axon guidance	5.927891e-3
GO:0007016	cytoskeletal anchoring at plasma membrane	6.065658e-3
GO:0006518	peptide metabolic process	6.093876e-3
GO:0002709	regulation of T cell mediated immunity	6.197134e-3
GO:0030382	sperm mitochondrion organization	6.308646e-3
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway	6.326040e-3
GO:0034765	regulation of ion transmembrane transport	6.353064e-3
GO:0032892	positive regulation of organic acid transport	6.388014e-3
GO:0043500	muscle adaptation	6.456099e-3
GO:0050877	neurological system process	6.490465e-3
GO:0046960	sensitization	6.492091e-3
GO:0042664	negative regulation of endodermal cell fate specification	6.492091e-3
GO:0071827	plasma lipoprotein particle organization	6.492166e-3
GO:0009725	response to hormone stimulus	6.510453e-3
GO:0050728	negative regulation of inflammatory response	6.662571e-3
GO:0030193	regulation of blood coagulation	6.756403e-3
GO:0070535	histone H2A K63-linked ubiquitination	6.815441e-3
GO:0021881	Wnt receptor signaling pathway involved in forebrain neuron fate commitment	6.815441e-3
GO:0015850	organic alcohol transport	6.819049e-3
GO:0008617	guanosine metabolic process	6.826729e-3
GO:0043154	negative regulation of caspase activity	6.827012e-3
GO:0006140	regulation of nucleotide metabolic process	6.906669e-3
GO:0051262	protein tetramerization	6.908870e-3
GO:0045078	positive regulation of interferon-gamma biosynthetic process	6.972500e-3
GO:0070234	positive regulation of T cell apoptosis	6.992862e-3
GO:0031032	actomyosin structure organization	7.102826e-3
GO:0060973	cell migration involved in heart development	7.131999e-3
GO:0042730	fibrinolysis	7.131999e-3
GO:0042339	keratan sulfate metabolic process	7.151992e-3
GO:2000334	positive regulation of blood microparticle formation	7.151992e-3
GO:0007172	signal complex assembly	7.151992e-3
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	7.153085e-3
GO:0051257	spindle midzone assembly involved in meiosis	7.167376e-3
GO:0015959	diadenosine polyphosphate metabolic process	7.167376e-3
GO:0002768	immune response-regulating cell surface receptor signaling pathway	7.174598e-3
GO:0007190	activation of adenylate cyclase activity	7.178775e-3
GO:0030855	epithelial cell differentiation	7.183394e-3
GO:0009134	nucleoside diphosphate catabolic process	7.351583e-3
GO:0043085	positive regulation of catalytic activity	7.384431e-3
GO:0007320	insemination	7.417963e-3
GO:0001954	positive regulation of cell-matrix adhesion	7.426335e-3
GO:0050829	defense response to Gram-negative bacterium	7.457986e-3
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	7.459265e-3
GO:0019098	reproductive behavior	7.469267e-3
GO:0002329	pre-B cell differentiation	7.560819e-3
GO:0065005	protein-lipid complex assembly	7.631688e-3
GO:0043503	skeletal muscle fiber adaptation	7.644525e-3
GO:0050727	regulation of inflammatory response	7.658845e-3
GO:0010634	positive regulation of epithelial cell migration	7.689038e-3
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	7.700538e-3
GO:0070207	protein homotrimerization	7.700538e-3
GO:0006826	iron ion transport	7.752787e-3
GO:0048002	antigen processing and presentation of peptide antigen	7.769036e-3
GO:0035270	endocrine system development	7.828198e-3
GO:0070243	regulation of thymocyte apoptosis	7.877828e-3
GO:0044093	positive regulation of molecular function	7.896641e-3
GO:0035690	cellular response to drug	7.902046e-3
GO:0031124	mRNA 3'-end processing	7.940927e-3
GO:0006914	autophagy	7.976006e-3
GO:0002455	humoral immune response mediated by circulating immunoglobulin	8.005055e-3
GO:0061042	vascular wound healing	8.089664e-3
GO:0031275	regulation of lateral pseudopodium assembly	8.089664e-3
GO:0018960	4-nitrophenol metabolic process	8.089664e-3
GO:0019413	acetate biosynthetic process	8.089664e-3
GO:0019542	propionate biosynthetic process	8.089664e-3
GO:0000819	sister chromatid segregation	8.089995e-3
GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib	8.136352e-3
GO:0043558	regulation of translational initiation in response to stress	8.136352e-3
GO:0006282	regulation of DNA repair	8.166483e-3
GO:0048640	negative regulation of developmental growth	8.176679e-3
GO:0021502	neural fold elevation formation	8.190345e-3
GO:0090026	positive regulation of monocyte chemotaxis	8.202684e-3
GO:0009113	purine base biosynthetic process	8.202684e-3
GO:0046165	alcohol biosynthetic process	8.275483e-3
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	8.304336e-3
GO:0070925	organelle assembly	8.400436e-3
GO:0007620	copulation	8.519820e-3