Novel motif:108

name:	motif108_AACKSARM

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0018874	benzoate metabolic process	2.933810e-9
GO:0010389	regulation of G2/M transition of mitotic cell cycle	8.425299e-9
GO:0043922	negative regulation by host of viral transcription	8.436142e-9
GO:0043420	anthranilate metabolic process	8.857040e-9
GO:0034516	response to vitamin B6	8.857040e-9
GO:0019442	tryptophan catabolic process to acetyl-CoA	3.170047e-8
GO:0032516	positive regulation of phosphoprotein phosphatase activity	8.848837e-8
GO:0065004	protein-DNA complex assembly	1.123132e-7
GO:0032897	negative regulation of viral transcription	2.068598e-7
GO:0051383	kinetochore organization	4.008417e-7
GO:0051573	negative regulation of histone H3-K9 methylation	4.115481e-7
GO:0034014	response to triglyceride	4.727942e-7
GO:0035404	histone-serine phosphorylation	6.836239e-7
GO:0034080	CenH3-containing nucleosome assembly at centromere	1.338122e-6
GO:0031572	G2/M transition DNA damage checkpoint	1.385736e-6
GO:0019805	quinolinate biosynthetic process	1.639689e-6
GO:0031576	G2/M transition checkpoint	2.234388e-6
GO:0051004	regulation of lipoprotein lipase activity	2.248789e-6
GO:0006335	DNA replication-dependent nucleosome assembly	2.277698e-6
GO:0046874	quinolinate metabolic process	2.386502e-6
GO:0071824	protein-DNA complex subunit organization	2.965787e-6
GO:0031055	chromatin remodeling at centromere	3.241507e-6
GO:0007249	I-kappaB kinase/NF-kappaB cascade	3.273155e-6
GO:2000121	regulation of removal of superoxide radicals	4.554568e-6
GO:0072337	modified amino acid transport	4.591976e-6
GO:0051534	negative regulation of NFAT protein import into nucleus	5.152124e-6
GO:0033194	response to hydroperoxide	5.153371e-6
GO:0030683	evasion by virus of host immune response	5.313297e-6
GO:0046687	response to chromate	5.370607e-6
GO:0033986	response to methanol	5.370607e-6
GO:2000648	positive regulation of stem cell proliferation	6.774613e-6
GO:0000079	regulation of cyclin-dependent protein kinase activity	7.193655e-6
GO:0016572	histone phosphorylation	7.914492e-6
GO:0051382	kinetochore assembly	8.851685e-6
GO:0071780	mitotic cell cycle G2/M transition checkpoint	9.785088e-6
GO:0034470	ncRNA processing	1.040706e-5
GO:0007095	mitotic cell cycle G2/M transition DNA damage checkpoint	1.045255e-5
GO:0006214	thymidine catabolic process	1.104801e-5
GO:0046104	thymidine metabolic process	1.189663e-5
GO:0085020	protein K6-linked ubiquitination	1.893656e-5
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.918426e-5
GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining	2.211952e-5
GO:2000685	positive regulation of cellular response to X-ray	2.211952e-5
GO:2001038	regulation of cellular response to drug	2.211952e-5
GO:0003131	mesodermal-endodermal cell signaling	2.211952e-5
GO:0031052	chromosome breakage	2.211952e-5
GO:0035978	histone H2A-S139 phosphorylation	2.211952e-5
GO:2000602	regulation of interphase of mitotic cell cycle	2.265959e-5
GO:0034723	DNA replication-dependent nucleosome organization	2.688059e-5
GO:0006145	purine base catabolic process	2.723792e-5
GO:0090130	tissue migration	2.972133e-5
GO:0001832	blastocyst growth	3.263281e-5
GO:0043486	histone exchange	3.283975e-5
GO:0090322	regulation of superoxide metabolic process	3.732282e-5
GO:0006212	uracil catabolic process	3.738746e-5
GO:0006210	thymine catabolic process	3.738746e-5
GO:0021528	commissural neuron differentiation in spinal cord	3.991160e-5
GO:2000779	regulation of double-strand break repair	4.018974e-5
GO:0033566	gamma-tubulin complex localization	4.070774e-5
GO:0051707	response to other organism	4.123590e-5
GO:0046339	diacylglycerol metabolic process	4.379527e-5
GO:0031497	chromatin assembly	4.489429e-5
GO:0008033	tRNA processing	5.286553e-5
GO:0051532	regulation of NFAT protein import into nucleus	5.354404e-5
GO:0010989	negative regulation of low-density lipoprotein particle clearance	6.063833e-5
GO:0046426	negative regulation of JAK-STAT cascade	6.228633e-5
GO:0043921	modulation by host of viral transcription	6.266524e-5
GO:0006367	transcription initiation from RNA polymerase II promoter	6.357789e-5
GO:0035026	leading edge cell differentiation	7.578461e-5
GO:0045872	positive regulation of rhodopsin gene expression	8.312482e-5
GO:0034340	response to type I interferon	8.957001e-5
GO:0060443	mammary gland morphogenesis	9.376430e-5
GO:0060337	type I interferon-mediated signaling pathway	9.760131e-5
GO:0035307	positive regulation of protein dephosphorylation	9.933710e-5
GO:0006366	transcription from RNA polymerase II promoter	9.995561e-5
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.019639e-4
GO:0035988	chondrocyte proliferation	1.044890e-4
GO:0009449	gamma-aminobutyric acid biosynthetic process	1.073169e-4
GO:0043044	ATP-dependent chromatin remodeling	1.102874e-4
GO:0002551	mast cell chemotaxis	1.123197e-4
GO:0048662	negative regulation of smooth muscle cell proliferation	1.128596e-4
GO:0010631	epithelial cell migration	1.138323e-4
GO:0010713	negative regulation of collagen metabolic process	1.218540e-4
GO:0010288	response to lead ion	1.249399e-4
GO:0009607	response to biotic stimulus	1.283059e-4
GO:0046951	ketone body biosynthetic process	1.386311e-4
GO:0019859	thymine metabolic process	1.386311e-4
GO:0051089	constitutive protein ectodomain proteolysis	1.400601e-4
GO:0033617	mitochondrial respiratory chain complex IV assembly	1.400601e-4
GO:0034660	ncRNA metabolic process	1.414174e-4
GO:0010811	positive regulation of cell-substrate adhesion	1.442325e-4
GO:0034508	centromere complex assembly	1.481582e-4
GO:0000279	M phase	1.485812e-4
GO:0050955	thermoception	1.494717e-4
GO:0010988	regulation of low-density lipoprotein particle clearance	1.545782e-4
GO:0090304	nucleic acid metabolic process	1.546563e-4
GO:0034088	maintenance of mitotic sister chromatid cohesion	1.552959e-4
GO:0035306	positive regulation of dephosphorylation	1.561589e-4
GO:0042306	regulation of protein import into nucleus	1.675816e-4
GO:0034377	plasma lipoprotein particle assembly	1.698680e-4
GO:0006333	chromatin assembly or disassembly	1.811975e-4
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	1.846651e-4
GO:0035518	histone H2A monoubiquitination	1.848125e-4
GO:0033522	histone H2A ubiquitination	1.889918e-4
GO:0042633	hair cycle	1.923543e-4
GO:0006689	ganglioside catabolic process	1.988271e-4
GO:0016180	snRNA processing	2.011508e-4
GO:0060312	regulation of blood vessel remodeling	2.020293e-4
GO:0051365	cellular response to potassium ion starvation	2.020293e-4
GO:0009615	response to virus	2.041530e-4
GO:0006207	'de novo' pyrimidine base biosynthetic process	2.072356e-4
GO:0046716	muscle cell homeostasis	2.161700e-4
GO:0045116	protein neddylation	2.170631e-4
GO:0035304	regulation of protein dephosphorylation	2.250967e-4
GO:0046125	pyrimidine deoxyribonucleoside metabolic process	2.303816e-4
GO:2000620	positive regulation of histone H4-K16 acetylation	2.355850e-4
GO:0070512	positive regulation of histone H4-K20 methylation	2.355850e-4
GO:2000617	positive regulation of histone H3-K9 acetylation	2.355850e-4
GO:0090402	oncogene-induced senescence	2.400947e-4
GO:0071156	regulation of cell cycle arrest	2.456925e-4
GO:0007064	mitotic sister chromatid cohesion	2.519437e-4
GO:0006352	transcription initiation, DNA-dependent	2.543264e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	2.549981e-4
GO:0030212	hyaluronan metabolic process	2.611998e-4
GO:0045199	maintenance of epithelial cell apical/basal polarity	2.660589e-4
GO:0006334	nucleosome assembly	2.703358e-4
GO:0006638	neutral lipid metabolic process	2.705084e-4
GO:0008202	steroid metabolic process	2.711524e-4
GO:0016070	RNA metabolic process	2.735693e-4
GO:0044088	regulation of vacuole organization	2.806790e-4
GO:0032288	myelin assembly	2.926565e-4
GO:2000786	positive regulation of autophagic vacuole assembly	3.124263e-4
GO:0050916	sensory perception of sweet taste	3.228819e-4
GO:0090230	regulation of centromere complex assembly	3.228819e-4
GO:2000036	regulation of stem cell maintenance	3.258911e-4
GO:0072091	regulation of stem cell proliferation	3.389884e-4
GO:0045869	negative regulation of retroviral genome replication	3.409651e-4
GO:0045608	negative regulation of auditory receptor cell differentiation	3.436060e-4
GO:0045046	protein import into peroxisome membrane	3.442698e-4
GO:0010467	gene expression	3.486141e-4
GO:0046822	regulation of nucleocytoplasmic transport	3.544222e-4
GO:0035441	cell migration involved in vasculogenesis	3.577138e-4
GO:0034589	hydroxyproline transport	3.577138e-4
GO:0015826	threonine transport	3.577138e-4
GO:0015911	plasma membrane long-chain fatty acid transport	3.718895e-4
GO:0010624	regulation of Schwann cell proliferation	3.725558e-4
GO:0042159	lipoprotein catabolic process	3.853727e-4
GO:0006639	acylglycerol metabolic process	3.917214e-4
GO:0050672	negative regulation of lymphocyte proliferation	3.972415e-4
GO:0070664	negative regulation of leukocyte proliferation	4.000736e-4
GO:0016073	snRNA metabolic process	4.007534e-4
GO:0000080	G1 phase of mitotic cell cycle	4.061111e-4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	4.141553e-4
GO:0034381	plasma lipoprotein particle clearance	4.149761e-4
GO:0071930	negative regulation of transcription involved in G1/S phase of mitotic cell cycle	4.166889e-4
GO:0055088	lipid homeostasis	4.201633e-4
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	4.250558e-4
GO:0015804	neutral amino acid transport	4.280019e-4
GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	4.404087e-4
GO:0010886	positive regulation of cholesterol storage	4.478251e-4
GO:0042990	regulation of transcription factor import into nucleus	4.523439e-4
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	4.708361e-4
GO:0030423	targeting of mRNA for destruction involved in RNA interference	4.750032e-4
GO:0045738	negative regulation of DNA repair	4.768871e-4
GO:0051318	G1 phase	4.876840e-4
GO:0072526	pyridine-containing compound catabolic process	4.882275e-4
GO:0032290	peripheral nervous system myelin formation	4.882275e-4
GO:0071335	hair follicle cell proliferation	4.882275e-4
GO:0042632	cholesterol homeostasis	4.898162e-4
GO:0016557	peroxisome membrane biogenesis	5.216027e-4
GO:0043129	surfactant homeostasis	5.226146e-4
GO:0016598	protein arginylation	5.237858e-4
GO:0030518	steroid hormone receptor signaling pathway	5.371348e-4
GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	5.376775e-4
GO:0043526	neuroprotection	5.431856e-4
GO:0034379	very-low-density lipoprotein particle assembly	5.534464e-4
GO:0031054	pre-miRNA processing	5.827677e-4
GO:0006493	protein O-linked glycosylation	5.835018e-4
GO:0006651	diacylglycerol biosynthetic process	5.909100e-4
GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein	5.965422e-4
GO:0031134	sister chromatid biorientation	6.025557e-4
GO:0000212	meiotic spindle organization	6.093097e-4
GO:0010719	negative regulation of epithelial to mesenchymal transition	6.128995e-4
GO:0034754	cellular hormone metabolic process	6.136849e-4
GO:0001942	hair follicle development	6.291455e-4
GO:0002262	myeloid cell homeostasis	6.308694e-4
GO:0010721	negative regulation of cell development	6.326767e-4
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	6.347294e-4
GO:0007638	mechanosensory behavior	6.694407e-4
GO:0000075	cell cycle checkpoint	7.047567e-4
GO:0001893	maternal placenta development	7.257660e-4
GO:0045607	regulation of auditory receptor cell differentiation	7.335037e-4
GO:0032486	Rap protein signal transduction	7.335037e-4
GO:0051704	multi-organism process	7.469478e-4
GO:0045069	regulation of viral genome replication	7.500428e-4
GO:0071447	cellular response to hydroperoxide	7.719318e-4
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	8.217563e-4
GO:0000236	mitotic prometaphase	8.474302e-4
GO:0097045	phosphatidylserine exposure on blood platelet	8.540515e-4
GO:0071670	smooth muscle cell chemotaxis	8.540515e-4
GO:0060981	cell migration involved in coronary angiogenesis	8.540515e-4
GO:0043170	macromolecule metabolic process	8.631258e-4
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	8.841799e-4
GO:0032814	regulation of natural killer cell activation	9.082463e-4
GO:0009435	NAD biosynthetic process	9.121431e-4
GO:0043666	regulation of phosphoprotein phosphatase activity	9.206719e-4
GO:0030889	negative regulation of B cell proliferation	9.274277e-4
GO:0051320	S phase	9.490032e-4
GO:0008152	metabolic process	9.775281e-4
GO:0051403	stress-activated MAPK cascade	1.018769e-3
GO:0007565	female pregnancy	1.057960e-3
GO:2000772	regulation of cellular senescence	1.076197e-3
GO:0060253	negative regulation of glial cell proliferation	1.088545e-3
GO:0007093	mitotic cell cycle checkpoint	1.089902e-3
GO:0046683	response to organophosphorus	1.094895e-3
GO:0032496	response to lipopolysaccharide	1.107708e-3
GO:0015825	L-serine transport	1.117843e-3
GO:0006084	acetyl-CoA metabolic process	1.118125e-3
GO:0002384	hepatic immune response	1.121551e-3
GO:0022403	cell cycle phase	1.130593e-3
GO:0046112	nucleobase biosynthetic process	1.188040e-3
GO:0007250	activation of NF-kappaB-inducing kinase activity	1.242019e-3
GO:0071402	cellular response to lipoprotein particle stimulus	1.277082e-3
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	1.287552e-3
GO:0032581	ER-dependent peroxisome organization	1.314930e-3
GO:0035572	N-terminal peptidyl-serine dimethylation	1.332885e-3
GO:0035573	N-terminal peptidyl-serine trimethylation	1.332885e-3
GO:0018016	N-terminal peptidyl-proline dimethylation	1.332885e-3
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.332885e-3
GO:0060968	regulation of gene silencing	1.428211e-3
GO:0003017	lymph circulation	1.450245e-3
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	1.467773e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	1.468635e-3
GO:0071221	cellular response to bacterial lipopeptide	1.472937e-3
GO:0033157	regulation of intracellular protein transport	1.487764e-3
GO:0018209	peptidyl-serine modification	1.503845e-3
GO:0008636	activation of caspase activity by protein phosphorylation	1.531181e-3
GO:0035409	histone H3-Y41 phosphorylation	1.531181e-3
GO:0006313	transposition, DNA-mediated	1.531181e-3
GO:2000334	positive regulation of blood microparticle formation	1.533593e-3
GO:0032966	negative regulation of collagen biosynthetic process	1.593349e-3
GO:0060251	regulation of glial cell proliferation	1.595662e-3
GO:0044111	development involved in symbiotic interaction	1.595946e-3
GO:0019089	transmission of virus	1.595946e-3
GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	1.595946e-3
GO:0006662	glycerol ether metabolic process	1.612674e-3
GO:0043523	regulation of neuron apoptosis	1.621399e-3
GO:0042976	activation of Janus kinase activity	1.640928e-3
GO:0035117	embryonic arm morphogenesis	1.647233e-3
GO:0042594	response to starvation	1.675493e-3
GO:0006139	nucleobase-containing compound metabolic process	1.712919e-3
GO:0071479	cellular response to ionizing radiation	1.729305e-3
GO:0031507	heterochromatin formation	1.744446e-3
GO:0035644	phosphoanandamide dephosphorylation	1.751830e-3
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.751830e-3
GO:0007113	endomitotic cell cycle	1.751830e-3
GO:0001519	peptide amidation	1.751830e-3
GO:2001022	positive regulation of response to DNA damage stimulus	1.779134e-3
GO:0002237	response to molecule of bacterial origin	1.799498e-3
GO:0048681	negative regulation of axon regeneration	1.865186e-3
GO:0042997	negative regulation of Golgi to plasma membrane protein transport	1.876563e-3
GO:0042538	hyperosmotic salinity response	1.876563e-3
GO:0060977	coronary vasculature morphogenesis	1.883223e-3
GO:0034629	cellular protein complex localization	1.885512e-3
GO:0018105	peptidyl-serine phosphorylation	1.892841e-3
GO:0042308	negative regulation of protein import into nucleus	1.904181e-3
GO:0035308	negative regulation of protein dephosphorylation	1.939486e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	1.939486e-3
GO:0031223	auditory behavior	1.985258e-3
GO:0042992	negative regulation of transcription factor import into nucleus	2.002045e-3
GO:0014070	response to organic cyclic compound	2.023288e-3
GO:0030522	intracellular receptor mediated signaling pathway	2.040161e-3
GO:0019359	nicotinamide nucleotide biosynthetic process	2.063828e-3
GO:0002740	negative regulation of cytokine secretion involved in immune response	2.099233e-3
GO:0051851	modification by host of symbiont morphology or physiology	2.108682e-3
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.125576e-3
GO:0070173	regulation of enamel mineralization	2.125576e-3
GO:0010897	negative regulation of triglyceride catabolic process	2.125576e-3
GO:0001833	inner cell mass cell proliferation	2.132172e-3
GO:0006537	glutamate biosynthetic process	2.153095e-3
GO:0006399	tRNA metabolic process	2.209662e-3
GO:0070534	protein K63-linked ubiquitination	2.280786e-3
GO:0055096	low-density lipoprotein particle mediated signaling	2.284914e-3
GO:0007468	regulation of rhodopsin gene expression	2.289124e-3
GO:0034341	response to interferon-gamma	2.303994e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	2.315004e-3
GO:0035090	maintenance of apical/basal cell polarity	2.317035e-3
GO:0060575	intestinal epithelial cell differentiation	2.327068e-3
GO:0006742	NADP catabolic process	2.394274e-3
GO:0006914	autophagy	2.480450e-3
GO:0006642	triglyceride mobilization	2.498112e-3
GO:0046121	deoxyribonucleoside catabolic process	2.506296e-3
GO:2000242	negative regulation of reproductive process	2.526543e-3
GO:0001780	neutrophil homeostasis	2.563826e-3
GO:0015824	proline transport	2.581967e-3
GO:0042977	activation of JAK2 kinase activity	2.590650e-3
GO:0030174	regulation of DNA-dependent DNA replication initiation	2.623155e-3
GO:0048263	determination of dorsal identity	2.623155e-3
GO:0022002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway	2.623155e-3
GO:2000774	positive regulation of cellular senescence	2.642910e-3
GO:0035986	senescence-associated heterochromatin focus formation	2.642910e-3
GO:0050702	interleukin-1 beta secretion	2.642910e-3
GO:0032386	regulation of intracellular transport	2.653251e-3
GO:0006396	RNA processing	2.671764e-3
GO:0015031	protein transport	2.710966e-3
GO:0042694	muscle cell fate specification	2.769026e-3
GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	2.789431e-3
GO:0034383	low-density lipoprotein particle clearance	2.810939e-3
GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	2.835080e-3
GO:0060876	semicircular canal formation	2.887086e-3
GO:0006189	'de novo' IMP biosynthetic process	2.887086e-3
GO:2000773	negative regulation of cellular senescence	2.906455e-3
GO:0043697	cell dedifferentiation	2.906455e-3
GO:0097006	regulation of plasma lipoprotein particle levels	2.927451e-3
GO:0014002	astrocyte development	2.993763e-3
GO:0050951	sensory perception of temperature stimulus	3.024479e-3
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	3.024479e-3
GO:0014037	Schwann cell differentiation	3.064700e-3
GO:0035881	amacrine cell differentiation	3.069668e-3
GO:0010626	negative regulation of Schwann cell proliferation	3.107089e-3
GO:0008203	cholesterol metabolic process	3.150783e-3
GO:0048285	organelle fission	3.266318e-3
GO:0005976	polysaccharide metabolic process	3.275730e-3
GO:0071481	cellular response to X-ray	3.358202e-3
GO:0060100	positive regulation of phagocytosis, engulfment	3.358202e-3
GO:0034619	cellular chaperone-mediated protein complex assembly	3.420472e-3
GO:0015807	L-amino acid transport	3.467996e-3
GO:0032651	regulation of interleukin-1 beta production	3.505485e-3
GO:0046950	cellular ketone body metabolic process	3.516579e-3
GO:0071459	protein localization to chromosome, centromeric region	3.604821e-3
GO:0042908	xenobiotic transport	3.604821e-3
GO:0051702	interaction with symbiont	3.635335e-3
GO:0050901	leukocyte tethering or rolling	3.678988e-3
GO:0060659	nipple sheath formation	3.720155e-3
GO:0060649	mammary gland bud elongation	3.720155e-3
GO:0018023	peptidyl-lysine trimethylation	3.720155e-3
GO:0021933	radial glia guided migration of cerebellar granule cell	3.734749e-3
GO:0090209	negative regulation of triglyceride metabolic process	3.737312e-3
GO:0045017	glycerolipid biosynthetic process	3.765840e-3
GO:0006222	UMP biosynthetic process	3.767749e-3
GO:0031623	receptor internalization	3.778193e-3
GO:0050847	progesterone receptor signaling pathway	3.799582e-3
GO:0005981	regulation of glycogen catabolic process	3.799582e-3
GO:2000077	negative regulation of type B pancreatic cell development	3.845229e-3
GO:0045059	positive thymic T cell selection	3.899605e-3
GO:0019695	choline metabolic process	3.915871e-3
GO:0051412	response to corticosterone stimulus	3.920429e-3
GO:0002739	regulation of cytokine secretion involved in immune response	3.968282e-3
GO:0006807	nitrogen compound metabolic process	3.990026e-3
GO:0043622	cortical microtubule organization	3.997508e-3
GO:0030103	vasopressin secretion	3.997508e-3
GO:0034728	nucleosome organization	4.012137e-3
GO:0055069	zinc ion homeostasis	4.027433e-3
GO:0006898	receptor-mediated endocytosis	4.079455e-3
GO:0019441	tryptophan catabolic process to kynurenine	4.080248e-3
GO:0043950	positive regulation of cAMP-mediated signaling	4.082301e-3
GO:0046600	negative regulation of centriole replication	4.082301e-3
GO:0045655	regulation of monocyte differentiation	4.092335e-3
GO:0046464	acylglycerol catabolic process	4.141027e-3
GO:0060056	mammary gland involution	4.142822e-3
GO:0032488	Cdc42 protein signal transduction	4.143079e-3
GO:0014044	Schwann cell development	4.184335e-3
GO:0042953	lipoprotein transport	4.207887e-3
GO:0045204	MAPK export from nucleus	4.254044e-3
GO:0045209	MAPK phosphatase export from nucleus, leptomycin B sensitive	4.254044e-3
GO:0007263	nitric oxide mediated signal transduction	4.264962e-3
GO:0006513	protein monoubiquitination	4.306504e-3
GO:0090311	regulation of protein deacetylation	4.331981e-3
GO:0015871	choline transport	4.381866e-3
GO:0043949	regulation of cAMP-mediated signaling	4.386657e-3
GO:0042512	negative regulation of tyrosine phosphorylation of Stat1 protein	4.395926e-3
GO:0021955	central nervous system neuron axonogenesis	4.438095e-3
GO:0042036	negative regulation of cytokine biosynthetic process	4.514072e-3
GO:0060022	hard palate development	4.543806e-3
GO:0006310	DNA recombination	4.604588e-3
GO:0000725	recombinational repair	4.684660e-3
GO:0044260	cellular macromolecule metabolic process	4.693992e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	4.698650e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	4.698650e-3
GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein	4.698650e-3
GO:0043308	eosinophil degranulation	4.730026e-3
GO:0009239	enterobactin biosynthetic process	4.730026e-3
GO:0032802	low-density lipoprotein particle receptor catabolic process	4.730026e-3
GO:0045088	regulation of innate immune response	4.742712e-3
GO:0032774	RNA biosynthetic process	4.839704e-3
GO:0008380	RNA splicing	4.878567e-3
GO:0032925	regulation of activin receptor signaling pathway	4.885375e-3
GO:0019433	triglyceride catabolic process	4.927984e-3
GO:0048203	vesicle targeting, trans-Golgi to endosome	5.031242e-3
GO:0045355	negative regulation of interferon-alpha biosynthetic process	5.031242e-3
GO:0046358	butyrate biosynthetic process	5.031242e-3
GO:0070563	negative regulation of vitamin D receptor signaling pathway	5.039337e-3
GO:0050968	detection of chemical stimulus involved in sensory perception of pain	5.039337e-3
GO:0035921	desmosome disassembly	5.039337e-3
GO:0032782	bile acid secretion	5.039337e-3
GO:0006351	transcription, DNA-dependent	5.089452e-3
GO:0048853	forebrain morphogenesis	5.096955e-3
GO:0070375	BMK cascade	5.144391e-3
GO:0022402	cell cycle process	5.177011e-3
GO:0060409	positive regulation of acetylcholine metabolic process	5.257125e-3
GO:0071379	cellular response to prostaglandin stimulus	5.281209e-3
GO:0006014	D-ribose metabolic process	5.281209e-3
GO:0002331	pre-B cell allelic exclusion	5.290017e-3
GO:0015760	glucose-6-phosphate transport	5.291222e-3
GO:0006536	glutamate metabolic process	5.292659e-3
GO:0006953	acute-phase response	5.389830e-3
GO:0010390	histone monoubiquitination	5.470125e-3
GO:0032816	positive regulation of natural killer cell activation	5.678709e-3
GO:0009074	aromatic amino acid family catabolic process	5.692973e-3
GO:0006306	DNA methylation	5.726455e-3
GO:0051790	short-chain fatty acid biosynthetic process	5.786159e-3
GO:0006668	sphinganine-1-phosphate metabolic process	5.786159e-3
GO:0044238	primary metabolic process	5.833158e-3
GO:0043112	receptor metabolic process	5.910496e-3
GO:0046519	sphingoid metabolic process	5.932382e-3
GO:0034134	toll-like receptor 2 signaling pathway	5.980784e-3
GO:0034130	toll-like receptor 1 signaling pathway	5.980784e-3
GO:0032731	positive regulation of interleukin-1 beta production	6.059658e-3
GO:0051301	cell division	6.077578e-3
GO:0060333	interferon-gamma-mediated signaling pathway	6.110270e-3
GO:0035305	negative regulation of dephosphorylation	6.128168e-3
GO:0071305	cellular response to vitamin D	6.129717e-3
GO:0032329	serine transport	6.185842e-3
GO:0043181	vacuolar sequestering	6.242835e-3
GO:0000023	maltose metabolic process	6.242835e-3
GO:0005985	sucrose metabolic process	6.242835e-3
GO:0009629	response to gravity	6.279069e-3
GO:0031958	corticosteroid receptor signaling pathway	6.304183e-3
GO:0031639	plasminogen activation	6.357867e-3
GO:0010070	zygote asymmetric cell division	6.477682e-3
GO:0033700	phospholipid efflux	6.522361e-3
GO:0050710	negative regulation of cytokine secretion	6.548097e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	6.579732e-3
GO:0034097	response to cytokine stimulus	6.616780e-3
GO:0021516	dorsal spinal cord development	6.641673e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	6.695324e-3
GO:0051386	regulation of nerve growth factor receptor signaling pathway	6.720802e-3
GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	6.775074e-3
GO:0001661	conditioned taste aversion	6.775074e-3
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	6.811766e-3
GO:0061015	snRNA import into nucleus	6.827390e-3
GO:0050973	detection of mechanical stimulus involved in equilibrioception	6.827390e-3
GO:0006430	lysyl-tRNA aminoacylation	6.827390e-3
GO:0045645	positive regulation of eosinophil differentiation	6.827390e-3
GO:0048822	enucleate erythrocyte development	6.827390e-3
GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	6.875012e-3
GO:2000366	positive regulation of STAT protein import into nucleus	6.948102e-3
GO:0070091	glucagon secretion	6.948102e-3
GO:0051385	response to mineralocorticoid stimulus	7.053680e-3
GO:0048820	hair follicle maturation	7.074015e-3
GO:0060311	negative regulation of elastin catabolic process	7.078883e-3
GO:0060313	negative regulation of blood vessel remodeling	7.078883e-3
GO:0010711	negative regulation of collagen catabolic process	7.078883e-3
GO:0010703	negative regulation of histolysis	7.078883e-3
GO:0034382	chylomicron remnant clearance	7.164413e-3
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	7.200697e-3
GO:0046677	response to antibiotic	7.202759e-3
GO:0046599	regulation of centriole replication	7.267959e-3
GO:0060976	coronary vasculature development	7.271181e-3
GO:0032388	positive regulation of intracellular transport	7.432582e-3
GO:0050917	sensory perception of umami taste	7.443210e-3
GO:0003151	outflow tract morphogenesis	7.443228e-3
GO:0071577	zinc ion transmembrane transport	7.468839e-3
GO:0034763	negative regulation of transmembrane transport	7.498075e-3
GO:0060621	negative regulation of cholesterol import	7.507009e-3
GO:0051325	interphase	7.575036e-3
GO:0070562	regulation of vitamin D receptor signaling pathway	7.620296e-3
GO:0044237	cellular metabolic process	7.722822e-3
GO:0042640	anagen	7.723827e-3
GO:0017121	phospholipid scrambling	7.738647e-3
GO:0031063	regulation of histone deacetylation	7.829649e-3
GO:0000724	double-strand break repair via homologous recombination	7.901104e-3
GO:0002313	mature B cell differentiation involved in immune response	7.978472e-3
GO:0030521	androgen receptor signaling pathway	7.990267e-3
GO:0046898	response to cycloheximide	8.031400e-3
GO:0007406	negative regulation of neuroblast proliferation	8.128539e-3
GO:0046496	nicotinamide nucleotide metabolic process	8.210268e-3
GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly	8.217987e-3
GO:0032817	regulation of natural killer cell proliferation	8.243915e-3
GO:0045087	innate immune response	8.340929e-3
GO:0071480	cellular response to gamma radiation	8.494468e-3
GO:0046824	positive regulation of nucleocytoplasmic transport	8.508222e-3
GO:0071346	cellular response to interferon-gamma	8.584402e-3
GO:0032652	regulation of interleukin-1 production	8.623836e-3
GO:0018904	organic ether metabolic process	8.689552e-3
GO:0060395	SMAD protein signal transduction	8.713338e-3
GO:0071478	cellular response to radiation	8.878489e-3
GO:0090116	C-5 methylation of cytosine	8.886620e-3
GO:0035278	negative regulation of translation involved in gene silencing by miRNA	8.886620e-3
GO:0071407	cellular response to organic cyclic compound	8.902096e-3
GO:0006733	oxidoreduction coenzyme metabolic process	8.946194e-3
GO:0032328	alanine transport	9.070301e-3
GO:0045066	regulatory T cell differentiation	9.098235e-3
GO:0009586	rhodopsin mediated phototransduction	9.098235e-3
GO:0010885	regulation of cholesterol storage	9.116758e-3
GO:0030324	lung development	9.117359e-3
GO:0043441	acetoacetic acid biosynthetic process	9.126665e-3
GO:0021993	initiation of neural tube closure	9.126665e-3
GO:0008612	peptidyl-lysine modification to hypusine	9.222307e-3
GO:0021599	abducens nerve formation	9.244472e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0048240	sperm capacitation	4.531250e-9
GO:0046513	ceramide biosynthetic process	6.575016e-9
GO:0046709	IDP catabolic process	8.570484e-9
GO:0046032	ADP catabolic process	8.570484e-9
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	1.953914e-8
GO:0019853	L-ascorbic acid biosynthetic process	2.716981e-8
GO:0046520	sphingoid biosynthetic process	4.025664e-8
GO:0002385	mucosal immune response	1.192561e-7
GO:0006082	organic acid metabolic process	1.908089e-7
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	2.019817e-7
GO:0002251	organ or tissue specific immune response	3.087543e-7
GO:0006684	sphingomyelin metabolic process	3.160563e-7
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	3.214826e-7
GO:0044283	small molecule biosynthetic process	3.859380e-7
GO:0046394	carboxylic acid biosynthetic process	4.004641e-7
GO:0043086	negative regulation of catalytic activity	5.011923e-7
GO:0050848	regulation of calcium-mediated signaling	5.975603e-7
GO:0015876	acetyl-CoA transport	6.216385e-7
GO:0006686	sphingomyelin biosynthetic process	7.190433e-7
GO:0019852	L-ascorbic acid metabolic process	7.863680e-7
GO:0046112	nucleobase biosynthetic process	8.723722e-7
GO:0061084	negative regulation of protein refolding	9.004408e-7
GO:0006189	'de novo' IMP biosynthetic process	9.958098e-7
GO:0002227	innate immune response in mucosa	1.293118e-6
GO:0042180	cellular ketone metabolic process	1.449693e-6
GO:0009191	ribonucleoside diphosphate catabolic process	1.854604e-6
GO:0019752	carboxylic acid metabolic process	1.971726e-6
GO:0046121	deoxyribonucleoside catabolic process	2.431918e-6
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	2.522956e-6
GO:0046381	CMP-N-acetylneuraminate metabolic process	2.739584e-6
GO:0048102	autophagic cell death	3.567620e-6
GO:2000688	positive regulation of rubidium ion transmembrane transporter activity	4.670611e-6
GO:2000682	positive regulation of rubidium ion transport	4.670611e-6
GO:0035826	rubidium ion transport	4.670611e-6
GO:0051030	snRNA transport	4.942602e-6
GO:0009134	nucleoside diphosphate catabolic process	5.238284e-6
GO:0019087	transformation of host cell by virus	6.835936e-6
GO:0000279	M phase	6.941689e-6
GO:0044003	modification by symbiont of host morphology or physiology	8.227025e-6
GO:0006801	superoxide metabolic process	8.364290e-6
GO:0006916	anti-apoptosis	8.412712e-6
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	8.944857e-6
GO:0061113	pancreas morphogenesis	9.869959e-6
GO:0006825	copper ion transport	1.001754e-5
GO:0010466	negative regulation of peptidase activity	1.010160e-5
GO:0042743	hydrogen peroxide metabolic process	1.029692e-5
GO:0042996	regulation of Golgi to plasma membrane protein transport	1.060300e-5
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	1.086741e-5
GO:0090362	positive regulation of platelet-derived growth factor production	1.090030e-5
GO:0090336	positive regulation of brown fat cell differentiation	1.090030e-5
GO:0090271	positive regulation of fibroblast growth factor production	1.090030e-5
GO:0010035	response to inorganic substance	1.140511e-5
GO:0008608	attachment of spindle microtubules to kinetochore	1.170963e-5
GO:0090083	regulation of inclusion body assembly	1.366986e-5
GO:0035814	negative regulation of renal sodium excretion	1.366986e-5
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.564986e-5
GO:0045401	positive regulation of interleukin-3 biosynthetic process	1.564986e-5
GO:0006054	N-acetylneuraminate metabolic process	1.582674e-5
GO:0006188	IMP biosynthetic process	1.719136e-5
GO:0006979	response to oxidative stress	1.985416e-5
GO:0044281	small molecule metabolic process	2.195934e-5
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	2.309961e-5
GO:0032074	negative regulation of nuclease activity	2.410282e-5
GO:0048285	organelle fission	2.479720e-5
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	2.500158e-5
GO:0042364	water-soluble vitamin biosynthetic process	2.701863e-5
GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling	3.237211e-5
GO:0045444	fat cell differentiation	3.338006e-5
GO:0006302	double-strand break repair	3.535965e-5
GO:0043122	regulation of I-kappaB kinase/NF-kappaB cascade	3.682239e-5
GO:0010038	response to metal ion	3.827972e-5
GO:0046689	response to mercury ion	3.856752e-5
GO:0006144	purine base metabolic process	4.135827e-5
GO:0019430	removal of superoxide radicals	4.197914e-5
GO:0032060	bleb assembly	4.462098e-5
GO:0030819	positive regulation of cAMP biosynthetic process	4.784571e-5
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	4.963339e-5
GO:0034114	regulation of heterotypic cell-cell adhesion	4.963339e-5
GO:0022403	cell cycle phase	5.298330e-5
GO:0043624	cellular protein complex disassembly	5.492013e-5
GO:0046483	heterocycle metabolic process	6.099545e-5
GO:0032025	response to cobalt ion	6.560444e-5
GO:0043366	beta selection	6.894953e-5
GO:0048710	regulation of astrocyte differentiation	7.299228e-5
GO:0050850	positive regulation of calcium-mediated signaling	7.330510e-5
GO:0009156	ribonucleoside monophosphate biosynthetic process	7.331043e-5
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	7.372831e-5
GO:0044092	negative regulation of molecular function	7.378989e-5
GO:0007067	mitosis	7.611208e-5
GO:0046415	urate metabolic process	7.875664e-5
GO:0033578	protein glycosylation in Golgi	8.801164e-5
GO:0000103	sulfate assimilation	8.853689e-5
GO:0006412	translation	9.009538e-5
GO:0009181	purine ribonucleoside diphosphate catabolic process	9.286289e-5
GO:0009120	deoxyribonucleoside metabolic process	9.286289e-5
GO:0042998	positive regulation of Golgi to plasma membrane protein transport	1.034365e-4
GO:0042703	menstruation	1.034365e-4
GO:0019101	female somatic sex determination	1.034365e-4
GO:0045428	regulation of nitric oxide biosynthetic process	1.051981e-4
GO:0032241	positive regulation of nucleobase-containing compound transport	1.130438e-4
GO:0006391	transcription initiation from mitochondrial promoter	1.130438e-4
GO:0019371	cyclooxygenase pathway	1.172712e-4
GO:0032495	response to muramyl dipeptide	1.176714e-4
GO:0000303	response to superoxide	1.195570e-4
GO:0006633	fatty acid biosynthetic process	1.245741e-4
GO:0002313	mature B cell differentiation involved in immune response	1.268828e-4
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	1.271619e-4
GO:0046031	ADP metabolic process	1.372210e-4
GO:0034115	negative regulation of heterotypic cell-cell adhesion	1.411451e-4
GO:0006982	response to lipid hydroperoxide	1.441993e-4
GO:0010310	regulation of hydrogen peroxide metabolic process	1.461156e-4
GO:0032494	response to peptidoglycan	1.470317e-4
GO:0009185	ribonucleoside diphosphate metabolic process	1.550962e-4
GO:0043241	protein complex disassembly	1.550962e-4
GO:0006882	cellular zinc ion homeostasis	1.569293e-4
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.665713e-4
GO:0032463	negative regulation of protein homooligomerization	1.670036e-4
GO:0060018	astrocyte fate commitment	1.749199e-4
GO:0000087	M phase of mitotic cell cycle	1.873604e-4
GO:0030804	positive regulation of cyclic nucleotide biosynthetic process	1.876251e-4
GO:0015684	ferrous iron transport	1.948869e-4
GO:0050849	negative regulation of calcium-mediated signaling	1.991933e-4
GO:2000347	positive regulation of hepatocyte proliferation	2.024925e-4
GO:0006672	ceramide metabolic process	2.044415e-4
GO:0006214	thymidine catabolic process	2.146906e-4
GO:0051346	negative regulation of hydrolase activity	2.190747e-4
GO:0034623	cellular macromolecular complex disassembly	2.328582e-4
GO:0071901	negative regulation of protein serine/threonine kinase activity	2.460593e-4
GO:0006408	snRNA export from nucleus	2.630816e-4
GO:0030521	androgen receptor signaling pathway	2.723538e-4
GO:0001920	negative regulation of receptor recycling	2.727953e-4
GO:0007254	JNK cascade	2.731833e-4
GO:2000522	positive regulation of immunological synapse formation	2.761082e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	2.761082e-4
GO:0048213	Golgi vesicle prefusion complex stabilization	2.794795e-4
GO:0002312	B cell activation involved in immune response	2.856082e-4
GO:0031573	intra-S DNA damage checkpoint	2.932602e-4
GO:0038003	opioid receptor signaling pathway	2.973557e-4
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	3.065261e-4
GO:0045116	protein neddylation	3.078364e-4
GO:0051348	negative regulation of transferase activity	3.087057e-4
GO:0072573	tolerance induction to lipopolysaccharide	3.140132e-4
GO:2000349	negative regulation of CD40 signaling pathway	3.140132e-4
GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	3.140132e-4
GO:0034148	negative regulation of toll-like receptor 5 signaling pathway	3.140132e-4
GO:0070429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	3.140132e-4
GO:0002632	negative regulation of granuloma formation	3.140132e-4
GO:0007256	activation of JNKK activity	3.141997e-4
GO:0006534	cysteine metabolic process	3.141997e-4
GO:0055090	acylglycerol homeostasis	3.272123e-4
GO:0002335	mature B cell differentiation	3.406899e-4
GO:0033673	negative regulation of kinase activity	3.448829e-4
GO:0009566	fertilization	3.504193e-4
GO:0044273	sulfur compound catabolic process	3.530591e-4
GO:0055069	zinc ion homeostasis	3.546978e-4
GO:0002676	regulation of chronic inflammatory response	3.549003e-4
GO:0000041	transition metal ion transport	3.922560e-4
GO:0006207	'de novo' pyrimidine base biosynthetic process	4.114174e-4
GO:0061072	iris morphogenesis	4.121655e-4
GO:0050873	brown fat cell differentiation	4.198269e-4
GO:0006833	water transport	4.208429e-4
GO:0030801	positive regulation of cyclic nucleotide metabolic process	4.339761e-4
GO:0045128	negative regulation of reciprocal meiotic recombination	4.508242e-4
GO:0006561	proline biosynthetic process	4.508242e-4
GO:0006311	meiotic gene conversion	4.508242e-4
GO:0000305	response to oxygen radical	4.566486e-4
GO:0032984	macromolecular complex disassembly	4.643050e-4
GO:0010520	regulation of reciprocal meiotic recombination	4.802392e-4
GO:0009113	purine base biosynthetic process	4.875974e-4
GO:0032720	negative regulation of tumor necrosis factor production	4.905514e-4
GO:0006414	translational elongation	5.049733e-4
GO:0006469	negative regulation of protein kinase activity	5.131500e-4
GO:0071361	cellular response to ethanol	5.137301e-4
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade	5.399344e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	6.149814e-4
GO:0009956	radial pattern formation	6.204960e-4
GO:0006212	uracil catabolic process	6.375375e-4
GO:0030148	sphingolipid biosynthetic process	6.395567e-4
GO:0051586	positive regulation of dopamine uptake	6.805282e-4
GO:0035037	sperm entry	7.129495e-4
GO:0015842	synaptic vesicle amine transport	7.129495e-4
GO:0006767	water-soluble vitamin metabolic process	7.145667e-4
GO:0061077	chaperone-mediated protein folding	7.158843e-4
GO:0005978	glycogen biosynthetic process	7.320263e-4
GO:0042742	defense response to bacterium	7.426774e-4
GO:0046519	sphingoid metabolic process	7.491036e-4
GO:0000710	meiotic mismatch repair	7.582556e-4
GO:0048712	negative regulation of astrocyte differentiation	7.629144e-4
GO:0033865	nucleoside bisphosphate metabolic process	7.737795e-4
GO:0052547	regulation of peptidase activity	8.595573e-4
GO:0051707	response to other organism	8.723181e-4
GO:0045226	extracellular polysaccharide biosynthetic process	8.993990e-4
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	8.993990e-4
GO:0015809	arginine transport	9.621501e-4
GO:0007258	JUN phosphorylation	9.621501e-4
GO:0051584	regulation of dopamine uptake	9.634006e-4
GO:0015840	urea transport	9.634006e-4
GO:0070541	response to platinum ion	9.637572e-4
GO:0046500	S-adenosylmethionine metabolic process	9.637572e-4
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	9.655659e-4
GO:0019438	aromatic compound biosynthetic process	9.661922e-4
GO:0009110	vitamin biosynthetic process	9.661922e-4
GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	9.788173e-4
GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	9.788173e-4
GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	9.788173e-4
GO:0009112	nucleobase metabolic process	1.000734e-3
GO:0070574	cadmium ion transmembrane transport	1.009077e-3
GO:0051383	kinetochore organization	1.020073e-3
GO:0032225	regulation of synaptic transmission, dopaminergic	1.046422e-3
GO:0010665	regulation of cardiac muscle cell apoptosis	1.068451e-3
GO:0051225	spindle assembly	1.081372e-3
GO:0000724	double-strand break repair via homologous recombination	1.089184e-3
GO:0033692	cellular polysaccharide biosynthetic process	1.147777e-3
GO:0072521	purine-containing compound metabolic process	1.170219e-3
GO:0002315	marginal zone B cell differentiation	1.171696e-3
GO:0046467	membrane lipid biosynthetic process	1.174630e-3
GO:0051261	protein depolymerization	1.181106e-3
GO:0042640	anagen	1.201772e-3
GO:0006418	tRNA aminoacylation for protein translation	1.202014e-3
GO:0071312	cellular response to alkaloid	1.204570e-3
GO:0015074	DNA integration	1.204570e-3
GO:0070934	CRD-mediated mRNA stabilization	1.213487e-3
GO:0046833	positive regulation of RNA export from nucleus	1.252875e-3
GO:0070535	histone H2A K63-linked ubiquitination	1.252875e-3
GO:0002418	immune response to tumor cell	1.252875e-3
GO:0045987	positive regulation of smooth muscle contraction	1.259898e-3
GO:0044062	regulation of excretion	1.261729e-3
GO:0051295	establishment of meiotic spindle localization	1.342943e-3
GO:0042044	fluid transport	1.421993e-3
GO:0042554	superoxide anion generation	1.434729e-3
GO:0018202	peptidyl-histidine modification	1.435962e-3
GO:0055086	nucleobase-containing small molecule metabolic process	1.437696e-3
GO:0048936	peripheral nervous system neuron axonogenesis	1.439142e-3
GO:0060302	negative regulation of cytokine activity	1.439142e-3
GO:2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	1.439142e-3
GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	1.439142e-3
GO:0045751	negative regulation of Toll signaling pathway	1.439142e-3
GO:0032790	ribosome disassembly	1.439142e-3
GO:0031119	tRNA pseudouridine synthesis	1.439142e-3
GO:0006780	uroporphyrinogen III biosynthetic process	1.439142e-3
GO:0032543	mitochondrial translation	1.439142e-3
GO:0006419	alanyl-tRNA aminoacylation	1.484677e-3
GO:0010042	response to manganese ion	1.489195e-3
GO:0019835	cytolysis	1.494328e-3
GO:0007019	microtubule depolymerization	1.498519e-3
GO:0031998	regulation of fatty acid beta-oxidation	1.536398e-3
GO:0048820	hair follicle maturation	1.538511e-3
GO:0009617	response to bacterium	1.637642e-3
GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.653668e-3
GO:0031100	organ regeneration	1.665301e-3
GO:0044249	cellular biosynthetic process	1.693795e-3
GO:0090307	spindle assembly involved in mitosis	1.748371e-3
GO:0010457	centriole-centriole cohesion	1.748371e-3
GO:0006026	aminoglycan catabolic process	1.811945e-3
GO:0060631	regulation of meiosis I	1.843206e-3
GO:0030641	regulation of cellular pH	1.848400e-3
GO:0007132	meiotic metaphase I	1.848941e-3
GO:0055085	transmembrane transport	1.886775e-3
GO:0007126	meiosis	1.893128e-3
GO:0000278	mitotic cell cycle	1.908666e-3
GO:0009311	oligosaccharide metabolic process	1.929129e-3
GO:0000725	recombinational repair	1.985782e-3
GO:0043066	negative regulation of apoptosis	2.093125e-3
GO:0090361	regulation of platelet-derived growth factor production	2.102679e-3
GO:0051533	positive regulation of NFAT protein import into nucleus	2.102679e-3
GO:0060564	negative regulation of mitotic anaphase-promoting complex activity	2.104989e-3
GO:0042416	dopamine biosynthetic process	2.122140e-3
GO:2000348	regulation of CD40 signaling pathway	2.152912e-3
GO:0071279	cellular response to cobalt ion	2.161724e-3
GO:0046724	oxalic acid secretion	2.161724e-3
GO:0010637	negative regulation of mitochondrial fusion	2.161724e-3
GO:0019265	glycine biosynthetic process, by transamination of glyoxylate	2.161724e-3
GO:0007159	leukocyte cell-cell adhesion	2.181271e-3
GO:0051704	multi-organism process	2.238289e-3
GO:0000079	regulation of cyclin-dependent protein kinase activity	2.256535e-3
GO:0051297	centrosome organization	2.267615e-3
GO:0043968	histone H2A acetylation	2.276379e-3
GO:0050892	intestinal absorption	2.280312e-3
GO:0043069	negative regulation of programmed cell death	2.307461e-3
GO:0010739	positive regulation of protein kinase A signaling cascade	2.311522e-3
GO:0046512	sphingosine biosynthetic process	2.311522e-3
GO:0043306	positive regulation of mast cell degranulation	2.319327e-3
GO:0006667	sphinganine metabolic process	2.332983e-3
GO:0060730	regulation of intestinal epithelial structure maintenance	2.367977e-3
GO:0035883	enteroendocrine cell differentiation	2.367977e-3
GO:0010312	detoxification of zinc ion	2.367977e-3
GO:0002252	immune effector process	2.409180e-3
GO:0030004	cellular monovalent inorganic cation homeostasis	2.434381e-3
GO:0009259	ribonucleotide metabolic process	2.463871e-3
GO:0051301	cell division	2.482973e-3
GO:0090270	regulation of fibroblast growth factor production	2.498240e-3
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	2.506680e-3
GO:0071705	nitrogen compound transport	2.589152e-3
GO:0051438	regulation of ubiquitin-protein ligase activity	2.605643e-3
GO:0032680	regulation of tumor necrosis factor production	2.671282e-3
GO:0021781	glial cell fate commitment	2.679145e-3
GO:0045604	regulation of epidermal cell differentiation	2.679145e-3
GO:0034139	regulation of toll-like receptor 3 signaling pathway	2.699047e-3
GO:0051788	response to misfolded protein	2.700687e-3
GO:0016052	carbohydrate catabolic process	2.708270e-3
GO:0031098	stress-activated protein kinase signaling cascade	2.713372e-3
GO:0009268	response to pH	2.734764e-3
GO:0046485	ether lipid metabolic process	2.749243e-3
GO:0070536	protein K63-linked deubiquitination	2.825720e-3
GO:0009161	ribonucleoside monophosphate metabolic process	2.844035e-3
GO:0051006	positive regulation of lipoprotein lipase activity	2.850695e-3
GO:0015820	leucine transport	2.882589e-3
GO:0044314	protein K27-linked ubiquitination	2.892934e-3
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	2.898429e-3
GO:0061325	cell proliferation involved in outflow tract morphogenesis	2.898429e-3
GO:0009313	oligosaccharide catabolic process	2.915187e-3
GO:0007596	blood coagulation	2.917425e-3
GO:0010898	positive regulation of triglyceride catabolic process	3.016855e-3
GO:0034445	negative regulation of plasma lipoprotein particle oxidation	3.083667e-3
GO:0051883	killing of cells in other organism involved in symbiotic interaction	3.100196e-3
GO:0009896	positive regulation of catabolic process	3.119686e-3
GO:0048708	astrocyte differentiation	3.137514e-3
GO:0050746	regulation of lipoprotein metabolic process	3.140841e-3
GO:0032897	negative regulation of viral transcription	3.169530e-3
GO:0015672	monovalent inorganic cation transport	3.239539e-3
GO:0051340	regulation of ligase activity	3.264855e-3
GO:0000272	polysaccharide catabolic process	3.275498e-3
GO:0009058	biosynthetic process	3.293327e-3
GO:0071918	urea transmembrane transport	3.318033e-3
GO:0060586	multicellular organismal iron ion homeostasis	3.318033e-3
GO:0019344	cysteine biosynthetic process	3.318033e-3
GO:0002074	extraocular skeletal muscle development	3.318033e-3
GO:0034021	response to silicon dioxide	3.371766e-3
GO:0048773	erythrophore differentiation	3.371766e-3
GO:0007624	ultradian rhythm	3.371766e-3
GO:0001315	age-dependent response to reactive oxygen species	3.371766e-3
GO:0002357	defense response to tumor cell	3.371766e-3
GO:0003069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	3.371766e-3
GO:0009124	nucleoside monophosphate biosynthetic process	3.405279e-3
GO:0031638	zymogen activation	3.425109e-3
GO:0051154	negative regulation of striated muscle cell differentiation	3.457255e-3
GO:0031915	positive regulation of synaptic plasticity	3.471920e-3
GO:0031640	killing of cells of other organism	3.476298e-3
GO:0021571	rhombomere 5 development	3.546819e-3
GO:0060379	cardiac muscle cell myoblast differentiation	3.547726e-3
GO:0018993	somatic sex determination	3.547726e-3
GO:0018095	protein polyglutamylation	3.547726e-3
GO:0046479	glycosphingolipid catabolic process	3.553685e-3
GO:0002369	T cell cytokine production	3.553685e-3
GO:0045732	positive regulation of protein catabolic process	3.562142e-3
GO:0070256	negative regulation of mucus secretion	3.579285e-3
GO:0035786	protein complex oligomerization	3.579285e-3
GO:0048627	myoblast development	3.579285e-3
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	3.579285e-3
GO:0046502	uroporphyrinogen III metabolic process	3.579285e-3
GO:0006826	iron ion transport	3.595410e-3
GO:0051096	positive regulation of helicase activity	3.640091e-3
GO:0050665	hydrogen peroxide biosynthetic process	3.661279e-3
GO:0009117	nucleotide metabolic process	3.674511e-3
GO:0007599	hemostasis	3.728930e-3
GO:0008610	lipid biosynthetic process	3.733831e-3
GO:0006446	regulation of translational initiation	3.741821e-3
GO:0060548	negative regulation of cell death	3.788345e-3
GO:0010575	positive regulation vascular endothelial growth factor production	3.801836e-3
GO:0031056	regulation of histone modification	3.827237e-3
GO:0001922	B-1 B cell homeostasis	3.863661e-3
GO:0034614	cellular response to reactive oxygen species	3.871146e-3
GO:0010656	negative regulation of muscle cell apoptosis	3.891134e-3
GO:0033005	positive regulation of mast cell activation	3.950314e-3
GO:0046638	positive regulation of alpha-beta T cell differentiation	4.001240e-3
GO:0006413	translational initiation	4.039603e-3
GO:0051321	meiotic cell cycle	4.115134e-3
GO:0042886	amide transport	4.127970e-3
GO:0044271	cellular nitrogen compound biosynthetic process	4.165492e-3
GO:0042074	cell migration involved in gastrulation	4.168184e-3
GO:0034372	very-low-density lipoprotein particle remodeling	4.168184e-3
GO:0045600	positive regulation of fat cell differentiation	4.306330e-3
GO:0046533	negative regulation of photoreceptor cell differentiation	4.316421e-3
GO:0002367	cytokine production involved in immune response	4.325191e-3
GO:0035329	hippo signaling cascade	4.347489e-3
GO:0045429	positive regulation of nitric oxide biosynthetic process	4.349387e-3
GO:0051220	cytoplasmic sequestering of protein	4.353768e-3
GO:0046532	regulation of photoreceptor cell differentiation	4.353768e-3
GO:0044241	lipid digestion	4.468785e-3
GO:0050862	positive regulation of T cell receptor signaling pathway	4.473819e-3
GO:0015802	basic amino acid transport	4.500757e-3
GO:0033076	isoquinoline alkaloid metabolic process	4.519102e-3
GO:0052314	phytoalexin metabolic process	4.519102e-3
GO:0006783	heme biosynthetic process	4.543401e-3
GO:0003032	detection of oxygen	4.549879e-3
GO:0060555	induction of necroptosis by extracellular signals	4.549879e-3
GO:0002230	positive regulation of defense response to virus by host	4.549879e-3
GO:0006069	ethanol oxidation	4.614312e-3
GO:0006210	thymine catabolic process	4.614312e-3
GO:0001881	receptor recycling	4.614312e-3
GO:0002710	negative regulation of T cell mediated immunity	4.729579e-3
GO:0043302	positive regulation of leukocyte degranulation	4.793279e-3
GO:0006824	cobalt ion transport	4.793279e-3
GO:0009179	purine ribonucleoside diphosphate metabolic process	4.793279e-3
GO:0072593	reactive oxygen species metabolic process	4.892806e-3
GO:0045588	positive regulation of gamma-delta T cell differentiation	4.896838e-3
GO:0051099	positive regulation of binding	4.897377e-3
GO:0060677	ureteric bud elongation	4.944000e-3
GO:0045682	regulation of epidermis development	5.014304e-3
GO:0032715	negative regulation of interleukin-6 production	5.021965e-3
GO:0034442	regulation of lipoprotein oxidation	5.084670e-3
GO:0044240	multicellular organismal lipid catabolic process	5.113551e-3
GO:0010765	positive regulation of sodium ion transport	5.113551e-3
GO:0046124	purine deoxyribonucleoside catabolic process	5.171470e-3
GO:0051382	kinetochore assembly	5.209316e-3
GO:0035881	amacrine cell differentiation	5.209316e-3
GO:0045162	clustering of voltage-gated sodium channels	5.257500e-3
GO:0019448	L-cysteine catabolic process	5.257500e-3
GO:0000096	sulfur amino acid metabolic process	5.336037e-3
GO:0045684	positive regulation of epidermis development	5.388099e-3
GO:0051444	negative regulation of ubiquitin-protein ligase activity	5.389871e-3
GO:0010002	cardioblast differentiation	5.464580e-3
GO:2000345	regulation of hepatocyte proliferation	5.465816e-3
GO:0032069	regulation of nuclease activity	5.485474e-3
GO:0048034	heme O biosynthetic process	5.533972e-3
GO:0006649	phospholipid transfer to membrane	5.533972e-3
GO:0046148	pigment biosynthetic process	5.547766e-3
GO:0090005	negative regulation of establishment of protein localization in plasma membrane	5.588990e-3
GO:0071421	manganese ion transmembrane transport	5.632548e-3
GO:0034612	response to tumor necrosis factor	5.677948e-3
GO:0021612	facial nerve structural organization	5.691334e-3
GO:0050996	positive regulation of lipid catabolic process	5.718748e-3
GO:0061136	regulation of proteasomal protein catabolic process	5.796962e-3
GO:0035434	copper ion transmembrane transport	5.885912e-3
GO:0006167	AMP biosynthetic process	5.949480e-3
GO:0030224	monocyte differentiation	5.980782e-3
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	6.001025e-3
GO:0034370	triglyceride-rich lipoprotein particle remodeling	6.010864e-3
GO:0045665	negative regulation of neuron differentiation	6.014715e-3
GO:0043900	regulation of multi-organism process	6.051347e-3
GO:0002440	production of molecular mediator of immune response	6.151063e-3
GO:0010660	regulation of muscle cell apoptosis	6.260889e-3
GO:0061010	gall bladder development	6.271941e-3
GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	6.283451e-3
GO:0006689	ganglioside catabolic process	6.283451e-3
GO:0016480	negative regulation of transcription from RNA polymerase III promoter	6.283451e-3
GO:0043922	negative regulation by host of viral transcription	6.339532e-3
GO:0031532	actin cytoskeleton reorganization	6.377971e-3
GO:0048311	mitochondrion distribution	6.452761e-3
GO:0032606	type I interferon production	6.452761e-3
GO:0009607	response to biotic stimulus	6.580532e-3
GO:0018130	heterocycle biosynthetic process	6.750588e-3
GO:0006091	generation of precursor metabolites and energy	6.762976e-3
GO:0031023	microtubule organizing center organization	6.855469e-3
GO:0032411	positive regulation of transporter activity	6.857404e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.872081e-3
GO:0006163	purine nucleotide metabolic process	6.874022e-3
GO:0045823	positive regulation of heart contraction	7.031172e-3
GO:0033622	integrin activation	7.061685e-3
GO:0051238	sequestering of metal ion	7.090093e-3
GO:0035372	protein localization to microtubule	7.090093e-3
GO:0006705	mineralocorticoid biosynthetic process	7.090093e-3
GO:0006027	glycosaminoglycan catabolic process	7.090093e-3
GO:0002832	negative regulation of response to biotic stimulus	7.137102e-3
GO:0051592	response to calcium ion	7.184151e-3
GO:0006635	fatty acid beta-oxidation	7.185996e-3
GO:2000736	regulation of stem cell differentiation	7.187444e-3
GO:0002861	regulation of inflammatory response to antigenic stimulus	7.302622e-3
GO:0060836	lymphatic endothelial cell differentiation	7.323326e-3
GO:0016557	peroxisome membrane biogenesis	7.338298e-3
GO:0009167	purine ribonucleoside monophosphate metabolic process	7.393787e-3
GO:0000097	sulfur amino acid biosynthetic process	7.478755e-3
GO:0070265	necrotic cell death	7.478933e-3
GO:0072086	specification of loop of Henle identity	7.478933e-3
GO:0006379	mRNA cleavage	7.552873e-3
GO:0010977	negative regulation of neuron projection development	7.567815e-3
GO:0044058	regulation of digestive system process	7.608240e-3
GO:0051580	regulation of neurotransmitter uptake	7.640477e-3
GO:0061015	snRNA import into nucleus	7.808458e-3
GO:0046683	response to organophosphorus	7.808458e-3
GO:0046653	tetrahydrofolate metabolic process	7.888974e-3
GO:0006828	manganese ion transport	8.036474e-3
GO:0042176	regulation of protein catabolic process	8.155043e-3
GO:0071288	cellular response to mercury ion	8.224273e-3
GO:0033194	response to hydroperoxide	8.277323e-3
GO:0032462	regulation of protein homooligomerization	8.277323e-3
GO:0035813	regulation of renal sodium excretion	8.295717e-3
GO:0048711	positive regulation of astrocyte differentiation	8.348976e-3
GO:0015793	glycerol transport	8.372681e-3
GO:0051095	regulation of helicase activity	8.404268e-3
GO:0008206	bile acid metabolic process	8.474186e-3
GO:0070781	response to biotin	8.478096e-3
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	8.478096e-3
GO:0032692	negative regulation of interleukin-1 production	8.498854e-3
GO:0030050	vesicle transport along actin filament	8.743041e-3
GO:0016973	poly(A)+ mRNA export from nucleus	8.743041e-3
GO:0048670	regulation of collateral sprouting	8.798184e-3
GO:0045636	positive regulation of melanocyte differentiation	8.798184e-3
GO:2000275	regulation of oxidative phosphorylation uncoupler activity	8.840309e-3
GO:0002426	immunoglobulin production in mucosal tissue	8.863166e-3
GO:0050882	voluntary musculoskeletal movement	8.919584e-3
GO:0033574	response to testosterone stimulus	9.083645e-3
GO:0051186	cofactor metabolic process	9.118157e-3
GO:0009084	glutamine family amino acid biosynthetic process	9.132756e-3
GO:0042753	positive regulation of circadian rhythm	9.170138e-3
GO:0031953	negative regulation of protein autophosphorylation	9.186349e-3
GO:0071702	organic substance transport	9.199102e-3
GO:0015849	organic acid transport	9.474516e-3
GO:0006732	coenzyme metabolic process	9.506251e-3
GO:0051313	attachment of spindle microtubules to chromosome	9.603212e-3