Novel motif:149

name:	motif149_CAAGCTGTACA

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0030168	platelet activation	2.190373e-18
GO:0050878	regulation of body fluid levels	4.954777e-16
GO:0009611	response to wounding	8.034595e-16
GO:0007596	blood coagulation	9.266860e-16
GO:0007599	hemostasis	1.415482e-15
GO:0042060	wound healing	2.904514e-15
GO:0006950	response to stress	9.860731e-13
GO:0050896	response to stimulus	2.031221e-11
GO:0001775	cell activation	1.584653e-10
GO:0009888	tissue development	2.436377e-10
GO:0071379	cellular response to prostaglandin stimulus	2.590745e-10
GO:0006928	cellular component movement	7.062107e-10
GO:0051085	chaperone mediated protein folding requiring cofactor	7.256977e-10
GO:0021509	roof plate formation	1.139496e-9
GO:0010886	positive regulation of cholesterol storage	7.173104e-9
GO:0060571	morphogenesis of an epithelial fold	7.807283e-9
GO:0019087	transformation of host cell by virus	8.593972e-9
GO:0044281	small molecule metabolic process	1.412470e-8
GO:0001701	in utero embryonic development	3.048538e-8
GO:0051967	negative regulation of synaptic transmission, glutamatergic	4.108488e-8
GO:0021527	spinal cord association neuron differentiation	5.670657e-8
GO:0034694	response to prostaglandin stimulus	5.744481e-8
GO:0006642	triglyceride mobilization	5.833419e-8
GO:0031329	regulation of cellular catabolic process	6.776398e-8
GO:0018149	peptide cross-linking	7.200274e-8
GO:0060840	artery development	7.939743e-8
GO:0070884	regulation of calcineurin-NFAT signaling pathway	1.224994e-7
GO:0061101	neuroendocrine cell differentiation	1.631310e-7
GO:0010269	response to selenium ion	1.714917e-7
GO:0019441	tryptophan catabolic process to kynurenine	2.396987e-7
GO:0010744	positive regulation of macrophage derived foam cell differentiation	2.635867e-7
GO:0050769	positive regulation of neurogenesis	2.920884e-7
GO:0003094	glomerular filtration	3.843707e-7
GO:0040040	thermosensory behavior	4.384276e-7
GO:0032501	multicellular organismal process	4.641836e-7
GO:0050900	leukocyte migration	4.764407e-7
GO:0071404	cellular response to low-density lipoprotein particle stimulus	6.287363e-7
GO:0007585	respiratory gaseous exchange	6.968600e-7
GO:0051290	protein heterotetramerization	7.706795e-7
GO:0002830	positive regulation of type 2 immune response	8.172109e-7
GO:0070189	kynurenine metabolic process	8.728264e-7
GO:0007165	signal transduction	1.036620e-6
GO:0090023	positive regulation of neutrophil chemotaxis	1.096348e-6
GO:0072136	metanephric mesenchymal cell proliferation involved in metanephros development	1.155574e-6
GO:0048844	artery morphogenesis	1.229846e-6
GO:0048514	blood vessel morphogenesis	1.275557e-6
GO:0009268	response to pH	1.279819e-6
GO:0023052	signaling	1.306520e-6
GO:0034014	response to triglyceride	1.341912e-6
GO:0060080	regulation of inhibitory postsynaptic membrane potential	1.351076e-6
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	1.514336e-6
GO:0051865	protein autoubiquitination	1.520505e-6
GO:0007154	cell communication	1.677738e-6
GO:0050772	positive regulation of axonogenesis	1.701514e-6
GO:0048646	anatomical structure formation involved in morphogenesis	1.725317e-6
GO:0021530	spinal cord oligodendrocyte cell fate specification	1.857699e-6
GO:0042180	cellular ketone metabolic process	1.936449e-6
GO:0000244	assembly of spliceosomal tri-snRNP	2.102003e-6
GO:0065008	regulation of biological quality	2.256240e-6
GO:0060164	regulation of timing of neuron differentiation	2.367418e-6
GO:0042159	lipoprotein catabolic process	2.466713e-6
GO:0042953	lipoprotein transport	2.477179e-6
GO:0010884	positive regulation of lipid storage	2.559382e-6
GO:0035524	proline transmembrane transport	2.693575e-6
GO:0071402	cellular response to lipoprotein particle stimulus	2.701254e-6
GO:0007166	cell surface receptor linked signaling pathway	2.827801e-6
GO:0006140	regulation of nucleotide metabolic process	2.952329e-6
GO:0030048	actin filament-based movement	3.258698e-6
GO:0001525	angiogenesis	3.346553e-6
GO:0071460	cellular response to cell-matrix adhesion	3.373531e-6
GO:0051716	cellular response to stimulus	3.523656e-6
GO:0006082	organic acid metabolic process	3.628709e-6
GO:0002576	platelet degranulation	3.767614e-6
GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	4.019599e-6
GO:0032660	regulation of interleukin-17 production	4.342438e-6
GO:0019752	carboxylic acid metabolic process	4.443778e-6
GO:0032355	response to estradiol stimulus	4.482724e-6
GO:0015804	neutral amino acid transport	4.568542e-6
GO:0006200	ATP catabolic process	4.678298e-6
GO:0048771	tissue remodeling	4.697650e-6
GO:0035710	CD4-positive, alpha-beta T cell activation	4.741635e-6
GO:0061102	stomach neuroendocrine cell differentiation	4.810047e-6
GO:0061103	carotid body glomus cell differentiation	4.810047e-6
GO:0061104	adrenal chromaffin cell differentiation	4.810047e-6
GO:0071259	cellular response to magnetism	4.810047e-6
GO:0060165	regulation of timing of subpallium neuron differentiation	4.810047e-6
GO:0061100	lung neuroendocrine cell differentiation	4.810047e-6
GO:0007400	neuroblast fate determination	4.810047e-6
GO:0003359	noradrenergic neuron fate commitment	4.810047e-6
GO:0060163	subpallium neuron fate commitment	4.810047e-6
GO:0045190	isotype switching	4.900494e-6
GO:0016477	cell migration	4.989374e-6
GO:0060174	limb bud formation	5.158835e-6
GO:0050709	negative regulation of protein secretion	5.387218e-6
GO:0045540	regulation of cholesterol biosynthetic process	5.817429e-6
GO:0046631	alpha-beta T cell activation	5.839093e-6
GO:0006629	lipid metabolic process	6.012930e-6
GO:0007205	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	6.304954e-6
GO:0050790	regulation of catalytic activity	6.479711e-6
GO:0043462	regulation of ATPase activity	6.786282e-6
GO:0033121	regulation of purine nucleotide catabolic process	7.029177e-6
GO:0021515	cell differentiation in spinal cord	7.501354e-6
GO:0071347	cellular response to interleukin-1	7.556794e-6
GO:0015986	ATP synthesis coupled proton transport	8.041744e-6
GO:0010885	regulation of cholesterol storage	9.053228e-6
GO:0016310	phosphorylation	9.157800e-6
GO:0043627	response to estrogen stimulus	9.208199e-6
GO:0060166	olfactory pit development	1.044840e-5
GO:0034383	low-density lipoprotein particle clearance	1.068725e-5
GO:0050863	regulation of T cell activation	1.075142e-5
GO:0046456	icosanoid biosynthetic process	1.096639e-5
GO:0032700	negative regulation of interleukin-17 production	1.115321e-5
GO:0046687	response to chromate	1.117346e-5
GO:0033986	response to methanol	1.117346e-5
GO:0030198	extracellular matrix organization	1.140706e-5
GO:0043085	positive regulation of catalytic activity	1.221035e-5
GO:0006386	termination of RNA polymerase III transcription	1.233501e-5
GO:0006385	transcription elongation from RNA polymerase III promoter	1.233501e-5
GO:0034379	very-low-density lipoprotein particle assembly	1.287039e-5
GO:0014850	response to muscle activity	1.299744e-5
GO:0030509	BMP signaling pathway	1.422061e-5
GO:0021516	dorsal spinal cord development	1.432505e-5
GO:0045056	transcytosis	1.433790e-5
GO:0040011	locomotion	1.487533e-5
GO:0061036	positive regulation of cartilage development	1.522105e-5
GO:0045059	positive thymic T cell selection	1.610610e-5
GO:0035556	intracellular signal transduction	1.787583e-5
GO:0048870	cell motility	1.866059e-5
GO:0048545	response to steroid hormone stimulus	1.885296e-5
GO:0006575	cellular modified amino acid metabolic process	1.910038e-5
GO:0050849	negative regulation of calcium-mediated signaling	1.932909e-5
GO:0006520	cellular amino acid metabolic process	1.954051e-5
GO:0048685	negative regulation of collateral sprouting of intact axon in response to injury	2.013167e-5
GO:0042730	fibrinolysis	2.262500e-5
GO:0070252	actin-mediated cell contraction	2.276910e-5
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	2.319360e-5
GO:0035691	macrophage migration inhibitory factor signaling pathway	2.319360e-5
GO:0001974	blood vessel remodeling	2.363027e-5
GO:0046632	alpha-beta T cell differentiation	2.426180e-5
GO:0042129	regulation of T cell proliferation	2.567323e-5
GO:0002312	B cell activation involved in immune response	2.606629e-5
GO:0090141	positive regulation of mitochondrial fission	2.643003e-5
GO:0051336	regulation of hydrolase activity	2.669832e-5
GO:0060662	salivary gland cavitation	2.687083e-5
GO:0009894	regulation of catabolic process	2.725221e-5
GO:0050708	regulation of protein secretion	2.766620e-5
GO:0060033	anatomical structure regression	2.793573e-5
GO:0015696	ammonium transport	2.843507e-5
GO:0032526	response to retinoic acid	2.864272e-5
GO:0046007	negative regulation of activated T cell proliferation	2.869630e-5
GO:0032972	regulation of muscle filament sliding speed	2.969162e-5
GO:0031032	actomyosin structure organization	2.979408e-5
GO:0006636	unsaturated fatty acid biosynthetic process	3.012368e-5
GO:0006898	receptor-mediated endocytosis	3.140492e-5
GO:0051048	negative regulation of secretion	3.250656e-5
GO:0042130	negative regulation of T cell proliferation	3.427436e-5
GO:0045907	positive regulation of vasoconstriction	3.441200e-5
GO:0046034	ATP metabolic process	3.481375e-5
GO:0033092	positive regulation of immature T cell proliferation in thymus	3.594953e-5
GO:0070555	response to interleukin-1	3.660433e-5
GO:2000063	positive regulation of ureter smooth muscle cell differentiation	3.753625e-5
GO:2000062	negative regulation of ureter smooth muscle cell differentiation	3.753625e-5
GO:0080125	multicellular structure septum development	3.753625e-5
GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	3.753625e-5
GO:2000357	negative regulation of kidney smooth muscle cell differentiation	3.753625e-5
GO:2000358	positive regulation of kidney smooth muscle cell differentiation	3.753625e-5
GO:0014858	positive regulation of skeletal muscle cell proliferation	3.753625e-5
GO:0007502	digestive tract mesoderm development	3.753625e-5
GO:0060783	mesenchymal smoothened signaling pathway involved in prostate gland development	3.753625e-5
GO:0015874	norepinephrine transport	3.753625e-5
GO:0046534	positive regulation of photoreceptor cell differentiation	3.753625e-5
GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development	3.753625e-5
GO:0001568	blood vessel development	4.102298e-5
GO:0046006	regulation of activated T cell proliferation	4.106568e-5
GO:0060415	muscle tissue morphogenesis	4.193628e-5
GO:0060429	epithelium development	4.349779e-5
GO:0048739	cardiac muscle fiber development	4.398533e-5
GO:0008543	fibroblast growth factor receptor signaling pathway	4.432145e-5
GO:0003127	detection of nodal flow	4.477336e-5
GO:0060081	membrane hyperpolarization	4.477937e-5
GO:0030049	muscle filament sliding	4.515861e-5
GO:0006568	tryptophan metabolic process	4.581301e-5
GO:0055098	response to low-density lipoprotein particle stimulus	4.601278e-5
GO:0006935	chemotaxis	4.706391e-5
GO:0033993	response to lipid	4.914930e-5
GO:0090181	regulation of cholesterol metabolic process	5.112975e-5
GO:0019433	triglyceride catabolic process	5.218072e-5
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	5.254526e-5
GO:0050902	leukocyte adhesive activation	5.254526e-5
GO:0000819	sister chromatid segregation	5.311000e-5
GO:0050868	negative regulation of T cell activation	5.669368e-5
GO:0009226	nucleotide-sugar biosynthetic process	6.223286e-5
GO:0045861	negative regulation of proteolysis	6.327846e-5
GO:0046700	heterocycle catabolic process	6.366746e-5
GO:0048762	mesenchymal cell differentiation	6.478931e-5
GO:0045821	positive regulation of glycolysis	6.490521e-5
GO:0008340	determination of adult lifespan	6.653114e-5
GO:0035909	aorta morphogenesis	6.675797e-5
GO:0001944	vasculature development	6.700215e-5
GO:0003278	apoptosis involved in heart morphogenesis	6.717048e-5
GO:0002041	intussusceptive angiogenesis	6.760380e-5
GO:0006690	icosanoid metabolic process	6.893063e-5
GO:0030225	macrophage differentiation	7.024268e-5
GO:0007155	cell adhesion	7.142857e-5
GO:0060897	neural plate regionalization	7.174872e-5
GO:0006569	tryptophan catabolic process	7.196796e-5
GO:0048732	gland development	7.209754e-5
GO:0000070	mitotic sister chromatid segregation	7.320543e-5
GO:0007076	mitotic chromosome condensation	7.326968e-5
GO:0002092	positive regulation of receptor internalization	7.344453e-5
GO:0046903	secretion	7.358329e-5
GO:0050957	equilibrioception	7.418540e-5
GO:0090022	regulation of neutrophil chemotaxis	7.560954e-5
GO:0006897	endocytosis	7.668989e-5
GO:2000278	regulation of DNA biosynthetic process	7.722696e-5
GO:0033146	regulation of estrogen receptor signaling pathway	7.722696e-5
GO:0051179	localization	7.832110e-5
GO:0010951	negative regulation of endopeptidase activity	8.021834e-5
GO:0021778	oligodendrocyte cell fate specification	8.063742e-5
GO:0044030	regulation of DNA methylation	8.398560e-5
GO:0010172	embryonic body morphogenesis	8.610526e-5
GO:0006972	hyperosmotic response	8.872262e-5
GO:0046483	heterocycle metabolic process	8.932865e-5
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	9.244749e-5
GO:0048864	stem cell development	9.337480e-5
GO:0006952	defense response	9.611140e-5
GO:0007210	serotonin receptor signaling pathway	9.761993e-5
GO:0051347	positive regulation of transferase activity	9.858214e-5
GO:0043547	positive regulation of GTPase activity	1.019755e-4
GO:0006032	chitin catabolic process	1.022046e-4
GO:0042221	response to chemical stimulus	1.022978e-4
GO:0021892	cerebral cortex GABAergic interneuron differentiation	1.066874e-4
GO:0046068	cGMP metabolic process	1.095887e-4
GO:0043367	CD4-positive, alpha-beta T cell differentiation	1.100324e-4
GO:0014032	neural crest cell development	1.102790e-4
GO:0048859	formation of anatomical boundary	1.142811e-4
GO:0015734	taurine transport	1.144130e-4
GO:0060253	negative regulation of glial cell proliferation	1.166068e-4
GO:0030239	myofibril assembly	1.204137e-4
GO:0045214	sarcomere organization	1.216965e-4
GO:0009308	amine metabolic process	1.231850e-4
GO:0045218	zonula adherens maintenance	1.269438e-4
GO:0009726	detection of endogenous stimulus	1.269438e-4
GO:0051549	positive regulation of keratinocyte migration	1.274135e-4
GO:0022612	gland morphogenesis	1.274810e-4
GO:0051345	positive regulation of hydrolase activity	1.318295e-4
GO:0019442	tryptophan catabolic process to acetyl-CoA	1.345950e-4
GO:0003264	regulation of cardioblast proliferation	1.352301e-4
GO:0071954	chemokine (C-C motif) ligand 11 production	1.388988e-4
GO:2000525	positive regulation of T cell costimulation	1.388988e-4
GO:0070086	ubiquitin-dependent endocytosis	1.388988e-4
GO:0035709	memory T cell activation	1.388988e-4
GO:0002215	defense response to nematode	1.388988e-4
GO:0035708	interleukin-4-dependent isotype switching to IgE isotypes	1.388988e-4
GO:0035712	T-helper 2 cell activation	1.388988e-4
GO:0034381	plasma lipoprotein particle clearance	1.408813e-4
GO:0048644	muscle organ morphogenesis	1.447641e-4
GO:0014031	mesenchymal cell development	1.448813e-4
GO:0033559	unsaturated fatty acid metabolic process	1.488102e-4
GO:0048532	anatomical structure arrangement	1.570671e-4
GO:0034374	low-density lipoprotein particle remodeling	1.585253e-4
GO:0051453	regulation of intracellular pH	1.649477e-4
GO:0051541	elastin metabolic process	1.654297e-4
GO:0043534	blood vessel endothelial cell migration	1.677491e-4
GO:0072358	cardiovascular system development	1.688444e-4
GO:0044270	cellular nitrogen compound catabolic process	1.747654e-4
GO:0060463	lung lobe morphogenesis	1.762220e-4
GO:0043491	protein kinase B signaling cascade	1.773888e-4
GO:0003140	determination of left/right asymmetry in lateral mesoderm	1.775673e-4
GO:0016539	intein-mediated protein splicing	1.775673e-4
GO:0045128	negative regulation of reciprocal meiotic recombination	1.780907e-4
GO:0006311	meiotic gene conversion	1.780907e-4
GO:0001932	regulation of protein phosphorylation	1.790135e-4
GO:0006163	purine nucleotide metabolic process	1.831684e-4
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.834489e-4
GO:0006663	platelet activating factor biosynthetic process	1.857327e-4
GO:0055001	muscle cell development	1.869685e-4
GO:0019673	GDP-mannose metabolic process	1.895382e-4
GO:0032796	uropod organization	1.895382e-4
GO:0000086	G2/M transition of mitotic cell cycle	1.909500e-4
GO:0009966	regulation of signal transduction	1.914434e-4
GO:0060459	left lung development	1.923037e-4
GO:0006796	phosphate-containing compound metabolic process	1.970918e-4
GO:0042088	T-helper 1 type immune response	1.971836e-4
GO:0050710	negative regulation of cytokine secretion	1.989929e-4
GO:0006885	regulation of pH	1.990687e-4
GO:0050870	positive regulation of T cell activation	2.000894e-4
GO:0060896	neural plate pattern specification	2.027291e-4
GO:0019216	regulation of lipid metabolic process	2.055611e-4
GO:0009146	purine nucleoside triphosphate catabolic process	2.081524e-4
GO:0009143	nucleoside triphosphate catabolic process	2.158463e-4
GO:0009205	purine ribonucleoside triphosphate metabolic process	2.178511e-4
GO:0043009	chordate embryonic development	2.215361e-4
GO:0048583	regulation of response to stimulus	2.234637e-4
GO:0034720	histone H3-K4 demethylation	2.244643e-4
GO:0044344	cellular response to fibroblast growth factor stimulus	2.276943e-4
GO:0048729	tissue morphogenesis	2.285481e-4
GO:0009207	purine ribonucleoside triphosphate catabolic process	2.292393e-4
GO:0009074	aromatic amino acid family catabolic process	2.297891e-4
GO:0035881	amacrine cell differentiation	2.340097e-4
GO:0045806	negative regulation of endocytosis	2.345514e-4
GO:0007398	ectoderm development	2.413695e-4
GO:0030539	male genitalia development	2.452260e-4
GO:0035378	carbon dioxide transmembrane transport	2.481059e-4
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	2.481059e-4
GO:0035377	transepithelial water transport	2.481059e-4
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	2.481059e-4
GO:0030029	actin filament-based process	2.485767e-4
GO:0006081	cellular aldehyde metabolic process	2.507930e-4
GO:0009199	ribonucleoside triphosphate metabolic process	2.571915e-4
GO:0060485	mesenchyme development	2.582283e-4
GO:0034394	protein localization at cell surface	2.608552e-4
GO:0030162	regulation of proteolysis	2.635848e-4
GO:0031532	actin cytoskeleton reorganization	2.655137e-4
GO:0033089	positive regulation of T cell differentiation in thymus	2.670314e-4
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	2.686186e-4
GO:2000736	regulation of stem cell differentiation	2.715734e-4
GO:0030574	collagen catabolic process	2.728328e-4
GO:2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	2.757222e-4
GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	2.757222e-4
GO:0060302	negative regulation of cytokine activity	2.757222e-4
GO:0070207	protein homotrimerization	2.787613e-4
GO:0048853	forebrain morphogenesis	2.792940e-4
GO:0033273	response to vitamin	2.799692e-4
GO:0001837	epithelial to mesenchymal transition	2.865500e-4
GO:0010573	vascular endothelial growth factor production	2.876750e-4
GO:0032514	positive regulation of protein phosphatase type 2B activity	2.895103e-4
GO:0006468	protein phosphorylation	2.917363e-4
GO:0002376	immune system process	2.958236e-4
GO:0032924	activin receptor signaling pathway	3.046815e-4
GO:0046464	acylglycerol catabolic process	3.098980e-4
GO:0030334	regulation of cell migration	3.107707e-4
GO:0032235	negative regulation of calcium ion transport via store-operated calcium channel activity	3.116700e-4
GO:0010720	positive regulation of cell development	3.122365e-4
GO:0009072	aromatic amino acid family metabolic process	3.192383e-4
GO:0060537	muscle tissue development	3.232214e-4
GO:0007264	small GTPase mediated signal transduction	3.260705e-4
GO:0033189	response to vitamin A	3.290628e-4
GO:0090322	regulation of superoxide metabolic process	3.290841e-4
GO:0048714	positive regulation of oligodendrocyte differentiation	3.290841e-4
GO:0055008	cardiac muscle tissue morphogenesis	3.296540e-4
GO:0060389	pathway-restricted SMAD protein phosphorylation	3.324057e-4
GO:0007042	lysosomal lumen acidification	3.373002e-4
GO:0042776	mitochondrial ATP synthesis coupled proton transport	3.459180e-4
GO:0044243	multicellular organismal catabolic process	3.510225e-4
GO:0030901	midbrain development	3.510989e-4
GO:0006195	purine nucleotide catabolic process	3.542839e-4
GO:0015705	iodide transport	3.617585e-4
GO:0072523	purine-containing compound catabolic process	3.659800e-4
GO:0009792	embryo development ending in birth or egg hatching	3.729747e-4
GO:0016338	calcium-independent cell-cell adhesion	3.730718e-4
GO:0071474	cellular hyperosmotic response	3.815075e-4
GO:0009144	purine nucleoside triphosphate metabolic process	3.866522e-4
GO:0070997	neuron death	3.913615e-4
GO:0055002	striated muscle cell development	3.937359e-4
GO:0090140	regulation of mitochondrial fission	3.944444e-4
GO:0014706	striated muscle tissue development	3.949027e-4
GO:2000304	positive regulation of ceramide biosynthetic process	3.961004e-4
GO:0002248	connective tissue replacement involved in inflammatory response wound healing	3.979666e-4
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	4.078428e-4
GO:0006954	inflammatory response	4.092498e-4
GO:0072521	purine-containing compound metabolic process	4.098851e-4
GO:0007405	neuroblast proliferation	4.125773e-4
GO:0044245	polysaccharide digestion	4.193913e-4
GO:0051257	spindle midzone assembly involved in meiosis	4.304949e-4
GO:0048243	norepinephrine secretion	4.304949e-4
GO:0007060	male meiosis chromosome segregation	4.304949e-4
GO:0042789	mRNA transcription from RNA polymerase II promoter	4.419257e-4
GO:0033674	positive regulation of kinase activity	4.429614e-4
GO:0070848	response to growth factor stimulus	4.438367e-4
GO:0007163	establishment or maintenance of cell polarity	4.476805e-4
GO:0010734	negative regulation of protein glutathionylation	4.516526e-4
GO:0045851	pH reduction	4.537704e-4
GO:0002906	negative regulation of mature B cell apoptosis	4.539080e-4
GO:0032940	secretion by cell	4.548803e-4
GO:0071363	cellular response to growth factor stimulus	4.612144e-4
GO:0055093	response to hyperoxia	4.644862e-4
GO:0009605	response to external stimulus	4.801861e-4
GO:0007228	positive regulation of hh target transcription factor activity	5.050173e-4
GO:0044106	cellular amine metabolic process	5.062680e-4
GO:0031295	T cell costimulation	5.122497e-4
GO:0006955	immune response	5.170975e-4
GO:0044093	positive regulation of molecular function	5.201098e-4
GO:0010001	glial cell differentiation	5.324991e-4
GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	5.463282e-4
GO:0072203	cell proliferation involved in metanephros development	5.533757e-4
GO:0071705	nitrogen compound transport	5.687298e-4
GO:0046503	glycerolipid catabolic process	5.768204e-4
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	5.793592e-4
GO:0010960	magnesium ion homeostasis	5.868946e-4
GO:0006887	exocytosis	5.882307e-4
GO:0045860	positive regulation of protein kinase activity	5.957875e-4
GO:0048565	digestive tract development	5.963197e-4
GO:0016446	somatic hypermutation of immunoglobulin genes	6.144508e-4
GO:0072593	reactive oxygen species metabolic process	6.235762e-4
GO:0070327	thyroid hormone transport	6.259992e-4
GO:0015816	glycine transport	6.313967e-4
GO:0021999	neural plate anterior/posterior regionalization	6.497432e-4
GO:0060837	blood vessel endothelial cell differentiation	6.501085e-4
GO:0060133	somatotropin secreting cell development	6.501085e-4
GO:0042325	regulation of phosphorylation	6.555290e-4
GO:0070946	neutrophil mediated killing of gram-positive bacterium	6.732974e-4
GO:0051452	intracellular pH reduction	6.750331e-4
GO:0071396	cellular response to lipid	6.875042e-4
GO:0042063	gliogenesis	6.940953e-4
GO:0006436	tryptophanyl-tRNA aminoacylation	6.945599e-4
GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	6.945599e-4
GO:0001516	prostaglandin biosynthetic process	6.948076e-4
GO:0051084	'de novo' posttranslational protein folding	6.960116e-4
GO:0061351	neural precursor cell proliferation	7.071912e-4
GO:0048305	immunoglobulin secretion	7.146528e-4
GO:0033124	regulation of GTP catabolic process	7.221510e-4
GO:0030855	epithelial cell differentiation	7.291875e-4
GO:0048731	system development	7.337193e-4
GO:0051146	striated muscle cell differentiation	7.386861e-4
GO:0071470	cellular response to osmotic stress	7.419783e-4
GO:0009166	nucleotide catabolic process	7.575939e-4
GO:0022607	cellular component assembly	7.623929e-4
GO:0014902	myotube differentiation	7.666791e-4
GO:0006982	response to lipid hydroperoxide	7.739379e-4
GO:0042482	positive regulation of odontogenesis	7.771891e-4
GO:0048522	positive regulation of cellular process	7.776877e-4
GO:0055067	monovalent inorganic cation homeostasis	7.782858e-4
GO:2000573	positive regulation of DNA biosynthetic process	7.783839e-4
GO:0046329	negative regulation of JNK cascade	7.804690e-4
GO:0016198	axon choice point recognition	8.056352e-4
GO:0060447	bud outgrowth involved in lung branching	8.068925e-4
GO:0035914	skeletal muscle cell differentiation	8.070366e-4
GO:0051094	positive regulation of developmental process	8.095869e-4
GO:0044255	cellular lipid metabolic process	8.185138e-4
GO:2000145	regulation of cell motility	8.220385e-4
GO:0031557	induction of programmed cell death in response to chemical stimulus	8.222946e-4
GO:0051685	maintenance of ER location	8.310274e-4
GO:0045616	regulation of keratinocyte differentiation	8.367350e-4
GO:0003357	noradrenergic neuron differentiation	8.415721e-4
GO:0032602	chemokine production	8.428788e-4
GO:0070101	positive regulation of chemokine-mediated signaling pathway	8.473777e-4
GO:0046890	regulation of lipid biosynthetic process	8.539165e-4
GO:0006816	calcium ion transport	8.560921e-4
GO:0009150	purine ribonucleotide metabolic process	8.584458e-4
GO:0006360	transcription from RNA polymerase I promoter	8.662709e-4
GO:0034655	nucleobase-containing compound catabolic process	8.811207e-4
GO:0031399	regulation of protein modification process	9.030216e-4
GO:0035295	tube development	9.318793e-4
GO:0014896	muscle hypertrophy	9.384827e-4
GO:0045343	regulation of MHC class I biosynthetic process	9.384827e-4
GO:0046532	regulation of photoreceptor cell differentiation	9.496774e-4
GO:2000303	regulation of ceramide biosynthetic process	9.612115e-4
GO:0090308	regulation of methylation-dependent chromatin silencing	9.612115e-4
GO:0051224	negative regulation of protein transport	9.670919e-4
GO:0006461	protein complex assembly	9.815826e-4
GO:0070933	histone H4 deacetylation	1.017291e-3
GO:0009141	nucleoside triphosphate metabolic process	1.030605e-3
GO:0042942	D-serine transport	1.036882e-3
GO:0048259	regulation of receptor-mediated endocytosis	1.041843e-3
GO:0048854	brain morphogenesis	1.043323e-3
GO:0009719	response to endogenous stimulus	1.046072e-3
GO:0071888	macrophage apoptosis	1.046072e-3
GO:0009298	GDP-mannose biosynthetic process	1.046072e-3
GO:0001934	positive regulation of protein phosphorylation	1.048065e-3
GO:0002090	regulation of receptor internalization	1.053184e-3
GO:0002540	leukotriene production involved in inflammatory response	1.055764e-3
GO:0065009	regulation of molecular function	1.083073e-3
GO:0007265	Ras protein signal transduction	1.106275e-3
GO:0009117	nucleotide metabolic process	1.120617e-3
GO:0061035	regulation of cartilage development	1.124207e-3
GO:0007525	somatic muscle development	1.127599e-3
GO:2000974	negative regulation of pro-B cell differentiation	1.131477e-3
GO:0070271	protein complex biogenesis	1.141351e-3
GO:0043266	regulation of potassium ion transport	1.147920e-3
GO:0043060	meiotic metaphase I plate congression	1.152695e-3
GO:0055086	nucleobase-containing small molecule metabolic process	1.161728e-3
GO:2000121	regulation of removal of superoxide radicals	1.162290e-3
GO:0030818	negative regulation of cAMP biosynthetic process	1.162624e-3
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	1.171864e-3
GO:0048683	regulation of collateral sprouting of intact axon in response to injury	1.179165e-3
GO:0032320	positive regulation of Ras GTPase activity	1.181942e-3
GO:0060413	atrial septum morphogenesis	1.197013e-3
GO:0006691	leukotriene metabolic process	1.206430e-3
GO:0030036	actin cytoskeleton organization	1.214057e-3
GO:0019370	leukotriene biosynthetic process	1.217981e-3
GO:0042692	muscle cell differentiation	1.218090e-3
GO:0014033	neural crest cell differentiation	1.218554e-3
GO:0051051	negative regulation of transport	1.226291e-3
GO:0010676	positive regulation of cellular carbohydrate metabolic process	1.229929e-3
GO:0060251	regulation of glial cell proliferation	1.234659e-3
GO:0046469	platelet activating factor metabolic process	1.242456e-3
GO:0033629	negative regulation of cell adhesion mediated by integrin	1.243994e-3
GO:0048878	chemical homeostasis	1.255072e-3
GO:0009154	purine ribonucleotide catabolic process	1.262680e-3
GO:0043087	regulation of GTPase activity	1.268364e-3
GO:0072134	nephrogenic mesenchyme morphogenesis	1.273308e-3
GO:0030641	regulation of cellular pH	1.281564e-3
GO:0006458	'de novo' protein folding	1.284038e-3
GO:0002026	regulation of the force of heart contraction	1.288428e-3
GO:0008016	regulation of heart contraction	1.301418e-3
GO:0030155	regulation of cell adhesion	1.302456e-3
GO:2000353	positive regulation of endothelial cell apoptosis	1.303779e-3
GO:0002238	response to molecule of fungal origin	1.318536e-3
GO:0032502	developmental process	1.324015e-3

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0051346	negative regulation of hydrolase activity	5.721657e-11
GO:0002579	positive regulation of antigen processing and presentation	2.970925e-10
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	1.272134e-9
GO:0010466	negative regulation of peptidase activity	2.059116e-9
GO:0007601	visual perception	4.169897e-9
GO:0050953	sensory perception of light stimulus	8.107006e-9
GO:0002577	regulation of antigen processing and presentation	8.425841e-9
GO:0051602	response to electrical stimulus	2.165667e-8
GO:0030048	actin filament-based movement	3.209280e-8
GO:0033275	actin-myosin filament sliding	6.581786e-8
GO:0006360	transcription from RNA polymerase I promoter	7.361138e-8
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	8.766894e-8
GO:0030252	growth hormone secretion	1.077367e-7
GO:0002604	regulation of dendritic cell antigen processing and presentation	1.242994e-7
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.369540e-7
GO:0032940	secretion by cell	2.564236e-7
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	3.194727e-7
GO:0070252	actin-mediated cell contraction	3.635842e-7
GO:0010900	negative regulation of phosphatidylcholine catabolic process	4.037013e-7
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	9.042332e-7
GO:0046903	secretion	9.634966e-7
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	1.258774e-6
GO:0001938	positive regulation of endothelial cell proliferation	1.314952e-6
GO:0051336	regulation of hydrolase activity	2.038399e-6
GO:0032642	regulation of chemokine production	2.244206e-6
GO:0046879	hormone secretion	2.519078e-6
GO:0006756	AMP phosphorylation	2.571881e-6
GO:0045625	regulation of T-helper 1 cell differentiation	3.117558e-6
GO:0051186	cofactor metabolic process	3.326942e-6
GO:0045076	regulation of interleukin-2 biosynthetic process	3.511109e-6
GO:0006703	estrogen biosynthetic process	3.860967e-6
GO:0002825	regulation of T-helper 1 type immune response	4.646932e-6
GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	4.902616e-6
GO:0030198	extracellular matrix organization	5.875436e-6
GO:0060192	negative regulation of lipase activity	6.026498e-6
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	6.230170e-6
GO:0010811	positive regulation of cell-substrate adhesion	6.319750e-6
GO:0008615	pyridoxine biosynthetic process	6.418994e-6
GO:0009914	hormone transport	6.802806e-6
GO:0030072	peptide hormone secretion	6.933769e-6
GO:0002790	peptide secretion	7.272748e-6
GO:0010817	regulation of hormone levels	9.644337e-6
GO:0006732	coenzyme metabolic process	9.682648e-6
GO:0009582	detection of abiotic stimulus	9.692034e-6
GO:0002444	myeloid leukocyte mediated immunity	1.052919e-5
GO:0031290	retinal ganglion cell axon guidance	1.064780e-5
GO:0035881	amacrine cell differentiation	1.193962e-5
GO:0052547	regulation of peptidase activity	1.207018e-5
GO:0050848	regulation of calcium-mediated signaling	1.231576e-5
GO:0050663	cytokine secretion	1.314441e-5
GO:0006700	C21-steroid hormone biosynthetic process	1.314441e-5
GO:0050862	positive regulation of T cell receptor signaling pathway	1.406507e-5
GO:0046952	ketone body catabolic process	1.430656e-5
GO:0046940	nucleoside monophosphate phosphorylation	1.430656e-5
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	1.443058e-5
GO:0032722	positive regulation of chemokine production	1.575114e-5
GO:0071299	cellular response to vitamin A	1.731347e-5
GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity	1.855210e-5
GO:0045624	positive regulation of T-helper cell differentiation	1.860825e-5
GO:0071827	plasma lipoprotein particle organization	1.894066e-5
GO:2000107	negative regulation of leukocyte apoptosis	1.896163e-5
GO:0006760	folic acid-containing compound metabolic process	1.958729e-5
GO:0046033	AMP metabolic process	2.045812e-5
GO:0042558	pteridine-containing compound metabolic process	2.194385e-5
GO:0030049	muscle filament sliding	2.274342e-5
GO:0008203	cholesterol metabolic process	2.400698e-5
GO:0006695	cholesterol biosynthetic process	2.592342e-5
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	2.633226e-5
GO:0055014	atrial cardiac muscle cell development	3.006835e-5
GO:0045582	positive regulation of T cell differentiation	3.031048e-5
GO:0032836	glomerular basement membrane development	3.161195e-5
GO:0002551	mast cell chemotaxis	3.324632e-5
GO:0003029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	3.324632e-5
GO:0001516	prostaglandin biosynthetic process	3.421392e-5
GO:0045626	negative regulation of T-helper 1 cell differentiation	3.428078e-5
GO:0048070	regulation of developmental pigmentation	3.745571e-5
GO:0008202	steroid metabolic process	4.061461e-5
GO:0048260	positive regulation of receptor-mediated endocytosis	4.157315e-5
GO:0090023	positive regulation of neutrophil chemotaxis	4.281248e-5
GO:0006600	creatine metabolic process	4.410350e-5
GO:0006694	steroid biosynthetic process	4.903453e-5
GO:0090022	regulation of neutrophil chemotaxis	5.466003e-5
GO:0033239	negative regulation of cellular amine metabolic process	5.537669e-5
GO:0048259	regulation of receptor-mediated endocytosis	5.622114e-5
GO:0007033	vacuole organization	5.672422e-5
GO:0071300	cellular response to retinoic acid	5.851914e-5
GO:0032094	response to food	5.927250e-5
GO:0021542	dentate gyrus development	6.337728e-5
GO:0005981	regulation of glycogen catabolic process	6.659488e-5
GO:0055114	oxidation-reduction process	6.844544e-5
GO:0007600	sensory perception	6.954497e-5
GO:0060377	negative regulation of mast cell differentiation	7.142983e-5
GO:0072355	histone H3-T3 phosphorylation	7.184523e-5
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	7.221143e-5
GO:0045621	positive regulation of lymphocyte differentiation	7.289519e-5
GO:0002027	regulation of heart rate	7.307213e-5
GO:0061014	positive regulation of mRNA catabolic process	7.758699e-5
GO:0040017	positive regulation of locomotion	8.018887e-5
GO:0043163	cell envelope organization	8.177701e-5
GO:0033344	cholesterol efflux	8.296395e-5
GO:2000147	positive regulation of cell motility	8.603333e-5
GO:0007154	cell communication	8.711197e-5
GO:0051272	positive regulation of cellular component movement	9.168520e-5
GO:0006936	muscle contraction	9.268941e-5
GO:0009583	detection of light stimulus	9.781539e-5
GO:0042823	pyridoxal phosphate biosynthetic process	9.857482e-5
GO:0071460	cellular response to cell-matrix adhesion	9.857482e-5
GO:0044058	regulation of digestive system process	1.015961e-4
GO:0048739	cardiac muscle fiber development	1.024662e-4
GO:0044255	cellular lipid metabolic process	1.107892e-4
GO:0097022	lymphocyte migration into lymph node	1.111412e-4
GO:0072610	interleukin-12 secretion	1.111412e-4
GO:0032509	endosome transport via multivesicular body sorting pathway	1.120959e-4
GO:0002885	positive regulation of hypersensitivity	1.162026e-4
GO:0002478	antigen processing and presentation of exogenous peptide antigen	1.176655e-4
GO:0035813	regulation of renal sodium excretion	1.278780e-4
GO:0016125	sterol metabolic process	1.379704e-4
GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	1.420173e-4
GO:0032464	positive regulation of protein homooligomerization	1.423589e-4
GO:0009581	detection of external stimulus	1.435119e-4
GO:0015833	peptide transport	1.533293e-4
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	1.582495e-4
GO:0034765	regulation of ion transmembrane transport	1.599118e-4
GO:0032412	regulation of ion transmembrane transporter activity	1.604950e-4
GO:0001954	positive regulation of cell-matrix adhesion	1.620035e-4
GO:0060021	palate development	1.643500e-4
GO:0006422	aspartyl-tRNA aminoacylation	1.670868e-4
GO:0032205	negative regulation of telomere maintenance	1.731230e-4
GO:0097026	dendritic cell dendrite assembly	1.752436e-4
GO:0051103	DNA ligation involved in DNA repair	1.767270e-4
GO:0043086	negative regulation of catalytic activity	1.828929e-4
GO:0060696	regulation of phospholipid catabolic process	1.830822e-4
GO:0060318	definitive erythrocyte differentiation	1.868220e-4
GO:0022898	regulation of transmembrane transporter activity	1.906893e-4
GO:0006629	lipid metabolic process	1.915651e-4
GO:0050870	positive regulation of T cell activation	2.063875e-4
GO:0060296	regulation of cilium beat frequency involved in ciliary motility	2.120642e-4
GO:0019884	antigen processing and presentation of exogenous antigen	2.124040e-4
GO:0071295	cellular response to vitamin	2.153484e-4
GO:0033299	secretion of lysosomal enzymes	2.182151e-4
GO:0006637	acyl-CoA metabolic process	2.197649e-4
GO:0023052	signaling	2.332713e-4
GO:0032873	negative regulation of stress-activated MAPK cascade	2.384288e-4
GO:0032663	regulation of interleukin-2 production	2.418504e-4
GO:0060730	regulation of intestinal epithelial structure maintenance	2.442692e-4
GO:0035883	enteroendocrine cell differentiation	2.442692e-4
GO:0042446	hormone biosynthetic process	2.549500e-4
GO:0051769	regulation of nitric-oxide synthase biosynthetic process	2.603215e-4
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	2.613022e-4
GO:0048245	eosinophil chemotaxis	2.677784e-4
GO:0006954	inflammatory response	2.757051e-4
GO:0060154	cellular process regulating host cell cycle in response to virus	2.823985e-4
GO:0090196	regulation of chemokine secretion	2.827532e-4
GO:0014866	skeletal myofibril assembly	2.905027e-4
GO:0065009	regulation of molecular function	2.909312e-4
GO:0045622	regulation of T-helper cell differentiation	2.914577e-4
GO:0045086	positive regulation of interleukin-2 biosynthetic process	2.985792e-4
GO:0006549	isoleucine metabolic process	3.016203e-4
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	3.105417e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	3.109908e-4
GO:0030335	positive regulation of cell migration	3.255029e-4
GO:0006705	mineralocorticoid biosynthetic process	3.468540e-4
GO:0034447	very-low-density lipoprotein particle clearance	3.476893e-4
GO:0007040	lysosome organization	3.544691e-4
GO:0048747	muscle fiber development	3.741836e-4
GO:0034377	plasma lipoprotein particle assembly	3.761725e-4
GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	3.788160e-4
GO:0010876	lipid localization	3.880315e-4
GO:0045580	regulation of T cell differentiation	3.910587e-4
GO:0031929	TOR signaling cascade	3.977979e-4
GO:0035584	calcium-mediated signaling using intracellular calcium source	3.978719e-4
GO:0034614	cellular response to reactive oxygen species	4.101296e-4
GO:0006887	exocytosis	4.149743e-4
GO:0006436	tryptophanyl-tRNA aminoacylation	4.198050e-4
GO:0032966	negative regulation of collagen biosynthetic process	4.233450e-4
GO:0003329	pancreatic PP cell fate commitment	4.233450e-4
GO:0003326	pancreatic A cell fate commitment	4.233450e-4
GO:0051610	serotonin uptake	4.332024e-4
GO:0055098	response to low-density lipoprotein particle stimulus	4.396780e-4
GO:0051208	sequestering of calcium ion	4.469593e-4
GO:0009236	cobalamin biosynthetic process	4.469593e-4
GO:0045575	basophil activation	4.469593e-4
GO:0050850	positive regulation of calcium-mediated signaling	4.659630e-4
GO:0016226	iron-sulfur cluster assembly	4.811729e-4
GO:0019054	modulation by virus of host cellular process	4.839746e-4
GO:0050920	regulation of chemotaxis	4.858278e-4
GO:0070244	negative regulation of thymocyte apoptosis	4.873403e-4
GO:0055008	cardiac muscle tissue morphogenesis	5.045984e-4
GO:0008210	estrogen metabolic process	5.202518e-4
GO:0070229	negative regulation of lymphocyte apoptosis	5.234667e-4
GO:0006103	2-oxoglutarate metabolic process	5.297941e-4
GO:0000103	sulfate assimilation	5.490757e-4
GO:0032469	endoplasmic reticulum calcium ion homeostasis	5.534740e-4
GO:0006869	lipid transport	5.559573e-4
GO:0097006	regulation of plasma lipoprotein particle levels	5.664430e-4
GO:0009612	response to mechanical stimulus	5.757542e-4
GO:0035964	COPI-coated vesicle budding	5.764819e-4
GO:0007522	visceral muscle development	5.827031e-4
GO:0007186	G-protein coupled receptor protein signaling pathway	5.942699e-4
GO:0042744	hydrogen peroxide catabolic process	5.990527e-4
GO:0070302	regulation of stress-activated protein kinase signaling cascade	6.006162e-4
GO:0035315	hair cell differentiation	6.094724e-4
GO:0050790	regulation of catalytic activity	6.200628e-4
GO:0002649	regulation of tolerance induction to self antigen	6.258684e-4
GO:0042364	water-soluble vitamin biosynthetic process	6.259054e-4
GO:0051929	positive regulation of calcium ion transport via voltage-gated calcium channel activity	6.281989e-4
GO:0055002	striated muscle cell development	6.387504e-4
GO:0001961	positive regulation of cytokine-mediated signaling pathway	6.423498e-4
GO:0016322	neuron remodeling	6.672441e-4
GO:0006767	water-soluble vitamin metabolic process	6.703745e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	6.760624e-4
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	6.790156e-4
GO:0070301	cellular response to hydrogen peroxide	7.131207e-4
GO:0032409	regulation of transporter activity	7.162032e-4
GO:0007602	phototransduction	7.185950e-4
GO:0002830	positive regulation of type 2 immune response	7.207533e-4
GO:0045576	mast cell activation	7.303584e-4
GO:0050863	regulation of T cell activation	7.512042e-4
GO:0031670	cellular response to nutrient	7.788260e-4
GO:0055001	muscle cell development	7.803836e-4
GO:0051716	cellular response to stimulus	7.825171e-4
GO:0006631	fatty acid metabolic process	7.923473e-4
GO:0051188	cofactor biosynthetic process	7.962142e-4
GO:0050921	positive regulation of chemotaxis	8.046986e-4
GO:0016192	vesicle-mediated transport	8.097573e-4
GO:0002828	regulation of type 2 immune response	8.229749e-4
GO:0002443	leukocyte mediated immunity	8.720945e-4
GO:0007214	gamma-aminobutyric acid signaling pathway	8.883478e-4
GO:0030916	otic vesicle formation	8.947825e-4
GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	9.086843e-4
GO:0032204	regulation of telomere maintenance	9.086843e-4
GO:0030240	skeletal muscle thin filament assembly	9.224403e-4
GO:0016126	sterol biosynthetic process	9.291154e-4
GO:0010834	telomere maintenance via telomere shortening	9.379276e-4
GO:0048738	cardiac muscle tissue development	9.381055e-4
GO:0015837	amine transport	9.550189e-4
GO:0051894	positive regulation of focal adhesion assembly	9.841470e-4
GO:0035814	negative regulation of renal sodium excretion	9.845404e-4
GO:0034379	very-low-density lipoprotein particle assembly	1.015780e-3
GO:0032765	positive regulation of mast cell cytokine production	1.023136e-3
GO:0015677	copper ion import	1.023136e-3
GO:0060003	copper ion export	1.023136e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.023136e-3
GO:0002431	Fc receptor mediated stimulatory signaling pathway	1.023136e-3
GO:0034695	response to prostaglandin E stimulus	1.047095e-3
GO:0006266	DNA ligation	1.047095e-3
GO:0044062	regulation of excretion	1.054137e-3
GO:0002446	neutrophil mediated immunity	1.055755e-3
GO:0003012	muscle system process	1.068811e-3
GO:0042840	D-glucuronate catabolic process	1.072149e-3
GO:0006693	prostaglandin metabolic process	1.112222e-3
GO:0016049	cell growth	1.116076e-3
GO:0010951	negative regulation of endopeptidase activity	1.118900e-3
GO:0000724	double-strand break repair via homologous recombination	1.154124e-3
GO:0071257	cellular response to electrical stimulus	1.190442e-3
GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	1.220772e-3
GO:0045581	negative regulation of T cell differentiation	1.229554e-3
GO:0050896	response to stimulus	1.240636e-3
GO:0032615	interleukin-12 production	1.302746e-3
GO:0033700	phospholipid efflux	1.309011e-3
GO:0009605	response to external stimulus	1.367573e-3
GO:0060907	positive regulation of macrophage cytokine production	1.367929e-3
GO:0032229	negative regulation of synaptic transmission, GABAergic	1.372102e-3
GO:0030239	myofibril assembly	1.405064e-3
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1.423046e-3
GO:0007512	adult heart development	1.424458e-3
GO:0046638	positive regulation of alpha-beta T cell differentiation	1.475846e-3
GO:0045619	regulation of lymphocyte differentiation	1.485509e-3
GO:0051005	negative regulation of lipoprotein lipase activity	1.522632e-3
GO:0034382	chylomicron remnant clearance	1.522632e-3
GO:0034097	response to cytokine stimulus	1.531375e-3
GO:0042743	hydrogen peroxide metabolic process	1.534042e-3
GO:0048633	positive regulation of skeletal muscle tissue growth	1.534235e-3
GO:2000412	positive regulation of thymocyte migration	1.542518e-3
GO:0002518	lymphocyte chemotaxis across high endothelial venule	1.542518e-3
GO:0060760	positive regulation of response to cytokine stimulus	1.545593e-3
GO:0002376	immune system process	1.550866e-3
GO:0023061	signal release	1.568142e-3
GO:0000302	response to reactive oxygen species	1.580566e-3
GO:0007165	signal transduction	1.606152e-3
GO:0072171	mesonephric tubule morphogenesis	1.610554e-3
GO:0045785	positive regulation of cell adhesion	1.613442e-3
GO:0060415	muscle tissue morphogenesis	1.620954e-3
GO:0065005	protein-lipid complex assembly	1.634412e-3
GO:0045055	regulated secretory pathway	1.642406e-3
GO:0010388	cullin deneddylation	1.650777e-3
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	1.692994e-3
GO:2000505	regulation of energy homeostasis	1.701001e-3
GO:0009108	coenzyme biosynthetic process	1.709950e-3
GO:0042832	defense response to protozoan	1.710822e-3
GO:0010984	regulation of lipoprotein particle clearance	1.771491e-3
GO:0042074	cell migration involved in gastrulation	1.777287e-3
GO:0002274	myeloid leukocyte activation	1.780021e-3
GO:0070254	mucus secretion	1.788027e-3
GO:0009949	polarity specification of anterior/posterior axis	1.788027e-3
GO:0008610	lipid biosynthetic process	1.843610e-3
GO:0031448	positive regulation of fast-twitch skeletal muscle fiber contraction	1.868203e-3
GO:0043201	response to leucine	1.869974e-3
GO:0002528	regulation of vascular permeability involved in acute inflammatory response	1.869974e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	1.881087e-3
GO:0034435	cholesterol esterification	1.883274e-3
GO:0046328	regulation of JNK cascade	1.909934e-3
GO:0009306	protein secretion	1.930188e-3
GO:0043583	ear development	1.986181e-3
GO:0070371	ERK1 and ERK2 cascade	1.990210e-3
GO:0003188	heart valve formation	2.023215e-3
GO:0071345	cellular response to cytokine stimulus	2.033276e-3
GO:0045766	positive regulation of angiogenesis	2.041470e-3
GO:0048534	hemopoietic or lymphoid organ development	2.043855e-3
GO:0045627	positive regulation of T-helper 1 cell differentiation	2.049534e-3
GO:0006101	citrate metabolic process	2.049534e-3
GO:0000725	recombinational repair	2.056537e-3
GO:0006288	base-excision repair, DNA ligation	2.132921e-3
GO:0045630	positive regulation of T-helper 2 cell differentiation	2.132921e-3
GO:0030073	insulin secretion	2.160777e-3
GO:0042264	peptidyl-aspartic acid hydroxylation	2.170800e-3
GO:0014057	positive regulation of acetylcholine secretion	2.170800e-3
GO:0048644	muscle organ morphogenesis	2.189159e-3
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	2.194057e-3
GO:2000737	negative regulation of stem cell differentiation	2.204713e-3
GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	2.204713e-3
GO:0032682	negative regulation of chemokine production	2.204713e-3
GO:0046884	follicle-stimulating hormone secretion	2.231916e-3
GO:0032275	luteinizing hormone secretion	2.231916e-3
GO:0050679	positive regulation of epithelial cell proliferation	2.233484e-3
GO:0050770	regulation of axonogenesis	2.265912e-3
GO:0043506	regulation of JUN kinase activity	2.268144e-3
GO:0061013	regulation of mRNA catabolic process	2.275002e-3
GO:0032461	positive regulation of protein oligomerization	2.275002e-3
GO:0032375	negative regulation of cholesterol transport	2.283534e-3
GO:0045022	early endosome to late endosome transport	2.297591e-3
GO:0060259	regulation of feeding behavior	2.308751e-3
GO:0072028	nephron morphogenesis	2.353542e-3
GO:0009743	response to carbohydrate stimulus	2.354371e-3
GO:0046637	regulation of alpha-beta T cell differentiation	2.409071e-3
GO:0065007	biological regulation	2.437296e-3
GO:0006601	creatine biosynthetic process	2.480571e-3
GO:0050849	negative regulation of calcium-mediated signaling	2.554764e-3
GO:0043303	mast cell degranulation	2.568609e-3
GO:0010985	negative regulation of lipoprotein particle clearance	2.625683e-3
GO:0034612	response to tumor necrosis factor	2.627890e-3
GO:0050900	leukocyte migration	2.638476e-3
GO:0072428	signal transduction involved in intra-S DNA damage checkpoint	2.654866e-3
GO:0071638	negative regulation of monocyte chemotactic protein-1 production	2.654866e-3
GO:2000429	negative regulation of neutrophil aggregation	2.654866e-3
GO:2000469	negative regulation of peroxidase activity	2.654866e-3
GO:0035726	common myeloid progenitor cell proliferation	2.654866e-3
GO:0043633	polyadenylation-dependent RNA catabolic process	2.654866e-3
GO:0002561	basophil degranulation	2.654866e-3
GO:0018916	nitrobenzene metabolic process	2.654866e-3
GO:0045806	negative regulation of endocytosis	2.663709e-3
GO:0032075	positive regulation of nuclease activity	2.686640e-3
GO:0018094	protein polyglycylation	2.719591e-3
GO:0045085	negative regulation of interleukin-2 biosynthetic process	2.749231e-3
GO:0002520	immune system development	2.753729e-3
GO:0030154	cell differentiation	2.773516e-3
GO:0042476	odontogenesis	2.838009e-3
GO:0060326	cell chemotaxis	2.844515e-3
GO:0048588	developmental cell growth	2.859143e-3
GO:0070670	response to interleukin-4	2.904336e-3
GO:0050908	detection of light stimulus involved in visual perception	2.926394e-3
GO:0045722	positive regulation of gluconeogenesis	2.931799e-3
GO:0043089	positive regulation of Cdc42 GTPase activity	2.942107e-3
GO:0034369	plasma lipoprotein particle remodeling	3.038061e-3
GO:0010758	regulation of macrophage chemotaxis	3.096934e-3
GO:0002883	regulation of hypersensitivity	3.096934e-3
GO:0007032	endosome organization	3.097202e-3
GO:0071733	transcriptional activation by promoter-enhancer looping	3.099128e-3
GO:0032211	negative regulation of telomere maintenance via telomerase	3.099128e-3
GO:0033238	regulation of cellular amine metabolic process	3.101322e-3
GO:0006573	valine metabolic process	3.107925e-3
GO:0046449	creatinine metabolic process	3.157003e-3
GO:0048563	post-embryonic organ morphogenesis	3.317839e-3
GO:0043482	cellular pigment accumulation	3.351579e-3
GO:0045989	positive regulation of striated muscle contraction	3.370386e-3
GO:0080135	regulation of cellular response to stress	3.377905e-3
GO:0070509	calcium ion import	3.396794e-3
GO:0035809	regulation of urine volume	3.396794e-3
GO:0021562	vestibulocochlear nerve development	3.423891e-3
GO:0044092	negative regulation of molecular function	3.429545e-3
GO:0090197	positive regulation of chemokine secretion	3.488916e-3
GO:0071637	regulation of monocyte chemotactic protein-1 production	3.530747e-3
GO:0032374	regulation of cholesterol transport	3.538710e-3
GO:0051549	positive regulation of keratinocyte migration	3.546013e-3
GO:0007289	spermatid nucleus differentiation	3.556503e-3
GO:0034762	regulation of transmembrane transport	3.683811e-3
GO:0030097	hemopoiesis	3.685158e-3
GO:0071402	cellular response to lipoprotein particle stimulus	3.775976e-3
GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	3.855722e-3
GO:0090076	relaxation of skeletal muscle	3.855722e-3
GO:0032470	elevation of endoplasmic reticulum calcium ion concentration	3.855722e-3
GO:0006337	nucleosome disassembly	3.855722e-3
GO:0048843	negative regulation of axon extension involved in axon guidance	3.861507e-3
GO:0040040	thermosensory behavior	3.908398e-3
GO:0051126	negative regulation of actin nucleation	3.908398e-3
GO:0006499	N-terminal protein myristoylation	3.908398e-3
GO:0060971	embryonic heart tube left/right pattern formation	4.018484e-3
GO:0006507	GPI anchor release	4.018484e-3
GO:0071702	organic substance transport	4.091210e-3
GO:0072172	mesonephric tubule formation	4.092363e-3
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	4.092363e-3
GO:0007166	cell surface receptor linked signaling pathway	4.115953e-3
GO:2000253	positive regulation of feeding behavior	4.143168e-3
GO:2000507	positive regulation of energy homeostasis	4.143168e-3
GO:0046950	cellular ketone body metabolic process	4.143168e-3
GO:0042976	activation of Janus kinase activity	4.143168e-3
GO:0051954	positive regulation of amine transport	4.191370e-3
GO:0060932	His-Purkinje system cell differentiation	4.261116e-3
GO:0060926	pacemaker cell development	4.261116e-3
GO:0006868	glutamine transport	4.263936e-3
GO:0006903	vesicle targeting	4.271211e-3
GO:0072088	nephron epithelium morphogenesis	4.286364e-3
GO:0007257	activation of JUN kinase activity	4.338707e-3
GO:0007267	cell-cell signaling	4.378786e-3
GO:0031442	positive regulation of mRNA 3'-end processing	4.378863e-3
GO:0051641	cellular localization	4.378947e-3
GO:0010633	negative regulation of epithelial cell migration	4.379577e-3
GO:0009749	response to glucose stimulus	4.401067e-3
GO:0043269	regulation of ion transport	4.412320e-3
GO:0072087	renal vesicle development	4.447893e-3
GO:0007586	digestion	4.469636e-3
GO:0045765	regulation of angiogenesis	4.470044e-3
GO:0000910	cytokinesis	4.491507e-3
GO:0010759	positive regulation of macrophage chemotaxis	4.564947e-3
GO:0015844	monoamine transport	4.570534e-3
GO:0060920	pacemaker cell differentiation	4.573962e-3
GO:0045931	positive regulation of mitotic cell cycle	4.588820e-3
GO:0002720	positive regulation of cytokine production involved in immune response	4.643552e-3
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	4.670676e-3
GO:0008078	mesodermal cell migration	4.674554e-3
GO:0031346	positive regulation of cell projection organization	4.682439e-3
GO:0031344	regulation of cell projection organization	4.739317e-3
GO:0009303	rRNA transcription	4.752547e-3
GO:0016310	phosphorylation	4.850364e-3
GO:0010761	fibroblast migration	4.853004e-3
GO:0072282	metanephric nephron tubule morphogenesis	4.920585e-3
GO:0010810	regulation of cell-substrate adhesion	4.939273e-3
GO:0031668	cellular response to extracellular stimulus	5.054262e-3
GO:0014832	urinary bladder smooth muscle contraction	5.058712e-3
GO:0031669	cellular response to nutrient levels	5.140990e-3
GO:0042946	glucoside transport	5.161284e-3
GO:0071346	cellular response to interferon-gamma	5.182863e-3
GO:0051094	positive regulation of developmental process	5.351328e-3
GO:0009062	fatty acid catabolic process	5.392168e-3
GO:0060375	regulation of mast cell differentiation	5.441679e-3
GO:0015870	acetylcholine transport	5.441679e-3
GO:0050927	positive regulation of positive chemotaxis	5.450707e-3
GO:0030595	leukocyte chemotaxis	5.595034e-3
GO:2000706	negative regulation of dense core granule biogenesis	5.598741e-3
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	5.598741e-3
GO:2000798	negative regulation of amniotic stem cell differentiation	5.598741e-3
GO:0001309	age-dependent telomere shortening	5.598741e-3
GO:0010085	polarity specification of proximal/distal axis	5.598741e-3
GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	5.598741e-3
GO:0048538	thymus development	5.609329e-3
GO:0014050	negative regulation of glutamate secretion	5.627270e-3
GO:0031576	G2/M transition checkpoint	5.697359e-3
GO:0009235	cobalamin metabolic process	5.707643e-3
GO:0070305	response to cGMP	5.720455e-3
GO:0002331	pre-B cell allelic exclusion	5.720455e-3
GO:0030826	regulation of cGMP biosynthetic process	5.751042e-3
GO:2000736	regulation of stem cell differentiation	5.765543e-3
GO:0050926	regulation of positive chemotaxis	5.817754e-3
GO:0045620	negative regulation of lymphocyte differentiation	5.836413e-3
GO:0070460	thyroid-stimulating hormone secretion	5.844081e-3
GO:0045494	photoreceptor cell maintenance	5.936716e-3
GO:0002021	response to dietary excess	6.039752e-3
GO:0072289	metanephric nephron tubule formation	6.040958e-3
GO:0006829	zinc ion transport	6.044153e-3
GO:0071600	otic vesicle morphogenesis	6.059777e-3
GO:0050995	negative regulation of lipid catabolic process	6.063283e-3
GO:0044242	cellular lipid catabolic process	6.096826e-3
GO:0032103	positive regulation of response to external stimulus	6.132237e-3
GO:0001562	response to protozoan	6.164462e-3
GO:0007613	memory	6.195486e-3
GO:0033059	cellular pigmentation	6.282957e-3
GO:0007182	common-partner SMAD protein phosphorylation	6.335919e-3
GO:0009266	response to temperature stimulus	6.357799e-3
GO:0046634	regulation of alpha-beta T cell activation	6.369076e-3
GO:0043154	negative regulation of caspase activity	6.369076e-3
GO:0048261	negative regulation of receptor-mediated endocytosis	6.433350e-3
GO:0050861	positive regulation of B cell receptor signaling pathway	6.452969e-3
GO:2000189	positive regulation of cholesterol homeostasis	6.452969e-3
GO:0015680	intracellular copper ion transport	6.452969e-3
GO:0045922	negative regulation of fatty acid metabolic process	6.461704e-3
GO:0043129	surfactant homeostasis	6.461704e-3
GO:0072274	metanephric glomerular basement membrane development	6.501132e-3
GO:0090241	negative regulation of histone H4 acetylation	6.501132e-3
GO:0072249	metanephric glomerular visceral epithelial cell development	6.501132e-3
GO:0002542	Factor XII activation	6.501132e-3
GO:0034401	regulation of transcription by chromatin organization	6.501132e-3
GO:0048677	axon extension involved in regeneration	6.501132e-3
GO:0051792	medium-chain fatty acid biosynthetic process	6.501132e-3
GO:0042551	neuron maturation	6.553928e-3
GO:0043029	T cell homeostasis	6.556503e-3
GO:0043507	positive regulation of JUN kinase activity	6.574233e-3
GO:0032825	positive regulation of natural killer cell differentiation	6.595211e-3
GO:0006599	phosphagen metabolic process	6.595211e-3
GO:0032816	positive regulation of natural killer cell activation	6.611947e-3
GO:0002066	columnar/cuboidal epithelial cell development	6.659638e-3