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{{CL
{{CL
|id=CL:0000040
|alt_id=
|name=monoblast
|namespace=cell;;efo
|def="A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." [GOC:add, http://www.clt.astate.edu/wwilliam/, http://www.copewithcytokines.de, PMID:1104740]
|xref=FMA:83553
|is_a=CL:0002194
|synonym="CFU-M" RELATED [];;"colony forming unit macrophage" RELATED [];;"monocyte stem cell" RELATED []
|comment=Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.
|comment=Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." [GOC:add, http://www.clt.astate.edu/wwilliam/, http://www.copewithcytokines.de, PMID:1104740]
|subset=
|derives_from=
|derives_from=
|develops_from=CL:0002009
|develops_from=CL:0002009
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000040
|is_a=CL:0000763 ;;CL:0002194
|is_obsolete=
|located_in=
|located_in=
|name=monoblast
|namespace=cell;;efo
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="CFU-M" RELATED [];;"colony forming unit macrophage" RELATED [];;"monocyte stem cell" RELATED []
|union_of=
|xref=FMA:83553
}}
}}

Revision as of 10:12, 12 September 2014

Name:monoblast
Namespace:cell;;efo
Definition:"A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus." [GOC:add, http://www.clt.astate.edu/wwilliam/, http://www.copewithcytokines.de, PMID:1104740]
Xrefs:
links:
FMA:83553
Synonyms: "CFU-M" RELATED []
"colony forming unit macrophage" RELATED []
"monocyte stem cell" RELATED []
Comments:Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000763(myeloid cell),CL:0002194(monopoietic cell)
develops_from:CL:0002009(macrophage dendritic cell progenitor)



Children


develops from:CL:0000559 (promonocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.



Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000040 (monoblast), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.04e-147FFCP PHASE2:Hg19::chr7:77050554..77050601,+#_102b57f152dc3cb6d15cb4ae40e46f39p@chr7:77050554..77050601, +
1.04e-147FFCP PHASE1:Hg19::chr7:77050554..77050601,+#_102b57f152dc3cb6d15cb4ae40e46f39p@chr7:77050554..77050601, +
5.64e-145FFCP PHASE2:Hg19::chr19:18288651..18288682,+#_59bd3fe86fc67b7fe468dc7f0f2ea18bp5@IFI30
5.64e-145FFCP PHASE1:Hg19::chr19:18288651..18288682,+#_59bd3fe86fc67b7fe468dc7f0f2ea18bp5@IFI30
4.95e-140FFCP PHASE2:Hg19::chr19:18288828..18288861,+#_a36944be3e8bea1bbd3ec01b471937f1p7@IFI30
4.95e-140FFCP PHASE1:Hg19::chr19:18288828..18288861,+#_a36944be3e8bea1bbd3ec01b471937f1p7@IFI30
5.06e-140FFCP PHASE2:Hg19::chr5:180242646..180242657,-#_c41c7f4ffb4814a16b0b6ed50627e88cp15@MGAT1
5.06e-140FFCP PHASE1:Hg19::chr5:180242646..180242657,-#_c41c7f4ffb4814a16b0b6ed50627e88cp15@MGAT1
1.31e-139FFCP PHASE1:Hg19::chr1:161188661..161188679,+#_a3a922caa6095f88eb74a493ef12823ap@chr1:161188661..161188679, +
1.31e-139FFCP PHASE2:Hg19::chr1:161188661..161188679,+#_a3a922caa6095f88eb74a493ef12823ap@chr1:161188661..161188679, +
5.87e-136FFCP PHASE2:Hg19::chr2:38358217..38358244,+#_90a3154d215d0c3cc62fd2684293389bp1@CYP1B1-AS1
5.87e-136FFCP PHASE1:Hg19::chr2:38358217..38358244,+#_90a3154d215d0c3cc62fd2684293389bp1@CYP1B1-AS1
5.37e-135FFCP PHASE1:Hg19::chr4:185314125..185314143,-#_21deb975ec0691e25c3617bd83fb8b24p@chr4:185314125..185314143, -
5.37e-135FFCP PHASE2:Hg19::chr4:185314125..185314143,-#_21deb975ec0691e25c3617bd83fb8b24p@chr4:185314125..185314143, -
3.75e-134FFCP PHASE1:Hg19::chr3:149531627..149531651,+#_3d811ecdbf5fc895479264b703fe4ed1p7@RNF13
3.75e-134FFCP PHASE2:Hg19::chr3:149531627..149531651,+#_3d811ecdbf5fc895479264b703fe4ed1p7@RNF13
6.15e-134FFCP PHASE2:Hg19::chr2:119726719..119726744,+#_70b2dfb839229699dce935e6cb163deep@chr2:119726719..119726744, +
6.15e-134FFCP PHASE1:Hg19::chr2:119726719..119726744,+#_70b2dfb839229699dce935e6cb163deep@chr2:119726719..119726744, +
7.41e-134FFCP PHASE2:Hg19::chr1:161187824..161187847,+#_4741dea864e2b4e65bc8361187188027p@chr1:161187824..161187847, +
7.41e-134FFCP PHASE1:Hg19::chr1:161187824..161187847,+#_4741dea864e2b4e65bc8361187188027p@chr1:161187824..161187847, +
2.24e-133FFCP PHASE2:Hg19::chr17:7482481..7482508,-#_a6e11dd5969514a7fb8ba63d1e778bafp@chr17:7482481..7482508, -
2.24e-133FFCP PHASE1:Hg19::chr17:7482481..7482508,-#_a6e11dd5969514a7fb8ba63d1e778bafp@chr17:7482481..7482508, -
4.55e-133FFCP PHASE1:Hg19::chr19:18286116..18286156,+#_194f003e09b739ceadd46454ed778ff9p@chr19:18286116..18286156, +
4.55e-133FFCP PHASE2:Hg19::chr19:18286116..18286156,+#_194f003e09b739ceadd46454ed778ff9p@chr19:18286116..18286156, +
1.09e-132FFCP PHASE1:Hg19::chr4:185314151..185314178,-#_f977e0db84003918acae04c7d5842a5ep@chr4:185314151..185314178, -
1.09e-132FFCP PHASE2:Hg19::chr4:185314151..185314178,-#_f977e0db84003918acae04c7d5842a5ep@chr4:185314151..185314178, -
1.13e-132FFCP PHASE2:Hg19::chr5:131280548..131280574,-#_06b163e292541b15a2f3beded661dc6ap1@ENST00000425320
1.13e-132FFCP PHASE1:Hg19::chr5:131280548..131280574,-#_06b163e292541b15a2f3beded661dc6ap1@ENST00000425320
1.42e-132FFCP PHASE1:Hg19::chr2:145429606..145429658,+#_afcb2fb18336b8be21837e27df17d9e7p@chr2:145429606..145429658, +
1.42e-132FFCP PHASE2:Hg19::chr2:145429606..145429658,+#_afcb2fb18336b8be21837e27df17d9e7p@chr2:145429606..145429658, +
1.21e-131FFCP PHASE2:Hg19::chr19:18288064..18288080,+#_b3ff82b3177da763bb4ab0017397fbf0p@chr19:18288064..18288080, +
1.21e-131FFCP PHASE1:Hg19::chr19:18288064..18288080,+#_b3ff82b3177da763bb4ab0017397fbf0p@chr19:18288064..18288080, +
2.27e-131FFCP PHASE1:Hg19::chr1:150724282..150724308,-#_40d6f9d99dd17d795ce3dc2f76252548p8@CTSS
2.27e-131FFCP PHASE2:Hg19::chr1:150724282..150724308,-#_40d6f9d99dd17d795ce3dc2f76252548p8@CTSS
2.82e-131FFCP PHASE2:Hg19::chrX:37664331..37664352,+#_2b3290d3e2048a9df7b6cb55975115eap@chrX:37664331..37664352, +
2.82e-131FFCP PHASE1:Hg19::chrX:37664331..37664352,+#_2b3290d3e2048a9df7b6cb55975115eap@chrX:37664331..37664352, +
4.07e-131FFCP PHASE2:Hg19::chr4:185314188..185314207,-#_f7c54edfc067c8cf57396cb5afb1977fp@chr4:185314188..185314207, -
4.07e-131FFCP PHASE1:Hg19::chr4:185314188..185314207,-#_f7c54edfc067c8cf57396cb5afb1977fp@chr4:185314188..185314207, -
5.24e-131FFCP PHASE1:Hg19::chr15:65174546..65174583,-#_c178ca20fec073d75a806659bb85789cp@chr15:65174546..65174583, -
5.24e-131FFCP PHASE2:Hg19::chr15:65174546..65174583,-#_c178ca20fec073d75a806659bb85789cp@chr15:65174546..65174583, -
2.76e-130FFCP PHASE1:Hg19::chr4:159727272..159727307,+#_82adf8437c6556a8cd826df68e568934p7@FNIP2
2.76e-130FFCP PHASE2:Hg19::chr4:159727272..159727307,+#_82adf8437c6556a8cd826df68e568934p7@FNIP2
3.58e-130FFCP PHASE1:Hg19::chr1:161188746..161188758,+#_b66d4803be6314df7a3352a112eeff33p@chr1:161188746..161188758, +
3.58e-130FFCP PHASE2:Hg19::chr1:161188746..161188758,+#_b66d4803be6314df7a3352a112eeff33p@chr1:161188746..161188758, +
2.17e-129FFCP PHASE2:Hg19::chr20:1517991..1518011,-#_e3c25d87f2c558739a6a5d3f2efa0522p@chr20:1517991..1518011, -
2.17e-129FFCP PHASE1:Hg19::chr20:1517991..1518011,-#_e3c25d87f2c558739a6a5d3f2efa0522p@chr20:1517991..1518011, -
3.46e-129FFCP PHASE1:Hg19::chr18:2847062..2847071,+#_b438bf2c1b2b4b03dcab5f297d8cf515p7@EMILIN2
3.46e-129FFCP PHASE2:Hg19::chr18:2847062..2847071,+#_b438bf2c1b2b4b03dcab5f297d8cf515p7@EMILIN2
1.47e-128FFCP PHASE1:Hg19::chr19:18288514..18288554,+#_60b688a8880e20917480e69e4203049bp6@IFI30
1.47e-128FFCP PHASE2:Hg19::chr19:18288514..18288554,+#_60b688a8880e20917480e69e4203049bp6@IFI30
1.78e-128FFCP PHASE1:Hg19::chr19:18288914..18288931,-#_d5ef1b1ee934e4194ca8716b48979a9fp5@CU676849, p5@CU689079
1.78e-128FFCP PHASE2:Hg19::chr19:18288914..18288931,-#_d5ef1b1ee934e4194ca8716b48979a9fp5@CU676849, p5@CU689079
2.01e-128FFCP PHASE1:Hg19::chr5:180242576..180242585,-#_730634d1674e108b07f6a2eb6edfc442p12@MGAT1
2.01e-128FFCP PHASE2:Hg19::chr5:180242576..180242585,-#_730634d1674e108b07f6a2eb6edfc442p12@MGAT1
2.32e-127FFCP PHASE2:Hg19::chr17:40168698..40168726,-#_abfeb65177e726fd323583a223585b2cp1@AK126179
2.32e-127FFCP PHASE1:Hg19::chr17:40168698..40168726,-#_abfeb65177e726fd323583a223585b2cp1@AK126179
2.49e-127FFCP PHASE2:Hg19::chr17:7483714..7483726,+#_e0d88c96369c96b1e5d91962e639251fp@chr17:7483714..7483726, +
2.49e-127FFCP PHASE1:Hg19::chr17:7483714..7483726,+#_e0d88c96369c96b1e5d91962e639251fp@chr17:7483714..7483726, +
1.19e-126FFCP PHASE2:Hg19::chr22:46998103..46998127,-#_84e611626b660d30260e46e90b0663f8p@chr22:46998103..46998127, -
1.19e-126FFCP PHASE1:Hg19::chr22:46998103..46998127,-#_84e611626b660d30260e46e90b0663f8p@chr22:46998103..46998127, -
2.16e-126FFCP PHASE1:Hg19::chr19:18285955..18285972,+#_fba4086eacf5afd1da98627bce89761fp@chr19:18285955..18285972, +
2.16e-126FFCP PHASE2:Hg19::chr19:18285955..18285972,+#_fba4086eacf5afd1da98627bce89761fp@chr19:18285955..18285972, +
3.83e-126FFCP PHASE1:Hg19::chr19:51625924..51625942,+#_86f653e2de32b7f766441eccf1de0b97p@chr19:51625924..51625942, +
3.83e-126FFCP PHASE2:Hg19::chr19:51625924..51625942,+#_86f653e2de32b7f766441eccf1de0b97p@chr19:51625924..51625942, +
7.27e-126FFCP PHASE1:Hg19::chr4:185266972..185267007,+#_316b79ce5423accaad38c75d10fde2e7p@chr4:185266972..185267007, +
7.27e-126FFCP PHASE2:Hg19::chr4:185266972..185267007,+#_316b79ce5423accaad38c75d10fde2e7p@chr4:185266972..185267007, +
2.66e-125FFCP PHASE2:Hg19::chrX:152086449..152086473,+#_eca2e4b93dc4d2c6442809775a8a4a1ep4@ZNF185
2.66e-125FFCP PHASE1:Hg19::chrX:152086449..152086473,+#_eca2e4b93dc4d2c6442809775a8a4a1ep4@ZNF185
7.73e-125FFCP PHASE1:Hg19::chr2:145276939..145276960,+#_be349a1e8de9f6b6bb88b623691564afp2@ZEB2-AS1
7.73e-125FFCP PHASE2:Hg19::chr2:145276939..145276960,+#_be349a1e8de9f6b6bb88b623691564afp2@ZEB2-AS1
8.12e-125FFCP PHASE2:Hg19::chr15:59469817..59469836,+#_fcd4c25a59dc3dfdb0b62f44d4b2be7fp@chr15:59469817..59469836, +
8.12e-125FFCP PHASE1:Hg19::chr15:59469817..59469836,+#_fcd4c25a59dc3dfdb0b62f44d4b2be7fp@chr15:59469817..59469836, +
1.56e-124FFCP PHASE2:Hg19::chr20:1517945..1517963,-#_8765b9a28df16066fc15597555102345p@chr20:1517945..1517963, -
1.56e-124FFCP PHASE1:Hg19::chr20:1517945..1517963,-#_8765b9a28df16066fc15597555102345p@chr20:1517945..1517963, -
1.65e-124FFCP PHASE2:Hg19::chr8:116588888..116588904,+#_8fb7935f71e7fff85d15f3c240e92a0cp@chr8:116588888..116588904, +
1.65e-124FFCP PHASE1:Hg19::chr8:116588888..116588904,+#_8fb7935f71e7fff85d15f3c240e92a0cp@chr8:116588888..116588904, +
1.87e-124FFCP PHASE1:Hg19::chr1:161188686..161188721,+#_db871f724dd1cb535b1e2fd5e1c5a8f9p@chr1:161188686..161188721, +
1.87e-124FFCP PHASE2:Hg19::chr1:161188686..161188721,+#_db871f724dd1cb535b1e2fd5e1c5a8f9p@chr1:161188686..161188721, +
7.08e-124FFCP PHASE1:Hg19::chr5:77845080..77845099,-#_1e146dfffc22e0314bc63ce44a75a785p10@LHFPL2
7.08e-124FFCP PHASE2:Hg19::chr5:77845080..77845099,-#_1e146dfffc22e0314bc63ce44a75a785p10@LHFPL2
1.48e-123FFCP PHASE1:Hg19::chr9:137264970..137264982,+#_aa7511b85f2a1e3cad5c3a78d9f8bfecp@chr9:137264970..137264982, +
1.48e-123FFCP PHASE2:Hg19::chr9:137264970..137264982,+#_aa7511b85f2a1e3cad5c3a78d9f8bfecp@chr9:137264970..137264982, +
6.01e-123FFCP PHASE1:Hg19::chr17:47294661..47294681,+#_9026c774fa910cfd7e1ee56534abe5bcp@chr17:47294661..47294681, +
6.01e-123FFCP PHASE2:Hg19::chr17:47294661..47294681,+#_9026c774fa910cfd7e1ee56534abe5bcp@chr17:47294661..47294681, +
1.14e-122FFCP PHASE1:Hg19::chr1:108593061..108593077,+#_dfae09b8f2f4c1d38c0fe0a717999444p@chr1:108593061..108593077, +
1.14e-122FFCP PHASE2:Hg19::chr1:108593061..108593077,+#_dfae09b8f2f4c1d38c0fe0a717999444p@chr1:108593061..108593077, +
2.07e-122FFCP PHASE2:Hg19::chrX:153286067..153286101,-#_929e38fa12176c43a36d6661debcb4c4p@chrX:153286067..153286101, -
2.07e-122FFCP PHASE1:Hg19::chrX:153286067..153286101,-#_929e38fa12176c43a36d6661debcb4c4p@chrX:153286067..153286101, -
3.07e-122FFCP PHASE2:Hg19::chr14:103587759..103587770,+#_cc6bdb2fd862874483ad1315c85b8a4dp@chr14:103587759..103587770, +
3.07e-122FFCP PHASE1:Hg19::chr14:103587759..103587770,+#_cc6bdb2fd862874483ad1315c85b8a4dp@chr14:103587759..103587770, +
7.82e-122FFCP PHASE1:Hg19::chr1:17945095..17945126,+#_fc43791f170e5292958c3443d3afaa3bp7@ARHGEF10L
7.82e-122FFCP PHASE2:Hg19::chr1:17945095..17945126,+#_fc43791f170e5292958c3443d3afaa3bp7@ARHGEF10L
3.27e-121FFCP PHASE2:Hg19::chr16:50313426..50313459,+#_07ec231a4b78a6b79863b8737a6ecb9ap@chr16:50313426..50313459, +
3.27e-121FFCP PHASE1:Hg19::chr16:50313426..50313459,+#_07ec231a4b78a6b79863b8737a6ecb9ap@chr16:50313426..50313459, +
3.74e-121FFCP PHASE2:Hg19::chr10:20105868..20105875,+#_33e63c6c9a3afe9a1a7fb4976e44b15cp8@PLXDC2
3.74e-121FFCP PHASE1:Hg19::chr10:20105868..20105875,+#_33e63c6c9a3afe9a1a7fb4976e44b15cp8@PLXDC2
7.36e-121FFCP PHASE2:Hg19::chr1:150705526..150705571,-#_9ea519f00fc69383f66ba0e36a069dd6p@chr1:150705526..150705571, -
7.36e-121FFCP PHASE1:Hg19::chr1:150705526..150705571,-#_9ea519f00fc69383f66ba0e36a069dd6p@chr1:150705526..150705571, -
1.75e-120FFCP PHASE2:Hg19::chr19:18283959..18283993,+#_b1cab155c87608b88a6c19df27e98097p@chr19:18283959..18283993, +
1.75e-120FFCP PHASE1:Hg19::chr19:18283959..18283993,+#_b1cab155c87608b88a6c19df27e98097p@chr19:18283959..18283993, +

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