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{{CL
{{CL
|id=CL:0000502
|alt_id=
|name=type D enteroendocrine cell
|namespace=cell
|def="A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:A.03.492.766.440.175]
|xref=FMA:62935
|is_a=CL:0000164;;CL:0000172
|synonym="D cell" EXACT []
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:A.03.492.766.440.175]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0000502
|is_a=CL:0000164 ;;CL:0000172
|is_obsolete=
|located_in=
|located_in=
|name=type D enteroendocrine cell
|namespace=cell
|obo_creation_date=
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="D cell" EXACT []
|union_of=
|xref=FMA:62935
}}
}}

Revision as of 10:18, 12 September 2014

Name:type D enteroendocrine cell
Namespace:cell
Definition:"A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:A.03.492.766.440.175]
Xrefs:
links:
FMA:62935
Synonyms: "D cell" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000164(enteroendocrine cell),CL:0000172(somatostatin secreting cell)



Children


is a:CL:0000173 (pancreatic D cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

Mouse (Mus musculus)


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000502 (type D enteroendocrine cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
5.42e-195FFCP PHASE1:Hg19::chr18:56815879..56815901,+#_3a9a11466ed203209add935a85df3b37p@chr18:56815879..56815901, +
5.42e-195FFCP PHASE2:Hg19::chr18:56815879..56815901,+#_3a9a11466ed203209add935a85df3b37p@chr18:56815879..56815901, +
5.42e-195FFCP PHASE1:Hg19::chr1:193232079..193232084,+#_3a9a11466ed203209add935a85df3b37p@chr1:193232079..193232084, +
5.42e-195FFCP PHASE2:Hg19::chr6:50692244..50692251,+#_3a9a11466ed203209add935a85df3b37p@chr6:50692244..50692251, +
5.42e-195FFCP PHASE2:Hg19::chr1:193232144..193232147,+#_3a9a11466ed203209add935a85df3b37p@chr1:193232144..193232147, +
5.42e-195FFCP PHASE2:Hg19::chr10:120200137..120200154,+#_3a9a11466ed203209add935a85df3b37p@chr10:120200137..120200154, +
5.42e-195FFCP PHASE2:Hg19::chr1:193186161..193186169,-#_3a9a11466ed203209add935a85df3b37p@chr1:193186161..193186169, -
5.42e-195FFCP PHASE1:Hg19::chr10:120200137..120200154,+#_3a9a11466ed203209add935a85df3b37p@chr10:120200137..120200154, +
5.42e-195FFCP PHASE2:Hg19::chr9:96678236..96678246,-#_3a9a11466ed203209add935a85df3b37p@chr9:96678236..96678246, -
5.42e-195FFCP PHASE2:Hg19::chr20:20173664..20173680,+#_3a9a11466ed203209add935a85df3b37p@chr20:20173664..20173680, +
5.42e-195FFCP PHASE2:Hg19::chr9:77257468..77257474,-#_3a9a11466ed203209add935a85df3b37p@chr9:77257468..77257474, -
5.42e-195FFCP PHASE1:Hg19::chr6:50692244..50692251,+#_3a9a11466ed203209add935a85df3b37p@chr6:50692244..50692251, +
5.42e-195FFCP PHASE1:Hg19::chr1:193232144..193232147,+#_3a9a11466ed203209add935a85df3b37p@chr1:193232144..193232147, +
5.42e-195FFCP PHASE1:Hg19::chr20:20173664..20173680,+#_3a9a11466ed203209add935a85df3b37p@chr20:20173664..20173680, +
5.42e-195FFCP PHASE1:Hg19::chr9:96678236..96678246,-#_3a9a11466ed203209add935a85df3b37p@chr9:96678236..96678246, -
5.42e-195FFCP PHASE1:Hg19::chr1:193186161..193186169,-#_3a9a11466ed203209add935a85df3b37p@chr1:193186161..193186169, -
5.42e-195FFCP PHASE2:Hg19::chr1:193232079..193232084,+#_3a9a11466ed203209add935a85df3b37p@chr1:193232079..193232084, +
5.42e-195FFCP PHASE1:Hg19::chr9:77257468..77257474,-#_3a9a11466ed203209add935a85df3b37p@chr9:77257468..77257474, -
5.42e-195FFCP PHASE2:Hg19::chr12:70464665..70464668,+#_3a9a11466ed203209add935a85df3b37p@chr12:70464665..70464668, +
5.42e-195FFCP PHASE1:Hg19::chr12:70464665..70464668,+#_3a9a11466ed203209add935a85df3b37p@chr12:70464665..70464668, +
9.37e-99FFCP PHASE2:Hg19::chr1:193232096..193232117,+#_9195cecf6fa326765be33afa6a4f8306p@chr1:193232096..193232117, +
9.37e-99FFCP PHASE2:Hg19::chr12:70464675..70464680,+#_9195cecf6fa326765be33afa6a4f8306p@chr12:70464675..70464680, +
9.37e-99FFCP PHASE1:Hg19::chr12:70464675..70464680,+#_9195cecf6fa326765be33afa6a4f8306p@chr12:70464675..70464680, +
9.37e-99FFCP PHASE1:Hg19::chr4:139208173..139208199,-#_9195cecf6fa326765be33afa6a4f8306p@chr4:139208173..139208199, -
9.37e-99FFCP PHASE1:Hg19::chr18:7955271..7955280,+#_9195cecf6fa326765be33afa6a4f8306p@chr18:7955271..7955280, +
9.37e-99FFCP PHASE2:Hg19::chr18:7955271..7955280,+#_9195cecf6fa326765be33afa6a4f8306p@chr18:7955271..7955280, +
9.37e-99FFCP PHASE2:Hg19::chr6:154858221..154858224,-#_9195cecf6fa326765be33afa6a4f8306p@chr6:154858221..154858224, -
9.37e-99FFCP PHASE2:Hg19::chr4:173014804..173014812,+#_9195cecf6fa326765be33afa6a4f8306p@chr4:173014804..173014812, +
9.37e-99FFCP PHASE2:Hg19::chr9:77257424..77257435,-#_9195cecf6fa326765be33afa6a4f8306p@chr9:77257424..77257435, -
9.37e-99FFCP PHASE2:Hg19::chr6:161970049..161970057,-#_9195cecf6fa326765be33afa6a4f8306p3@GU361471
9.37e-99FFCP PHASE1:Hg19::chr1:193232096..193232117,+#_9195cecf6fa326765be33afa6a4f8306p@chr1:193232096..193232117, +
9.37e-99FFCP PHASE2:Hg19::chr12:70464593..70464598,+#_9195cecf6fa326765be33afa6a4f8306p@chr12:70464593..70464598, +
9.37e-99FFCP PHASE1:Hg19::chr12:70464593..70464598,+#_9195cecf6fa326765be33afa6a4f8306p@chr12:70464593..70464598, +
9.37e-99FFCP PHASE1:Hg19::chr6:154858221..154858224,-#_9195cecf6fa326765be33afa6a4f8306p@chr6:154858221..154858224, -
9.37e-99FFCP PHASE1:Hg19::chr4:173014804..173014812,+#_9195cecf6fa326765be33afa6a4f8306p@chr4:173014804..173014812, +
9.37e-99FFCP PHASE2:Hg19::chr6:154858237..154858245,-#_9195cecf6fa326765be33afa6a4f8306p@chr6:154858237..154858245, -
9.37e-99FFCP PHASE2:Hg19::chr1:193186195..193186210,-#_9195cecf6fa326765be33afa6a4f8306p@chr1:193186195..193186210, -
9.37e-99FFCP PHASE1:Hg19::chr9:77257424..77257435,-#_9195cecf6fa326765be33afa6a4f8306p@chr9:77257424..77257435, -
9.37e-99FFCP PHASE1:Hg19::chr6:161970049..161970057,-#_9195cecf6fa326765be33afa6a4f8306p3@GU361471
9.37e-99FFCP PHASE2:Hg19::chr4:59982412..59982425,+#_9195cecf6fa326765be33afa6a4f8306p@chr4:59982412..59982425, +
9.37e-99FFCP PHASE1:Hg19::chr6:154858237..154858245,-#_9195cecf6fa326765be33afa6a4f8306p@chr6:154858237..154858245, -
9.37e-99FFCP PHASE1:Hg19::chr4:59982412..59982425,+#_9195cecf6fa326765be33afa6a4f8306p@chr4:59982412..59982425, +
9.37e-99FFCP PHASE2:Hg19::chr18:56813724..56813731,+#_9195cecf6fa326765be33afa6a4f8306p@chr18:56813724..56813731, +
9.37e-99FFCP PHASE1:Hg19::chr1:193186195..193186210,-#_9195cecf6fa326765be33afa6a4f8306p@chr1:193186195..193186210, -
9.37e-99FFCP PHASE1:Hg19::chr18:56813724..56813731,+#_9195cecf6fa326765be33afa6a4f8306p@chr18:56813724..56813731, +
9.37e-99FFCP PHASE2:Hg19::chr4:139208173..139208199,-#_9195cecf6fa326765be33afa6a4f8306p@chr4:139208173..139208199, -
2.55e-98FFCP PHASE2:Hg19::chr1:110661599..110661609,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr1:110661599..110661609, -
2.55e-98FFCP PHASE1:Hg19::chr6:132980338..132980346,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr6:132980338..132980346, -
2.55e-98FFCP PHASE1:Hg19::chr1:110661599..110661609,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr1:110661599..110661609, -
2.55e-98FFCP PHASE1:Hg19::chr18:56816249..56816258,+#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr18:56816249..56816258, +
2.55e-98FFCP PHASE2:Hg19::chr18:56816249..56816258,+#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr18:56816249..56816258, +
2.55e-98FFCP PHASE2:Hg19::chr6:154858334..154858342,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr6:154858334..154858342, -
2.55e-98FFCP PHASE2:Hg19::chr13:93508642..93508652,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr13:93508642..93508652, -
2.55e-98FFCP PHASE1:Hg19::chr13:93508642..93508652,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr13:93508642..93508652, -
2.55e-98FFCP PHASE2:Hg19::chr6:132980338..132980346,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr6:132980338..132980346, -
2.55e-98FFCP PHASE1:Hg19::chr6:154858334..154858342,-#_09bd09f45cb69e70a2a3a41e9c2ba07fp@chr6:154858334..154858342, -
1.23e-66FFCP PHASE2:Hg19::chr9:77257683..77257703,+#_5a242fd9b38f470e3f5649832a88df58p@chr9:77257683..77257703, +
1.23e-66FFCP PHASE1:Hg19::chr19:7570269..7570273,+#_5a242fd9b38f470e3f5649832a88df58p13@C19orf45
1.23e-66FFCP PHASE2:Hg19::chr1:110678110..110678115,+#_5a242fd9b38f470e3f5649832a88df58p@chr1:110678110..110678115, +
1.23e-66FFCP PHASE1:Hg19::chr9:77257683..77257703,+#_5a242fd9b38f470e3f5649832a88df58p@chr9:77257683..77257703, +
1.23e-66FFCP PHASE1:Hg19::chr18:56815158..56815162,+#_5a242fd9b38f470e3f5649832a88df58p@chr18:56815158..56815162, +
1.23e-66FFCP PHASE2:Hg19::chr18:56815158..56815162,+#_5a242fd9b38f470e3f5649832a88df58p@chr18:56815158..56815162, +
1.23e-66FFCP PHASE2:Hg19::chr12:128108552..128108561,+#_5a242fd9b38f470e3f5649832a88df58p1@ENST00000537470
1.23e-66FFCP PHASE1:Hg19::chr12:128108552..128108561,+#_5a242fd9b38f470e3f5649832a88df58p1@ENST00000537470
1.23e-66FFCP PHASE1:Hg19::chr1:110678110..110678115,+#_5a242fd9b38f470e3f5649832a88df58p@chr1:110678110..110678115, +
1.23e-66FFCP PHASE1:Hg19::chr12:127385138..127385144,-#_5a242fd9b38f470e3f5649832a88df58p@chr12:127385138..127385144, -
1.23e-66FFCP PHASE2:Hg19::chr12:127385138..127385144,-#_5a242fd9b38f470e3f5649832a88df58p@chr12:127385138..127385144, -
1.23e-66FFCP PHASE1:Hg19::chr18:7955176..7955183,+#_5a242fd9b38f470e3f5649832a88df58p@chr18:7955176..7955183, +
1.23e-66FFCP PHASE2:Hg19::chr18:7955176..7955183,+#_5a242fd9b38f470e3f5649832a88df58p@chr18:7955176..7955183, +
1.23e-66FFCP PHASE2:Hg19::chr12:70464652..70464662,+#_5a242fd9b38f470e3f5649832a88df58p@chr12:70464652..70464662, +
1.23e-66FFCP PHASE1:Hg19::chr12:70464652..70464662,+#_5a242fd9b38f470e3f5649832a88df58p@chr12:70464652..70464662, +
1.23e-66FFCP PHASE2:Hg19::chr1:110678228..110678236,+#_5a242fd9b38f470e3f5649832a88df58p@chr1:110678228..110678236, +
1.23e-66FFCP PHASE1:Hg19::chr1:110678228..110678236,+#_5a242fd9b38f470e3f5649832a88df58p@chr1:110678228..110678236, +
1.23e-66FFCP PHASE2:Hg19::chr19:7570269..7570273,+#_5a242fd9b38f470e3f5649832a88df58p13@C19orf45
2.39e-66FFCP PHASE2:Hg19::chr13:93587956..93587973,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr13:93587956..93587973, +
2.39e-66FFCP PHASE1:Hg19::chr13:93587956..93587973,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr13:93587956..93587973, +
2.39e-66FFCP PHASE2:Hg19::chr15:92459318..92459327,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr15:92459318..92459327, +
2.39e-66FFCP PHASE2:Hg19::chr12:128077388..128077416,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr12:128077388..128077416, +
2.39e-66FFCP PHASE1:Hg19::chr12:128077388..128077416,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr12:128077388..128077416, +
2.39e-66FFCP PHASE1:Hg19::chr1:165198157..165198181,-#_81b8ad2250cb0e568ad28ab0caf86de4p@chr1:165198157..165198181, -
2.39e-66FFCP PHASE1:Hg19::chr15:92459318..92459327,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr15:92459318..92459327, +
2.39e-66FFCP PHASE1:Hg19::chr7:120381641..120381650,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr7:120381641..120381650, +
2.39e-66FFCP PHASE1:Hg19::chr18:56816267..56816276,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr18:56816267..56816276, +
2.39e-66FFCP PHASE2:Hg19::chr18:56816267..56816276,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr18:56816267..56816276, +
2.39e-66FFCP PHASE2:Hg19::chr2:159855059..159855068,-#_81b8ad2250cb0e568ad28ab0caf86de4p@chr2:159855059..159855068, -
2.39e-66FFCP PHASE2:Hg19::chr4:3310694..3310716,-#_81b8ad2250cb0e568ad28ab0caf86de4p@chr4:3310694..3310716, -
2.39e-66FFCP PHASE2:Hg19::chr5:77683792..77683799,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr5:77683792..77683799, +
2.39e-66FFCP PHASE2:Hg19::chr5:104246731..104246738,-#_81b8ad2250cb0e568ad28ab0caf86de4p3@ENST00000524336
2.39e-66FFCP PHASE1:Hg19::chr2:159855059..159855068,-#_81b8ad2250cb0e568ad28ab0caf86de4p@chr2:159855059..159855068, -
2.39e-66FFCP PHASE2:Hg19::chr1:165198157..165198181,-#_81b8ad2250cb0e568ad28ab0caf86de4p@chr1:165198157..165198181, -
2.39e-66FFCP PHASE1:Hg19::chr4:3310694..3310716,-#_81b8ad2250cb0e568ad28ab0caf86de4p@chr4:3310694..3310716, -
2.39e-66FFCP PHASE1:Hg19::chr5:77683792..77683799,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr5:77683792..77683799, +
2.39e-66FFCP PHASE2:Hg19::chr7:120381641..120381650,+#_81b8ad2250cb0e568ad28ab0caf86de4p@chr7:120381641..120381650, +
2.39e-66FFCP PHASE1:Hg19::chr5:104246731..104246738,-#_81b8ad2250cb0e568ad28ab0caf86de4p3@ENST00000524336
4.66e-66FFCP PHASE2:Hg19::chr19:51412411..51412426,-#_5f4b31e4c8ae92b9701615383b096001p4@KLK4
4.66e-66FFCP PHASE2:Hg19::chr7:100807523..100807543,+#_5f4b31e4c8ae92b9701615383b096001p@chr7:100807523..100807543, +
4.66e-66FFCP PHASE2:Hg19::chr20:11077086..11077098,+#_5f4b31e4c8ae92b9701615383b096001p@chr20:11077086..11077098, +
4.66e-66FFCP PHASE1:Hg19::chr19:51412411..51412426,-#_5f4b31e4c8ae92b9701615383b096001p4@KLK4
4.66e-66FFCP PHASE1:Hg19::chr20:11077086..11077098,+#_5f4b31e4c8ae92b9701615383b096001p@chr20:11077086..11077098, +
4.66e-66FFCP PHASE2:Hg19::chr14:101165430..101165451,-#_5f4b31e4c8ae92b9701615383b096001p@chr14:101165430..101165451, -