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{{CL
{{CL
|id=CL:0002679
|alt_id=
|name=natural helper lymphocyte
|namespace=cell
|def="A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13" [GOC:tfm, PMID:20023630]
|xref=
|is_a=CL:0000542
|synonym=
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=tmeehan
|created_by=tmeehan
|obo_creation_date=2011-08-29T10:08:02Z
|def="A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13" [GOC:tfm, PMID:20023630]
|subset=
|derives_from=
|derives_from=
|develops_from=
|develops_from=
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0002679
|is_a=CL:0000542
|is_obsolete=
|located_in=
|located_in=
|name=natural helper lymphocyte
|namespace=cell
|obo_creation_date=2011-08-29T10:08:02Z
|part_of=
|part_of=
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym=
|union_of=
|xref=
}}
}}

Revision as of 10:30, 12 September 2014

Name:natural helper lymphocyte
Namespace:cell
Definition:"A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13" [GOC:tfm, PMID:20023630]
Created by:tmeehan
Creation date:2011-08-29T10:08:02Z


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0000542(lymphocyte)



Children


derives from:FF:0011137 (mouse natural helper cells- IL2 treated sample),FF:0011138 (mouse natural helper cells- IL33 treated- 01hr sample),FF:0011139 (mouse natural helper cells- IL33 treated- day02 sample),FF:0011140 (mouse natural helper cells- naive sample),FF:0011524 (mouse natural helper cells- IL2 treated, day15 sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002679 (natural helper lymphocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.62e-30FFCP PHASE2:Mm9::chr3:86355678..86355705,+#_8a4d0abd3d764cb294c6441cd6cb520bp@chr3:86355678..86355705, +
5.62e-30FFCP PHASE1:Mm9::chr3:86355678..86355705,+#_8a4d0abd3d764cb294c6441cd6cb520bp@chr3:86355678..86355705, +
8.39e-23FFCP PHASE2:Mm9::chr11:57645265..57645268,-#_275b4ad1d61cc38b2955b1182fb359d1p@chr11:57645265..57645268, -
8.39e-23FFCP PHASE1:Mm9::chr11:57645265..57645268,-#_275b4ad1d61cc38b2955b1182fb359d1p@chr11:57645265..57645268, -
1.39e-22FFCP PHASE1:Mm9::chr10:62892183..62892185,-#_5350dcb29b95b139e61313c768b92652p@chr10:62892183..62892185, -
1.39e-22FFCP PHASE2:Mm9::chr10:62892183..62892185,-#_5350dcb29b95b139e61313c768b92652p@chr10:62892183..62892185, -
5.15e-19FFCP PHASE1:Mm9::chr13:114939956..114939970,-#_ff8034975385f427d49d05ffe9483cbap@chr13:114939956..114939970, -
5.15e-19FFCP PHASE2:Mm9::chr13:114939956..114939970,-#_ff8034975385f427d49d05ffe9483cbap@chr13:114939956..114939970, -
7.74e-19FFCP PHASE1:Mm9::chr6:99154949..99154968,-#_4818c279aca804804a28671f9481e72fp@chr6:99154949..99154968, -
7.74e-19FFCP PHASE2:Mm9::chr6:99154949..99154968,-#_4818c279aca804804a28671f9481e72fp@chr6:99154949..99154968, -
1.74e-18FFCP PHASE1:Mm9::chr10:104733601..104733605,-#_fc0f2a79799853c8fd17d25931c1a0bfp@chr10:104733601..104733605, -
1.74e-18FFCP PHASE1:Mm9::chr13:56710849..56710850,+#_fc0f2a79799853c8fd17d25931c1a0bfp7@Tgfbi
1.74e-18FFCP PHASE2:Mm9::chr13:56710849..56710850,+#_fc0f2a79799853c8fd17d25931c1a0bfp7@Tgfbi
1.74e-18FFCP PHASE1:Mm9::chr10:119799722..119799725,-#_fc0f2a79799853c8fd17d25931c1a0bfp@chr10:119799722..119799725, -
1.74e-18FFCP PHASE2:Mm9::chr10:104733601..104733605,-#_fc0f2a79799853c8fd17d25931c1a0bfp@chr10:104733601..104733605, -
1.74e-18FFCP PHASE2:Mm9::chr10:119799722..119799725,-#_fc0f2a79799853c8fd17d25931c1a0bfp@chr10:119799722..119799725, -
9.51e-16FFCP PHASE2:Mm9::chr7:111000331..111000338,-#_88c8fe37f54517a6f7a648ff86f8174bp@chr7:111000331..111000338, -
9.51e-16FFCP PHASE1:Mm9::chr7:111000331..111000338,-#_88c8fe37f54517a6f7a648ff86f8174bp@chr7:111000331..111000338, -
1.33e-15FFCP PHASE2:Mm9::chr13:63674450..63674454,-#_5f45186f10496e7da219c05510d463b2p11@Ptch1
1.33e-15FFCP PHASE1:Mm9::chr13:63674450..63674454,-#_5f45186f10496e7da219c05510d463b2p11@Ptch1
1.86e-15FFCP PHASE1:Mm9::chr15:11650313..11650319,-#_ee0844f6d409c23998fb9bebd1377043p@chr15:11650313..11650319, -
1.86e-15FFCP PHASE2:Mm9::chr11:57642737..57642748,-#_ee0844f6d409c23998fb9bebd1377043p@chr11:57642737..57642748, -
1.86e-15FFCP PHASE2:Mm9::chr15:11650313..11650319,-#_ee0844f6d409c23998fb9bebd1377043p@chr15:11650313..11650319, -
1.86e-15FFCP PHASE1:Mm9::chr11:57642737..57642748,-#_ee0844f6d409c23998fb9bebd1377043p@chr11:57642737..57642748, -
1.55e-13FFCP PHASE1:Mm9::chr15:51621796..51621814,-#_501d7198696e7d3130965deb2c8f2ee0p@chr15:51621796..51621814, -
1.55e-13FFCP PHASE2:Mm9::chr15:51621796..51621814,-#_501d7198696e7d3130965deb2c8f2ee0p@chr15:51621796..51621814, -
3.34e-12FFCP PHASE2:Mm9::chr15:102849395..102849404,+#_37a9d9b4105c88ac4b1b2409953791dap4@Hoxc4
3.34e-12FFCP PHASE1:Mm9::chr15:102849395..102849404,+#_37a9d9b4105c88ac4b1b2409953791dap4@Hoxc4
4.3e-12FFCP PHASE2:Mm9::chr19:24750790..24750799,-#_dc799e0e0eefffd6d6c5cecc0d8174bbp@chr19:24750790..24750799, -
4.3e-12FFCP PHASE1:Mm9::chr19:24750790..24750799,-#_dc799e0e0eefffd6d6c5cecc0d8174bbp@chr19:24750790..24750799, -
5.53e-12FFCP PHASE2:Mm9::chr6:4706731..4706742,+#_dda1334c90a5df40100812f91bc33e19p8@Peg10
5.53e-12FFCP PHASE1:Mm9::chr17:45707413..45707418,+#_dda1334c90a5df40100812f91bc33e19p@chr17:45707413..45707418, +
5.53e-12FFCP PHASE1:Mm9::chr6:4706731..4706742,+#_dda1334c90a5df40100812f91bc33e19p8@Peg10
5.53e-12FFCP PHASE2:Mm9::chr11:32177763..32177774,-#_dda1334c90a5df40100812f91bc33e19p@chr11:32177763..32177774, -
5.53e-12FFCP PHASE2:Mm9::chr17:45707413..45707418,+#_dda1334c90a5df40100812f91bc33e19p@chr17:45707413..45707418, +
5.53e-12FFCP PHASE1:Mm9::chr11:32177763..32177774,-#_dda1334c90a5df40100812f91bc33e19p@chr11:32177763..32177774, -
7.11e-12FFCP PHASE1:Mm9::chr6:4704193..4704201,+#_f3287f6e7ac5991274de9df81cc547bdp@chr6:4704193..4704201, +
7.11e-12FFCP PHASE2:Mm9::chr14:117749554..117749561,+#_f3287f6e7ac5991274de9df81cc547bdp@chr14:117749554..117749561, +
7.11e-12FFCP PHASE1:Mm9::chr14:117749554..117749561,+#_f3287f6e7ac5991274de9df81cc547bdp@chr14:117749554..117749561, +
7.11e-12FFCP PHASE2:Mm9::chr6:4704193..4704201,+#_f3287f6e7ac5991274de9df81cc547bdp@chr6:4704193..4704201, +
1.83e-11FFCP PHASE1:Mm9::chr9:119350671..119350677,+#_9d52bfdc582ca6062fa3248d26689aedp@chr9:119350671..119350677, +
1.83e-11FFCP PHASE2:Mm9::chr9:119350671..119350677,+#_9d52bfdc582ca6062fa3248d26689aedp@chr9:119350671..119350677, +
2.9e-11FFCP PHASE1:Mm9::chr11:11781140..11781150,-#_0fc0cd4e47fe90a4d6ce211f2b83d238p@chr11:11781140..11781150, -
2.9e-11FFCP PHASE2:Mm9::chr11:11781140..11781150,-#_0fc0cd4e47fe90a4d6ce211f2b83d238p@chr11:11781140..11781150, -
3.65e-11FFCP PHASE2:Mm9::chr5:76130865..76130881,+#_bbcdd9240372691e7364e520a84f3a2ep@chr5:76130865..76130881, +
3.65e-11FFCP PHASE1:Mm9::chr5:76130865..76130881,+#_bbcdd9240372691e7364e520a84f3a2ep@chr5:76130865..76130881, +
5.74e-11FFCP PHASE2:Mm9::chr19:38171348..38171379,+#_d96663cda6bb9cc657d8518d33c0623ep2@O3far1
5.74e-11FFCP PHASE1:Mm9::chr19:38171348..38171379,+#_d96663cda6bb9cc657d8518d33c0623ep2@O3far1
7.19e-11FFCP PHASE1:Mm9::chr15:51621825..51621843,-#_1fb978583068421f5bbcae446bd8a8abp@chr15:51621825..51621843, -
7.19e-11FFCP PHASE2:Mm9::chr15:51621825..51621843,-#_1fb978583068421f5bbcae446bd8a8abp@chr15:51621825..51621843, -
1.12e-10FFCP PHASE2:Mm9::chr7:149846239..149846248,+#_eecf385c2268f574e59538c993302df2p@chr7:149846239..149846248, +
1.12e-10FFCP PHASE2:Mm9::chr6:4706860..4706872,+#_eecf385c2268f574e59538c993302df2p10@Peg10
1.12e-10FFCP PHASE1:Mm9::chr1:94336361..94336369,-#_eecf385c2268f574e59538c993302df2p@chr1:94336361..94336369, -
1.12e-10FFCP PHASE1:Mm9::chr7:149846239..149846248,+#_eecf385c2268f574e59538c993302df2p@chr7:149846239..149846248, +
1.12e-10FFCP PHASE2:Mm9::chr1:94336361..94336369,-#_eecf385c2268f574e59538c993302df2p@chr1:94336361..94336369, -
1.12e-10FFCP PHASE1:Mm9::chr6:4706860..4706872,+#_eecf385c2268f574e59538c993302df2p10@Peg10
8.42e-10FFCP PHASE2:Mm9::chr2:115874845..115874865,-#_6e5ce1d0dad4a726d4f30c815bc23cb4p20@Meis2
8.42e-10FFCP PHASE2:Mm9::chr13:48758072..48758117,-#_6e5ce1d0dad4a726d4f30c815bc23cb4p@chr13:48758072..48758117, -
8.42e-10FFCP PHASE1:Mm9::chr13:48758072..48758117,-#_6e5ce1d0dad4a726d4f30c815bc23cb4p@chr13:48758072..48758117, -
8.42e-10FFCP PHASE1:Mm9::chr2:115874845..115874865,-#_6e5ce1d0dad4a726d4f30c815bc23cb4p20@Meis2
8.42e-10FFCP PHASE2:Mm9::chr19:10303261..10303283,-#_6e5ce1d0dad4a726d4f30c815bc23cb4p@chr19:10303261..10303283, -
8.42e-10FFCP PHASE2:Mm9::chr13:48758431..48758443,+#_6e5ce1d0dad4a726d4f30c815bc23cb4p3@Barx1
8.42e-10FFCP PHASE1:Mm9::chr13:48758431..48758443,+#_6e5ce1d0dad4a726d4f30c815bc23cb4p3@Barx1
8.42e-10FFCP PHASE1:Mm9::chr19:10303261..10303283,-#_6e5ce1d0dad4a726d4f30c815bc23cb4p@chr19:10303261..10303283, -
1.03e-9FFCP PHASE1:Mm9::chr5:67486110..67486118,-#_cdd19db268d5c9f4049bc6d1cc42bcccp@chr5:67486110..67486118, -
1.03e-9FFCP PHASE2:Mm9::chr5:67486110..67486118,-#_cdd19db268d5c9f4049bc6d1cc42bcccp@chr5:67486110..67486118, -
1.19e-9FFCP PHASE1:Mm9::chr1:178766069..178766082,-#_0dcf6ad40bd42d59d53a61a386c8925cp2@Hmga2-ps1
1.19e-9FFCP PHASE2:Mm9::chr1:178766069..178766082,-#_0dcf6ad40bd42d59d53a61a386c8925cp2@Hmga2-ps1
1.44e-9FFCP PHASE2:Mm9::chr19:38863592..38863600,-#_df75868cd5e4392ce251e9ddd05e9149p@chr19:38863592..38863600, -
1.44e-9FFCP PHASE1:Mm9::chr19:38863592..38863600,-#_df75868cd5e4392ce251e9ddd05e9149p@chr19:38863592..38863600, -
3.04e-9FFCP PHASE2:Mm9::chr11:57642948..57642962,-#_2861a83ba762f9161301b3fd663db527p@chr11:57642948..57642962, -
3.04e-9FFCP PHASE1:Mm9::chr11:57642948..57642962,-#_2861a83ba762f9161301b3fd663db527p@chr11:57642948..57642962, -
3.65e-9FFCP PHASE1:Mm9::chr11:57645644..57645649,-#_898ff1ebb1f5273ba2162bd791bd19b7p3@Hand1
3.65e-9FFCP PHASE1:Mm9::chr13:29043435..29043446,+#_898ff1ebb1f5273ba2162bd791bd19b7p@chr13:29043435..29043446, +
3.65e-9FFCP PHASE2:Mm9::chr13:29043435..29043446,+#_898ff1ebb1f5273ba2162bd791bd19b7p@chr13:29043435..29043446, +
3.65e-9FFCP PHASE2:Mm9::chr11:57645644..57645649,-#_898ff1ebb1f5273ba2162bd791bd19b7p3@Hand1
4.39e-9FFCP PHASE2:Mm9::chr7:111000379..111000390,-#_409998448cc4d589a53fa2b97ee4de89p@chr7:111000379..111000390, -
4.39e-9FFCP PHASE1:Mm9::chr7:111000379..111000390,-#_409998448cc4d589a53fa2b97ee4de89p@chr7:111000379..111000390, -
5.27e-9FFCP PHASE2:Mm9::chr2:16346144..16346149,+#_5c10da6ca1ccf82080750f9a5a107e7ep@chr2:16346144..16346149, +
5.27e-9FFCP PHASE2:Mm9::chr14:33691561..33691572,+#_5c10da6ca1ccf82080750f9a5a107e7ep@chr14:33691561..33691572, +
5.27e-9FFCP PHASE1:Mm9::chr2:16346144..16346149,+#_5c10da6ca1ccf82080750f9a5a107e7ep@chr2:16346144..16346149, +
5.27e-9FFCP PHASE1:Mm9::chr14:33691561..33691572,+#_5c10da6ca1ccf82080750f9a5a107e7ep@chr14:33691561..33691572, +
5.27e-9FFCP PHASE2:Mm9::chr16:77329743..77329754,+#_5c10da6ca1ccf82080750f9a5a107e7ep14@2810055G20Rik
5.27e-9FFCP PHASE1:Mm9::chr16:77329743..77329754,+#_5c10da6ca1ccf82080750f9a5a107e7ep14@2810055G20Rik
6.33e-9FFCP PHASE2:Mm9::chr6:34696382..34696393,-#_b89b919c46ca211165f46c9089a0066dp@chr6:34696382..34696393, -
6.33e-9FFCP PHASE1:Mm9::chr2:74583741..74583750,+#_b89b919c46ca211165f46c9089a0066dp10@Hoxd3
6.33e-9FFCP PHASE1:Mm9::chr6:34696382..34696393,-#_b89b919c46ca211165f46c9089a0066dp@chr6:34696382..34696393, -
6.33e-9FFCP PHASE2:Mm9::chr2:74583741..74583750,+#_b89b919c46ca211165f46c9089a0066dp10@Hoxd3
7.41e-9FFCP PHASE1:Mm9::chr13:31717671..31717682,+#_302e8df95fd4a55ef344fa485efa5fdep5@Foxf2
7.41e-9FFCP PHASE2:Mm9::chr13:31717671..31717682,+#_302e8df95fd4a55ef344fa485efa5fdep5@Foxf2
8.81e-9FFCP PHASE2:Mm9::chr1:180697124..180697130,+#_26c5559c580c3e9625951b3e879827abp@chr1:180697124..180697130, +
8.81e-9FFCP PHASE1:Mm9::chr1:180697124..180697130,+#_26c5559c580c3e9625951b3e879827abp@chr1:180697124..180697130, +
1.05e-8FFCP PHASE2:Mm9::chr6:52167632..52167645,+#_55653d191df3d636c94aeb2497327e5ap@chr6:52167632..52167645, +
1.05e-8FFCP PHASE1:Mm9::chr6:52167632..52167645,+#_55653d191df3d636c94aeb2497327e5ap@chr6:52167632..52167645, +
1.05e-8FFCP PHASE2:Mm9::chr16:73046021..73046033,+#_55653d191df3d636c94aeb2497327e5ap@chr16:73046021..73046033, +
1.05e-8FFCP PHASE1:Mm9::chr16:73046021..73046033,+#_55653d191df3d636c94aeb2497327e5ap@chr16:73046021..73046033, +
1.24e-8FFCP PHASE2:Mm9::chr17:75562268..75562272,+#_ee66dc756cc9d0345ee92e3f2d1029f3p@chr17:75562268..75562272, +
1.24e-8FFCP PHASE1:Mm9::chr17:75562268..75562272,+#_ee66dc756cc9d0345ee92e3f2d1029f3p@chr17:75562268..75562272, +
1.47e-8FFCP PHASE2:Mm9::chr17:74737941..74737954,-#_e760de38b4331d3953262d014762685ap@chr17:74737941..74737954, -
1.47e-8FFCP PHASE2:Mm9::chr13:64376258..64376267,-#_e760de38b4331d3953262d014762685ap5@Cdc14b

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