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{{UBERON
{{UBERON
|id=UBERON:0000087
|alt_id=
|name=inner cell mass
|namespace=
|def="Mass of cells inside the primordial embryo that will eventually give rise to the definitive structures of the fetus. This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred. The ICM lies within the blastocoele (more correctly termed 'blastocyst cavity', as it is not strictly homologous to the blastocoele of anamniote vertebrates) and is entirely surrounded by the single layer of cells called trophoblast." [Wikipedia:Inner_cell_mass]
|xref=EFO:0000547;;EHDAA2:0000830;;EHDAA:40;;EMAPA:16041;;FMA:86557;;http://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/7/72/Blastocyst_English.svg/200px-Blastocyst_English.svg.png;;ncithesaurus:Inner_Cell_Mass;;SCTID:361456007;;VHOG:0000742
|is_a=UBERON:0002050
|synonym="embryoblast" RELATED [];;"embryoblastus; massa cellularis interna; pluriblastus senior" RELATED LATIN [Wikipedia:Inner_cell_mass];;"pluriblast" RELATED []
|comment=
|comment=
|alt_id=
|disjoint_from=
|union_of=
|created_by=
|created_by=
|obo_creation_date=
|def="Mass of cells inside the primordial embryo that will eventually give rise to the definitive structures of the fetus. This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred. The ICM lies within the blastocoele (more correctly termed 'blastocyst cavity', as it is not strictly homologous to the blastocoele of anamniote vertebrates) and is entirely surrounded by the single layer of cells called trophoblast." [Wikipedia:Inner_cell_mass]
|subset=early_development
|derives_from=
|derives_from=
|develops_from=UBERON:0000358
|develops_from=UBERON:0000085;;UBERON:0000358
|disjoint_from=
|has_quality=
|has_quality=
|id=UBERON:0000087
|is_a=UBERON:0002050
|is_obsolete=
|located_in=
|located_in=
|part_of=
|name=inner cell mass
|namespace=
|obo_creation_date=
|part_of=UBERON:0000922
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl
|is_obsolete=
|subset=early_development
|preceded_by=
|synonym="embryoblast" RELATED [];;"embryoblastus; massa cellularis interna; pluriblastus senior" RELATED LATIN [Wikipedia:Inner_cell_mass];;"pluriblast" RELATED []
|union_of=
|xref=EFO:0000547;;EHDAA2:0000830;;EHDAA:40;;EMAPA:16041;;FMA:86557;;http://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg;;http://upload.wikimedia.org/wikipedia/commons/thumb/7/72/Blastocyst_English.svg/200px-Blastocyst_English.svg.png;;ncithesaurus:Inner_Cell_Mass;;SCTID:361456007;;VHOG:0000742
}}
}}

Revision as of 10:51, 12 September 2014

Name:inner cell mass
Definition:"Mass of cells inside the primordial embryo that will eventually give rise to the definitive structures of the fetus. This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred. The ICM lies within the blastocoele (more correctly termed 'blastocyst cavity', as it is not strictly homologous to the blastocoele of anamniote vertebrates) and is entirely surrounded by the single layer of cells called trophoblast." [Wikipedia:Inner_cell_mass]
Xrefs:
links:

EFO:0000547
EHDAA2:0000830
EHDAA:40
EMAPA:16041
FMA:86557
[1]
[ 200px-Blastocyst_English.svg.png 200px-Blastocyst_English.svg.png]
ncithesaurus:Inner_Cell_Mass
SCTID:361456007

VHOG:0000742
Synonyms: "embryoblast" RELATED []
"embryoblastus; massa cellularis interna; pluriblastus senior" RELATED LATIN [Wikipedia:Inner_cell_mass]
"pluriblast" RELATED []
Subset: early_development

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0002050(embryonic structure)
develops_from:UBERON:0000085(morula),UBERON:0000358(blastocyst)
part_of:UBERON:0000922(embryo)



Children

develops from:UBERON:0000091 (bilaminar disc),UBERON:0008780 (inner cell mass derived epiblast)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology



Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000087 (inner cell mass), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
5.79e-79FFCP PHASE1:Hg19::chr7:135931480..135931486,+#_1dca9825b89a60e2fa381a048ee4971fp@chr7:135931480..135931486, +
5.79e-79FFCP PHASE1:Hg19::chr10:120921270..120921282,-#_1dca9825b89a60e2fa381a048ee4971fp@chr10:120921270..120921282, -
5.79e-79FFCP PHASE2:Hg19::chr10:120921270..120921282,-#_1dca9825b89a60e2fa381a048ee4971fp@chr10:120921270..120921282, -
5.79e-79FFCP PHASE2:Hg19::chr7:135931480..135931486,+#_1dca9825b89a60e2fa381a048ee4971fp@chr7:135931480..135931486, +
2.16e-63FFCP PHASE1:Hg19::chr1:205744117..205744127,-#_e5a4f94565027041fa0b09de30c72b79p8@RAB7L1
2.16e-63FFCP PHASE2:Hg19::chr1:205744117..205744127,-#_e5a4f94565027041fa0b09de30c72b79p8@RAB7L1
1.1e-59FFCP PHASE1:Hg19::chr22:20105576..20105585,+#_d2d0999b38e3591402cb47ae812aa340p11@RANBP1
1.1e-59FFCP PHASE1:Hg19::chr3:45926401..45926410,-#_d2d0999b38e3591402cb47ae812aa340p@chr3:45926401..45926410, -
1.1e-59FFCP PHASE2:Hg19::chr4:167951900..167951907,-#_d2d0999b38e3591402cb47ae812aa340p@chr4:167951900..167951907, -
1.1e-59FFCP PHASE2:Hg19::chr3:189266272..189266296,-#_d2d0999b38e3591402cb47ae812aa340p@chr3:189266272..189266296, -
1.1e-59FFCP PHASE1:Hg19::chr11:128154946..128154955,+#_d2d0999b38e3591402cb47ae812aa340p@chr11:128154946..128154955, +
1.1e-59FFCP PHASE1:Hg19::chr2:45063061..45063082,-#_d2d0999b38e3591402cb47ae812aa340p@chr2:45063061..45063082, -
1.1e-59FFCP PHASE2:Hg19::chr6:149464325..149464336,-#_d2d0999b38e3591402cb47ae812aa340p@chr6:149464325..149464336, -
1.1e-59FFCP PHASE2:Hg19::chr2:228216610..228216617,+#_d2d0999b38e3591402cb47ae812aa340p18@MFF
1.1e-59FFCP PHASE2:Hg19::chr1:146746588..146746604,+#_d2d0999b38e3591402cb47ae812aa340p5@CHD1L
1.1e-59FFCP PHASE1:Hg19::chr3:157301317..157301362,-#_d2d0999b38e3591402cb47ae812aa340p@chr3:157301317..157301362, -
1.1e-59FFCP PHASE2:Hg19::chr4:36393818..36393829,-#_d2d0999b38e3591402cb47ae812aa340p2@ENST00000504344
1.1e-59FFCP PHASE2:Hg19::chr19:42682291..42682301,-#_d2d0999b38e3591402cb47ae812aa340p@chr19:42682291..42682301, -
1.1e-59FFCP PHASE2:Hg19::chr7:106397647..106397655,+#_d2d0999b38e3591402cb47ae812aa340p@chr7:106397647..106397655, +
1.1e-59FFCP PHASE1:Hg19::chr6:491208..491217,-#_d2d0999b38e3591402cb47ae812aa340p@chr6:491208..491217, -
1.1e-59FFCP PHASE2:Hg19::chr14:76957775..76957781,+#_d2d0999b38e3591402cb47ae812aa340p@chr14:76957775..76957781, +
1.1e-59FFCP PHASE1:Hg19::chr1:212870782..212870788,-#_d2d0999b38e3591402cb47ae812aa340p@chr1:212870782..212870788, -
1.1e-59FFCP PHASE2:Hg19::chr8:38216859..38216889,-#_d2d0999b38e3591402cb47ae812aa340p@chr8:38216859..38216889, -
1.1e-59FFCP PHASE1:Hg19::chr7:106363986..106363994,-#_d2d0999b38e3591402cb47ae812aa340p@chr7:106363986..106363994, -
1.1e-59FFCP PHASE2:Hg19::chr20:22771722..22771733,+#_d2d0999b38e3591402cb47ae812aa340p@chr20:22771722..22771733, +
1.1e-59FFCP PHASE1:Hg19::chr2:15633244..15633249,+#_d2d0999b38e3591402cb47ae812aa340p@chr2:15633244..15633249, +
1.1e-59FFCP PHASE1:Hg19::chr7:142250880..142250889,-#_d2d0999b38e3591402cb47ae812aa340p4@AF430683, p4@AF430684, p4@AF430685
1.1e-59FFCP PHASE1:Hg19::chr4:167938808..167938815,-#_d2d0999b38e3591402cb47ae812aa340p@chr4:167938808..167938815, -
1.1e-59FFCP PHASE2:Hg19::chr2:148282641..148282654,+#_d2d0999b38e3591402cb47ae812aa340p@chr2:148282641..148282654, +
1.1e-59FFCP PHASE2:Hg19::chr3:180050773..180050786,+#_d2d0999b38e3591402cb47ae812aa340p@chr3:180050773..180050786, +
1.1e-59FFCP PHASE2:Hg19::chr21:18170731..18170736,-#_d2d0999b38e3591402cb47ae812aa340p@chr21:18170731..18170736, -
1.1e-59FFCP PHASE2:Hg19::chr11:128154946..128154955,+#_d2d0999b38e3591402cb47ae812aa340p@chr11:128154946..128154955, +
1.1e-59FFCP PHASE1:Hg19::chr2:228216642..228216661,+#_d2d0999b38e3591402cb47ae812aa340p11@MFF
1.1e-59FFCP PHASE1:Hg19::chr22:37484406..37484413,+#_d2d0999b38e3591402cb47ae812aa340p@chr22:37484406..37484413, +
1.1e-59FFCP PHASE2:Hg19::chr9:74986248..74986275,-#_d2d0999b38e3591402cb47ae812aa340p@chr9:74986248..74986275, -
1.1e-59FFCP PHASE1:Hg19::chr12:77198556..77198565,+#_d2d0999b38e3591402cb47ae812aa340p@chr12:77198556..77198565, +
1.1e-59FFCP PHASE1:Hg19::chr10:120921395..120921406,-#_d2d0999b38e3591402cb47ae812aa340p@chr10:120921395..120921406, -
1.1e-59FFCP PHASE1:Hg19::chr20:38442102..38442111,+#_d2d0999b38e3591402cb47ae812aa340p@chr20:38442102..38442111, +
1.1e-59FFCP PHASE1:Hg19::chr14:76957775..76957781,+#_d2d0999b38e3591402cb47ae812aa340p@chr14:76957775..76957781, +
1.1e-59FFCP PHASE1:Hg19::chr7:135735084..135735112,+#_d2d0999b38e3591402cb47ae812aa340p@chr7:135735084..135735112, +
1.1e-59FFCP PHASE1:Hg19::chr21:18180126..18180130,-#_d2d0999b38e3591402cb47ae812aa340p@chr21:18180126..18180130, -
1.1e-59FFCP PHASE1:Hg19::chr17:40021018..40021028,+#_d2d0999b38e3591402cb47ae812aa340p@chr17:40021018..40021028, +
1.1e-59FFCP PHASE2:Hg19::chr2:53245239..53245255,-#_d2d0999b38e3591402cb47ae812aa340p@chr2:53245239..53245255, -
1.1e-59FFCP PHASE1:Hg19::chr9:74997054..74997058,-#_d2d0999b38e3591402cb47ae812aa340p@chr9:74997054..74997058, -
1.1e-59FFCP PHASE1:Hg19::chr7:17543537..17543548,-#_d2d0999b38e3591402cb47ae812aa340p@chr7:17543537..17543548, -
1.1e-59FFCP PHASE2:Hg19::chr4:167983163..167983209,-#_d2d0999b38e3591402cb47ae812aa340p@chr4:167983163..167983209, -
1.1e-59FFCP PHASE1:Hg19::chr19:49488921..49488932,-#_d2d0999b38e3591402cb47ae812aa340p@chr19:49488921..49488932, -
1.1e-59FFCP PHASE1:Hg19::chr10:31996512..31996530,-#_d2d0999b38e3591402cb47ae812aa340p5@ENST00000433770
1.1e-59FFCP PHASE1:Hg19::chr3:111319059..111319101,-#_d2d0999b38e3591402cb47ae812aa340p@chr3:111319059..111319101, -
1.1e-59FFCP PHASE1:Hg19::chr1:207617923..207617929,-#_d2d0999b38e3591402cb47ae812aa340p@chr1:207617923..207617929, -
1.1e-59FFCP PHASE2:Hg19::chr17:1985278..1985290,-#_d2d0999b38e3591402cb47ae812aa340p@chr17:1985278..1985290, -
1.1e-59FFCP PHASE2:Hg19::chr10:120921395..120921406,-#_d2d0999b38e3591402cb47ae812aa340p@chr10:120921395..120921406, -
1.1e-59FFCP PHASE1:Hg19::chr6:87324164..87324175,+#_d2d0999b38e3591402cb47ae812aa340p@chr6:87324164..87324175, +
1.1e-59FFCP PHASE1:Hg19::chr6:149490934..149490939,-#_d2d0999b38e3591402cb47ae812aa340p@chr6:149490934..149490939, -
1.1e-59FFCP PHASE2:Hg19::chr6:42362820..42362827,-#_d2d0999b38e3591402cb47ae812aa340p@chr6:42362820..42362827, -
1.1e-59FFCP PHASE2:Hg19::chr4:167932279..167932291,-#_d2d0999b38e3591402cb47ae812aa340p@chr4:167932279..167932291, -
1.1e-59FFCP PHASE1:Hg19::chr2:2930946..2930963,+#_d2d0999b38e3591402cb47ae812aa340p@chr2:2930946..2930963, +
1.1e-59FFCP PHASE2:Hg19::chr3:119281371..119281382,-#_d2d0999b38e3591402cb47ae812aa340p@chr3:119281371..119281382, -
1.1e-59FFCP PHASE1:Hg19::chr12:129054695..129054717,-#_d2d0999b38e3591402cb47ae812aa340p@chr12:129054695..129054717, -
1.1e-59FFCP PHASE2:Hg19::chr19:40074306..40074328,+#_d2d0999b38e3591402cb47ae812aa340p@chr19:40074306..40074328, +
1.1e-59FFCP PHASE1:Hg19::chr3:119279036..119279047,+#_d2d0999b38e3591402cb47ae812aa340p@chr3:119279036..119279047, +
1.1e-59FFCP PHASE2:Hg19::chr21:18180062..18180079,-#_d2d0999b38e3591402cb47ae812aa340p@chr21:18180062..18180079, -
1.1e-59FFCP PHASE1:Hg19::chr5:28145264..28145272,-#_d2d0999b38e3591402cb47ae812aa340p@chr5:28145264..28145272, -
1.1e-59FFCP PHASE2:Hg19::chr9:74996801..74996811,-#_d2d0999b38e3591402cb47ae812aa340p@chr9:74996801..74996811, -
1.1e-59FFCP PHASE2:Hg19::chr10:31996512..31996530,-#_d2d0999b38e3591402cb47ae812aa340p5@ENST00000433770
1.1e-59FFCP PHASE1:Hg19::chr7:106363860..106363870,-#_d2d0999b38e3591402cb47ae812aa340p@chr7:106363860..106363870, -
1.1e-59FFCP PHASE2:Hg19::chr3:45926401..45926410,-#_d2d0999b38e3591402cb47ae812aa340p@chr3:45926401..45926410, -
1.1e-59FFCP PHASE2:Hg19::chr22:37484379..37484392,+#_d2d0999b38e3591402cb47ae812aa340p@chr22:37484379..37484392, +
1.1e-59FFCP PHASE1:Hg19::chr2:148293141..148293150,+#_d2d0999b38e3591402cb47ae812aa340p@chr2:148293141..148293150, +
1.1e-59FFCP PHASE2:Hg19::chr7:102945487..102945492,+#_d2d0999b38e3591402cb47ae812aa340p@chr7:102945487..102945492, +
1.1e-59FFCP PHASE2:Hg19::chr3:75655787..75655802,-#_d2d0999b38e3591402cb47ae812aa340p@chr3:75655787..75655802, -
1.1e-59FFCP PHASE2:Hg19::chr14:76017386..76017395,-#_d2d0999b38e3591402cb47ae812aa340p@chr14:76017386..76017395, -
1.1e-59FFCP PHASE2:Hg19::chr12:129054695..129054717,-#_d2d0999b38e3591402cb47ae812aa340p@chr12:129054695..129054717, -
1.1e-59FFCP PHASE1:Hg19::chr2:228216535..228216554,+#_d2d0999b38e3591402cb47ae812aa340p14@MFF
1.1e-59FFCP PHASE2:Hg19::chr6:138023078..138023089,-#_d2d0999b38e3591402cb47ae812aa340p@chr6:138023078..138023089, -
1.1e-59FFCP PHASE1:Hg19::chrX:109653507..109653518,+#_d2d0999b38e3591402cb47ae812aa340p@chrX:109653507..109653518, +
1.1e-59FFCP PHASE2:Hg19::chr3:195306434..195306439,-#_d2d0999b38e3591402cb47ae812aa340p10@APOD
1.1e-59FFCP PHASE1:Hg19::chr19:53511711..53511720,-#_d2d0999b38e3591402cb47ae812aa340p@chr19:53511711..53511720, -
1.1e-59FFCP PHASE1:Hg19::chr14:76017386..76017395,-#_d2d0999b38e3591402cb47ae812aa340p@chr14:76017386..76017395, -
1.1e-59FFCP PHASE1:Hg19::chr7:135705366..135705371,+#_d2d0999b38e3591402cb47ae812aa340p@chr7:135705366..135705371, +
1.1e-59FFCP PHASE1:Hg19::chr21:18179708..18179733,-#_d2d0999b38e3591402cb47ae812aa340p@chr21:18179708..18179733, -
1.1e-59FFCP PHASE2:Hg19::chr2:11264766..11264775,-#_d2d0999b38e3591402cb47ae812aa340p@chr2:11264766..11264775, -
1.1e-59FFCP PHASE2:Hg19::chr19:49488905..49488920,-#_d2d0999b38e3591402cb47ae812aa340p@chr19:49488905..49488920, -
1.1e-59FFCP PHASE1:Hg19::chr9:74995216..74995247,-#_d2d0999b38e3591402cb47ae812aa340p@chr9:74995216..74995247, -
1.1e-59FFCP PHASE1:Hg19::chrX:10129292..10129306,+#_d2d0999b38e3591402cb47ae812aa340p@chrX:10129292..10129306, +
1.1e-59FFCP PHASE1:Hg19::chr6:150322254..150322291,-#_d2d0999b38e3591402cb47ae812aa340p@chr6:150322254..150322291, -
1.1e-59FFCP PHASE2:Hg19::chr4:167957459..167957470,-#_d2d0999b38e3591402cb47ae812aa340p@chr4:167957459..167957470, -
1.1e-59FFCP PHASE2:Hg19::chr21:43934923..43934932,+#_d2d0999b38e3591402cb47ae812aa340p@chr21:43934923..43934932, +
1.1e-59FFCP PHASE1:Hg19::chr5:77713534..77713543,+#_d2d0999b38e3591402cb47ae812aa340p@chr5:77713534..77713543, +
1.1e-59FFCP PHASE2:Hg19::chr9:94933452..94933457,+#_d2d0999b38e3591402cb47ae812aa340p@chr9:94933452..94933457, +
1.1e-59FFCP PHASE2:Hg19::chr2:228216642..228216661,+#_d2d0999b38e3591402cb47ae812aa340p11@MFF
1.1e-59FFCP PHASE2:Hg19::chr20:38442102..38442111,+#_d2d0999b38e3591402cb47ae812aa340p@chr20:38442102..38442111, +
1.1e-59FFCP PHASE2:Hg19::chr14:76957782..76957792,+#_d2d0999b38e3591402cb47ae812aa340p@chr14:76957782..76957792, +
1.1e-59FFCP PHASE2:Hg19::chr4:167791926..167791930,-#_d2d0999b38e3591402cb47ae812aa340p@chr4:167791926..167791930, -
1.1e-59FFCP PHASE1:Hg19::chr8:59970765..59970787,-#_d2d0999b38e3591402cb47ae812aa340p@chr8:59970765..59970787, -
1.1e-59FFCP PHASE1:Hg19::chr7:106397597..106397610,+#_d2d0999b38e3591402cb47ae812aa340p@chr7:106397597..106397610, +
1.1e-59FFCP PHASE1:Hg19::chr6:31150998..31151005,-#_d2d0999b38e3591402cb47ae812aa340p@chr6:31150998..31151005, -
1.1e-59FFCP PHASE1:Hg19::chr3:153038353..153038371,+#_d2d0999b38e3591402cb47ae812aa340p@chr3:153038353..153038371, +
1.1e-59FFCP PHASE1:Hg19::chr6:135486487..135486491,+#_d2d0999b38e3591402cb47ae812aa340p@chr6:135486487..135486491, +
1.1e-59FFCP PHASE1:Hg19::chr5:146717844..146717861,+#_d2d0999b38e3591402cb47ae812aa340p@chr5:146717844..146717861, +

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