MCL coexpression mm9:234
From FANTOM5_SSTAR
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005179 | hormone activity | 0.000777753843365325 |
GO:0005184 | neuropeptide hormone activity | 0.00112128625682927 |
GO:0007189 | G-protein signaling, adenylate cyclase activating pathway | 0.00259495703963575 |
GO:0007188 | G-protein signaling, coupled to cAMP nucleotide second messenger | 0.00363546449479802 |
GO:0007187 | G-protein signaling, coupled to cyclic nucleotide second messenger | 0.00363546449479802 |
GO:0019933 | cAMP-mediated signaling | 0.00363546449479802 |
GO:0019935 | cyclic-nucleotide-mediated signaling | 0.00363546449479802 |
GO:0007218 | neuropeptide signaling pathway | 0.00533245676509797 |
GO:0031770 | growth hormone-releasing hormone receptor binding | 0.00533245676509797 |
GO:0005102 | receptor binding | 0.00646076510102083 |
GO:0022410 | circadian sleep/wake cycle process | 0.00646076510102083 |
GO:0045187 | regulation of circadian sleep/wake cycle, sleep | 0.00646076510102083 |
GO:0042749 | regulation of circadian sleep/wake cycle | 0.00646076510102083 |
GO:0050802 | circadian sleep/wake cycle, sleep | 0.00646076510102083 |
GO:0019932 | second-messenger-mediated signaling | 0.00646076510102083 |
GO:0042752 | regulation of circadian rhythm | 0.00799649412726543 |
GO:0060124 | positive regulation of growth hormone secretion | 0.00799649412726543 |
GO:0042745 | circadian sleep/wake cycle | 0.00799649412726543 |
GO:0007186 | G-protein coupled receptor protein signaling pathway | 0.00946449151263321 |
GO:0060123 | regulation of growth hormone secretion | 0.00959447862860534 |
GO:0048512 | circadian behavior | 0.0104273527136281 |
GO:0046887 | positive regulation of hormone secretion | 0.0104273527136281 |
GO:0030431 | sleep | 0.0104273527136281 |
GO:0043195 | terminal button | 0.0110675198728754 |
GO:0030252 | growth hormone secretion | 0.0110675198728754 |
GO:0021984 | adenohypophysis development | 0.0110675198728754 |
GO:0007622 | rhythmic behavior | 0.0124321773442802 |
GO:0046457 | prostanoid biosynthetic process | 0.0127856310031625 |
GO:0009755 | hormone-mediated signaling | 0.0127856310031625 |
GO:0001516 | prostaglandin biosynthetic process | 0.0127856310031625 |
GO:0007242 | intracellular signaling cascade | 0.0130483789778046 |
GO:0033267 | axon part | 0.0134829982803515 |
GO:0051047 | positive regulation of secretion | 0.0145251465394777 |
GO:0007166 | cell surface receptor linked signal transduction | 0.0155718198200468 |
GO:0007190 | adenylate cyclase activation | 0.0155718198200468 |
GO:0045762 | positive regulation of adenylate cyclase activity | 0.0155718198200468 |
GO:0031281 | positive regulation of cyclase activity | 0.0155718198200468 |
GO:0006693 | prostaglandin metabolic process | 0.0155718198200468 |
GO:0051349 | positive regulation of lyase activity | 0.0155718198200468 |
GO:0006692 | prostanoid metabolic process | 0.0155718198200468 |
GO:0045761 | regulation of adenylate cyclase activity | 0.0182451842133976 |
GO:0009725 | response to hormone stimulus | 0.0182451842133976 |
GO:0031279 | regulation of cyclase activity | 0.0191521964900769 |
GO:0021983 | pituitary gland development | 0.0191521964900769 |
GO:0051339 | regulation of lyase activity | 0.0191521964900769 |
GO:0046883 | regulation of hormone secretion | 0.020369096904043 |
GO:0021536 | diencephalon development | 0.020369096904043 |
GO:0040018 | positive regulation of multicellular organism growth | 0.0219332061928605 |
GO:0046456 | icosanoid biosynthetic process | 0.0234324059863803 |
GO:0045927 | positive regulation of growth | 0.024870591313716 |
GO:0030072 | peptide hormone secretion | 0.0261593210842317 |
GO:0002790 | peptide secretion | 0.0261593210842317 |
GO:0007623 | circadian rhythm | 0.0261593210842317 |
GO:0006690 | icosanoid metabolic process | 0.0265565931679067 |
GO:0015833 | peptide transport | 0.0329905833999019 |
GO:0046879 | hormone secretion | 0.0349451179678578 |
GO:0007165 | signal transduction | 0.0378623178446707 |
GO:0035270 | endocrine system development | 0.0394627785810368 |
GO:0051046 | regulation of secretion | 0.0413036714176191 |
GO:0040014 | regulation of multicellular organism growth | 0.0413036714176191 |
GO:0001664 | G-protein-coupled receptor binding | 0.0429527559484707 |
GO:0007154 | cell communication | 0.0434650748053211 |
GO:0005615 | extracellular space | 0.0452583109456235 |
GO:0035264 | multicellular organism growth | 0.0453681727674484 |
GO:0030424 | axon | 0.0453962838751811 |
GO:0044463 | cell projection part | 0.0489666142369662 |
GO:0006633 | fatty acid biosynthetic process | 0.0489666142369662 |
GO:0044421 | extracellular region part | 0.0491541024175729 |
GO:0046394 | carboxylic acid biosynthetic process | 0.0495224249914147 |
GO:0016053 | organic acid biosynthetic process | 0.0495224249914147 |
GO:0048732 | gland development | 0.0495224249914147 |
Relative expression of the co-expression cluster over median <br>Analyst:
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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
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