MCL coexpression mm9:990

Phase1 CAGE Peaks

	Short description
Mm9::chr2:25089697..25089712,-	p3@Slc34a3
Mm9::chr2:25089723..25089743,-	p1@Slc34a3
Mm9::chr2:25089747..25089771,-	p2@Slc34a3
Mm9::chr4:133074652..133074665,+	p7@1810019J16Rik
Mm9::chr4:49486777..49486790,-	p1@Acnat1
Mm9::chr5:114453822..114453840,+	p2@Dao
Mm9::chr5:64646376..64646396,-	p@chr5:64646376..64646396 -
Mm9::chr7:135070423..135070434,-	p@chr7:135070423..135070434 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0006551	leucine metabolic process	0.00690259664969827
GO:0003884	D-amino-acid oxidase activity	0.00690259664969827
GO:0015321	sodium-dependent phosphate transmembrane transporter activity	0.00690259664969827
GO:0009081	branched chain family amino acid metabolic process	0.0110426418245154
GO:0015114	phosphate transmembrane transporter activity	0.0110426418245154
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	0.0181103811418533
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	0.0181103811418533
GO:0005903	brush border	0.0181103811418533
GO:0015103	inorganic anion transmembrane transporter activity	0.0214600372087656
GO:0016324	apical plasma membrane	0.0337801000208444
GO:0006817	phosphate transport	0.0404009348764478
GO:0045177	apical part of cell	0.0404009348764478
GO:0031402	sodium ion binding	0.0404009348764478
GO:0042579	microbody	0.0404009348764478
GO:0005777	peroxisome	0.0404009348764478
GO:0008509	anion transmembrane transporter activity	0.0453401334749049
GO:0006814	sodium ion transport	0.0453401334749049

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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