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MCL coexpression mm9:1510

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:36226756..36226803,+p2@Hs3st5
Mm9::chr11:33743676..33743687,-p7@Kcnip1
Mm9::chr11:33743693..33743713,-p4@Kcnip1
Mm9::chr6:114081373..114081432,+p@chr6:114081373..114081432
+
Mm9::chr7:4072035..4072068,-p1@ENSMUST00000050989
p1@ENSMUST00000132560
p1@ENSMUST00000149343


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005332gamma-aminobutyric acid:sodium symporter activity0.0172527099321138
GO:0015185L-gamma-aminobutyric acid transmembrane transporter activity0.0172527099321138
GO:0008467heparin-glucosamine 3-O-sulfotransferase activity0.0172527099321138
GO:0005283sodium:amino acid symporter activity0.0172527099321138
GO:0005416cation:amino acid symporter activity0.0206998488307872
GO:0008324cation transmembrane transporter activity0.0214356684575052
GO:0005328neurotransmitter:sodium symporter activity0.023645078476576
GO:0005343organic acid:sodium symporter activity0.023645078476576
GO:0005326neurotransmitter transporter activity0.023645078476576
GO:0015075ion transmembrane transporter activity0.023645078476576
GO:0015179L-amino acid transmembrane transporter activity0.024026836959118
GO:0022891substrate-specific transmembrane transporter activity0.0260457337476539
GO:0005275amine transmembrane transporter activity0.0278406913503091
GO:0015171amino acid transmembrane transporter activity0.0278406913503091
GO:0022857transmembrane transporter activity0.0278406913503091
GO:0015370solute:sodium symporter activity0.0280570260138593
GO:0022892substrate-specific transporter activity0.0280570260138593
GO:0008146sulfotransferase activity0.0280570260138593
GO:0006836neurotransmitter transport0.0284089374572476
GO:0016782transferase activity, transferring sulfur-containing groups0.0284089374572476
GO:0015294solute:cation symporter activity0.0284089374572476
GO:0046943carboxylic acid transmembrane transporter activity0.0289219912115317
GO:0005342organic acid transmembrane transporter activity0.0289219912115317



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neurectoderm1.68e-3264
neural plate1.68e-3264
presumptive neural plate1.68e-3264
regional part of nervous system1.72e-3154
neural tube1.07e-2952
neural rod1.07e-2952
future spinal cord1.07e-2952
neural keel1.07e-2952
central nervous system1.48e-2973
nervous system3.55e-2875
ectoderm-derived structure6.77e-2895
ectoderm6.77e-2895
presumptive ectoderm6.77e-2895
ecto-epithelium1.06e-2773
pre-chordal neural plate1.60e-2649
brain1.07e-2447
future brain1.07e-2447
structure with developmental contribution from neural crest8.54e-2492
regional part of brain1.11e-2346
gray matter2.14e-2234
anterior neural tube1.91e-2140
regional part of forebrain1.85e-2039
forebrain1.85e-2039
future forebrain1.85e-2039
brain grey matter1.79e-1729
regional part of telencephalon1.79e-1729
telencephalon1.79e-1729
cerebral cortex1.36e-1121
cerebral hemisphere1.36e-1121
pallium1.36e-1121
regional part of cerebral cortex9.23e-1017
occipital lobe8.74e-0910
visual cortex8.74e-0910
neocortex8.74e-0910
posterior neural tube1.23e-0812
chordal neural plate1.23e-0812
basal ganglion3.07e-078
nuclear complex of neuraxis3.07e-078
aggregate regional part of brain3.07e-078
collection of basal ganglia3.07e-078
cerebral subcortex3.07e-078
spinal cord3.18e-076
dorsal region element3.18e-076
dorsum3.18e-076


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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