MCL coexpression mm9:1413

Phase1 CAGE Peaks

	Short description
Mm9::chr18:64499674..64499696,+	p1@Onecut2
Mm9::chr18:64499706..64499721,+	p2@Onecut2
Mm9::chr19:10678806..10678827,-	p1@Dak
Mm9::chr19:10708713..10708735,+	p1@Vwce
Mm9::chr1:187278792..187278810,+	p2@Slc30a10
Mm9::chr4:40649821..40649836,-	p5@Aptx

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004371	glycerone kinase activity	0.00693949852992203
GO:0035312	5'-3' exodeoxyribonuclease activity	0.00693949852992203
GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity	0.00693949852992203
GO:0006266	DNA ligation	0.0104083923340189
GO:0000012	single strand break repair	0.0130072829079902
GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.0130072829079902
GO:0004529	exodeoxyribonuclease activity	0.0130072829079902
GO:0008409	5'-3' exonuclease activity	0.0130072829079902
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.0346433490759716
GO:0004536	deoxyribonuclease activity	0.0346433490759716
GO:0006071	glycerol metabolic process	0.0346433490759716
GO:0019751	polyol metabolic process	0.0346433490759716
GO:0006829	zinc ion transport	0.0351705411114708

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
intestine	6.67e-15	31
gastrointestinal system	7.29e-14	47
liver	2.50e-13	22
epithelial sac	2.50e-13	22
digestive gland	2.50e-13	22
epithelium of foregut-midgut junction	2.50e-13	22
anatomical boundary	2.50e-13	22
hepatobiliary system	2.50e-13	22
foregut-midgut junction	2.50e-13	22
hepatic diverticulum	2.50e-13	22
liver primordium	2.50e-13	22
septum transversum	2.50e-13	22
liver bud	2.50e-13	22
digestive tract diverticulum	1.68e-12	23
sac	1.68e-12	23
exocrine gland	6.59e-10	25
exocrine system	6.59e-10	25
mucosa	7.65e-09	15
intestinal mucosa	6.84e-08	13
anatomical wall	6.84e-08	13
wall of intestine	6.84e-08	13
gastrointestinal system mucosa	6.84e-08	13
abdomen element	3.01e-07	49
abdominal segment element	3.01e-07	49
abdominal segment of trunk	3.01e-07	49
abdomen	3.01e-07	49

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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