MCL coexpression mm9:2526

Phase1 CAGE Peaks

	Short description
Mm9::chr10:127103729..127103802,-	p1@Nab2
Mm9::chr10:33926983..33927006,-	p2@Dse
Mm9::chr10:33927007..33927071,-	p1@Dse

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0047757	chondroitin-glucuronate 5-epimerase activity	0.00865611132416589
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	0.0138471222878844
GO:0014037	Schwann cell differentiation	0.0138471222878844
GO:0045682	regulation of epidermis development	0.0138471222878844
GO:0001958	endochondral ossification	0.0138471222878844
GO:0016854	racemase and epimerase activity	0.017307005837869
GO:0007422	peripheral nervous system development	0.0250834680669186
GO:0042552	myelination	0.0250834680669186
GO:0007272	ensheathment of neurons	0.0250834680669186
GO:0008366	axon ensheathment	0.0250834680669186
GO:0001508	regulation of action potential	0.0272701288295061
GO:0010001	glial cell differentiation	0.0272701288295061
GO:0042063	gliogenesis	0.0272701288295061
GO:0001503	ossification	0.0493937890147435
GO:0031214	biomineral formation	0.0493937890147435
GO:0008544	epidermis development	0.0493937890147435
GO:0007398	ectoderm development	0.0493937890147435
GO:0046849	bone remodeling	0.0493937890147435

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
thoracic cavity element	1.73e-07	17
thoracic segment organ	1.73e-07	17
thoracic cavity	1.73e-07	17
thoracic segment of trunk	1.73e-07	17
respiratory primordium	1.73e-07	17
endoderm of foregut	1.73e-07	17

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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