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UBERON:0000007

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Name:pituitary gland
Definition:"The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." [Wikipedia:Pituitary_gland, ZFIN:curator]
Xrefs:
links:

AAO:0010536
BM:Die-Hy-HY
BTO:0001073
EFO:0000857
EHDAA2:0001471
EHDAA:2183
EHDAA:4477
EMAPA:16647
EMAPA:16898
EV:0100132
FMA:13889
GAID:457
[ Gray1180.png Gray1180.png]
[ 200px-Gray1180.png 200px-Gray1180.png]
MA:0000176
MAT:0000077
MESH:A.06.407.747
MIAA:0000077
ncithesaurus:Pituitary_Gland
NIF_GrossAnatomy:birnlex_1353
OpenCyc:Mx4rv6NQYJwpEbGdrcN5Y29ycA
SCTID:181125003
TAO:0000118
VHOG:0000143
XAO:0000017

ZFA:0000118
Synonyms: "glandula pituitaria" RELATED [BTO:0001073]
"hypophysis" RELATED [ZFA:0000118]
"hypophysis cerebri" RELATED [MA:0000176]
"hypophysis, glandula pituitaria" RELATED LATIN [Wikipedia:Pituitary_gland]
"pituitary" EXACT [BTO:0001073]
"pituitary body" EXACT [BTO:0001073]
Comments:Taxon notes: The lamprey possesses a distinct pituitary organ and hormones, the ascidian does not show distinct evidence of them [Sower S, Freamat M, Kavanaugh S. The origins of the vertebrate hypothalamic遯ｶ闖殃tuitary遯ｶ蝣ｵonadal (HPG) and hypothalamic遯ｶ闖殃tuitary遯ｶ骰紘yroid (HPT) endocrine systems: new insights from lampreys. Gen Comp Endocrinol 2009;161:20-9]
Subset: organ_slim
uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0003296(gland of diencephalon),UBERON:0010133(neuroendocrine gland),UBERON:0010314(structure with developmental contribution from neural crest)
develops_from:UBERON:0000924(ectoderm)
part_of:UBERON:0001894(diencephalon)



Children

derives from:FF:0010162 (human pituitary gland - adult sample),FF:0011303 (mouse pituitary gland- adult sample),FF:0011317 (mouse pituitary gland- embryo E12 sample),FF:0011325 (mouse pituitary gland- embryo E13 sample),FF:0011334 (mouse pituitary gland- embryo E14 sample),FF:0011345 (mouse pituitary gland- embryo E15 sample),FF:0011353 (mouse pituitary gland- embryo E16 sample),FF:0011507 (mouse pituitary gland- neonate N00 sample),FF:0011519 (mouse pituitary gland- embryo E17 sample)
part of:FF:0000114 (mouse pituitary cell),UBERON:0002196 (adenohypophysis)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000007 (pituitary gland), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
3.29e-195FFCP PHASE2:Hg19::chr3:87325636..87325643,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@POU1F1
3.29e-195FFCP PHASE2:Hg19::chr17:61995979..61995990,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@AB591020
3.29e-195FFCP PHASE1:Hg19::chr17:61994760..61994767,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994760..61994767, +
3.29e-195FFCP PHASE2:Hg19::chr8:126582844..126582849,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:126582844..126582849, -
3.29e-195FFCP PHASE1:Hg19::chr3:130248948..130248959,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:130248948..130248959, +
3.29e-195FFCP PHASE2:Hg19::chr7:31006649..31006651,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr7:31006649..31006651, +
3.29e-195FFCP PHASE2:Hg19::chr17:61995207..61995219,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995207..61995219, -
3.29e-195FFCP PHASE2:Hg19::chr6:22287710..22287718,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287710..22287718, -
3.29e-195FFCP PHASE1:Hg19::chr19:7979665..7979675,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr19:7979665..7979675, +
3.29e-195FFCP PHASE2:Hg19::chr9:135964996..135965001,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr9:135964996..135965001, +
3.29e-195FFCP PHASE1:Hg19::chr6:22287815..22287820,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287815..22287820, -
3.29e-195FFCP PHASE1:Hg19::chr8:130017368..130017390,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:130017368..130017390, +
3.29e-195FFCP PHASE1:Hg19::chr19:2608406..2608413,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr19:2608406..2608413, -
3.29e-195FFCP PHASE1:Hg19::chr7:31006831..31006834,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr7:31006831..31006834, +
3.29e-195FFCP PHASE1:Hg19::chr6:22287647..22287662,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287647..22287662, -
3.29e-195FFCP PHASE1:Hg19::chr17:61996018..61996019,-#_47bedeeeae192cbe89ab07ee58e0dcb1p5@AB591020
3.29e-195FFCP PHASE1:Hg19::chr17:18021982..18021985,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@MYO15A
3.29e-195FFCP PHASE1:Hg19::chr17:61995371..61995384,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995371..61995384, +
3.29e-195FFCP PHASE2:Hg19::chr3:4774755..4774765,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:4774755..4774765, +
3.29e-195FFCP PHASE2:Hg19::chr17:61995480..61995499,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995480..61995499, -
3.29e-195FFCP PHASE2:Hg19::chr6:22287787..22287798,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287787..22287798, -
3.29e-195FFCP PHASE1:Hg19::chr6:22290499..22290506,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290499..22290506, +
3.29e-195FFCP PHASE2:Hg19::chr7:31003560..31003576,+#_47bedeeeae192cbe89ab07ee58e0dcb1p5@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr12:89881348..89881356,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr12:89881348..89881356, -
3.29e-195FFCP PHASE2:Hg19::chr6:22287619..22287636,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287619..22287636, -
3.29e-195FFCP PHASE1:Hg19::chrX:9528518..9528536,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chrX:9528518..9528536, +
3.29e-195FFCP PHASE2:Hg19::chr19:49519519..49519562,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@CU678753
3.29e-195FFCP PHASE1:Hg19::chr6:22287728..22287735,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287728..22287735, -
3.29e-195FFCP PHASE1:Hg19::chr17:61996393..61996421,-#_47bedeeeae192cbe89ab07ee58e0dcb1p4@CSHL1, p4@GH1
3.29e-195FFCP PHASE2:Hg19::chr2:241080084..241080093,-#_47bedeeeae192cbe89ab07ee58e0dcb1p5@OTOS
3.29e-195FFCP PHASE2:Hg19::chr17:61994613..61994649,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994613..61994649, -
3.29e-195FFCP PHASE1:Hg19::chr7:31003580..31003589,+#_47bedeeeae192cbe89ab07ee58e0dcb1p6@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr3:133115455..133115457,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:133115455..133115457, +
3.29e-195FFCP PHASE2:Hg19::chr1:240043364..240043366,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr1:240043364..240043366, +
3.29e-195FFCP PHASE2:Hg19::chr17:61995995..61996002,-#_47bedeeeae192cbe89ab07ee58e0dcb1p3@AB591020
3.29e-195FFCP PHASE2:Hg19::chr6:22290492..22290497,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290492..22290497, +
3.29e-195FFCP PHASE1:Hg19::chr17:61994797..61994839,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994797..61994839, -
3.29e-195FFCP PHASE2:Hg19::chr8:130017368..130017390,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:130017368..130017390, +
3.29e-195FFCP PHASE1:Hg19::chr6:22294718..22294725,-#_47bedeeeae192cbe89ab07ee58e0dcb1p11@PRL
3.29e-195FFCP PHASE2:Hg19::chr7:31006831..31006834,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr7:31006831..31006834, +
3.29e-195FFCP PHASE2:Hg19::chr13:78813679..78813681,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr13:78813679..78813681, -
3.29e-195FFCP PHASE2:Hg19::chr17:61995220..61995244,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995220..61995244, -
3.29e-195FFCP PHASE2:Hg19::chr6:22287720..22287725,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287720..22287725, -
3.29e-195FFCP PHASE1:Hg19::chr6:22290440..22290455,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290440..22290455, +
3.29e-195FFCP PHASE1:Hg19::chr6:22287669..22287676,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287669..22287676, -
3.29e-195FFCP PHASE1:Hg19::chr3:118521917..118521922,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:118521917..118521922, -
3.29e-195FFCP PHASE1:Hg19::chr17:61996155..61996158,-#_47bedeeeae192cbe89ab07ee58e0dcb1p5@GH1
3.29e-195FFCP PHASE2:Hg19::chr20:58401898..58401905,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr20:58401898..58401905, +
3.29e-195FFCP PHASE1:Hg19::chr4:68620100..68620112,-#_47bedeeeae192cbe89ab07ee58e0dcb1p1@GNRHR
3.29e-195FFCP PHASE1:Hg19::chr10:123959529..123959547,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr10:123959529..123959547, +
3.29e-195FFCP PHASE1:Hg19::chr5:158737729..158737738,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr5:158737729..158737738, -
3.29e-195FFCP PHASE2:Hg19::chr17:61996252..61996253,-#_47bedeeeae192cbe89ab07ee58e0dcb1p2@GH1, p3@CSHL1
3.29e-195FFCP PHASE2:Hg19::chr3:130248948..130248959,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:130248948..130248959, +
3.29e-195FFCP PHASE1:Hg19::chr17:61995410..61995414,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995410..61995414, -
3.29e-195FFCP PHASE1:Hg19::chr1:168250194..168250197,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@TBX19
3.29e-195FFCP PHASE2:Hg19::chr17:61995704..61995739,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995704..61995739, +
3.29e-195FFCP PHASE2:Hg19::chr6:22287815..22287820,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287815..22287820, -
3.29e-195FFCP PHASE2:Hg19::chr7:31003580..31003589,+#_47bedeeeae192cbe89ab07ee58e0dcb1p6@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr19:7979665..7979675,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr19:7979665..7979675, +
3.29e-195FFCP PHASE1:Hg19::chr2:7497646..7497649,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:7497646..7497649, +
3.29e-195FFCP PHASE2:Hg19::chr6:22287647..22287662,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287647..22287662, -
3.29e-195FFCP PHASE2:Hg19::chr19:2608406..2608413,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr19:2608406..2608413, -
3.29e-195FFCP PHASE2:Hg19::chr17:61994760..61994767,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994760..61994767, +
3.29e-195FFCP PHASE1:Hg19::chr12:89881337..89881342,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr12:89881337..89881342, -
3.29e-195FFCP PHASE1:Hg19::chr7:31003593..31003614,+#_47bedeeeae192cbe89ab07ee58e0dcb1p2@GHRHR
3.29e-195FFCP PHASE1:Hg19::chr17:61995906..61995914,-#_47bedeeeae192cbe89ab07ee58e0dcb1p6@AB591020
3.29e-195FFCP PHASE2:Hg19::chr17:61996018..61996019,-#_47bedeeeae192cbe89ab07ee58e0dcb1p5@AB591020
3.29e-195FFCP PHASE2:Hg19::chr6:22290499..22290506,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290499..22290506, +
3.29e-195FFCP PHASE1:Hg19::chr16:21049173..21049231,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr16:21049173..21049231, -
3.29e-195FFCP PHASE1:Hg19::chr6:22294730..22294743,-#_47bedeeeae192cbe89ab07ee58e0dcb1p6@PRL
3.29e-195FFCP PHASE1:Hg19::chr4:1352813..1352818,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr4:1352813..1352818, -
3.29e-195FFCP PHASE2:Hg19::chr17:61995371..61995384,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995371..61995384, +
3.29e-195FFCP PHASE1:Hg19::chr3:154042775..154042780,-#_47bedeeeae192cbe89ab07ee58e0dcb1p8@DHX36
3.29e-195FFCP PHASE2:Hg19::chr6:22287728..22287735,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287728..22287735, -
3.29e-195FFCP PHASE1:Hg19::chr2:25391425..25391439,-#_47bedeeeae192cbe89ab07ee58e0dcb1p10@POMC
3.29e-195FFCP PHASE1:Hg19::chr6:22290447..22290450,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290447..22290450, -
3.29e-195FFCP PHASE2:Hg19::chrX:9528518..9528536,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chrX:9528518..9528536, +
3.29e-195FFCP PHASE1:Hg19::chrX:54051809..54051811,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chrX:54051809..54051811, +
3.29e-195FFCP PHASE1:Hg19::chr2:211830430..211830435,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr2:211830430..211830435, +
3.29e-195FFCP PHASE1:Hg19::chr6:22287695..22287700,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287695..22287700, -
3.29e-195FFCP PHASE1:Hg19::chr17:61996160..61996176,-#_47bedeeeae192cbe89ab07ee58e0dcb1p3@GH1
3.29e-195FFCP PHASE1:Hg19::chr11:70178863..70178874,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr11:70178863..70178874, +
3.29e-195FFCP PHASE2:Hg19::chr17:61996393..61996421,-#_47bedeeeae192cbe89ab07ee58e0dcb1p4@CSHL1, p4@GH1
3.29e-195FFCP PHASE2:Hg19::chr6:22294718..22294725,-#_47bedeeeae192cbe89ab07ee58e0dcb1p11@PRL
3.29e-195FFCP PHASE1:Hg19::chr17:61995432..61995458,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61995432..61995458, -
3.29e-195FFCP PHASE1:Hg19::chr8:107844170..107844179,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr8:107844170..107844179, +
3.29e-195FFCP PHASE2:Hg19::chr6:22290440..22290455,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22290440..22290455, +
3.29e-195FFCP PHASE1:Hg19::chr2:25391815..25391821,-#_47bedeeeae192cbe89ab07ee58e0dcb1p13@POMC
3.29e-195FFCP PHASE1:Hg19::chr6:22292828..22292837,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22292828..22292837, -
3.29e-195FFCP PHASE1:Hg19::chr3:130248877..130248886,+#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:130248877..130248886, +
3.29e-195FFCP PHASE2:Hg19::chr7:31003593..31003614,+#_47bedeeeae192cbe89ab07ee58e0dcb1p2@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr17:61994797..61994839,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr17:61994797..61994839, -
3.29e-195FFCP PHASE2:Hg19::chr6:22287669..22287676,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287669..22287676, -
3.29e-195FFCP PHASE2:Hg19::chr3:118521917..118521922,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr3:118521917..118521922, -
3.29e-195FFCP PHASE2:Hg19::chr17:18021982..18021985,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@MYO15A
3.29e-195FFCP PHASE2:Hg19::chr4:68620100..68620112,-#_47bedeeeae192cbe89ab07ee58e0dcb1p1@GNRHR
3.29e-195FFCP PHASE1:Hg19::chr6:22287768..22287781,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr6:22287768..22287781, -
3.29e-195FFCP PHASE1:Hg19::chr12:89881348..89881356,-#_47bedeeeae192cbe89ab07ee58e0dcb1p@chr12:89881348..89881356, -
3.29e-195FFCP PHASE1:Hg19::chr7:31003621..31003641,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@GHRHR
3.29e-195FFCP PHASE2:Hg19::chr1:168250194..168250197,+#_47bedeeeae192cbe89ab07ee58e0dcb1p3@TBX19










Property "Property value" (as page type) with input value "UBPROP:0000001 "An endocrine gland derived from infundibulum of the floor of the diencephalon and an ectodermal dorsal protrusion from the buccal cavity which controls the secretion of many hormones influencing the function of various organs of the body.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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