CL:0000115
From FANTOM5_SSTAR
Name: | endothelial cell | |
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Namespace: | cell;;efo | |
Definition: | "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://63.198.234.228/OpenFMA/Endothelial%20cell.html, https://sourceforge.net/tracker/?func | |
Xrefs: |
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Synonyms: | "endotheliocyte" EXACT [] | |
Comments: | From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | CL:0000213(lining cell),CL:0002078(meso-epithelial cell) |
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Children
is a: | CL:0002139 (endothelial cell of vascular tree),CL:0002188 (glomerular endothelial cell),CL:0002262 (endothelial cell of sinusoid),CL:0002367 (trabecular meshwork cell),FF:13595-146E4 (liver sinusoidal endothelial cells, sham operation, biol_rep1),FF:13596-146E5 (liver sinusoidal endothelial cells, sham operation, biol_rep2),FF:13597-146E6 (liver sinusoidal endothelial cells, sham operation, biol_rep3),FF:13598-146E7 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep1),FF:13599-146E8 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep2),FF:13600-146E9 (liver sinusoidal endothelial cells, partial hepatectomy, 02hr, biol_rep3),FF:13601-146F1 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep1),FF:13602-146F2 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep2),FF:13603-146F3 (liver sinusoidal endothelial cells, partial hepatectomy, 30hr, biol_rep3),FF:13604-146F4 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep1),FF:13605-146F5 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep2),FF:13606-146F6 (liver sinusoidal endothelial cells, partial hepatectomy, 48hr, biol_rep3),FF:13607-146F7 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep1),FF:13608-146F8 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep2),FF:13609-146F9 (liver sinusoidal endothelial cells, partial hepatectomy, week01, biol_rep3) |
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derives from: | FF:0000046 (human endothelial cell sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 11207-116A1 (Endothelial Cells - Aortic, donor0)
- 11229-116C5 (CD14+ monocyte derived endothelial progenitor cells, donor1)
- 11236-116D3 (Endothelial Cells - Lymphatic, donor1)
- 11243-116E1 (Endothelial Cells - Umbilical vein, donor1)
- 11263-116G3 (Endothelial Cells - Aortic, donor1)
- 11264-116G4 (Endothelial Cells - Artery, donor1)
- 11265-116G5 (Endothelial Cells - Microvascular, donor1)
- 11266-116G6 (Endothelial Cells - Thoracic, donor1)
- 11267-116G7 (Endothelial Cells - Vein, donor1)
- 11310-117C5 (CD14+ monocyte derived endothelial progenitor cells, donor2)
... further results Mouse (Mus musculus)
- 11207-116A1 (Endothelial Cells - Aortic, donor0)
- 11229-116C5 (CD14+ monocyte derived endothelial progenitor cells, donor1)
- 11236-116D3 (Endothelial Cells - Lymphatic, donor1)
- 11243-116E1 (Endothelial Cells - Umbilical vein, donor1)
- 11263-116G3 (Endothelial Cells - Aortic, donor1)
- 11264-116G4 (Endothelial Cells - Artery, donor1)
- 11265-116G5 (Endothelial Cells - Microvascular, donor1)
- 11266-116G6 (Endothelial Cells - Thoracic, donor1)
- 11267-116G7 (Endothelial Cells - Vein, donor1)
- 11310-117C5 (CD14+ monocyte derived endothelial progenitor cells, donor2)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000115 (endothelial cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data