Coexpression cluster:C147
From FANTOM5_SSTAR
Full id: C147_Neutrophils_Eosinophils_CD4_CD14_CD8_Natural_Peripheral
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
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GO:0016607 | nuclear speck | 0.0203978334575988 |
GO:0045603 | positive regulation of endothelial cell differentiation | 0.0203978334575988 |
GO:0016604 | nuclear body | 0.0203978334575988 |
GO:0045601 | regulation of endothelial cell differentiation | 0.020814998759357 |
GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity | 0.020814998759357 |
GO:0045663 | positive regulation of myoblast differentiation | 0.0260160678016211 |
GO:0065008 | regulation of biological quality | 0.0320032852896189 |
GO:0031018 | endocrine pancreas development | 0.0320032852896189 |
GO:0045661 | regulation of myoblast differentiation | 0.0320032852896189 |
GO:0005885 | Arp2/3 protein complex | 0.0320032852896189 |
GO:0043229 | intracellular organelle | 0.0320032852896189 |
GO:0043226 | organelle | 0.0320032852896189 |
GO:0050796 | regulation of insulin secretion | 0.0320032852896189 |
GO:0031016 | pancreas development | 0.0371390172926794 |
GO:0045446 | endothelial cell differentiation | 0.0376086394375892 |
GO:0045766 | positive regulation of angiogenesis | 0.0376086394375892 |
GO:0006928 | cell motility | 0.0376086394375892 |
GO:0051674 | localization of cell | 0.0376086394375892 |
GO:0030073 | insulin secretion | 0.0376086394375892 |
GO:0042593 | glucose homeostasis | 0.0376086394375892 |
GO:0033500 | carbohydrate homeostasis | 0.0376086394375892 |
GO:0003779 | actin binding | 0.0376086394375892 |
GO:0046883 | regulation of hormone secretion | 0.0376086394375892 |
GO:0030833 | regulation of actin filament polymerization | 0.0376086394375892 |
GO:0002790 | peptide secretion | 0.0376086394375892 |
GO:0030072 | peptide hormone secretion | 0.0376086394375892 |
GO:0044451 | nucleoplasm part | 0.0376086394375892 |
GO:0006479 | protein amino acid methylation | 0.0376086394375892 |
GO:0008213 | protein amino acid alkylation | 0.0376086394375892 |
GO:0005654 | nucleoplasm | 0.0419733197076172 |
GO:0044424 | intracellular part | 0.0419733197076172 |
GO:0045445 | myoblast differentiation | 0.0419733197076172 |
GO:0006506 | GPI anchor biosynthetic process | 0.0419733197076172 |
GO:0006505 | GPI anchor metabolic process | 0.0419733197076172 |
GO:0030041 | actin filament polymerization | 0.0419733197076172 |
GO:0035270 | endocrine system development | 0.0419733197076172 |
GO:0046879 | hormone secretion | 0.0419733197076172 |
GO:0008092 | cytoskeletal protein binding | 0.0419733197076172 |
GO:0046489 | phosphoinositide biosynthetic process | 0.0419733197076172 |
GO:0045765 | regulation of angiogenesis | 0.0419733197076172 |
GO:0015833 | peptide transport | 0.0419733197076172 |
GO:0004715 | non-membrane spanning protein tyrosine kinase activity | 0.0419733197076172 |
GO:0048741 | skeletal muscle fiber development | 0.0419733197076172 |
GO:0048747 | muscle fiber development | 0.0419733197076172 |
GO:0044446 | intracellular organelle part | 0.0419733197076172 |
GO:0044422 | organelle part | 0.0419733197076172 |
GO:0008064 | regulation of actin polymerization and/or depolymerization | 0.0419733197076172 |
GO:0007010 | cytoskeleton organization and biogenesis | 0.0419733197076172 |
GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | 0.0419733197076172 |
GO:0043414 | biopolymer methylation | 0.0419733197076172 |
GO:0031981 | nuclear lumen | 0.0419733197076172 |
GO:0046474 | glycerophospholipid biosynthetic process | 0.0419733197076172 |
GO:0042692 | muscle cell differentiation | 0.0419733197076172 |
GO:0030832 | regulation of actin filament length | 0.0419733197076172 |
GO:0045597 | positive regulation of cell differentiation | 0.0419733197076172 |
GO:0004112 | cyclic-nucleotide phosphodiesterase activity | 0.0419733197076172 |
GO:0032535 | regulation of cellular component size | 0.0419733197076172 |
GO:0032956 | regulation of actin cytoskeleton organization and biogenesis | 0.0419733197076172 |
GO:0008283 | cell proliferation | 0.0445836578942313 |
GO:0006497 | protein amino acid lipidation | 0.0445836578942313 |
GO:0030308 | negative regulation of cell growth | 0.0445836578942313 |
GO:0045792 | negative regulation of cell size | 0.0445836578942313 |
GO:0042158 | lipoprotein biosynthetic process | 0.0445836578942313 |
GO:0051493 | regulation of cytoskeleton organization and biogenesis | 0.0445836578942313 |
GO:0033043 | regulation of organelle organization and biogenesis | 0.0445836578942313 |
GO:0051046 | regulation of secretion | 0.0462460849575835 |
GO:0008154 | actin polymerization and/or depolymerization | 0.046397908252683 |
GO:0045926 | negative regulation of growth | 0.046397908252683 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
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Ontology term | p-value | n |
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Ontology term | p-value | n |
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Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
No analysis results for this cluster
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
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