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Coexpression cluster:C2702

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Full id: C2702_anaplastic_duodenum_parietal_occipital_brain_nonsmall_temporal



Phase1 CAGE Peaks

Hg19::chr2:50549170..50549173,-p@chr2:50549170..50549173
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Hg19::chr2:50574856..50574877,-p9@NRXN1
Hg19::chr8:65285701..65285712,+p3@LOC100130155
Hg19::chr8:65291787..65291791,+p1@MIR124-2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
embryonic stem cell9.63e-085
neuronal stem cell3.94e-078
neuron8.50e-076
neuroblast8.50e-076
electrically signaling cell8.50e-076
Uber Anatomy
Ontology termp-valuen
central nervous system7.51e-5882
regional part of nervous system5.30e-5794
nervous system5.30e-5794
neural tube8.03e-5657
neural rod8.03e-5657
future spinal cord8.03e-5657
neural keel8.03e-5657
regional part of forebrain4.52e-4741
forebrain4.52e-4741
future forebrain4.52e-4741
regional part of brain4.08e-4659
neurectoderm5.39e-4690
anterior neural tube1.13e-4542
brain3.70e-4569
future brain3.70e-4569
neural plate1.30e-4386
presumptive neural plate1.30e-4386
cerebral hemisphere6.46e-4332
gray matter1.32e-4234
brain grey matter1.32e-4234
telencephalon1.70e-4234
adult organism1.80e-42115
regional part of telencephalon6.39e-4133
regional part of cerebral cortex2.28e-3522
ectoderm8.18e-35173
presumptive ectoderm8.18e-35173
cerebral cortex8.10e-3325
pallium8.10e-3325
ectoderm-derived structure1.07e-32169
neocortex2.21e-3220
pre-chordal neural plate3.43e-3161
anterior region of body1.63e-25129
craniocervical region1.63e-25129
head3.08e-25123
tube1.45e-15194
anatomical conduit4.39e-12241
basal ganglion1.89e-119
nuclear complex of neuraxis1.89e-119
aggregate regional part of brain1.89e-119
collection of basal ganglia1.89e-119
cerebral subcortex1.89e-119
gyrus2.16e-116
posterior neural tube2.93e-1115
chordal neural plate2.93e-1115
temporal lobe3.20e-117
nucleus of brain4.21e-119
neural nucleus4.21e-119
anatomical cluster5.44e-11286
embryo3.82e-10612
parietal lobe6.95e-105
occipital lobe9.84e-105
epithelium1.83e-09309
limbic system2.93e-095
cell layer3.37e-09312
organ part3.65e-09219
segmental subdivision of nervous system5.94e-0913
telencephalic nucleus2.18e-087
multi-cellular organism3.59e-08659
segmental subdivision of hindbrain9.23e-0812
hindbrain9.23e-0812
presumptive hindbrain9.23e-0812
corpus striatum1.97e-074
striatum1.97e-074
ventral part of telencephalon1.97e-074
future corpus striatum1.97e-074
organism subdivision2.39e-07365
embryonic structure4.36e-07605
developing anatomical structure4.36e-07605


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.