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UBERON:0007100

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Name:circulatory organ
Definition:"A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood[GO]." [GO:0007507]
Xrefs:
links:

ANISEED:1235302
FBbt:00003154
[1]

TADS:0000147
Synonyms: "adult heart" RELATED [FBbt:00003154]
"cardiac structure" EXACT []
"dorsal tube" NARROW [Wikipedia:Heart]
"heart" NARROW [GO:0007507]
"heart or heart like organ" EXACT []
Comments:editor note: we need to find the appropriate GO process to use for the definition - 'blood circulation' may not apply to invertebrates; 'circulatory system process' is circular. Note we cannot use a part_of-based definition as this results in the iris and all vascular elements being categorized as circulatory organs. Taxon notes: note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. "The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian". Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis
Subset: grouping_class

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0003103(compound organ)
part_of:UBERON:0001009(circulatory system)



Children

is a:UBERON:0000948 (heart)
part of:CL:0000746 (cardiac muscle cell),CL:0002494 (cardiocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0007100 (circulatory organ), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data