CL:0000057
From FANTOM5_SSTAR
Name: | fibroblast | ||
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Namespace: | efo | ||
Definition: | "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." ISBN:0517223651, MESH:A.11.329.228 | ||
Xrefs: |
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Comments: | These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | CL:0000055(non-terminally differentiated cell),CL:0002320(connective tissue cell),EFO:0000324(cell type) |
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develops_from: | CL:0000134(mesenchymal cell) |
Children
is a: | CL:0000005 (fibroblast neural crest derived),CL:0000632 (hepatic stellate cell),CL:0002334 (preadipocyte),CL:0002548 (cardiac fibroblast),CL:0002549 (fibroblast of choroid plexus),CL:0002550 (fibroblast of the conjuctiva),CL:0002552 (fibroblast of gingiva),CL:0002553 (lung fibroblast),CL:0002554 (fibroblast of lymphatic vessel),CL:0002555 (fibroblast of mammary gland),CL:0002556 (fibroblast of periodontium),CL:0002557 (fibroblast of pulmonary artery),CL:0002558 (fibroblast of villous mesenchyme),CL:0002620 (skin fibroblast),CL:1000306 (fibroblast of tunica adventitia of artery) |
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derives from: | FF:0000057 (fibroblast sample),FF:0000107 (mouse embryonic fibroblast sample),FF:0100453 (fibroblast cell line sample) |
develops from: | CL:0000135 (fibrocyte) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 10446-106F5
- 10521-107E8
- 10522-107E9
- 10575-108B8
- 10576-108B9
- 10577-108C1
- 10578-108C2
- 10579-108C3
- 10580-108C4
- 10581-108C5
... further results Mouse (Mus musculus)
- 10446-106F5
- 10521-107E8
- 10522-107E9
- 10575-108B8
- 10576-108B9
- 10577-108C1
- 10578-108C2
- 10579-108C3
- 10580-108C4
- 10581-108C5
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000057 (fibroblast), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data