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UBERON:0007616

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Name:layer of synovial tissue
Definition:"A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]." [BTO:0001338, http://www.britannica.com/EBchecked/topic/578563/synovial-tissue]
Xrefs:
links:

BTO:0001338

FMA:66762
Synonyms: "stratum synoviale" NARROW [FMA:TA]
"synovial layer" NARROW [FMA:66762]
"synovial membrane" NARROW [FMA:66762]
"synovial tissue" RELATED [BTO:0001338]

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:UBERON:0000042(serous membrane),UBERON:0002384(connective tissue)



Children

is a:UBERON:0002018 (synovial membrane of synovial joint)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0007616 (layer of synovial tissue), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
6.24e-88FFCP PHASE2:Hg19::chr7:80546293..80546302,-#_4ba04bb5ef159f5743a6c4289d8050cdp31@SEMA3C
6.24e-88FFCP PHASE1:Hg19::chr7:80546293..80546302,-#_4ba04bb5ef159f5743a6c4289d8050cdp31@SEMA3C
1.71e-66FFCP PHASE2:Hg19::chr18:22150956..22150983,+#_0c58920748ec767ed9dbb37ce5792dd3p@chr18:22150956..22150983, +
1.71e-66FFCP PHASE1:Hg19::chr18:22150956..22150983,+#_0c58920748ec767ed9dbb37ce5792dd3p@chr18:22150956..22150983, +
2.39e-66FFCP PHASE1:Hg19::chr1:172134755..172134764,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr1:172134755..172134764, +
2.39e-66FFCP PHASE1:Hg19::chr15:68117826..68117829,+#_9179be04ca5e8bfeef059cbffd2df4afp9@SKOR1
2.39e-66FFCP PHASE2:Hg19::chr1:172134755..172134764,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr1:172134755..172134764, +
2.39e-66FFCP PHASE2:Hg19::chr8:37411632..37411639,-#_9179be04ca5e8bfeef059cbffd2df4afp1@ENST00000517363
2.39e-66FFCP PHASE1:Hg19::chr8:37411632..37411639,-#_9179be04ca5e8bfeef059cbffd2df4afp1@ENST00000517363
2.39e-66FFCP PHASE2:Hg19::chr1:172134667..172134711,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr1:172134667..172134711, +
2.39e-66FFCP PHASE1:Hg19::chr1:172134667..172134711,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr1:172134667..172134711, +
2.39e-66FFCP PHASE2:Hg19::chr2:181751144..181751146,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr2:181751144..181751146, +
2.39e-66FFCP PHASE1:Hg19::chr12:130786785..130786827,-#_9179be04ca5e8bfeef059cbffd2df4afp@chr12:130786785..130786827, -
2.39e-66FFCP PHASE1:Hg19::chr1:172134736..172134739,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr1:172134736..172134739, +
2.39e-66FFCP PHASE1:Hg19::chr2:181751144..181751146,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr2:181751144..181751146, +
2.39e-66FFCP PHASE2:Hg19::chr12:130786785..130786827,-#_9179be04ca5e8bfeef059cbffd2df4afp@chr12:130786785..130786827, -
2.39e-66FFCP PHASE2:Hg19::chr1:172134736..172134739,+#_9179be04ca5e8bfeef059cbffd2df4afp@chr1:172134736..172134739, +
2.39e-66FFCP PHASE2:Hg19::chr15:68117826..68117829,+#_9179be04ca5e8bfeef059cbffd2df4afp9@SKOR1
1.68e-53FFCP PHASE1:Hg19::chr8:25337208..25337219,+#_791176a28d38f48ca045e89c2a170ce2p5@CDCA2
1.68e-53FFCP PHASE2:Hg19::chr8:25337208..25337219,+#_791176a28d38f48ca045e89c2a170ce2p5@CDCA2
2.19e-53FFCP PHASE2:Hg19::chr2:242009429..242009432,+#_5c314b46bbce52a151a050fe47c08fcap@chr2:242009429..242009432, +
2.19e-53FFCP PHASE1:Hg19::chr2:242009429..242009432,+#_5c314b46bbce52a151a050fe47c08fcap@chr2:242009429..242009432, +
2.87e-53FFCP PHASE1:Hg19::chr12:131476821..131476831,-#_c1d1ae6891579e9ad2f6577d78a207d0p@chr12:131476821..131476831, -
2.87e-53FFCP PHASE2:Hg19::chr12:131476821..131476831,-#_c1d1ae6891579e9ad2f6577d78a207d0p@chr12:131476821..131476831, -
1.22e-44FFCP PHASE2:Hg19::chrY:58884631..58884640,+#_7d591535ddc2caeeed1dde6ee472e4e7p@chrY:58884631..58884640, +
1.22e-44FFCP PHASE1:Hg19::chrY:58884631..58884640,+#_7d591535ddc2caeeed1dde6ee472e4e7p@chrY:58884631..58884640, +
1.8e-38FFCP PHASE2:Hg19::chr1:142537706..142537723,-#_2245e88174e4b8ad661f3ddad0a10a82p@chr1:142537706..142537723, -
1.8e-38FFCP PHASE1:Hg19::chr1:142537706..142537723,-#_2245e88174e4b8ad661f3ddad0a10a82p@chr1:142537706..142537723, -
1.85e-36FFCP PHASE1:Hg19::chr10:131634104..131634108,-#_f0302b3c0bc369a01e3bc21648349ed8p@chr10:131634104..131634108, -
1.85e-36FFCP PHASE2:Hg19::chr10:131634104..131634108,-#_f0302b3c0bc369a01e3bc21648349ed8p@chr10:131634104..131634108, -
3.33e-34FFCP PHASE2:Hg19::chr17:9066265..9066271,+#_0294bd4824ac9edefdb5e90b4250658fp@chr17:9066265..9066271, +
3.33e-34FFCP PHASE1:Hg19::chr17:9066265..9066271,+#_0294bd4824ac9edefdb5e90b4250658fp@chr17:9066265..9066271, +
4.27e-34FFCP PHASE1:Hg19::chr10:135140510..135140524,-#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr10:135140510..135140524, -
4.27e-34FFCP PHASE2:Hg19::chr12:54379011..54379016,+#_8d317435e8ab0b433aa9805fe4bd2d5ep15@HOXC10
4.27e-34FFCP PHASE2:Hg19::chr5:1043105..1043109,+#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr5:1043105..1043109, +
4.27e-34FFCP PHASE2:Hg19::chr15:68124311..68124318,+#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr15:68124311..68124318, +
4.27e-34FFCP PHASE2:Hg19::chr10:135140510..135140524,-#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr10:135140510..135140524, -
4.27e-34FFCP PHASE1:Hg19::chr8:78774585..78774589,-#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr8:78774585..78774589, -
4.27e-34FFCP PHASE1:Hg19::chr5:1043105..1043109,+#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr5:1043105..1043109, +
4.27e-34FFCP PHASE1:Hg19::chr12:130646534..130646542,+#_8d317435e8ab0b433aa9805fe4bd2d5ep5@FZD10
4.27e-34FFCP PHASE1:Hg19::chr15:68124311..68124318,+#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr15:68124311..68124318, +
4.27e-34FFCP PHASE2:Hg19::chr8:78774585..78774589,-#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr8:78774585..78774589, -
4.27e-34FFCP PHASE2:Hg19::chr12:130646534..130646542,+#_8d317435e8ab0b433aa9805fe4bd2d5ep5@FZD10
4.27e-34FFCP PHASE2:Hg19::chr4:139010162..139010169,+#_8d317435e8ab0b433aa9805fe4bd2d5ep1@LOC641364
4.27e-34FFCP PHASE1:Hg19::chr4:139010162..139010169,+#_8d317435e8ab0b433aa9805fe4bd2d5ep1@LOC641364
4.27e-34FFCP PHASE2:Hg19::chr8:37411648..37411657,-#_8d317435e8ab0b433aa9805fe4bd2d5ep1@ENST00000519738
4.27e-34FFCP PHASE1:Hg19::chr8:37411648..37411657,-#_8d317435e8ab0b433aa9805fe4bd2d5ep1@ENST00000519738
4.27e-34FFCP PHASE2:Hg19::chr15:68118244..68118272,+#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr15:68118244..68118272, +
4.27e-34FFCP PHASE1:Hg19::chr15:68118244..68118272,+#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr15:68118244..68118272, +
4.27e-34FFCP PHASE2:Hg19::chr12:91435143..91435151,-#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr12:91435143..91435151, -
4.27e-34FFCP PHASE1:Hg19::chr12:54379011..54379016,+#_8d317435e8ab0b433aa9805fe4bd2d5ep15@HOXC10
4.27e-34FFCP PHASE1:Hg19::chr12:91435143..91435151,-#_8d317435e8ab0b433aa9805fe4bd2d5ep@chr12:91435143..91435151, -
5.51e-34FFCP PHASE2:Hg19::chr15:89402148..89402159,+#_1bc33b9555977ebd5d959d0f8cf5e5fbp6@ACAN
5.51e-34FFCP PHASE1:Hg19::chr15:89402148..89402159,+#_1bc33b9555977ebd5d959d0f8cf5e5fbp6@ACAN
5.96e-34FFCP PHASE1:Hg19::chr12:54366780..54366791,+#_747479f710ac026ab1adf3433c94f0bcp12@HOXC11
5.96e-34FFCP PHASE2:Hg19::chr12:54366780..54366791,+#_747479f710ac026ab1adf3433c94f0bcp12@HOXC11
5.96e-34FFCP PHASE2:Hg19::chr15:68117844..68117858,+#_747479f710ac026ab1adf3433c94f0bcp3@SKOR1
5.96e-34FFCP PHASE1:Hg19::chr15:68117844..68117858,+#_747479f710ac026ab1adf3433c94f0bcp3@SKOR1
5.96e-34FFCP PHASE2:Hg19::chr17:63705566..63705573,-#_747479f710ac026ab1adf3433c94f0bcp@chr17:63705566..63705573, -
5.96e-34FFCP PHASE1:Hg19::chr17:63705566..63705573,-#_747479f710ac026ab1adf3433c94f0bcp@chr17:63705566..63705573, -
5.96e-34FFCP PHASE1:Hg19::chr1:172145683..172145699,+#_747479f710ac026ab1adf3433c94f0bcp@chr1:172145683..172145699, +
5.96e-34FFCP PHASE2:Hg19::chr1:172145683..172145699,+#_747479f710ac026ab1adf3433c94f0bcp@chr1:172145683..172145699, +
5.96e-34FFCP PHASE2:Hg19::chr13:73102090..73102097,-#_747479f710ac026ab1adf3433c94f0bcp@chr13:73102090..73102097, -
5.96e-34FFCP PHASE1:Hg19::chr13:73102090..73102097,-#_747479f710ac026ab1adf3433c94f0bcp@chr13:73102090..73102097, -
5.96e-34FFCP PHASE2:Hg19::chr6:42072877..42072881,-#_747479f710ac026ab1adf3433c94f0bcp11@C6orf132
5.96e-34FFCP PHASE1:Hg19::chr6:42072877..42072881,-#_747479f710ac026ab1adf3433c94f0bcp11@C6orf132
7.7e-34FFCP PHASE2:Hg19::chrY:13450855..13450866,+#_cffcf865861eb1b2f88aaf1483cb2f13p@chrY:13450855..13450866, +
7.7e-34FFCP PHASE1:Hg19::chrY:13450855..13450866,+#_cffcf865861eb1b2f88aaf1483cb2f13p@chrY:13450855..13450866, +
1.46e-31FFCP PHASE2:Hg19::chr19:18718172..18718197,+#_ad27575092fcf6f43a25c22e5808aa37p@chr19:18718172..18718197, +
1.46e-31FFCP PHASE1:Hg19::chr19:18718172..18718197,+#_ad27575092fcf6f43a25c22e5808aa37p@chr19:18718172..18718197, +
1.71e-30FFCP PHASE2:Hg19::chr21:39821025..39821046,-#_c24624fdbd4882090b133bad9b655de2p9@ERG
1.71e-30FFCP PHASE1:Hg19::chr21:39821025..39821046,-#_c24624fdbd4882090b133bad9b655de2p9@ERG
2.3e-30FFCP PHASE1:Hg19::chr1:186273262..186273282,+#_462200d9cf149a0c7b9fa39bc1f412d6p@chr1:186273262..186273282, +
2.3e-30FFCP PHASE1:Hg19::chr15:89402048..89402061,+#_462200d9cf149a0c7b9fa39bc1f412d6p8@ACAN
2.3e-30FFCP PHASE2:Hg19::chr1:186273262..186273282,+#_462200d9cf149a0c7b9fa39bc1f412d6p@chr1:186273262..186273282, +
2.3e-30FFCP PHASE2:Hg19::chr15:89402048..89402061,+#_462200d9cf149a0c7b9fa39bc1f412d6p8@ACAN
7.54e-30FFCP PHASE1:Hg19::chr1:186276427..186276448,+#_284761ba742126d7015ed678e6e8c62bp@chr1:186276427..186276448, +
7.54e-30FFCP PHASE2:Hg19::chr1:186276427..186276448,+#_284761ba742126d7015ed678e6e8c62bp@chr1:186276427..186276448, +
8.12e-28FFCP PHASE2:Hg19::chr7:80373118..80373135,-#_f8c192613333686f73a604d598872f4dp21@SEMA3C
8.12e-28FFCP PHASE1:Hg19::chr7:80373118..80373135,-#_f8c192613333686f73a604d598872f4dp21@SEMA3C
1.39e-27FFCP PHASE2:Hg19::chr20:48160907..48160918,-#_456aaec1854f8f6f661c87dd7ea14d8ap@chr20:48160907..48160918, -
1.39e-27FFCP PHASE1:Hg19::chr20:48160907..48160918,-#_456aaec1854f8f6f661c87dd7ea14d8ap@chr20:48160907..48160918, -
1.82e-27FFCP PHASE1:Hg19::chr1:142537912..142537938,-#_dee9056171bdfbd4aef6b8b1f7024f97p@chr1:142537912..142537938, -
1.82e-27FFCP PHASE2:Hg19::chr20:43343646..43343655,+#_dee9056171bdfbd4aef6b8b1f7024f97p7@WISP2
1.82e-27FFCP PHASE1:Hg19::chr20:43343646..43343655,+#_dee9056171bdfbd4aef6b8b1f7024f97p7@WISP2
1.82e-27FFCP PHASE2:Hg19::chr3:156877038..156877058,-#_dee9056171bdfbd4aef6b8b1f7024f97p35@CCNL1
1.82e-27FFCP PHASE1:Hg19::chr3:156877038..156877058,-#_dee9056171bdfbd4aef6b8b1f7024f97p35@CCNL1
1.82e-27FFCP PHASE2:Hg19::chr1:142537912..142537938,-#_dee9056171bdfbd4aef6b8b1f7024f97p@chr1:142537912..142537938, -
2.08e-27FFCP PHASE2:Hg19::chr1:142539672..142539687,-#_31449de498bb15faabcc7949d294d829p@chr1:142539672..142539687, -
2.08e-27FFCP PHASE1:Hg19::chr1:142539672..142539687,-#_31449de498bb15faabcc7949d294d829p@chr1:142539672..142539687, -
2.08e-27FFCP PHASE2:Hg19::chr6:1609602..1609636,-#_31449de498bb15faabcc7949d294d829p@chr6:1609602..1609636, -
2.08e-27FFCP PHASE1:Hg19::chr6:1609602..1609636,-#_31449de498bb15faabcc7949d294d829p@chr6:1609602..1609636, -
2.38e-27FFCP PHASE2:Hg19::chr21:39705323..39705334,-#_114982e3e6ce383e1e2d1b9bcdf18b8fp2@ENST00000436845
2.38e-27FFCP PHASE1:Hg19::chr21:39705323..39705334,-#_114982e3e6ce383e1e2d1b9bcdf18b8fp2@ENST00000436845
3.11e-27FFCP PHASE2:Hg19::chr16:15680784..15680797,+#_040659ff6975b9377d3384ab48eedfd8p@chr16:15680784..15680797, +
3.11e-27FFCP PHASE1:Hg19::chr6:31918397..31918412,+#_040659ff6975b9377d3384ab48eedfd8p15@CFB
3.11e-27FFCP PHASE1:Hg19::chr16:15680784..15680797,+#_040659ff6975b9377d3384ab48eedfd8p@chr16:15680784..15680797, +
3.11e-27FFCP PHASE2:Hg19::chr6:31918397..31918412,+#_040659ff6975b9377d3384ab48eedfd8p15@CFB
4.07e-27FFCP PHASE1:Hg19::chr8:70476088..70476102,+#_6926cabea427a3b8cf1b7e598aa29d0dp21@SULF1
4.07e-27FFCP PHASE2:Hg19::chr8:70476088..70476102,+#_6926cabea427a3b8cf1b7e598aa29d0dp21@SULF1

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