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UBERON:0000995

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Name:uterus
Definition:"a major female hormone-responsive reproductive sex organ of most mammals including humans. One end, the cervix, opens into the vagina, while the other is connected to one or both fallopian tubes, depending on the species. It is within the uterus that the fetus develops during gestation, usually developing completely in placental mammals such as humans and partially in marsupials such as kangaroos and opossums. Two uteruses usually form initially in a female fetus, and in placental mammals they may partially or completely fuse into a single uterus depending on the species. In many species with two uteruses, only one is functional. Humans and other higher primates such as chimpanzees, along with horses, usually have a single completely fused uterus, although in some individuals the uteruses may not have completely fused[WP]." [Wikipedia:Uterus]
Xrefs:
links:

BTO:0001424
EFO:0000975
EMAPA:29915
EV:0100113
FMA:17558
GAID:172
galen:Uterus
[ Female_reproductive_system_lateral_nolabel.png Female_reproductive_system_lateral_nolabel.png]
[ 200px-Female_anatomy.png 200px-Female_anatomy.png]
MA:0000389
MAT:0000127
MESH:A.05.360.319.679
MIAA:0000127
ncithesaurus:Uterus
OpenCyc:Mx4rvViojJwpEbGdrcN5Y29ycA
SCTID:181452004

VHOG:0001137
Synonyms: "uterine horn" RELATED []
"uterine horns" RELATED []
"womb" RELATED [BTO:0001424]
Comments:Most animals that lay eggs, such as birds and reptiles, have an oviduct instead of a uterus. In monotremes, mammals which lay eggs and include the platypus, either the term uterus or oviduct is used to describe the same organ, but the egg does not develop a placenta within the mother and thus does not receive further nourishment after formation and fertilization. Marsupials have two uteruses, each of which connect to a lateral vagina and which both use a third, middle "vagina" which functions as the birth canal. Marsupial embryos form a choriovitelline "placenta" (which can be thought of as something between a monotreme egg and a "true" placenta), in which the egg's yolk sac supplies a large part of the embryo's nutrition but also attaches to the uterine wall and takes nutrients from the mother's bloodstream.
Alt_id: UBERON:FBbt_00004924-FMA_17558-MA_0000389-MIAA_0000127-WBbt_0006760
Subset: organ_slim
uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0003975(internal female genitalia)
develops_from:UBERON:0005795(embryonic uterus)
part_of:UBERON:0000474(female reproductive system)



Children

derives from:FF:0010100 (human uterus - adult sample),FF:0011389 (mouse uterus- adult pregnant day19 sample),FF:0011440 (mouse uterus- adult sample),FF:0100658 (uterine adenocarcinoma cell sample),FF:0102694 (leiomyoma cell sample)
develops from:UBERON:0001987 (placenta)
part of:UBERON:0000002 (uterine cervix),UBERON:0000459 (uterine wall),CL:0002149 (epithelial cell of uterus),CL:0002601 (uterine smooth muscle cell),UBERON:0006955 (uterine epithelium)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000995 (uterus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
2.83e-65FFCP PHASE2:Mm9::chr6:121306890..121306895,+#_ad50a65be387ed68d586e3b0b51e3782p11@Slc6a12
2.83e-65FFCP PHASE2:Mm9::chr2:131680870..131680891,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131680870..131680891, -
2.83e-65FFCP PHASE1:Mm9::chr6:121306916..121306921,+#_ad50a65be387ed68d586e3b0b51e3782p12@Slc6a12
2.83e-65FFCP PHASE1:Mm9::chr16:20316875..20316878,-#_ad50a65be387ed68d586e3b0b51e3782p@chr16:20316875..20316878, -
2.83e-65FFCP PHASE2:Mm9::chrX:51027816..51027821,+#_ad50a65be387ed68d586e3b0b51e3782p2@4930502E18Rik
2.83e-65FFCP PHASE1:Mm9::chr9:40297262..40297271,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297262..40297271, -
2.83e-65FFCP PHASE2:Mm9::chr7:150952911..150952917,-#_ad50a65be387ed68d586e3b0b51e3782p3@Mrgprg
2.83e-65FFCP PHASE2:Mm9::chr12:8339024..8339034,+#_ad50a65be387ed68d586e3b0b51e3782p@chr12:8339024..8339034, +
2.83e-65FFCP PHASE1:Mm9::chr11:46564064..46564079,+#_ad50a65be387ed68d586e3b0b51e3782p2@Havcr1
2.83e-65FFCP PHASE2:Mm9::chr6:48855132..48855142,+#_ad50a65be387ed68d586e3b0b51e3782p11@Abp1
2.83e-65FFCP PHASE2:Mm9::chr10:115614273..115614299,+#_ad50a65be387ed68d586e3b0b51e3782p17@Ptprr
2.83e-65FFCP PHASE1:Mm9::chr14:56857569..56857584,-#_ad50a65be387ed68d586e3b0b51e3782p@chr14:56857569..56857584, -
2.83e-65FFCP PHASE1:Mm9::chr7:150952890..150952901,-#_ad50a65be387ed68d586e3b0b51e3782p2@Mrgprg
2.83e-65FFCP PHASE2:Mm9::chr5:112904886..112904895,-#_ad50a65be387ed68d586e3b0b51e3782p6@Sez6l
2.83e-65FFCP PHASE1:Mm9::chr2:131680870..131680891,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131680870..131680891, -
2.83e-65FFCP PHASE1:Mm9::chrX:51027816..51027821,+#_ad50a65be387ed68d586e3b0b51e3782p2@4930502E18Rik
2.83e-65FFCP PHASE2:Mm9::chr16:92596391..92596400,-#_ad50a65be387ed68d586e3b0b51e3782p@chr16:92596391..92596400, -
2.83e-65FFCP PHASE2:Mm9::chr2:131681104..131681114,+#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131681104..131681114, +
2.83e-65FFCP PHASE1:Mm9::chr9:40297312..40297323,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297312..40297323, -
2.83e-65FFCP PHASE2:Mm9::chr16:20316875..20316878,-#_ad50a65be387ed68d586e3b0b51e3782p@chr16:20316875..20316878, -
2.83e-65FFCP PHASE2:Mm9::chr9:40297262..40297271,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297262..40297271, -
2.83e-65FFCP PHASE1:Mm9::chr6:48854959..48854972,+#_ad50a65be387ed68d586e3b0b51e3782p6@Abp1
2.83e-65FFCP PHASE2:Mm9::chr4:140462693..140462700,-#_ad50a65be387ed68d586e3b0b51e3782p@chr4:140462693..140462700, -
2.83e-65FFCP PHASE1:Mm9::chr7:150952911..150952917,-#_ad50a65be387ed68d586e3b0b51e3782p3@Mrgprg
2.83e-65FFCP PHASE2:Mm9::chr17:29601992..29602002,+#_ad50a65be387ed68d586e3b0b51e3782p@chr17:29601992..29602002, +
2.83e-65FFCP PHASE1:Mm9::chr4:140462693..140462700,-#_ad50a65be387ed68d586e3b0b51e3782p@chr4:140462693..140462700, -
2.83e-65FFCP PHASE1:Mm9::chr13:27434787..27434799,-#_ad50a65be387ed68d586e3b0b51e3782p@chr13:27434787..27434799, -
2.83e-65FFCP PHASE2:Mm9::chr5:112905373..112905419,+#_ad50a65be387ed68d586e3b0b51e3782p@chr5:112905373..112905419, +
2.83e-65FFCP PHASE1:Mm9::chr2:166407469..166407519,-#_ad50a65be387ed68d586e3b0b51e3782p4@Prex1
2.83e-65FFCP PHASE2:Mm9::chr6:48854959..48854972,+#_ad50a65be387ed68d586e3b0b51e3782p6@Abp1
2.83e-65FFCP PHASE1:Mm9::chr10:21130385..21130393,-#_ad50a65be387ed68d586e3b0b51e3782p@chr10:21130385..21130393, -
2.83e-65FFCP PHASE1:Mm9::chr14:14765101..14765107,+#_ad50a65be387ed68d586e3b0b51e3782p1@ENSMUST00000159275, p1@uc007sgd.1
2.83e-65FFCP PHASE1:Mm9::chr2:131681104..131681114,+#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131681104..131681114, +
2.83e-65FFCP PHASE1:Mm9::chr12:8339007..8339020,+#_ad50a65be387ed68d586e3b0b51e3782p@chr12:8339007..8339020, +
2.83e-65FFCP PHASE1:Mm9::chr9:40297334..40297345,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297334..40297345, -
2.83e-65FFCP PHASE2:Mm9::chr9:40297312..40297323,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297312..40297323, -
2.83e-65FFCP PHASE2:Mm9::chr14:56857569..56857584,-#_ad50a65be387ed68d586e3b0b51e3782p@chr14:56857569..56857584, -
2.83e-65FFCP PHASE2:Mm9::chr14:14765101..14765107,+#_ad50a65be387ed68d586e3b0b51e3782p1@ENSMUST00000159275, p1@uc007sgd.1
2.83e-65FFCP PHASE2:Mm9::chr13:61036161..61036172,-#_ad50a65be387ed68d586e3b0b51e3782p@chr13:61036161..61036172, -
2.83e-65FFCP PHASE1:Mm9::chr2:131681357..131681366,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131681357..131681366, -
2.83e-65FFCP PHASE2:Mm9::chr2:131681357..131681366,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131681357..131681366, -
2.83e-65FFCP PHASE2:Mm9::chr7:129057811..129057817,+#_ad50a65be387ed68d586e3b0b51e3782p@chr7:129057811..129057817, +
2.83e-65FFCP PHASE1:Mm9::chr17:29601992..29602002,+#_ad50a65be387ed68d586e3b0b51e3782p@chr17:29601992..29602002, +
2.83e-65FFCP PHASE1:Mm9::chr5:112904886..112904895,-#_ad50a65be387ed68d586e3b0b51e3782p6@Sez6l
2.83e-65FFCP PHASE1:Mm9::chr6:121306890..121306895,+#_ad50a65be387ed68d586e3b0b51e3782p11@Slc6a12
2.83e-65FFCP PHASE1:Mm9::chr13:61036161..61036172,-#_ad50a65be387ed68d586e3b0b51e3782p@chr13:61036161..61036172, -
2.83e-65FFCP PHASE2:Mm9::chr7:150952861..150952867,-#_ad50a65be387ed68d586e3b0b51e3782p4@Mrgprg
2.83e-65FFCP PHASE2:Mm9::chr6:97777247..97777258,+#_ad50a65be387ed68d586e3b0b51e3782p@chr6:97777247..97777258, +
2.83e-65FFCP PHASE1:Mm9::chr2:131685562..131685563,-#_ad50a65be387ed68d586e3b0b51e3782p2@Erv3
2.83e-65FFCP PHASE2:Mm9::chr2:131685562..131685563,-#_ad50a65be387ed68d586e3b0b51e3782p2@Erv3
2.83e-65FFCP PHASE2:Mm9::chr2:124475078..124475084,+#_ad50a65be387ed68d586e3b0b51e3782p@chr2:124475078..124475084, +
2.83e-65FFCP PHASE1:Mm9::chr12:8339024..8339034,+#_ad50a65be387ed68d586e3b0b51e3782p@chr12:8339024..8339034, +
2.83e-65FFCP PHASE2:Mm9::chr11:46564064..46564079,+#_ad50a65be387ed68d586e3b0b51e3782p2@Havcr1
2.83e-65FFCP PHASE2:Mm9::chr6:121306916..121306921,+#_ad50a65be387ed68d586e3b0b51e3782p12@Slc6a12
2.83e-65FFCP PHASE1:Mm9::chr10:115614018..115614024,-#_ad50a65be387ed68d586e3b0b51e3782p@chr10:115614018..115614024, -
2.83e-65FFCP PHASE1:Mm9::chr9:40297346..40297350,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297346..40297350, -
2.83e-65FFCP PHASE2:Mm9::chr9:40297334..40297345,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297334..40297345, -
2.83e-65FFCP PHASE1:Mm9::chr2:169512387..169512392,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:169512387..169512392, -
2.83e-65FFCP PHASE1:Mm9::chr6:48855132..48855142,+#_ad50a65be387ed68d586e3b0b51e3782p11@Abp1
2.83e-65FFCP PHASE1:Mm9::chr7:129057811..129057817,+#_ad50a65be387ed68d586e3b0b51e3782p@chr7:129057811..129057817, +
2.83e-65FFCP PHASE2:Mm9::chr13:61036176..61036186,-#_ad50a65be387ed68d586e3b0b51e3782p@chr13:61036176..61036186, -
2.83e-65FFCP PHASE1:Mm9::chr2:131681543..131681554,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131681543..131681554, -
2.83e-65FFCP PHASE2:Mm9::chr10:21130385..21130393,-#_ad50a65be387ed68d586e3b0b51e3782p@chr10:21130385..21130393, -
2.83e-65FFCP PHASE2:Mm9::chr2:131681543..131681554,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:131681543..131681554, -
2.83e-65FFCP PHASE1:Mm9::chr5:112905373..112905419,+#_ad50a65be387ed68d586e3b0b51e3782p@chr5:112905373..112905419, +
2.83e-65FFCP PHASE2:Mm9::chr2:166407469..166407519,-#_ad50a65be387ed68d586e3b0b51e3782p4@Prex1
2.83e-65FFCP PHASE1:Mm9::chr13:61036176..61036186,-#_ad50a65be387ed68d586e3b0b51e3782p@chr13:61036176..61036186, -
2.83e-65FFCP PHASE1:Mm9::chr13:27437553..27437554,+#_ad50a65be387ed68d586e3b0b51e3782p3@Prl8a2
2.83e-65FFCP PHASE2:Mm9::chr7:150952890..150952901,-#_ad50a65be387ed68d586e3b0b51e3782p2@Mrgprg
2.83e-65FFCP PHASE2:Mm9::chr12:8339007..8339020,+#_ad50a65be387ed68d586e3b0b51e3782p@chr12:8339007..8339020, +
2.83e-65FFCP PHASE2:Mm9::chr13:27437553..27437554,+#_ad50a65be387ed68d586e3b0b51e3782p3@Prl8a2
2.83e-65FFCP PHASE2:Mm9::chr10:115614018..115614024,-#_ad50a65be387ed68d586e3b0b51e3782p@chr10:115614018..115614024, -
2.83e-65FFCP PHASE1:Mm9::chr2:124475078..124475084,+#_ad50a65be387ed68d586e3b0b51e3782p@chr2:124475078..124475084, +
2.83e-65FFCP PHASE1:Mm9::chr10:115614273..115614299,+#_ad50a65be387ed68d586e3b0b51e3782p17@Ptprr
2.83e-65FFCP PHASE1:Mm9::chr7:150952861..150952867,-#_ad50a65be387ed68d586e3b0b51e3782p4@Mrgprg
2.83e-65FFCP PHASE1:Mm9::chr6:97777247..97777258,+#_ad50a65be387ed68d586e3b0b51e3782p@chr6:97777247..97777258, +
2.83e-65FFCP PHASE2:Mm9::chr9:40297346..40297350,-#_ad50a65be387ed68d586e3b0b51e3782p@chr9:40297346..40297350, -
2.83e-65FFCP PHASE1:Mm9::chr16:92596391..92596400,-#_ad50a65be387ed68d586e3b0b51e3782p@chr16:92596391..92596400, -
2.83e-65FFCP PHASE2:Mm9::chr13:27434787..27434799,-#_ad50a65be387ed68d586e3b0b51e3782p@chr13:27434787..27434799, -
2.83e-65FFCP PHASE2:Mm9::chr2:169512387..169512392,-#_ad50a65be387ed68d586e3b0b51e3782p@chr2:169512387..169512392, -
9.34e-51FFCP PHASE2:Mm9::chr14:56853487..56853492,-#_aa12b0fc9c688783716c15965a5118c3p1@Gzmc, p2@Gzmf
9.34e-51FFCP PHASE1:Mm9::chr14:56853487..56853492,-#_aa12b0fc9c688783716c15965a5118c3p1@Gzmc, p2@Gzmf
5.32e-50FFCP PHASE1:Mm9::chr3:79594253..79594277,-#_65ab536b3942fda95dd23da518e62941p@chr3:79594253..79594277, -
5.32e-50FFCP PHASE2:Mm9::chr3:79594253..79594277,-#_65ab536b3942fda95dd23da518e62941p@chr3:79594253..79594277, -
1.6e-49FFCP PHASE2:Mm9::chr2:131681565..131681576,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr2:131681565..131681576, -
1.6e-49FFCP PHASE1:Mm9::chr6:122448778..122448784,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr6:122448778..122448784, -
1.6e-49FFCP PHASE2:Mm9::chr14:56739460..56739464,-#_3ee085a15ba7da45b27f8e8e1307542ap2@Gzme
1.6e-49FFCP PHASE2:Mm9::chr16:92596358..92596371,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr16:92596358..92596371, -
1.6e-49FFCP PHASE1:Mm9::chr18:64859703..64859710,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr18:64859703..64859710, -
1.6e-49FFCP PHASE1:Mm9::chr13:27437563..27437570,+#_3ee085a15ba7da45b27f8e8e1307542ap2@Prl8a2
1.6e-49FFCP PHASE2:Mm9::chr2:35288301..35288317,-#_3ee085a15ba7da45b27f8e8e1307542ap11@Ggta1
1.6e-49FFCP PHASE2:Mm9::chr14:56830260..56830267,-#_3ee085a15ba7da45b27f8e8e1307542ap1@Gzmf
1.6e-49FFCP PHASE1:Mm9::chr15:81606702..81606709,+#_3ee085a15ba7da45b27f8e8e1307542ap7@Zc3h7b
1.6e-49FFCP PHASE1:Mm9::chr2:131681188..131681226,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr2:131681188..131681226, -
1.6e-49FFCP PHASE2:Mm9::chr2:131681188..131681226,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr2:131681188..131681226, -
1.6e-49FFCP PHASE2:Mm9::chr6:121306897..121306910,+#_3ee085a15ba7da45b27f8e8e1307542ap8@Slc6a12
1.6e-49FFCP PHASE2:Mm9::chr13:27437563..27437570,+#_3ee085a15ba7da45b27f8e8e1307542ap2@Prl8a2
1.6e-49FFCP PHASE1:Mm9::chr2:131681267..131681280,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr2:131681267..131681280, -
1.6e-49FFCP PHASE2:Mm9::chr2:131681267..131681280,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr2:131681267..131681280, -
1.6e-49FFCP PHASE2:Mm9::chr6:122448778..122448784,-#_3ee085a15ba7da45b27f8e8e1307542ap@chr6:122448778..122448784, -