MCL coexpression mm9:264

Phase1 CAGE Peaks

	Short description
Mm9::chr10:115726435..115726454,+	p@chr10:115726435..115726454 +
Mm9::chr10:115783936..115783945,+	p@chr10:115783936..115783945 +
Mm9::chr10:115809917..115809921,+	p@chr10:115809917..115809921 +
Mm9::chr10:12103662..12103666,-	p@chr10:12103662..12103666 -
Mm9::chr11:30000318..30000322,-	p@chr11:30000318..30000322 -
Mm9::chr11:30148502..30148509,-	p@chr11:30148502..30148509 -
Mm9::chr11:30153416..30153420,-	p@chr11:30153416..30153420 -
Mm9::chr13:100017650..100017662,+	p@chr13:100017650..100017662 +
Mm9::chr13:115846729..115846733,-	p@chr13:115846729..115846733 -
Mm9::chr16:85542827..85542835,-	p@chr16:85542827..85542835 -
Mm9::chr16:95581011..95581024,-	p@chr16:95581011..95581024 -
Mm9::chr17:13016269..13016283,+	p@chr17:13016269..13016283 +
Mm9::chr17:43592386..43592398,+	p@chr17:43592386..43592398 +
Mm9::chr17:43592580..43592605,+	p@chr17:43592580..43592605 +
Mm9::chr17:47898459..47898487,+	p@chr17:47898459..47898487 +
Mm9::chr17:67475291..67475294,-	p@chr17:67475291..67475294 -
Mm9::chr17:75919962..75919967,+	p@chr17:75919962..75919967 +
Mm9::chr19:21867742..21867746,+	p@chr19:21867742..21867746 +
Mm9::chr1:11175335..11175339,+	p@chr1:11175335..11175339 +
Mm9::chr1:152644349..152644352,-	p@chr1:152644349..152644352 -
Mm9::chr1:164764434..164764438,-	p13@Fmo1
Mm9::chr1:59931940..59931964,+	p@chr1:59931940..59931964 +
Mm9::chr2:84247734..84247745,-	p@chr2:84247734..84247745 -
Mm9::chr4:3706358..3706404,+	p@chr4:3706358..3706404 +
Mm9::chr4:57906800..57906812,+	p@chr4:57906800..57906812 +
Mm9::chr4:94487460..94487476,+	p@chr4:94487460..94487476 +
Mm9::chr5:65546218..65546229,+	p@chr5:65546218..65546229 +
Mm9::chr5:65546334..65546342,+	p@chr5:65546334..65546342 +
Mm9::chr6:97469086..97469090,-	p@chr6:97469086..97469090 -
Mm9::chr7:108156311..108156321,-	p@chr7:108156311..108156321 -
Mm9::chr8:37649789..37649792,-	p@chr8:37649789..37649792 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	0.0276058484853454
GO:0007527	adult somatic muscle development	0.0276058484853454
GO:0030036	actin cytoskeleton organization and biogenesis	0.0276058484853454
GO:0030029	actin filament-based process	0.0276058484853454
GO:0007525	somatic muscle development	0.0276058484853454
GO:0007184	SMAD protein nuclear translocation	0.0306698039093664
GO:0004499	flavin-containing monooxygenase activity	0.0328569034321639
GO:0003779	actin binding	0.0358052730957127
GO:0007167	enzyme linked receptor protein signaling pathway	0.0367876359540371
GO:0051018	protein kinase A binding	0.0367876359540371
GO:0007182	common-partner SMAD protein phosphorylation	0.0376195958943488
GO:0050661	NADP binding	0.0393980510213329
GO:0008092	cytoskeletal protein binding	0.0393980510213329
GO:0016010	dystrophin-associated glycoprotein complex	0.0393980510213329
GO:0031594	neuromuscular junction	0.039831442055262
GO:0000060	protein import into nucleus, translocation	0.0404043651360832
GO:0051016	barbed-end actin filament capping	0.0404043651360832
GO:0030835	negative regulation of actin filament depolymerization	0.0404043651360832
GO:0051693	actin filament capping	0.0404043651360832
GO:0005624	membrane fraction	0.0404043651360832
GO:0007010	cytoskeleton organization and biogenesis	0.0404043651360832
GO:0030834	regulation of actin filament depolymerization	0.0404043651360832
GO:0030042	actin filament depolymerization	0.0404043651360832
GO:0007165	signal transduction	0.0404043651360832
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen	0.0404043651360832
GO:0031227	intrinsic to endoplasmic reticulum membrane	0.0406118255343949
GO:0000267	cell fraction	0.0421358455079084
GO:0005605	basal lamina	0.0421358455079084
GO:0007154	cell communication	0.0421358455079084
GO:0008064	regulation of actin polymerization and/or depolymerization	0.0421358455079084
GO:0051261	protein depolymerization	0.0421358455079084
GO:0032535	regulation of cellular component size	0.0421358455079084
GO:0032956	regulation of actin cytoskeleton organization and biogenesis	0.0421358455079084
GO:0030832	regulation of actin filament length	0.0421358455079084
GO:0051129	negative regulation of cellular component organization and biogenesis	0.0421358455079084
GO:0051493	regulation of cytoskeleton organization and biogenesis	0.0421358455079084
GO:0033043	regulation of organelle organization and biogenesis	0.0421358455079084
GO:0008154	actin polymerization and/or depolymerization	0.0469985389384137
GO:0007015	actin filament organization	0.0469985389384137

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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