MCL coexpression mm9:286

Phase1 CAGE Peaks

	Short description
Mm9::chr10:23943345..23943407,+	p1@Moxd1
Mm9::chr11:113612623..113612641,-	p5@Cdc42ep4
Mm9::chr11:113613098..113613120,-	p1@Cdc42ep4
Mm9::chr11:45940767..45940771,+	p@chr11:45940767..45940771 +
Mm9::chr11:94104253..94104270,-	p3@Wfikkn2
Mm9::chr13:99124757..99124764,+	p@chr13:99124757..99124764 +
Mm9::chr16:30599803..30599820,+	p1@Fam43a
Mm9::chr19:54120233..54120243,+	p4@Adra2a
Mm9::chr19:6532264..6532286,-	p4@ENSMUST00000149574
Mm9::chr19:7025211..7025226,+	p8@Bad
Mm9::chr2:163317341..163317353,+	p@chr2:163317341..163317353 +
Mm9::chr2:30701003..30701028,+	p6@Prrx2
Mm9::chr2:93482426..93482434,+	p3@Alx4
Mm9::chr2:93482464..93482491,+	p1@Alx4
Mm9::chr4:138641482..138641515,-	p@chr4:138641482..138641515 -
Mm9::chr4:138648873..138648892,-	p1@Nbl1
Mm9::chr4:138648925..138648936,-	p2@Nbl1
Mm9::chr6:84537931..84537980,-	p@chr6:84537931..84537980 -
Mm9::chr6:84537985..84538004,-	p@chr6:84537985..84538004 -
Mm9::chr6:84538594..84538603,-	p6@Cyp26b1
Mm9::chr6:84538625..84538639,-	p2@Cyp26b1
Mm9::chr6:84538689..84538700,-	p5@Cyp26b1
Mm9::chr6:84538957..84538977,-	p1@Cyp26b1
Mm9::chr8:113329722..113329748,-	p3@Il34
Mm9::chr8:113329763..113329852,-	p1@Il34
Mm9::chr9:43915755..43915801,+	p@chr9:43915755..43915801 +
Mm9::chr9:57385390..57385441,+	p1@2310046O06Rik
Mm9::chr9:57389282..57389286,+	p@chr9:57389282..57389286 +
Mm9::chr9:58884009..58884028,-	p2@Neo1

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0035107	appendage morphogenesis	0.0495393326676861
GO:0035108	limb morphogenesis	0.0495393326676861
GO:0060173	limb development	0.0495393326676861
GO:0048736	appendage development	0.0495393326676861
GO:0032502	developmental process	0.0495393326676861
GO:0004938	alpha2-adrenergic receptor activity	0.0495393326676861
GO:0048856	anatomical structure development	0.0495393326676861
GO:0004500	dopamine beta-monooxygenase activity	0.0495393326676861
GO:0048384	retinoic acid receptor signaling pathway	0.0495393326676861
GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	0.0495393326676861
GO:0045579	positive regulation of B cell differentiation	0.0495393326676861
GO:0045296	cadherin binding	0.0495393326676861
GO:0050839	cell adhesion molecule binding	0.0495393326676861
GO:0003002	regionalization	0.0495393326676861
GO:0007275	multicellular organismal development	0.0495393326676861
GO:0004936	alpha-adrenergic receptor activity	0.0495393326676861
GO:0007517	muscle development	0.0495393326676861
GO:0000768	syncytium formation by plasma membrane fusion	0.0495393326676861
GO:0007520	myoblast fusion	0.0495393326676861
GO:0014902	myotube differentiation	0.0495393326676861
GO:0008191	metalloendopeptidase inhibitor activity	0.0495393326676861
GO:0006949	syncytium formation	0.0495393326676861
GO:0042573	retinoic acid metabolic process	0.0495393326676861
GO:0045577	regulation of B cell differentiation	0.0495393326676861
GO:0006548	histidine catabolic process	0.0495393326676861
GO:0007140	male meiosis	0.0495393326676861
GO:0009077	histidine family amino acid catabolic process	0.0495393326676861
GO:0050789	regulation of biological process	0.0495393326676861
GO:0009954	proximal/distal pattern formation	0.0495393326676861
GO:0006547	histidine metabolic process	0.0495393326676861
GO:0009075	histidine family amino acid metabolic process	0.0495393326676861
GO:0005021	vascular endothelial growth factor receptor activity	0.0495393326676861

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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