MCL coexpression mm9:361

Phase1 CAGE Peaks

	Short description
Mm9::chr14:12385975..12385998,+	p4@Ptprg
Mm9::chr14:12386013..12386028,+	p6@Ptprg
Mm9::chr18:35862724..35862735,-	p3@Dnajc18
Mm9::chr18:35862738..35862753,-	p1@Dnajc18
Mm9::chr18:38761259..38761273,+	p2@Arhgap26
Mm9::chr18:64676201..64676219,-	p2@Nars
Mm9::chr19:45438234..45438321,+	p1@Btrc
Mm9::chr2:116946596..116946618,+	p2@Spred1
Mm9::chr2:116946787..116946885,+	p1@Spred1
Mm9::chr2:121692654..121692733,+	p1@Casc4
Mm9::chr2:80421372..80421385,-	p5@Nckap1
Mm9::chr2:80421391..80421423,-	p2@Nckap1
Mm9::chr2:80421429..80421450,-	p3@Nckap1
Mm9::chr3:63780031..63780057,+	p2@Gmps
Mm9::chr7:25039763..25039831,+	p1@Zfp108
Mm9::chr7:99890142..99890225,+	p1@Rab30
Mm9::chrX:108810678..108810736,-	p1@Hdx
Mm9::chrX:131252469..131252480,+	p2@Armcx1
Mm9::chrX:131252482..131252557,+	p1@Armcx1
Mm9::chrX:133275818..133275846,-	p1@Morf4l2
Mm9::chrX:72341224..72341261,+	p2@Dkc1
Mm9::chrX:92906980..92907024,+	p2@Zc3h12b

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016836	hydro-lyase activity	0.030392264285323
GO:0045175	basal protein localization	0.030392264285323
GO:0030950	establishment and/or maintenance of actin cytoskeleton polarity	0.030392264285323
GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	0.030392264285323
GO:0003921	GMP synthase activity	0.030392264285323
GO:0032879	regulation of localization	0.030392264285323
GO:0030952	establishment and/or maintenance of cytoskeleton polarity	0.030392264285323
GO:0032880	regulation of protein localization	0.030392264285323
GO:0016835	carbon-oxygen lyase activity	0.0321103085972842
GO:0007509	mesoderm migration	0.037392542559238
GO:0008078	mesodermal cell migration	0.037392542559238
GO:0007354	zygotic determination of anterior/posterior axis, embryo	0.037392542559238
GO:0006421	asparaginyl-tRNA aminoacylation	0.037392542559238
GO:0016874	ligase activity	0.0391467307563428
GO:0005173	stem cell factor receptor binding	0.0418606881635714
GO:0006177	GMP biosynthetic process	0.0418606881635714
GO:0006399	tRNA metabolic process	0.0418606881635714
GO:0048570	notochord morphogenesis	0.0418606881635714
GO:0046037	GMP metabolic process	0.0418606881635714
GO:0048617	embryonic foregut morphogenesis	0.0418606881635714
GO:0010172	embryonic body morphogenesis	0.0418606881635714
GO:0000154	rRNA modification	0.0418606881635714
GO:0030519	snoRNP binding	0.0418606881635714
GO:0007440	foregut morphogenesis	0.0418606881635714
GO:0000578	embryonic axis specification	0.0418606881635714
GO:0031119	tRNA pseudouridine synthesis	0.0418606881635714
GO:0008595	determination of anterior/posterior axis, embryo	0.0418606881635714
GO:0010171	body morphogenesis	0.0418606881635714
GO:0007351	tripartite regional subdivision	0.0418606881635714
GO:0007350	blastoderm segmentation	0.0440654891570662
GO:0048611	embryonic ectodermal gut development	0.0440654891570662
GO:0048613	embryonic ectodermal gut morphogenesis	0.0440654891570662
GO:0006400	tRNA modification	0.0440654891570662
GO:0030903	notochord development	0.0440654891570662
GO:0045176	apical protein localization	0.0440654891570662
GO:0016829	lyase activity	0.0440654891570662
GO:0042074	cell migration involved in gastrulation	0.0440654891570662
GO:0050821	protein stabilization	0.0440654891570662
GO:0048558	embryonic gut morphogenesis	0.0440654891570662
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	0.0440654891570662
GO:0004730	pseudouridylate synthase activity	0.0440654891570662
GO:0016879	ligase activity, forming carbon-nitrogen bonds	0.0440654891570662
GO:0043170	macromolecule metabolic process	0.0440654891570662
GO:0048340	paraxial mesoderm morphogenesis	0.0440654891570662
GO:0000188	inactivation of MAPK activity	0.0440654891570662
GO:0031647	regulation of protein stability	0.0440654891570662
GO:0001522	pseudouridine synthesis	0.0440654891570662
GO:0048557	embryonic digestive tract morphogenesis	0.0440654891570662
GO:0008105	asymmetric protein localization	0.0440654891570662
GO:0044238	primary metabolic process	0.0440654891570662
GO:0044237	cellular metabolic process	0.0440654891570662
GO:0007439	ectodermal gut development	0.0440654891570662
GO:0009168	purine ribonucleoside monophosphate biosynthetic process	0.0440654891570662
GO:0009127	purine nucleoside monophosphate biosynthetic process	0.0440654891570662
GO:0048567	ectodermal gut morphogenesis	0.0440654891570662
GO:0048547	gut morphogenesis	0.0451697183144582
GO:0009167	purine ribonucleoside monophosphate metabolic process	0.0451697183144582
GO:0009126	purine nucleoside monophosphate metabolic process	0.0451697183144582
GO:0009948	anterior/posterior axis specification	0.0451697183144582
GO:0048546	digestive tract morphogenesis	0.0491768801296322
GO:0048339	paraxial mesoderm development	0.0491768801296322
GO:0035050	embryonic heart tube development	0.0491768801296322
GO:0048566	embryonic gut development	0.0491768801296322
GO:0009156	ribonucleoside monophosphate biosynthetic process	0.0491768801296322

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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