MCL coexpression mm9:2119

Phase1 CAGE Peaks

	Short description
Mm9::chr14:75531033..75531048,+	p16@Lcp1
Mm9::chr16:43235969..43235989,+	p20@Zbtb20
Mm9::chr16:43236037..43236050,+	p35@Zbtb20
Mm9::chr8:114154225..114154244,-	p1@Ldhd

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016898	oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor	0.0051498383827316
GO:0008720	D-lactate dehydrogenase activity	0.0051498383827316
GO:0004458	D-lactate dehydrogenase (cytochrome) activity	0.0051498383827316
GO:0001891	phagocytic cup	0.00772433434609092
GO:0004457	lactate dehydrogenase activity	0.0154461295096576
GO:0051017	actin filament bundle formation	0.0334519460528467
GO:0005884	actin filament	0.0370630103427486
GO:0051015	actin filament binding	0.0370630103427486
GO:0001726	ruffle	0.0370630103427486
GO:0006754	ATP biosynthetic process	0.0370630103427486
GO:0006753	nucleoside phosphate metabolic process	0.0370630103427486
GO:0046034	ATP metabolic process	0.0370630103427486
GO:0007015	actin filament organization	0.0370630103427486
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	0.0370630103427486
GO:0009201	ribonucleoside triphosphate biosynthetic process	0.0370630103427486
GO:0009145	purine nucleoside triphosphate biosynthetic process	0.0370630103427486
GO:0009142	nucleoside triphosphate biosynthetic process	0.0370630103427486
GO:0009205	purine ribonucleoside triphosphate metabolic process	0.0370630103427486
GO:0009199	ribonucleoside triphosphate metabolic process	0.0370630103427486
GO:0009144	purine nucleoside triphosphate metabolic process	0.0370630103427486
GO:0006752	group transfer coenzyme metabolic process	0.0370630103427486
GO:0009141	nucleoside triphosphate metabolic process	0.0370630103427486
GO:0009152	purine ribonucleotide biosynthetic process	0.0370630103427486
GO:0050660	FAD binding	0.0370630103427486
GO:0009260	ribonucleotide biosynthetic process	0.0370630103427486
GO:0009150	purine ribonucleotide metabolic process	0.0370630103427486
GO:0006164	purine nucleotide biosynthetic process	0.0370630103427486
GO:0009259	ribonucleotide metabolic process	0.0384779555486205
GO:0006163	purine nucleotide metabolic process	0.0389781624273876
GO:0031252	leading edge	0.0389781624273876
GO:0009108	coenzyme biosynthetic process	0.0411792677516855
GO:0051188	cofactor biosynthetic process	0.0461077196418848

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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