MCL coexpression mm9:1235

Phase1 CAGE Peaks

	Short description
Mm9::chr10:13219340..13219354,+	p5@Fuca2
Mm9::chr3:105707295..105707341,+	p2@Adora3
Mm9::chr6:128995911..128995924,+	p2@Klrb1f
Mm9::chr6:128995928..128995950,+	p1@Klrb1f
Mm9::chr9:124016683..124016698,+	p3@Ccr2
Mm9::chr9:124018349..124018363,+	p@chr9:124018349..124018363 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0001613	A3 adenosine receptor activity, G-protein coupled	0.0119787813528358
GO:0004560	alpha-L-fucosidase activity	0.0119787813528358
GO:0015928	fucosidase activity	0.0119787813528358
GO:0001609	adenosine receptor activity, G-protein coupled	0.0269433988885493
GO:0016493	C-C chemokine receptor activity	0.0448355887464724
GO:0019957	C-C chemokine binding	0.0448355887464724
GO:0001637	G-protein chemoattractant receptor activity	0.0448355887464724
GO:0004950	chemokine receptor activity	0.0448355887464724
GO:0019233	sensory perception of pain	0.0448355887464724
GO:0019956	chemokine binding	0.0448355887464724
GO:0001608	nucleotide receptor activity, G-protein coupled	0.0460749217967857
GO:0045028	purinergic nucleotide receptor activity, G-protein coupled	0.0460749217967857
GO:0016502	nucleotide receptor activity	0.0460749217967857
GO:0001614	purinergic nucleotide receptor activity	0.0460749217967857

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
foregut	6.51e-08	80
hemolymphoid system	8.19e-07	48
immune system	8.19e-07	48

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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