MCL coexpression mm9:685

Phase1 CAGE Peaks

	Short description
Mm9::chr10:13272805..13272867,-	p1@Pex3
Mm9::chr18:50287923..50287987,+	p2@Hsd17b4
Mm9::chr2:154429394..154429429,-	p1@Pxmp4
Mm9::chr3:121517837..121517869,-	p6@Abcd3
Mm9::chr3:121518055..121518071,-	p2@Abcd3
Mm9::chr3:121518078..121518127,-	p1@Abcd3
Mm9::chr3:121518333..121518424,-	p3@Abcd3
Mm9::chr5:3596306..3596393,+	p1@Pex1
Mm9::chr9:106350960..106350986,+	p2@Abhd14b
Mm9::chrX:125082958..125083011,-	p@chrX:125082958..125083011 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0042579	microbody	5.06892505140933e-07
GO:0005777	peroxisome	5.06892505140933e-07
GO:0031903	microbody membrane	0.000345601928474774
GO:0005778	peroxisomal membrane	0.000345601928474774
GO:0044439	peroxisomal part	0.000345601928474774
GO:0044438	microbody part	0.000345601928474774
GO:0060009	Sertoli cell development	0.00633946670214681
GO:0060008	Sertoli cell differentiation	0.0110925471601167
GO:0005779	integral to peroxisomal membrane	0.0158399854089115
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	0.0158399854089115
GO:0043231	intracellular membrane-bound organelle	0.0158399854089115
GO:0043227	membrane-bound organelle	0.0158399854089115
GO:0005498	sterol carrier activity	0.0158399854089115
GO:0031231	intrinsic to peroxisomal membrane	0.0158399854089115
GO:0000038	very-long-chain fatty acid metabolic process	0.0177383537688552
GO:0043229	intracellular organelle	0.0259288222538381
GO:0043226	organelle	0.0259288222538381
GO:0006635	fatty acid beta-oxidation	0.031996890041192
GO:0032934	sterol binding	0.0326401294846484
GO:0008584	male gonad development	0.037637252877947
GO:0019395	fatty acid oxidation	0.0421532680548443
GO:0007031	peroxisome organization and biogenesis	0.0442427498574792
GO:0046546	development of primary male sexual characteristics	0.0442427498574792
GO:0046661	male sex differentiation	0.047837920275482
GO:0044444	cytoplasmic part	0.047837920275482
GO:0005737	cytoplasm	0.0480276401506857
GO:0044424	intracellular part	0.0480276401506857

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
intestine	6.73e-10	31
exocrine gland	2.20e-09	25
exocrine system	2.20e-09	25
digestive tract diverticulum	1.71e-08	23
sac	1.71e-08	23
trunk region element	3.40e-08	79
endoderm-derived structure	4.25e-08	118
endoderm	4.25e-08	118
presumptive endoderm	4.25e-08	118
liver	5.01e-08	22
epithelial sac	5.01e-08	22
digestive gland	5.01e-08	22
epithelium of foregut-midgut junction	5.01e-08	22
anatomical boundary	5.01e-08	22
hepatobiliary system	5.01e-08	22
foregut-midgut junction	5.01e-08	22
hepatic diverticulum	5.01e-08	22
liver primordium	5.01e-08	22
septum transversum	5.01e-08	22
liver bud	5.01e-08	22
adult organism	6.30e-08	51
digestive system	7.04e-08	116
digestive tract	7.04e-08	116
primitive gut	7.04e-08	116
gastrointestinal system	1.25e-07	47
trunk	1.44e-07	90
mucosa	1.79e-07	15
subdivision of digestive tract	3.35e-07	114

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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