UBERON:0002067

Name:	dermis
Definition:	"The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]." [Wikipedia:Dermis, ZFIN:curator]
Xrefs:	Expandlinks: AAO:0000128 BTO:0000294 EFO:0000953 EV:0100154 FMA:70323 GAID:1321 MA:0000152 MAT:0000153 MESH:A.17.815.180 MIAA:0000153 ncithesaurus:Dermis SCTID:361696001 TAO:0001119 VHOG:0000108 XAO:0000217 ZFA:0001119
Synonyms:	"corium" RELATED [BTO:0000294] "cutis" RELATED [BTO:0000294] "vertebrate dermis" EXACT []
Comments:	Editor notes: Consider adding a layer-of-skin grouping class for all skin layers
Alt_id:	UBERON:FMA_70323-MA_0000152-MIAA_0000153-XAO_0000217-ZFA_0001119
Subset:	uberon_slim vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	UBERON:0004923(organ component layer)
develops_from:	UBERON:0003077(paraxial mesoderm),UBERON:0003104(mesenchyme),UBERON:0004016(dermatome),UBERON:0010083(future dermis)
part_of:	UBERON:0002097(skin of body),UBERON:0002199(integument)

Children

develops from:	UBERON:0004756 (dermal skeletal element)
part of:	UBERON:0001992 (papillary layer of dermis),CL:0002551 (fibroblast of dermis)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology

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Human (Homo sapiens)

• 11269-116G9 (Fibroblast - Dermal, donor1)
• 11271-116H2 (Hair Follicle Dermal Papilla Cells, donor1)
• 11346-117G5 (Fibroblast - Dermal, donor2)
• 11348-117G7 (Hair Follicle Dermal Papilla Cells, donor2)
• 11418-118F5 (Fibroblast - Dermal, donor3)
• 11420-118F7 (Hair Follicle Dermal Papilla Cells, donor3)
• 11450-119A1 (Fibroblast - Dermal, donor4)
• 11454-119A5 (Fibroblast - Dermal, donor5)
• 11458-119A9 (Fibroblast - Dermal, donor6)

Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002067 (dermis), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
1.31e-68	FFCP PHASE2:Hg19::chr1:45087872..45087892,+	p@chr1:45087872..45087892, +
1.31e-68	FFCP PHASE1:Hg19::chr1:45087872..45087892,+	p@chr1:45087872..45087892, +
9.25e-50	FFCP PHASE1:Hg19::chr7:107707064..107707079,-	p@chr7:107707064..107707079, -
9.25e-50	FFCP PHASE2:Hg19::chr7:107707064..107707079,-	p@chr7:107707064..107707079, -
9.25e-50	FFCP PHASE1:Hg19::chr7:107707083..107707099,-	p@chr7:107707083..107707099, -
9.25e-50	FFCP PHASE2:Hg19::chr7:107707083..107707099,-	p@chr7:107707083..107707099, -
9.89e-40	FFCP PHASE1:Hg19::chr10:124254447..124254458,-	p@chr10:124254447..124254458, -
9.89e-40	FFCP PHASE2:Hg19::chr10:124254447..124254458,-	p@chr10:124254447..124254458, -
1.21e-39	FFCP PHASE1:Hg19::chr1:10228206..10228218,+	p@chr1:10228206..10228218, +
1.21e-39	FFCP PHASE2:Hg19::chr1:10228206..10228218,+	p@chr1:10228206..10228218, +
5.08e-38	FFCP PHASE1:Hg19::chr6:5498703..5498727,+	p@chr6:5498703..5498727, +
5.08e-38	FFCP PHASE2:Hg19::chr6:5498703..5498727,+	p@chr6:5498703..5498727, +
2.83e-35	FFCP PHASE2:Hg19::chr8:128387795..128387801,+	p@chr8:128387795..128387801, +
2.83e-35	FFCP PHASE1:Hg19::chr8:128387795..128387801,+	p@chr8:128387795..128387801, +
1.55e-33	FFCP PHASE2:Hg19::chr1:45088343..45088354,+	p@chr1:45088343..45088354, +
1.55e-33	FFCP PHASE1:Hg19::chr1:45088343..45088354,+	p@chr1:45088343..45088354, +
5.64e-29	FFCP PHASE2:Hg19::chr7:98258032..98258045,+	p@chr7:98258032..98258045, +
5.64e-29	FFCP PHASE1:Hg19::chr7:98258032..98258045,+	p@chr7:98258032..98258045, +
7.57e-28	FFCP PHASE1:Hg19::chr10:31071229..31071236,+	p@chr10:31071229..31071236, +
7.57e-28	FFCP PHASE2:Hg19::chr10:31071229..31071236,+	p@chr10:31071229..31071236, +
1.12e-26	FFCP PHASE1:Hg19::chr5:33794920..33794939,-	p@chr5:33794920..33794939, -
1.12e-26	FFCP PHASE2:Hg19::chr5:33794920..33794939,-	p@chr5:33794920..33794939, -
1.47e-26	FFCP PHASE2:Hg19::chr21:47405899..47405911,+	p@chr21:47405899..47405911, +
1.47e-26	FFCP PHASE1:Hg19::chr21:47405899..47405911,+	p@chr21:47405899..47405911, +
1.5e-25	FFCP PHASE2:Hg19::chr4:89454373..89454379,-	p@chr4:89454373..89454379, -
1.5e-25	FFCP PHASE2:Hg19::chr17:38174999..38175001,+	p8@CASC3
1.5e-25	FFCP PHASE1:Hg19::chr4:89454373..89454379,-	p@chr4:89454373..89454379, -
1.5e-25	FFCP PHASE1:Hg19::chr17:38174999..38175001,+	p8@CASC3
2.99e-25	FFCP PHASE2:Hg19::chr8:141656896..141656918,-	p@chr8:141656896..141656918, -
2.99e-25	FFCP PHASE1:Hg19::chr8:141656896..141656918,-	p@chr8:141656896..141656918, -
3.17e-25	FFCP PHASE1:Hg19::chr2:95983133..95983144,+	p@chr2:95983133..95983144, +
3.17e-25	FFCP PHASE2:Hg19::chr2:95983133..95983144,+	p@chr2:95983133..95983144, +
2.03e-24	FFCP PHASE1:Hg19::chr5:33794876..33794902,-	p@chr5:33794876..33794902, -
2.03e-24	FFCP PHASE2:Hg19::chr5:33794876..33794902,-	p@chr5:33794876..33794902, -
2.4e-24	FFCP PHASE2:Hg19::chr5:174252830..174252847,+	p@chr5:174252830..174252847, +
2.4e-24	FFCP PHASE1:Hg19::chr5:174252830..174252847,+	p@chr5:174252830..174252847, +
2.92e-24	FFCP PHASE2:Hg19::chr4:127699583..127699608,-	p@chr4:127699583..127699608, -
2.92e-24	FFCP PHASE1:Hg19::chr4:127699583..127699608,-	p@chr4:127699583..127699608, -
1.68e-23	FFCP PHASE2:Hg19::chr4:127876558..127876592,-	p1@ENST00000515428
1.68e-23	FFCP PHASE1:Hg19::chr4:127876558..127876592,-	p1@ENST00000515428
2.62e-23	FFCP PHASE1:Hg19::chr7:127963997..127964004,-	p@chr7:127963997..127964004, -
2.62e-23	FFCP PHASE2:Hg19::chr7:127963997..127964004,-	p@chr7:127963997..127964004, -
3.32e-23	FFCP PHASE1:Hg19::chr17:813116..813132,+	p@chr17:813116..813132, +
3.32e-23	FFCP PHASE2:Hg19::chr17:813116..813132,+	p@chr17:813116..813132, +
6.41e-23	FFCP PHASE2:Hg19::chr16:85617034..85617043,-	p@chr16:85617034..85617043, -
6.41e-23	FFCP PHASE1:Hg19::chr16:85617034..85617043,-	p@chr16:85617034..85617043, -
7.17e-23	FFCP PHASE1:Hg19::chr5:177652352..177652356,-	p6@AGXT2L2
7.17e-23	FFCP PHASE2:Hg19::chr5:177652352..177652356,-	p6@AGXT2L2
7.17e-23	FFCP PHASE2:Hg19::chr5:174252850..174252859,+	p@chr5:174252850..174252859, +
7.17e-23	FFCP PHASE1:Hg19::chr5:174252850..174252859,+	p@chr5:174252850..174252859, +
4.19e-22	FFCP PHASE1:Hg19::chr5:33794904..33794916,-	p@chr5:33794904..33794916, -
4.19e-22	FFCP PHASE2:Hg19::chr5:33794904..33794916,-	p@chr5:33794904..33794916, -
3.14e-21	FFCP PHASE2:Hg19::chr11:122051600..122051617,+	p@chr11:122051600..122051617, +
3.14e-21	FFCP PHASE1:Hg19::chr11:122051600..122051617,+	p@chr11:122051600..122051617, +
7.71e-21	FFCP PHASE1:Hg19::chr21:36208749..36208768,+	p@chr21:36208749..36208768, +
7.71e-21	FFCP PHASE2:Hg19::chr21:36208749..36208768,+	p@chr21:36208749..36208768, +
8.88e-21	FFCP PHASE2:Hg19::chr20:940152..940156,-	p@chr20:940152..940156, -
8.88e-21	FFCP PHASE1:Hg19::chr20:940152..940156,-	p@chr20:940152..940156, -
9.8e-21	FFCP PHASE2:Hg19::chr18:52969844..52969895,-	p27@TCF4
9.8e-21	FFCP PHASE1:Hg19::chr18:52969844..52969895,-	p27@TCF4
1.24e-20	FFCP PHASE2:Hg19::chr1:45087902..45087912,+	p@chr1:45087902..45087912, +
1.24e-20	FFCP PHASE1:Hg19::chr1:45087902..45087912,+	p@chr1:45087902..45087912, +
1.29e-20	FFCP PHASE1:Hg19::chr12:66036219..66036262,-	p1@ENST00000544557
1.29e-20	FFCP PHASE2:Hg19::chr12:66036219..66036262,-	p1@ENST00000544557
1.32e-20	FFCP PHASE2:Hg19::chr7:152549181..152549213,+	p@chr7:152549181..152549213, +
1.32e-20	FFCP PHASE1:Hg19::chr7:152549181..152549213,+	p@chr7:152549181..152549213, +
1.73e-20	FFCP PHASE1:Hg19::chr1:119530682..119530692,-	p10@TBX15
1.73e-20	FFCP PHASE2:Hg19::chr1:119530682..119530692,-	p10@TBX15
2.11e-20	FFCP PHASE2:Hg19::chr17:73682761..73682766,+	p@chr17:73682761..73682766, +
2.11e-20	FFCP PHASE1:Hg19::chr17:73682761..73682766,+	p@chr17:73682761..73682766, +
4.35e-19	FFCP PHASE1:Hg19::chr14:38371323..38371347,-	p1@ENST00000554257, p1@uc001wuk.1
4.35e-19	FFCP PHASE2:Hg19::chr14:38371323..38371347,-	p1@ENST00000554257, p1@uc001wuk.1
4.67e-19	FFCP PHASE2:Hg19::chr21:47404148..47404163,+	p@chr21:47404148..47404163, +
4.67e-19	FFCP PHASE1:Hg19::chr21:47404148..47404163,+	p@chr21:47404148..47404163, +
5.29e-19	FFCP PHASE2:Hg19::chr4:5754385..5754405,+	p3@EVC
5.29e-19	FFCP PHASE1:Hg19::chr4:5754385..5754405,+	p3@EVC
1.22e-18	FFCP PHASE1:Hg19::chr2:177022022..177022060,+	p@chr2:177022022..177022060, +
1.22e-18	FFCP PHASE2:Hg19::chr2:177022022..177022060,+	p@chr2:177022022..177022060, +
1.35e-18	FFCP PHASE2:Hg19::chr12:2163623..2163634,+	p@chr12:2163623..2163634, +
1.35e-18	FFCP PHASE2:Hg19::chr12:5198401..5198415,+	p@chr12:5198401..5198415, +
1.35e-18	FFCP PHASE1:Hg19::chr12:5198401..5198415,+	p@chr12:5198401..5198415, +
1.35e-18	FFCP PHASE1:Hg19::chr12:2163623..2163634,+	p@chr12:2163623..2163634, +
1.51e-17	FFCP PHASE1:Hg19::chr2:201474023..201474035,+	p5@AOX1
1.51e-17	FFCP PHASE2:Hg19::chr2:201474023..201474035,+	p5@AOX1
3.53e-17	FFCP PHASE2:Hg19::chr12:66036083..66036098,-	p3@ENST00000539653
3.53e-17	FFCP PHASE1:Hg19::chr12:66036083..66036098,-	p3@ENST00000539653
4.17e-17	FFCP PHASE2:Hg19::chrX:118362928..118362933,+	p@chrX:118362928..118362933, +
4.17e-17	FFCP PHASE1:Hg19::chrX:118362928..118362933,+	p@chrX:118362928..118362933, +
4.92e-17	FFCP PHASE2:Hg19::chr4:81159520..81159523,+	p@chr4:81159520..81159523, +
4.92e-17	FFCP PHASE1:Hg19::chr4:81159520..81159523,+	p@chr4:81159520..81159523, +
7.89e-17	FFCP PHASE1:Hg19::chr2:177502906..177502920,-	p2@ENST00000295549, p2@uc002ukz.1
7.89e-17	FFCP PHASE2:Hg19::chr2:177502906..177502920,-	p2@ENST00000295549, p2@uc002ukz.1
8.61e-17	FFCP PHASE1:Hg19::chr1:85987126..85987173,-	p@chr1:85987126..85987173, -
8.61e-17	FFCP PHASE2:Hg19::chr1:85987126..85987173,-	p@chr1:85987126..85987173, -
8.66e-17	FFCP PHASE2:Hg19::chr3:139000423..139000454,+	p3@MRPS22
8.66e-17	FFCP PHASE1:Hg19::chr3:139000423..139000454,+	p3@MRPS22
9.03e-17	FFCP PHASE2:Hg19::chr17:46627545..46627560,+	p@chr17:46627545..46627560, +
9.03e-17	FFCP PHASE1:Hg19::chr17:46627545..46627560,+	p@chr17:46627545..46627560, +
1.05e-16	FFCP PHASE2:Hg19::chr20:4451008..4451026,-	p@chr20:4451008..4451026, -
1.05e-16	FFCP PHASE1:Hg19::chr20:4451008..4451026,-	p@chr20:4451008..4451026, -

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