CL:0000556
From FANTOM5_SSTAR
Name: | megakaryocyte | |
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Namespace: | cell | |
Definition: | "A giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm." [ISBN:0721601464, MESH:D008533] | |
Xrefs: |
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Synonyms: |
"megacaryocyte" EXACT [] "megalocaryocyte" EXACT [] "megalokaryocyte" EXACT [] | |
Comments: | Megakaryocytes are reportedly CD181-positive and CD182-positive. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | CL:0000414(),CL:0000763(myeloid cell) |
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disjoint_from: | CL:0000764(erythroid lineage cell) |
develops_from: | CL:0000553(megakaryocyte progenitor cell) |
part_of: | UBERON:0002371(bone marrow) |
Children
is a: | CL:0002027 (CD9-positive, CD41-positive megakaryocyte cell),FF:0101549 (megakaryocytic cell line) |
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derives from: | FF:0011468 (mouse CD41-positive megakaryocyte control sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 10761-110E5
- 11774-124A1 (CD41+ megakaryocyte cancer, donor1)
- 11775-124A2 (CD41+ megakaryocyte control, donor1)
- 11776-124A3 (CD41+ megakaryocyte cancer, donor2)
- 11777-124A4 (CD41+ megakaryocyte control, donor2)
- 11778-124A5 (CD41+ megakaryocyte cancer, donor3)
- 11779-124A6 (CD41+ megakaryocyte control, donor3)
Mouse (Mus musculus)
- 10761-110E5
- 11774-124A1 (CD41+ megakaryocyte cancer, donor1)
- 11775-124A2 (CD41+ megakaryocyte control, donor1)
- 11776-124A3 (CD41+ megakaryocyte cancer, donor2)
- 11777-124A4 (CD41+ megakaryocyte control, donor2)
- 11778-124A5 (CD41+ megakaryocyte cancer, donor3)
- 11779-124A6 (CD41+ megakaryocyte control, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000556 (megakaryocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data