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CL:0000624

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Name:CD4-positive, alpha-beta T cell
Namespace:cell
Definition:"A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor." [GOC:add, ISBN:0781735149]
Synonyms: "CD4-positive, alpha-beta T lymphocyte" EXACT []
"CD4-positive, alpha-beta T-cell" EXACT []
"CD4-positive, alpha-beta T-lymphocyte" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:CL:0000791(mature alpha-beta T cell)
disjoint_from:CL:0000625(CD8-positive, alpha-beta T cell)



Children


is a:CL:0000792 (CD4-positive, CD25-positive, alpha-beta regulatory T cell),CL:0000895 (naive thymus-derived CD4-positive, alpha-beta T cell),CL:0000896 (activated CD4-positive, alpha-beta T cell),CL:0000897 (CD4-positive, alpha-beta memory T cell),CL:0002436 (mature CD4 single-positive thymocyte)
derives from:FF:0000031 (CD4-positive T cell sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.


Human (Homo sapiens)

  • 11225-116C1 (CD4+ T Cells, donor1)
  • 11306-117C1 (CD4+ T Cells, donor2)
  • 11382-118B5 (CD4+ T Cells, donor3)
  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11814-124E5 (CD4+CD25+ regulatory T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))

... further results Mouse (Mus musculus)

  • 11225-116C1 (CD4+ T Cells, donor1)
  • 11306-117C1 (CD4+ T Cells, donor2)
  • 11382-118B5 (CD4+ T Cells, donor3)
  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11814-124E5 (CD4+CD25+ regulatory T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000624 (CD4-positive, alpha-beta T cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data