CL:0002057

Name:	CD14-positive, CD16-negative classical monocyte
Namespace:	FANTOM
Definition:	"A monocyte that is CD14-positive, CD16-negative, CD64-positive, CD163-positive," [GOC:tfm, PMID:15615263, PMID:1706877, PMID:19689341]
Comments:	Markers are associated with human monocytes.
Created by:	tmeehan
Creation date:	2010-06-05T08:25:41Z

Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

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Parents

is_a:	CL:0000860(classical monocyte),CL:0001054(CD14-positive monocyte)

Children

derives from:

FF:0011101 (human CD14-positive monocytes - mock treated sample),FF:0011102 (human CD14-positive monocytes - treated with B-glucan sample),FF:0011103 (human CD14-positive monocytes - treated with BCG sample),FF:0011104 (human CD14-positive monocytes - treated with Candida sample),FF:0011105 (human CD14-positive monocytes - treated with Cryptococcus sample),FF:0011106 (human CD14-positive monocytes - treated with Group A streptococci sample),FF:0011108 (human CD14-positive monocytes - treated with lipopolysaccharide sample),FF:0011109 (human CD14-positive monocytes - treated with Salmonella sample),FF:0011111 (human CD14-positive CD16-negative Monocytes sample),FF:0011443 (CD14-positive monocytes - treated with IFN + N-hexane sample),FF:0011444 (CD14-positive monocytes - treated with Trehalose dimycolate (TDM) sample)

develops from:

CL:0002397 (CD14-positive, CD16-positive monocyte)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

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Human (Homo sapiens)

• 11788-124B6 (CD14+CD16- Monocytes, donor1)
• 11799-124C8 (CD14+CD16- Monocytes, donor2)
• 11857-125A3
• 11858-125A4
• 11859-125A5
• 11860-125A6 (CD14+ monocytes - treated with BCG, donor1)
• 11861-125A7 (CD14+ monocytes - treated with IFN + N-hexane, donor1)
• 11862-125A8 (CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor1)
• 11863-125A9 (CD14+ monocytes - mock treated, donor1)
• 11864-125B1 (CD14+ monocytes - treated with Group A streptococci, donor1)

... further results Mouse (Mus musculus)

• 11788-124B6 (CD14+CD16- Monocytes, donor1)
• 11799-124C8 (CD14+CD16- Monocytes, donor2)
• 11857-125A3
• 11858-125A4
• 11859-125A5
• 11860-125A6 (CD14+ monocytes - treated with BCG, donor1)
• 11861-125A7 (CD14+ monocytes - treated with IFN + N-hexane, donor1)
• 11862-125A8 (CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor1)
• 11863-125A9 (CD14+ monocytes - mock treated, donor1)
• 11864-125B1 (CD14+ monocytes - treated with Group A streptococci, donor1)

... further results

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002057 (CD14-positive, CD16-negative classical monocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

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P-value	FFCP	Short description

P-value	FFCP	Short description
2.95e-173	FFCP PHASE1:Hg19::chr7:44661060..44661101,-	p@chr7:44661060..44661101, -
2.95e-173	FFCP PHASE2:Hg19::chr7:44661060..44661101,-	p@chr7:44661060..44661101, -
5.66e-173	FFCP PHASE2:Hg19::chr17:72628050..72628077,-	p@chr17:72628050..72628077, -
5.66e-173	FFCP PHASE1:Hg19::chr17:72628050..72628077,-	p@chr17:72628050..72628077, -
3.48e-171	FFCP PHASE1:Hg19::chr17:72607002..72607029,+	p@chr17:72607002..72607029, +
3.48e-171	FFCP PHASE2:Hg19::chr17:72607002..72607029,+	p@chr17:72607002..72607029, +
2.61e-167	FFCP PHASE2:Hg19::chr17:72606825..72606838,-	p@chr17:72606825..72606838, -
2.61e-167	FFCP PHASE1:Hg19::chr17:72606825..72606838,-	p@chr17:72606825..72606838, -
1.41e-166	FFCP PHASE2:Hg19::chr17:72607152..72607174,-	p@chr17:72607152..72607174, -
1.41e-166	FFCP PHASE1:Hg19::chr17:72607152..72607174,-	p@chr17:72607152..72607174, -
1.31e-165	FFCP PHASE2:Hg19::chr17:72607351..72607373,-	p@chr17:72607351..72607373, -
1.31e-165	FFCP PHASE1:Hg19::chr17:72607351..72607373,-	p@chr17:72607351..72607373, -
8.2e-165	FFCP PHASE1:Hg19::chr1:120593738..120593745,+	p@chr1:120593738..120593745, +
8.2e-165	FFCP PHASE2:Hg19::chr1:120593738..120593745,+	p@chr1:120593738..120593745, +
1.7e-164	FFCP PHASE1:Hg19::chr14:55249943..55249971,+	p@chr14:55249943..55249971, +
1.7e-164	FFCP PHASE2:Hg19::chr14:55249943..55249971,+	p@chr14:55249943..55249971, +
6.24e-163	FFCP PHASE2:Hg19::chr8:11754835..11754867,-	p1@ENST00000525252
6.24e-163	FFCP PHASE1:Hg19::chr8:11754835..11754867,-	p1@ENST00000525252
2.9e-162	FFCP PHASE1:Hg19::chr12:125197870..125197907,+	p@chr12:125197870..125197907, +
2.9e-162	FFCP PHASE2:Hg19::chr12:125197870..125197907,+	p@chr12:125197870..125197907, +
2.93e-162	FFCP PHASE1:Hg19::chr17:72606678..72606702,-	p@chr17:72606678..72606702, -
2.93e-162	FFCP PHASE2:Hg19::chr17:72606678..72606702,-	p@chr17:72606678..72606702, -
3.23e-162	FFCP PHASE2:Hg19::chr22:17717917..17717939,-	p@chr22:17717917..17717939, -
3.23e-162	FFCP PHASE1:Hg19::chr22:17717917..17717939,-	p@chr22:17717917..17717939, -
4.13e-162	FFCP PHASE2:Hg19::chr5:156534439..156534470,+	p@chr5:156534439..156534470, +
4.13e-162	FFCP PHASE1:Hg19::chr5:156534439..156534470,+	p@chr5:156534439..156534470, +
1.23e-161	FFCP PHASE1:Hg19::chr9:137300477..137300490,+	p@chr9:137300477..137300490, +
1.23e-161	FFCP PHASE2:Hg19::chr9:137300477..137300490,+	p@chr9:137300477..137300490, +
6.16e-160	FFCP PHASE2:Hg19::chr1:149901972..149901989,-	p@chr1:149901972..149901989, -
6.16e-160	FFCP PHASE1:Hg19::chr1:149901972..149901989,-	p@chr1:149901972..149901989, -
3.22e-159	FFCP PHASE2:Hg19::chr2:145276939..145276960,+	p2@ZEB2-AS1
3.22e-159	FFCP PHASE1:Hg19::chr2:145276939..145276960,+	p2@ZEB2-AS1
4.01e-159	FFCP PHASE1:Hg19::chr11:68847955..68847972,-	p@chr11:68847955..68847972, -
4.01e-159	FFCP PHASE2:Hg19::chr11:68847955..68847972,-	p@chr11:68847955..68847972, -
1.14e-158	FFCP PHASE2:Hg19::chr11:68847043..68847057,+	p@chr11:68847043..68847057, +
1.14e-158	FFCP PHASE1:Hg19::chr11:68847043..68847057,+	p@chr11:68847043..68847057, +
5.8e-158	FFCP PHASE2:Hg19::chr1:108592890..108592921,-	p@chr1:108592890..108592921, -
5.8e-158	FFCP PHASE1:Hg19::chr1:108592890..108592921,-	p@chr1:108592890..108592921, -
2.44e-157	FFCP PHASE1:Hg19::chr7:949680..949694,-	p@chr7:949680..949694, -
2.44e-157	FFCP PHASE2:Hg19::chr7:949680..949694,-	p@chr7:949680..949694, -
4.86e-157	FFCP PHASE2:Hg19::chr7:48009999..48010016,+	p@chr7:48009999..48010016, +
4.86e-157	FFCP PHASE1:Hg19::chr7:48009999..48010016,+	p@chr7:48009999..48010016, +
5.49e-157	FFCP PHASE2:Hg19::chr4:185314351..185314392,+	p@chr4:185314351..185314392, +
5.49e-157	FFCP PHASE1:Hg19::chr4:185314351..185314392,+	p@chr4:185314351..185314392, +
8.29e-157	FFCP PHASE2:Hg19::chr16:82229835..82229848,+	p@chr16:82229835..82229848, +
8.29e-157	FFCP PHASE1:Hg19::chr16:82229835..82229848,+	p@chr16:82229835..82229848, +
2.1e-156	FFCP PHASE2:Hg19::chr20:5634031..5634046,+	p@chr20:5634031..5634046, +
2.1e-156	FFCP PHASE1:Hg19::chr20:5634031..5634046,+	p@chr20:5634031..5634046, +
4.29e-156	FFCP PHASE2:Hg19::chr4:159731607..159731627,+	p@chr4:159731607..159731627, +
4.29e-156	FFCP PHASE1:Hg19::chr4:159731607..159731627,+	p@chr4:159731607..159731627, +
1.66e-155	FFCP PHASE1:Hg19::chr9:102353301..102353315,-	p@chr9:102353301..102353315, -
1.66e-155	FFCP PHASE2:Hg19::chr9:102353301..102353315,-	p@chr9:102353301..102353315, -
3.6e-155	FFCP PHASE1:Hg19::chr2:145450907..145450928,-	p@chr2:145450907..145450928, -
3.6e-155	FFCP PHASE2:Hg19::chr2:145450907..145450928,-	p@chr2:145450907..145450928, -
3.76e-155	FFCP PHASE2:Hg19::chr17:72628206..72628246,+	p@chr17:72628206..72628246, +
3.76e-155	FFCP PHASE1:Hg19::chr17:72628206..72628246,+	p@chr17:72628206..72628246, +
1.6e-154	FFCP PHASE2:Hg19::chr8:11755021..11755054,+	p@chr8:11755021..11755054, +
1.6e-154	FFCP PHASE1:Hg19::chr8:11755021..11755054,+	p@chr8:11755021..11755054, +
1.99e-154	FFCP PHASE2:Hg19::chr2:145421047..145421067,+	p@chr2:145421047..145421067, +
1.99e-154	FFCP PHASE1:Hg19::chr2:145421047..145421067,+	p@chr2:145421047..145421067, +
4.18e-154	FFCP PHASE2:Hg19::chr6:106348152..106348164,+	p@chr6:106348152..106348164, +
4.18e-154	FFCP PHASE1:Hg19::chr6:106348152..106348164,+	p@chr6:106348152..106348164, +
9.99e-154	FFCP PHASE1:Hg19::chr16:17469894..17469904,+	p@chr16:17469894..17469904, +
9.99e-154	FFCP PHASE2:Hg19::chr16:17469894..17469904,+	p@chr16:17469894..17469904, +
1.29e-153	FFCP PHASE1:Hg19::chr1:40006573..40006589,-	p@chr1:40006573..40006589, -
1.29e-153	FFCP PHASE2:Hg19::chr1:40006573..40006589,-	p@chr1:40006573..40006589, -
1.38e-153	FFCP PHASE1:Hg19::chr7:111720716..111720750,+	p@chr7:111720716..111720750, +
1.38e-153	FFCP PHASE2:Hg19::chr7:111720716..111720750,+	p@chr7:111720716..111720750, +
1.95e-153	FFCP PHASE2:Hg19::chr3:128943968..128943986,+	p@chr3:128943968..128943986, +
1.95e-153	FFCP PHASE1:Hg19::chr3:128943968..128943986,+	p@chr3:128943968..128943986, +
3.44e-153	FFCP PHASE2:Hg19::chr2:58339774..58339779,-	p@chr2:58339774..58339779, -
3.44e-153	FFCP PHASE1:Hg19::chr2:58339774..58339779,-	p@chr2:58339774..58339779, -
4.04e-153	FFCP PHASE1:Hg19::chr11:61737685..61737701,-	p@chr11:61737685..61737701, -
4.04e-153	FFCP PHASE2:Hg19::chr11:61737685..61737701,-	p@chr11:61737685..61737701, -
5.57e-153	FFCP PHASE1:Hg19::chr11:10921401..10921434,-	p@chr11:10921401..10921434, -
5.57e-153	FFCP PHASE2:Hg19::chr11:10921401..10921434,-	p@chr11:10921401..10921434, -
2.07e-152	FFCP PHASE1:Hg19::chr1:212659324..212659370,-	p@chr1:212659324..212659370, -
2.07e-152	FFCP PHASE2:Hg19::chr1:212659324..212659370,-	p@chr1:212659324..212659370, -
2.23e-152	FFCP PHASE1:Hg19::chr19:4812881..4812891,-	p@chr19:4812881..4812891, -
2.23e-152	FFCP PHASE2:Hg19::chr19:4812881..4812891,-	p@chr19:4812881..4812891, -
3.99e-152	FFCP PHASE1:Hg19::chr18:13577406..13577430,-	p@chr18:13577406..13577430, -
3.99e-152	FFCP PHASE2:Hg19::chr18:13577406..13577430,-	p@chr18:13577406..13577430, -
4.17e-152	FFCP PHASE1:Hg19::chr9:137264021..137264038,+	p@chr9:137264021..137264038, +
4.17e-152	FFCP PHASE2:Hg19::chr9:137264021..137264038,+	p@chr9:137264021..137264038, +
4.44e-152	FFCP PHASE2:Hg19::chr8:48173159..48173173,+	p6@KIAA0146
4.44e-152	FFCP PHASE1:Hg19::chr8:48173159..48173173,+	p6@KIAA0146
6.49e-152	FFCP PHASE2:Hg19::chr8:71452856..71452863,+	p@chr8:71452856..71452863, +
6.49e-152	FFCP PHASE1:Hg19::chr8:71452856..71452863,+	p@chr8:71452856..71452863, +
6.68e-152	FFCP PHASE1:Hg19::chr22:28065655..28065677,+	p@chr22:28065655..28065677, +
6.68e-152	FFCP PHASE2:Hg19::chr22:28065655..28065677,+	p@chr22:28065655..28065677, +
1.17e-151	FFCP PHASE1:Hg19::chr20:5626328..5626343,+	p@chr20:5626328..5626343, +
1.17e-151	FFCP PHASE2:Hg19::chr20:5626328..5626343,+	p@chr20:5626328..5626343, +
2.27e-151	FFCP PHASE1:Hg19::chr7:151622937..151622965,-	p@chr7:151622937..151622965, -
2.27e-151	FFCP PHASE2:Hg19::chr7:151622937..151622965,-	p@chr7:151622937..151622965, -
6.5e-151	FFCP PHASE1:Hg19::chr17:72635873..72635891,-	p@chr17:72635873..72635891, -
6.5e-151	FFCP PHASE2:Hg19::chr17:72635873..72635891,-	p@chr17:72635873..72635891, -
1.04e-150	FFCP PHASE1:Hg19::chr17:72636264..72636304,+	p@chr17:72636264..72636304, +
1.04e-150	FFCP PHASE2:Hg19::chr17:72636264..72636304,+	p@chr17:72636264..72636304, +
1.28e-150	FFCP PHASE1:Hg19::chr7:2814742..2814772,+	p@chr7:2814742..2814772, +
1.28e-150	FFCP PHASE2:Hg19::chr7:2814742..2814772,+	p@chr7:2814742..2814772, +

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