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DOID:3571

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Name:liver cancer
Namespace:FANTOM
Definition:"A gastrointestinal system cancer that is located_in the liver." [url:http://en.wikipedia.org/wiki/Liver]
Xrefs:
links:

MSH:D008113
SNOMEDCT_2010_1_31:126851005
SNOMEDCT_2010_1_31:154470007
SNOMEDCT_2010_1_31:187768001
SNOMEDCT_2010_1_31:187771009
SNOMEDCT_2010_1_31:187779006
SNOMEDCT_2010_1_31:269548006
SNOMEDCT_2010_1_31:363361004
SNOMEDCT_2010_1_31:93870000
SNOMEDCT_2010_1_31:95214007
UMLS_CUI:C0023903
UMLS_CUI:C0024620
UMLS_CUI:C0345904
UMLS_CUI:C0854795
UMLS_CUI:C0861869

UMLS_CUI:C1334590
Synonyms: "ca liver - primary" EXACT []
"Ca liver - primary (disorder)" EXACT [SNOMEDCT_2005_07_31:269548006]
"hepatic cancer" EXACT [CSP2005:2003-2810]
"hepatic neoplasm" EXACT [CSP2005:2003-2810]
"malignant hepato-biliary neoplasm" EXACT []
"malignant neoplasm of liver" EXACT []
"malignant neoplasm of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:93870000]
"malignant neoplasm of liver unspecified (disorder)" EXACT [SNOMEDCT_2005_07_31:187779006]
"malignant neoplasm of liver, not specified as primary or secondary" EXACT [ICD9CM_2006:155.2]
"malignant neoplasm of liver, primary" EXACT [ICD9CM_2006:155.0]
"malignant tumor of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:363361004]
"neoplasm of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:126851005]
"non-resectable primary hepatic malignant neoplasm" EXACT []
"primary liver cancer" EXACT []
"primary malignant neoplasm of Liver" EXACT [NCI2004_11_17:C34803]
"primary malignant neoplasm of liver" EXACT [SNOMEDCT_2005_07_31:187768001, SNOMEDCT_2005_07_31:93870000]
"primary malignant neoplasm of liver (disorder)" EXACT [SNOMEDCT_2005_07_31:95214007]
"primary malignant neoplasm of liver NOS (disorder)" EXACT [SNOMEDCT_2005_07_31:187771009]
"Resectable malignant neoplasm of Liver" EXACT [NCI2004_11_17:C7692]
"resectable malignant neoplasm of the liver" EXACT []
Alt_id: DOID:12300
DOID:269
DOID:7330
DOID:915
DOID:919

Ontology association<br>Each term has an is_a parent in the Disease Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to DISEASE ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:DOID:3119(gastrointestinal system cancer)



Children


is a:FF:10778-110G4 (hepatic mesenchymal tumor cell line:LI90),DOID:686 (liver carcinoma),DOID:687 (hepatoblastoma)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples

Human (Homo sapiens)

Mouse (Mus musculus)

Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with DOID:3571 (liver cancer), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
2.55e-98FFCP PHASE1:Hg19::chr13:38275506..38275512,-#_f9cf370e5b66b6df35a92cf7b226209fp@chr13:38275506..38275512, -
2.55e-98FFCP PHASE2:Hg19::chr13:38275506..38275512,-#_f9cf370e5b66b6df35a92cf7b226209fp@chr13:38275506..38275512, -
6.58e-50FFCP PHASE1:Hg19::chr19:10402114..10402120,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp6@ICAM5
6.58e-50FFCP PHASE1:Hg19::chr21:47424477..47424486,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp@chr21:47424477..47424486, +
6.58e-50FFCP PHASE2:Hg19::chr19:10402114..10402120,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp6@ICAM5
6.58e-50FFCP PHASE2:Hg19::chr21:47424477..47424486,+#_f5cb02c3ba8c4626f2963bb22eb9e84bp@chr21:47424477..47424486, +
6.62e-41FFCP PHASE1:Hg19::chr2:217538399..217538408,-#_c01de8a807c4ffbc3e2641576222d893p75@IGFBP5
6.62e-41FFCP PHASE2:Hg19::chr2:217538399..217538408,-#_c01de8a807c4ffbc3e2641576222d893p75@IGFBP5
1.48e-40FFCP PHASE1:Hg19::chr12:109094948..109094959,-#_21d9a7dcb034f7492532e32076809206p31@CORO1C
1.48e-40FFCP PHASE2:Hg19::chr12:109094948..109094959,-#_21d9a7dcb034f7492532e32076809206p31@CORO1C
1.48e-40FFCP PHASE1:Hg19::chr6:169588737..169588744,-#_21d9a7dcb034f7492532e32076809206p@chr6:169588737..169588744, -
1.48e-40FFCP PHASE2:Hg19::chr6:169588737..169588744,-#_21d9a7dcb034f7492532e32076809206p@chr6:169588737..169588744, -
2.21e-40FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_a078ebefb0726ab60932fa0f414ec53ep@chr2:133426030..133426041, -
2.21e-40FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_a078ebefb0726ab60932fa0f414ec53ep@chr2:133426030..133426041, -
2.21e-40FFCP PHASE1:Hg19::chr14:80090211..80090214,+#_a078ebefb0726ab60932fa0f414ec53ep@chr14:80090211..80090214, +
2.21e-40FFCP PHASE2:Hg19::chr14:80090211..80090214,+#_a078ebefb0726ab60932fa0f414ec53ep@chr14:80090211..80090214, +
3.61e-34FFCP PHASE1:Hg19::chr5:167396347..167396349,+#_ba6072bc176bf364cabb22cec8c29d77p@chr5:167396347..167396349, +
3.61e-34FFCP PHASE2:Hg19::chr5:167396347..167396349,+#_ba6072bc176bf364cabb22cec8c29d77p@chr5:167396347..167396349, +
7.48e-30FFCP PHASE1:Hg19::chr7:41729165..41729178,-#_20c620d88660dbcb5a71c8b4d6c3b94ap@chr7:41729165..41729178, -
7.48e-30FFCP PHASE2:Hg19::chr7:41729165..41729178,-#_20c620d88660dbcb5a71c8b4d6c3b94ap@chr7:41729165..41729178, -
1.78e-29FFCP PHASE2:Hg19::chr2:217536930..217536944,-#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chr2:217536930..217536944, -
1.78e-29FFCP PHASE1:Hg19::chrX:149716271..149716273,+#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chrX:149716271..149716273, +
1.78e-29FFCP PHASE2:Hg19::chrX:149716271..149716273,+#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chrX:149716271..149716273, +
1.78e-29FFCP PHASE1:Hg19::chr2:217536930..217536944,-#_8fd6b2e34da8e9b7c5a2a373c3bc0530p@chr2:217536930..217536944, -
2.37e-29FFCP PHASE2:Hg19::chr16:71123774..71123782,+#_753c59b6635236623b52b06aba6fabefp@chr16:71123774..71123782, +
2.37e-29FFCP PHASE1:Hg19::chr16:71123774..71123782,+#_753c59b6635236623b52b06aba6fabefp@chr16:71123774..71123782, +
3.16e-29FFCP PHASE1:Hg19::chr9:21505583..21505593,-#_90bc52b0789efc2d3b6d93d6efbd1584p@chr9:21505583..21505593, -
3.16e-29FFCP PHASE2:Hg19::chr9:21505583..21505593,-#_90bc52b0789efc2d3b6d93d6efbd1584p@chr9:21505583..21505593, -
3.16e-29FFCP PHASE1:Hg19::chr7:136553339..136553348,+#_90bc52b0789efc2d3b6d93d6efbd1584p11@CHRM2
3.16e-29FFCP PHASE2:Hg19::chr7:136553339..136553348,+#_90bc52b0789efc2d3b6d93d6efbd1584p11@CHRM2
4.61e-26FFCP PHASE1:Hg19::chr15:33018927..33018930,+#_3792ab777780d2e9e137e1d5a97fc7b5p@chr15:33018927..33018930, +
4.61e-26FFCP PHASE1:Hg19::chr3:141103437..141103451,+#_3792ab777780d2e9e137e1d5a97fc7b5p55@ZBTB38
4.61e-26FFCP PHASE2:Hg19::chr3:141103437..141103451,+#_3792ab777780d2e9e137e1d5a97fc7b5p55@ZBTB38
4.61e-26FFCP PHASE2:Hg19::chr15:33018927..33018930,+#_3792ab777780d2e9e137e1d5a97fc7b5p@chr15:33018927..33018930, +
5.93e-26FFCP PHASE1:Hg19::chr1:172972632..172972638,+#_2e8f1c570467ac49add6287ab4e8e3cdp@chr1:172972632..172972638, +
5.93e-26FFCP PHASE2:Hg19::chr1:172972632..172972638,+#_2e8f1c570467ac49add6287ab4e8e3cdp@chr1:172972632..172972638, +
7.62e-26FFCP PHASE1:Hg19::chr4:95508126..95508142,+#_0182757e036dd40fd731f7476662dc7cp@chr4:95508126..95508142, +
7.62e-26FFCP PHASE2:Hg19::chr4:95508126..95508142,+#_0182757e036dd40fd731f7476662dc7cp@chr4:95508126..95508142, +
9.79e-26FFCP PHASE1:Hg19::chr12:12272276..12272282,-#_7a080033518eb44593b6b3160a93d722p@chr12:12272276..12272282, -
9.79e-26FFCP PHASE2:Hg19::chr12:12272276..12272282,-#_7a080033518eb44593b6b3160a93d722p@chr12:12272276..12272282, -
9.79e-26FFCP PHASE1:Hg19::chr21:38071760..38071776,+#_7a080033518eb44593b6b3160a93d722p5@SIM2
9.79e-26FFCP PHASE2:Hg19::chr21:38071760..38071776,+#_7a080033518eb44593b6b3160a93d722p5@SIM2
1.26e-25FFCP PHASE1:Hg19::chr15:39486488..39486494,-#_45c36a51c37d8b778d6c2bfd66d34bacp6@ENST00000560743
1.26e-25FFCP PHASE2:Hg19::chr15:39486488..39486494,-#_45c36a51c37d8b778d6c2bfd66d34bacp6@ENST00000560743
2.1e-23FFCP PHASE1:Hg19::chr9:119164000..119164021,+#_063a9fb19019c2b5672ccc0b7cd9ca8ap@chr9:119164000..119164021, +
2.1e-23FFCP PHASE2:Hg19::chr9:119164000..119164021,+#_063a9fb19019c2b5672ccc0b7cd9ca8ap@chr9:119164000..119164021, +
5.13e-23FFCP PHASE2:Hg19::chr13:76258701..76258705,+#_ce5ecf06379aba35d606fbb0047c4360p@chr13:76258701..76258705, +
5.13e-23FFCP PHASE1:Hg19::chr6:52272474..52272475,-#_ce5ecf06379aba35d606fbb0047c4360p@chr6:52272474..52272475, -
5.13e-23FFCP PHASE1:Hg19::chr2:27858182..27858185,+#_ce5ecf06379aba35d606fbb0047c4360p@chr2:27858182..27858185, +
5.13e-23FFCP PHASE2:Hg19::chr6:52272474..52272475,-#_ce5ecf06379aba35d606fbb0047c4360p@chr6:52272474..52272475, -
5.13e-23FFCP PHASE2:Hg19::chr2:27858182..27858185,+#_ce5ecf06379aba35d606fbb0047c4360p@chr2:27858182..27858185, +
5.13e-23FFCP PHASE1:Hg19::chr13:76258701..76258705,+#_ce5ecf06379aba35d606fbb0047c4360p@chr13:76258701..76258705, +
6.4e-23FFCP PHASE1:Hg19::chr5:14156841..14156863,+#_47390fd13fb35497b43c44b67f3faca9p@chr5:14156841..14156863, +
6.4e-23FFCP PHASE2:Hg19::chr5:14156841..14156863,+#_47390fd13fb35497b43c44b67f3faca9p@chr5:14156841..14156863, +
5.16e-21FFCP PHASE1:Hg19::chr6:132269901..132269911,-#_24d29aec9891b95c833f8615a4d2ee48p30@CTGF
5.16e-21FFCP PHASE2:Hg19::chr6:132269901..132269911,-#_24d29aec9891b95c833f8615a4d2ee48p30@CTGF
6.31e-21FFCP PHASE1:Hg19::chr10:97262828..97262865,-#_a79271896553fc41bf727d7cfcfac869p@chr10:97262828..97262865, -
6.31e-21FFCP PHASE2:Hg19::chr10:97262828..97262865,-#_a79271896553fc41bf727d7cfcfac869p@chr10:97262828..97262865, -
1.3e-19FFCP PHASE1:Hg19::chr14:55034385..55034400,+#_f83e245872cb40fb62b3878c1a4665cap20@SAMD4A
1.3e-19FFCP PHASE2:Hg19::chr14:55034385..55034400,+#_f83e245872cb40fb62b3878c1a4665cap20@SAMD4A
2.25e-19FFCP PHASE1:Hg19::chr2:134432699..134432711,-#_a38494a90217e9d624f638ca288d54b6p@chr2:134432699..134432711, -
2.25e-19FFCP PHASE2:Hg19::chr2:134432699..134432711,-#_a38494a90217e9d624f638ca288d54b6p@chr2:134432699..134432711, -
3.25e-19FFCP PHASE1:Hg19::chr3:100539939..100539944,-#_9b0ef131f0e90d1e342a7150bb7676a6p@chr3:100539939..100539944, -
3.25e-19FFCP PHASE2:Hg19::chr3:100539939..100539944,-#_9b0ef131f0e90d1e342a7150bb7676a6p@chr3:100539939..100539944, -
3.91e-19FFCP PHASE1:Hg19::chr1:152412443..152412445,+#_9cb4a2abafd92907f92422ca0f878c59p@chr1:152412443..152412445, +
3.91e-19FFCP PHASE2:Hg19::chr1:152412443..152412445,+#_9cb4a2abafd92907f92422ca0f878c59p@chr1:152412443..152412445, +
4.69e-19FFCP PHASE1:Hg19::chr12:104645296..104645338,+#_b618505f946f2ce636a76e8d232f6db4p11@TXNRD1
4.69e-19FFCP PHASE2:Hg19::chr12:104645296..104645338,+#_b618505f946f2ce636a76e8d232f6db4p11@TXNRD1
5.62e-19FFCP PHASE2:Hg19::chr12:96199635..96199641,-#_4d3380ab633a8be6e23c89173408ba56p@chr12:96199635..96199641, -
5.62e-19FFCP PHASE1:Hg19::chr12:96199635..96199641,-#_4d3380ab633a8be6e23c89173408ba56p@chr12:96199635..96199641, -
3.16e-18FFCP PHASE1:Hg19::chr7:41729687..41729699,-#_1405ee799e1c1d4227338e74317ffc44p15@INHBA
3.16e-18FFCP PHASE2:Hg19::chr7:41729687..41729699,-#_1405ee799e1c1d4227338e74317ffc44p15@INHBA
3.75e-18FFCP PHASE2:Hg19::chr15:68655572..68655579,-#_b6eff708e5537003835de7bdf9975f56p@chr15:68655572..68655579, -
3.75e-18FFCP PHASE1:Hg19::chr15:68655572..68655579,-#_b6eff708e5537003835de7bdf9975f56p@chr15:68655572..68655579, -
4.44e-18FFCP PHASE1:Hg19::chr5:14145555..14145567,-#_d78cbeeea86b5d75b7faa7ba94f32ac1p@chr5:14145555..14145567, -
4.44e-18FFCP PHASE2:Hg19::chr5:14145555..14145567,-#_d78cbeeea86b5d75b7faa7ba94f32ac1p@chr5:14145555..14145567, -
5.26e-18FFCP PHASE1:Hg19::chr9:119164050..119164076,+#_c1a22b1bd3b81efd7402cd3a549e24bep@chr9:119164050..119164076, +
5.26e-18FFCP PHASE2:Hg19::chr9:119164050..119164076,+#_c1a22b1bd3b81efd7402cd3a549e24bep@chr9:119164050..119164076, +
6.23e-18FFCP PHASE1:Hg19::chr11:27723059..27723067,-#_4e1ffc6496dc5141cdd8b9a76b5730aep11@BDNF
6.23e-18FFCP PHASE2:Hg19::chr11:27723059..27723067,-#_4e1ffc6496dc5141cdd8b9a76b5730aep11@BDNF
7.37e-18FFCP PHASE1:Hg19::chr8:106489489..106489493,+#_19349b1137cfcc0bffcfd3ae3a955238p@chr8:106489489..106489493, +
7.37e-18FFCP PHASE2:Hg19::chr8:106489489..106489493,+#_19349b1137cfcc0bffcfd3ae3a955238p@chr8:106489489..106489493, +
8.72e-18FFCP PHASE1:Hg19::chr2:134325832..134325855,-#_77c950f5c7185aa98e9b96c7e777b14cp7@NCKAP5
8.72e-18FFCP PHASE2:Hg19::chr2:134325832..134325855,-#_77c950f5c7185aa98e9b96c7e777b14cp7@NCKAP5
1.03e-17FFCP PHASE1:Hg19::chr13:38145589..38145600,-#_9f1d254dba5c23bca49a6b46f6b9a7b9p12@POSTN
1.03e-17FFCP PHASE2:Hg19::chr13:38145589..38145600,-#_9f1d254dba5c23bca49a6b46f6b9a7b9p12@POSTN
1.22e-17FFCP PHASE1:Hg19::chr3:159943174..159943185,+#_73bfe40815a75ef63ab7a028bb376064p7@C3orf80
1.22e-17FFCP PHASE2:Hg19::chr3:159943174..159943185,+#_73bfe40815a75ef63ab7a028bb376064p7@C3orf80
1.22e-17FFCP PHASE1:Hg19::chr6:150185105..150185119,-#_73bfe40815a75ef63ab7a028bb376064p5@LRP11
1.22e-17FFCP PHASE2:Hg19::chr6:150185105..150185119,-#_73bfe40815a75ef63ab7a028bb376064p5@LRP11
1.22e-17FFCP PHASE1:Hg19::chr9:119131199..119131210,+#_73bfe40815a75ef63ab7a028bb376064p@chr9:119131199..119131210, +
1.22e-17FFCP PHASE2:Hg19::chr9:119131199..119131210,+#_73bfe40815a75ef63ab7a028bb376064p@chr9:119131199..119131210, +
1.7e-17FFCP PHASE1:Hg19::chr3:193855009..193855029,+#_520e1cba074acb6e900f2b144a46c495p@chr3:193855009..193855029, +
1.7e-17FFCP PHASE2:Hg19::chr3:193855009..193855029,+#_520e1cba074acb6e900f2b144a46c495p@chr3:193855009..193855029, +
4.72e-17FFCP PHASE1:Hg19::chr2:217537210..217537213,-#_f3e0e250b19b5bb7cf8324d00de28b7cp54@IGFBP5
4.72e-17FFCP PHASE2:Hg19::chr2:217537210..217537213,-#_f3e0e250b19b5bb7cf8324d00de28b7cp54@IGFBP5
5.53e-17FFCP PHASE1:Hg19::chr12:47497443..47497474,+#_cac71162391ba537b411e15822756e3ap@chr12:47497443..47497474, +
5.53e-17FFCP PHASE2:Hg19::chr12:47497443..47497474,+#_cac71162391ba537b411e15822756e3ap@chr12:47497443..47497474, +
6.47e-17FFCP PHASE1:Hg19::chr4:7844024..7844029,-#_c1f4f6dcabf876202b644440e96bf18ap@chr4:7844024..7844029, -
6.47e-17FFCP PHASE2:Hg19::chr4:7844024..7844029,-#_c1f4f6dcabf876202b644440e96bf18ap@chr4:7844024..7844029, -

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