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MCL coexpression mm9:442

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:61392754..61392766,-p@chr11:61392754..61392766
-
Mm9::chr15:99230200..99230234,+p@chr15:99230200..99230234
+
Mm9::chr16:95500961..95500974,+p9@Kcnj15
Mm9::chr17:28654436..28654449,-p6@Fkbp5
Mm9::chr17:28654454..28654503,-p2@Fkbp5
Mm9::chr19:20567067..20567078,+p6@E030003E18Rik
Mm9::chr19:20567096..20567107,+p3@E030003E18Rik
Mm9::chr19:20567153..20567160,+p7@E030003E18Rik
Mm9::chr19:20567168..20567179,+p5@E030003E18Rik
Mm9::chr1:43198700..43198717,-p@chr1:43198700..43198717
-
Mm9::chr1:74044459..74044466,-p@chr1:74044459..74044466
-
Mm9::chr1:78813484..78813488,+p1@Kcne4
Mm9::chr2:25256065..25256077,+p3@Npdc1
Mm9::chr6:91222464..91222477,+p@chr6:91222464..91222477
+
Mm9::chr8:11449034..11449045,+p@chr8:11449034..11449045
+
Mm9::chr9:102766842..102766853,+p@chr9:102766842..102766853
+
Mm9::chr9:21574473..21574490,-p@chr9:21574473..21574490
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005249voltage-gated potassium channel activity0.0122444119045219
GO:0030955potassium ion binding0.0122444119045219
GO:0022843voltage-gated cation channel activity0.0122444119045219
GO:0005267potassium channel activity0.0122444119045219
GO:0006813potassium ion transport0.0128416386282628
GO:0022832voltage-gated channel activity0.0128416386282628
GO:0005244voltage-gated ion channel activity0.0128416386282628
GO:0031420alkali metal ion binding0.0128416386282628
GO:0016505apoptotic protease activator activity0.0190961456510468
GO:0005261cation channel activity0.0190961456510468
GO:0022836gated channel activity0.0198529700108855
GO:0046873metal ion transmembrane transporter activity0.0204301555929285
GO:0015672monovalent inorganic cation transport0.0204301555929285
GO:0016504protease activator activity0.0223896866406807
GO:0005216ion channel activity0.0223896866406807
GO:0022838substrate specific channel activity0.0223896866406807
GO:0005242inward rectifier potassium channel activity0.0223896866406807
GO:0030693caspase activity0.0223896866406807
GO:0022803passive transmembrane transporter activity0.0223896866406807
GO:0015267channel activity0.0223896866406807
GO:0030001metal ion transport0.0231536167857767
GO:0008324cation transmembrane transporter activity0.029217087446526
GO:0006812cation transport0.029217087446526
GO:0043281regulation of caspase activity0.0394981256273736
GO:0003755peptidyl-prolyl cis-trans isomerase activity0.0411462600089206
GO:0016859cis-trans isomerase activity0.0411462600089206
GO:0015075ion transmembrane transporter activity0.0446302359362335



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
muscle precursor cell7.78e-076
contractile cell7.78e-076
muscle cell7.78e-076
myoblast7.78e-076

Uber Anatomy
Ontology termp-valuen
cardiovascular system1.76e-0823
circulatory system1.76e-0823
primary circulatory organ5.05e-0718
heart5.05e-0718
primitive heart tube5.05e-0718
primary heart field5.05e-0718
anterior lateral plate mesoderm5.05e-0718
heart tube5.05e-0718
heart primordium5.05e-0718
cardiac mesoderm5.05e-0718
cardiogenic plate5.05e-0718
heart rudiment5.05e-0718


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0397665
MA0004.10.594255
MA0006.10.0950487
MA0007.11.07904
MA0009.13.53326
MA0014.10.203425
MA0017.10.722188
MA0019.10.413421
MA0024.10.536784
MA0025.10.795679
MA0027.12.19092
MA0028.10.100975
MA0029.10.51708
MA0030.10.523021
MA0031.10.490954
MA0038.10.319246
MA0040.10.588314
MA0041.10.152751
MA0042.10.144042
MA0043.10.666547
MA0046.10.609938
MA0048.10.619737
MA0050.10.662757
MA0051.10.326637
MA0052.10.595747
MA0055.10.623372
MA0056.10
MA0057.10.336486
MA0058.10.431697
MA0059.10.147666
MA0060.10.0544856
MA0061.10.241633
MA0063.10
MA0066.10.310219
MA0067.10.902253
MA0068.10.58378
MA0069.10.59606
MA0070.10.587119
MA0071.10.234437
MA0072.10.579318
MA0073.16.24648e-05
MA0074.10.769072
MA0076.10.122031
MA0077.10.559443
MA0078.10.354249
MA0081.10.163204
MA0083.10.665805
MA0084.11.22195
MA0087.10.625609
MA0088.10.00645469
MA0089.10
MA0090.11.62103
MA0091.11.15975
MA0092.10.535473
MA0093.10.344191
MA0095.10
MA0098.10
MA0100.10.748039
MA0101.10.153616
MA0103.10.373479
MA0105.10.269753
MA0106.10.360817
MA0107.10.363753
MA0108.20.433384
MA0109.10
MA0111.11.06448
MA0113.14.34612
MA0114.10.0673452
MA0115.11.60586
MA0116.10.650012
MA0117.10.639033
MA0119.11.46173
MA0122.10.657549
MA0124.10.851049
MA0125.10.780232
MA0130.10
MA0131.11.05433
MA0132.10
MA0133.10
MA0135.10.700734
MA0136.10.297196
MA0139.10.160584
MA0140.10.271883
MA0141.10.129134
MA0142.10.477975
MA0143.10.350815
MA0144.10.890316
MA0145.10.654323
MA0146.10.0854498
MA0147.10.260161
MA0148.10.218033
MA0149.10.157322
MA0062.20.0281188
MA0035.20.275617
MA0039.20.13763
MA0138.20.402586
MA0002.20.0425713
MA0137.20.400341
MA0104.20.0483916
MA0047.20.318614
MA0112.21.26961
MA0065.20.115152
MA0150.10.195003
MA0151.10
MA0152.10.318703
MA0153.10.716409
MA0154.11.26673
MA0155.11.40943
MA0156.10.121496
MA0157.10.4495
MA0158.10
MA0159.10.0802352
MA0160.10.220282
MA0161.10
MA0162.10.000667848
MA0163.10.000516301
MA0164.10.806095
MA0080.20.113741
MA0018.20.305372
MA0099.21.81477
MA0079.20.00168885
MA0102.21.27355
MA0258.10.478272
MA0259.10.0696308
MA0442.10