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UBERON:0001235

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Name:adrenal cortex
Namespace:FANTOM
Definition:"Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, including aldosterone and cortisol respectively. It is also a secondary site of androgen synthesis. [WP,unvetted]." [Wikipedia:Adrenal_cortex]
Xrefs:
links:

AAO:0011009
BTO:0000045
EFO:0000237
EMAPA:18427
EV:0100136
FMA:15632
GAID:447
[ Gray1185.png Gray1185.png]
[ 200px-Gray1185.png 200px-Gray1185.png]
MA:0000118
MAT:0000494
MESH:A.06.407.071.140
ncithesaurus:Adrenal_Cortex
SCTID:362584002
VHOG:0001481

XAO:0000165
Synonyms: "adrenal gland cortex" EXACT []
"cortex (glandula suprarenalis)" EXACT []
"cortex glandulae suprarenalis" RELATED LATIN [Wikipedia:Adrenal_cortex]
"cortex glandulae suprarenalis" RELATED [BTO:0000045]
"cortex of adrenal gland" EXACT []
"cortex of suprarenal gland" EXACT []
"suprarenal" RELATED []
"suprarenal cortex" EXACT []
Comments:Taxon notes: Kardong states that mammals are the first to have distinct cortext and medulla, but this contradicts XAO
Alt_id: UBERON:FMA_15632-MA_0000118-XAO_0000165
Subset: uberon_slim

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0001851(cortex),UBERON:0004120(mesoderm-derived structure)
develops_from:UBERON:0000926(mesoderm)
part_of:UBERON:0002369(adrenal gland)



Children

is a:FF:10810-111A9 (adrenal cortex adenocarcinoma cell line:SW-13)
part of:CL:0002097 (cortical cell of adrenal gland)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0001235 (adrenal cortex), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data