UBERON:0002242
From FANTOM5_SSTAR
| Name: | nucleus pulposus | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "a jelly-like connective tissue in the middle of the spinal disc. It is the remnant of the notochord. It functions to distribute hydraulic pressure in all directions within each disc under compressive loads. The nucleus pulposus consists of chondrocytes, collagen fibrils, and proteoglycan aggrecans that have hyaluronic long chains which attract water. Attached to each hyaluronic chain are side chains of chondroitin sulfate and keratan sulfate[WP]." [Wikipedia:Nucleus_pulposus] | ||
| Xrefs: |
| ||
| Synonyms: |
"nucleus propulsus" RELATED [Wikipedia:Nucleus_pulposus] "nucleus propulsus of intervertebral disk" RELATED [Wikipedia:Nucleus_pulposus] "pulpy nucleus" EXACT [] | ||
| Alt_id: | UBERON:FMA_76703-MA_0000112 | ||
| Subset: | uberon_slim |
Cervical_vertebra_english.png]
200px-Cervical_vertebra_english.png]
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0002384(connective tissue),UBERON:0004120(mesoderm-derived structure),UBERON:0004121(ectoderm-derived structure) |
|---|---|
| develops_from: | UBERON:0002328(notochord) |
| part_of: | UBERON:0001066(intervertebral disk) |
Children
| part of: | CL:0002564 (nucleus pulposus cell of intervertebral disc) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 11252-116F1 (Nucleus Pulposus Cell, donor1)
- 11409-118E5 (Nucleus Pulposus Cell, donor2)
- 11462-119B4 (Nucleus Pulposus Cell, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002242 (nucleus pulposus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 8.26e-98 | FFCP PHASE2:Hg19::chr3:174737010..174737023,+#_9908bbdfe64e7253070e2d1b5d5e68b3 | p@chr3:174737010..174737023, + |
| 8.26e-98 | FFCP PHASE1:Hg19::chr3:174737010..174737023,+#_9908bbdfe64e7253070e2d1b5d5e68b3 | p@chr3:174737010..174737023, + |
| 3.03e-84 | FFCP PHASE2:Hg19::chr20:21687193..21687206,+#_b283cc778965e26d8136ca1087fdb7f4 | p4@PAX1 |
| 3.03e-84 | FFCP PHASE1:Hg19::chr20:21687193..21687206,+#_b283cc778965e26d8136ca1087fdb7f4 | p4@PAX1 |
| 2.39e-66 | FFCP PHASE2:Hg19::chr9:33028063..33028067,-#_ac2a9f31d3fac17daa397a110618c700 | p@chr9:33028063..33028067, - |
| 2.39e-66 | FFCP PHASE1:Hg19::chr9:33028063..33028067,-#_ac2a9f31d3fac17daa397a110618c700 | p@chr9:33028063..33028067, - |
| 5.46e-60 | FFCP PHASE1:Hg19::chr5:30104176..30104187,-#_d91c248ea1fd2f92d4e0878a0077a876 | p@chr5:30104176..30104187, - |
| 5.46e-60 | FFCP PHASE2:Hg19::chr5:30104176..30104187,-#_d91c248ea1fd2f92d4e0878a0077a876 | p@chr5:30104176..30104187, - |
| 9.77e-45 | FFCP PHASE1:Hg19::chr2:241987807..241987808,+#_3e91449f47dd7e4ca724a9ad67ef7905 | p22@SNED1 |
| 9.77e-45 | FFCP PHASE2:Hg19::chr2:241987807..241987808,+#_3e91449f47dd7e4ca724a9ad67ef7905 | p22@SNED1 |
| 6.64e-41 | FFCP PHASE1:Hg19::chr2:242004292..242004308,+#_7797fd4f89d58dbd362680306fc43476 | p15@SNED1 |
| 6.64e-41 | FFCP PHASE2:Hg19::chr2:242004292..242004308,+#_7797fd4f89d58dbd362680306fc43476 | p15@SNED1 |
| 1.31e-40 | FFCP PHASE2:Hg19::chr1:19811132..19811155,-#_2da9a5a64067a5dd9721241acabaa677 | p20@CAPZB |
| 1.31e-40 | FFCP PHASE1:Hg19::chr1:19811132..19811155,-#_2da9a5a64067a5dd9721241acabaa677 | p20@CAPZB |
| 1.8e-38 | FFCP PHASE2:Hg19::chr2:12248310..12248334,-#_72a46cf7ab827fc3d3b9384f2b71f12c | p@chr2:12248310..12248334, - |
| 1.8e-38 | FFCP PHASE1:Hg19::chr2:12248310..12248334,-#_72a46cf7ab827fc3d3b9384f2b71f12c | p@chr2:12248310..12248334, - |
| 2.75e-34 | FFCP PHASE2:Hg19::chr14:61190754..61190776,-#_7b2da784d4d22535a4c7d0a064d50666 | p6@SIX4 |
| 2.75e-34 | FFCP PHASE1:Hg19::chr14:61190754..61190776,-#_7b2da784d4d22535a4c7d0a064d50666 | p6@SIX4 |
| 5.96e-34 | FFCP PHASE2:Hg19::chr13:51101468..51101499,-#_ffc341580f0556b63f2d4856a6993a1b | p1@ENST00000428276 |
| 5.96e-34 | FFCP PHASE2:Hg19::chr4:88727274..88727278,+#_ffc341580f0556b63f2d4856a6993a1b | p@chr4:88727274..88727278, + |
| 5.96e-34 | FFCP PHASE2:Hg19::chr11:93468399..93468405,-#_ffc341580f0556b63f2d4856a6993a1b | p19@TAF1D, p1@SNORA40 |
| 5.96e-34 | FFCP PHASE1:Hg19::chr13:51101468..51101499,-#_ffc341580f0556b63f2d4856a6993a1b | p1@ENST00000428276 |
| 5.96e-34 | FFCP PHASE1:Hg19::chr4:88727274..88727278,+#_ffc341580f0556b63f2d4856a6993a1b | p@chr4:88727274..88727278, + |
| 5.96e-34 | FFCP PHASE1:Hg19::chr11:93468399..93468405,-#_ffc341580f0556b63f2d4856a6993a1b | p19@TAF1D, p1@SNORA40 |
| 2.09e-33 | FFCP PHASE2:Hg19::chr4:13546130..13546145,-#_e3c5e1ff64b2fc3f184feeaf2e7f6dc0 | p4@NKX3-2 |
| 2.09e-33 | FFCP PHASE1:Hg19::chr4:13546130..13546145,-#_e3c5e1ff64b2fc3f184feeaf2e7f6dc0 | p4@NKX3-2 |
| 4.01e-31 | FFCP PHASE1:Hg19::chr7:18832913..18832946,+#_18adc13359a7fa12a7b74b392ddba0df | p19@HDAC9 |
| 4.01e-31 | FFCP PHASE2:Hg19::chr7:18832913..18832946,+#_18adc13359a7fa12a7b74b392ddba0df | p19@HDAC9 |
| 1.98e-30 | FFCP PHASE2:Hg19::chr2:241897125..241897142,-#_f29ba3fffd09d0e09c8dcab5d20e8a15 | p@chr2:241897125..241897142, - |
| 1.98e-30 | FFCP PHASE1:Hg19::chr2:241897125..241897142,-#_f29ba3fffd09d0e09c8dcab5d20e8a15 | p@chr2:241897125..241897142, - |
| 4.84e-30 | FFCP PHASE1:Hg19::chr3:80727046..80727051,-#_187d3fb745efe2e3457808cccbaacc9b | p@chr3:80727046..80727051, - |
| 4.84e-30 | FFCP PHASE2:Hg19::chr3:80727046..80727051,-#_187d3fb745efe2e3457808cccbaacc9b | p@chr3:80727046..80727051, - |
| 7.46e-30 | FFCP PHASE2:Hg19::chr7:158224707..158224729,-#_65160431060517f4c381e62645f15c2a | p@chr7:158224707..158224729, - |
| 7.46e-30 | FFCP PHASE1:Hg19::chr7:158224707..158224729,-#_65160431060517f4c381e62645f15c2a | p@chr7:158224707..158224729, - |
| 1.48e-29 | FFCP PHASE1:Hg19::chr1:65888177..65888194,+#_fba4f533158d57ab030828c7e33a3b39 | p@chr1:65888177..65888194, + |
| 1.48e-29 | FFCP PHASE2:Hg19::chr1:65888177..65888194,+#_fba4f533158d57ab030828c7e33a3b39 | p@chr1:65888177..65888194, + |
| 2.72e-28 | FFCP PHASE2:Hg19::chr14:100848311..100848321,+#_1122fcc8d470776b5c9ed6a92ae634c1 | p5@WDR25 |
| 2.72e-28 | FFCP PHASE1:Hg19::chr14:100848311..100848321,+#_1122fcc8d470776b5c9ed6a92ae634c1 | p5@WDR25 |
| 3.26e-27 | FFCP PHASE2:Hg19::chr1:78695274..78695292,+#_792c026113ad2fc316b6a9d9e2852f49 | p1@MGC27382 |
| 3.26e-27 | FFCP PHASE1:Hg19::chr1:78695274..78695292,+#_792c026113ad2fc316b6a9d9e2852f49 | p1@MGC27382 |
| 6.92e-27 | FFCP PHASE1:Hg19::chr1:19778678..19778689,-#_caea250b0330fe27d6e99dd0b7b1496a | p@chr1:19778678..19778689, - |
| 6.92e-27 | FFCP PHASE2:Hg19::chr1:19778678..19778689,-#_caea250b0330fe27d6e99dd0b7b1496a | p@chr1:19778678..19778689, - |
| 1.46e-26 | FFCP PHASE1:Hg19::chr7:18832834..18832859,+#_2f7a10ddee128986653a81509b65b4f7 | p18@HDAC9 |
| 1.46e-26 | FFCP PHASE2:Hg19::chr7:18832834..18832859,+#_2f7a10ddee128986653a81509b65b4f7 | p18@HDAC9 |
| 1.74e-26 | FFCP PHASE2:Hg19::chr4:156129991..156130013,+#_2a02f6ddec723a77d1a6dd4db996edbd | p2@NPY2R |
| 1.74e-26 | FFCP PHASE1:Hg19::chr4:156129991..156130013,+#_2a02f6ddec723a77d1a6dd4db996edbd | p2@NPY2R |
| 7.41e-26 | FFCP PHASE1:Hg19::chr14:61113228..61113233,-#_ac61b0901733d0b6614d238800371240 | p@chr14:61113228..61113233, - |
| 7.41e-26 | FFCP PHASE2:Hg19::chr14:61113228..61113233,-#_ac61b0901733d0b6614d238800371240 | p@chr14:61113228..61113233, - |
| 2.04e-25 | FFCP PHASE1:Hg19::chr7:27212374..27212387,-#_2c2b91e969124e891ea759ff54573f02 | p12@HOXA10 |
| 2.04e-25 | FFCP PHASE2:Hg19::chr7:27212374..27212387,-#_2c2b91e969124e891ea759ff54573f02 | p12@HOXA10 |
| 6.22e-25 | FFCP PHASE1:Hg19::chr14:23574186..23574212,-#_9ef9e90934a79b294365e47b86cd5fc5 | p1@uc010aki.1 |
| 6.22e-25 | FFCP PHASE2:Hg19::chr14:23574186..23574212,-#_9ef9e90934a79b294365e47b86cd5fc5 | p1@uc010aki.1 |
| 9.49e-25 | FFCP PHASE1:Hg19::chr20:21686317..21686350,+#_bd62e99ddc39b562f77e4aeb8f8c9316 | p1@PAX1 |
| 9.49e-25 | FFCP PHASE2:Hg19::chr20:21686317..21686350,+#_bd62e99ddc39b562f77e4aeb8f8c9316 | p1@PAX1 |
| 4.58e-24 | FFCP PHASE1:Hg19::chr5:140887761..140887777,+#_fadeaeb156a5711ecb39a7defce6aa53 | p@chr5:140887761..140887777, + |
| 4.58e-24 | FFCP PHASE2:Hg19::chr5:140887761..140887777,+#_fadeaeb156a5711ecb39a7defce6aa53 | p@chr5:140887761..140887777, + |
| 5.35e-24 | FFCP PHASE1:Hg19::chr20:21686290..21686311,+#_5a5e19ef742bf0ec9d400a58375c89e6 | p2@PAX1 |
| 5.35e-24 | FFCP PHASE2:Hg19::chr20:21686290..21686311,+#_5a5e19ef742bf0ec9d400a58375c89e6 | p2@PAX1 |
| 8.55e-24 | FFCP PHASE1:Hg19::chr7:18832759..18832786,+#_cf341a09d0858538bb5b2b98282fc131 | p16@HDAC9 |
| 8.55e-24 | FFCP PHASE2:Hg19::chr7:18832759..18832786,+#_cf341a09d0858538bb5b2b98282fc131 | p16@HDAC9 |
| 2.01e-23 | FFCP PHASE1:Hg19::chr4:77068930..77068959,-#_834bb0afe5216474def7cf1f9835dd9b | p4@NUP54 |
| 2.01e-23 | FFCP PHASE2:Hg19::chr4:77068930..77068959,-#_834bb0afe5216474def7cf1f9835dd9b | p4@NUP54 |
| 2.28e-23 | FFCP PHASE2:Hg19::chr4:13546632..13546662,-#_2be156d7dc30d8a4ea43a596aac46ae2 | p1@NKX3-2 |
| 2.28e-23 | FFCP PHASE1:Hg19::chr4:13546632..13546662,-#_2be156d7dc30d8a4ea43a596aac46ae2 | p1@NKX3-2 |
| 3.27e-23 | FFCP PHASE1:Hg19::chr14:23574164..23574179,-#_d4c24a1ceb2b02069e45a87331cef0a8 | p3@uc010aki.1 |
| 3.27e-23 | FFCP PHASE2:Hg19::chr14:23574164..23574179,-#_d4c24a1ceb2b02069e45a87331cef0a8 | p3@uc010aki.1 |
| 1.25e-22 | FFCP PHASE1:Hg19::chr1:78695343..78695353,+#_0da64b296480253cbcb6282783146047 | p2@ENST00000413519 |
| 1.25e-22 | FFCP PHASE2:Hg19::chr1:78695343..78695353,+#_0da64b296480253cbcb6282783146047 | p2@ENST00000413519 |
| 1.46e-22 | FFCP PHASE2:Hg19::chr9:123239747..123239765,-#_890f001f8a7346f0b44789f032ca6956 | p12@CDK5RAP2 |
| 1.46e-22 | FFCP PHASE1:Hg19::chr9:123239747..123239765,-#_890f001f8a7346f0b44789f032ca6956 | p12@CDK5RAP2 |
| 9.47e-22 | FFCP PHASE1:Hg19::chr1:171076859..171076870,+#_7c9cdf8ec6c429d4d3f2055965caf00c | p@chr1:171076859..171076870, + |
| 9.47e-22 | FFCP PHASE2:Hg19::chr1:171076859..171076870,+#_7c9cdf8ec6c429d4d3f2055965caf00c | p@chr1:171076859..171076870, + |
| 1.35e-21 | FFCP PHASE1:Hg19::chr7:100202784..100202796,-#_36d872a06c16c7f6c843ccb5fe0b7ff7 | p@chr7:100202784..100202796, - |
| 1.35e-21 | FFCP PHASE2:Hg19::chr7:100202784..100202796,-#_36d872a06c16c7f6c843ccb5fe0b7ff7 | p@chr7:100202784..100202796, - |
| 3.83e-21 | FFCP PHASE1:Hg19::chr14:37126814..37126834,+#_97e807756260f8e8cfd1378e48900c43 | p4@PAX9 |
| 3.83e-21 | FFCP PHASE2:Hg19::chr14:37126814..37126834,+#_97e807756260f8e8cfd1378e48900c43 | p4@PAX9 |
| 4.02e-21 | FFCP PHASE2:Hg19::chr3:176765178..176765190,-#_d52d5dbbda00e9deaab0a7532cfcf4a4 | p@chr3:176765178..176765190, - |
| 4.02e-21 | FFCP PHASE1:Hg19::chr3:176765178..176765190,-#_d52d5dbbda00e9deaab0a7532cfcf4a4 | p@chr3:176765178..176765190, - |
| 4.06e-21 | FFCP PHASE2:Hg19::chr1:19810947..19810977,-#_d0dbc3791eb4c579a7f03ae4e12cc084 | p17@CAPZB |
| 4.06e-21 | FFCP PHASE1:Hg19::chr1:19810947..19810977,-#_d0dbc3791eb4c579a7f03ae4e12cc084 | p17@CAPZB |
| 5.43e-21 | FFCP PHASE2:Hg19::chr12:54422268..54422278,+#_fb6380dae95693af4fb57a0b1b154848 | p8@HOXC6 |
| 5.43e-21 | FFCP PHASE1:Hg19::chr12:54422268..54422278,+#_fb6380dae95693af4fb57a0b1b154848 | p8@HOXC6 |
| 4.94e-20 | FFCP PHASE2:Hg19::chr17:38613285..38613298,-#_76cbc6f84a9552fed452dd88d516fd7b | p@chr17:38613285..38613298, - |
| 4.94e-20 | FFCP PHASE1:Hg19::chr17:38613285..38613298,-#_76cbc6f84a9552fed452dd88d516fd7b | p@chr17:38613285..38613298, - |
| 9.53e-20 | FFCP PHASE1:Hg19::chr20:43343596..43343608,+#_58e14cf665df29483074314583972d14 | p6@WISP2 |
| 9.53e-20 | FFCP PHASE2:Hg19::chr20:43343596..43343608,+#_58e14cf665df29483074314583972d14 | p6@WISP2 |
| 1.46e-19 | FFCP PHASE1:Hg19::chr1:78958320..78958332,+#_93b7654b8e3622ce084ba29ac7f03f94 | p2@PTGFR |
| 1.46e-19 | FFCP PHASE2:Hg19::chr1:78958320..78958332,+#_93b7654b8e3622ce084ba29ac7f03f94 | p2@PTGFR |
| 2.04e-19 | FFCP PHASE2:Hg19::chr4:70707689..70707711,-#_5381ebab2bcf4aafa2f6210999aee37e | p@chr4:70707689..70707711, - |
| 2.04e-19 | FFCP PHASE1:Hg19::chr4:70707689..70707711,-#_5381ebab2bcf4aafa2f6210999aee37e | p@chr4:70707689..70707711, - |
| 3.75e-19 | FFCP PHASE2:Hg19::chr14:37126870..37126882,+#_edba8f9b74c55b8d9bf141a19d41bb1d | p1@ENST00000555639 |
| 3.75e-19 | FFCP PHASE1:Hg19::chr14:37126870..37126882,+#_edba8f9b74c55b8d9bf141a19d41bb1d | p1@ENST00000555639 |
| 4.68e-19 | FFCP PHASE2:Hg19::chr2:12246664..12246694,+#_45d722775f0b480bebd6fe58e7f621b4 | p1@ENST00000449986 |
| 4.68e-19 | FFCP PHASE1:Hg19::chr2:12246664..12246694,+#_45d722775f0b480bebd6fe58e7f621b4 | p1@ENST00000449986 |
| 1.04e-18 | FFCP PHASE1:Hg19::chr3:158390171..158390180,-#_45a57f84ce1d41536372d71409ca0aa1 | p3@LXN |
| 1.04e-18 | FFCP PHASE2:Hg19::chr3:158390171..158390180,-#_45a57f84ce1d41536372d71409ca0aa1 | p3@LXN |
| 5.12e-18 | FFCP PHASE1:Hg19::chr6:112375300..112375334,+#_ac84cf8bc398581fe818fc0ade90faa3 | p1@WISP3 |
| 5.12e-18 | FFCP PHASE2:Hg19::chr6:112375300..112375334,+#_ac84cf8bc398581fe818fc0ade90faa3 | p1@WISP3 |
| 9.14e-18 | FFCP PHASE2:Hg19::chr8:77595678..77595688,+#_2cd97566b754dd832ab0278766c80382 | p9@ZFHX4 |
| 9.14e-18 | FFCP PHASE1:Hg19::chr8:77595678..77595688,+#_2cd97566b754dd832ab0278766c80382 | p9@ZFHX4 |
