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UBERON:0003061

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Name:blood island
Namespace:FANTOM
Definition:"Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP]. Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates[XAO]. Nests of developing blood cells arising late in the segmentation period from the intermediate mass, and located in the anterior-ventral tail, just posterior to the yolk extension[ZFA]." [PMID:9618755, Wikipedia:Blood_island_of_umbilical_vesicle, XAO:0000067, ZFIN:curator]
Xrefs:
links:

AAO:0011006
EFO:0003489
EHDAA2:0003241
ncithesaurus:Blood_Island
TAO:0000094
TE:E5.11.2.0.0.0.4
VHOG:0000085
XAO:0000067

ZFA:0000094
Synonyms: "blood island of umbilical vesicle" EXACT [Wikipedia:Blood_island]
"blood islands" EXACT PLURAL []
"caudal hematopoietic tissue" RELATED []
"insula sanguinea vesiculae umbilicalis" EXACT [Wikipedia:Blood_island]
"mesoderm blood islands" EXACT [EHDAA2:0003241]
"posterior blood island" RELATED []
"posterior ICM" RELATED []
"VBI" RELATED []
"ventral blood island" RELATED []
"ventral lateral plate mesoderm" BROAD []
Comments:Note EHDAA2 distinguishes 3 types - we opt for the mesoderm one
Alt_id: UBERON:XAO_0000067-ZFA_0000094
Subset: uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0005423(developing anatomical structure)
develops_from:UBERON:0003081(lateral plate mesoderm)
part_of:UBERON:0000922(embryo)



Children

develops from:UBERON:0002390 (hematopoietic system)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology




Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0003061 (blood island), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data











Property "Property value" (as page type) with input value "UBPROP:0000001 "Nests of developing blood cells arising late in the segmentation period from the intermediate mass, and located in the anterior-ventral tail, just posterior to the yolk extension. Kimmel et al, 1995.[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000001 "Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process., Property "Property value" (as page type) with input value "UBPROP:0000002 "relationship loss: part_of intermediate cell mass of mesoderm (TAO:0000033)[TAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.