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UBERON:0005876

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Name:undifferentiated genital tubercle
Namespace:FANTOM
Definition:"A genital tubercle is a body of tissue present in the development of the urinary and reproductive organs. It forms in the ventral, caudal region of mammalian embryos of both sexes, and eventually develops into a phallus. In the human fetus the genital tubercle develops around week 4 of gestation, and by week 9 becomes recognizably either a clitoris or penis. This should not be confused with the sinus tubercle which is a proliferation of endoderm induced by paramesonephic ducts. Even after the phallus is developed, the term genital tubercle remains, but only as the terminal end of it[2], which develops into either the glans penis or the glans clitoridis. The genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month is a major determinant of phallus size at birth.[WP]." [Wikipedia:Genital_tubercle]
Xrefs:
links:

EHDAA2:0000705
EHDAA:5925
EMAPA:17382
[ Gray1119.png Gray1119.png]

SCTID:308798005
Synonyms: "tuberculum phallicum; tuberculum genitale" RELATED LATIN [Wikipedia:Genital_tubercle]
Comments:Taxon notes: todo - add taxon constraints

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0005423(developing anatomical structure)
develops_from:UBERON:0004874(somatopleure)
part_of:UBERON:0009196(indifferent external genitalia)



Children

develops from:UBERON:0000989 (penis)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology




Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0005876 (undifferentiated genital tubercle), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data