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Revision as of 17:08, 15 June 2012

Name:renal glomerulus
Definition:"A capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney[GO]." [MP:0005325, Wikipedia:Glomerulus]
Xrefs:
links:

AAO:0010388
BTO:0000530
EFO:0003667
EV:0100386
FMA:15624
[1]
[ 200px-Gray1130.svg.png 200px-Gray1130.svg.png]
MA:0001657
MESH:A.05.810.453.736.520
ncithesaurus:Glomerulus
XAO:0000146

ZFA:0001288
Synonyms: "glomerular capillary tuft" RELATED [ZFA:0001288]
"glomerular tuft" RELATED []
"glomerulus" BROAD []
"malphigian glomerulus" RELATED [BTO:0000530]
"renal corpuscle" RELATED []
Comments:ZFA - The multi-tissue structure where the glomerular basement membrane supported by mesonephric podocytes filters blood from the glomerular capillaries. TODO - split glomerulus and glomerular tuft? DONE. GUDMAP: 'Together, the Bowman窶冱 capsule and the glomerulus comprise the definitive renal corpuscle.' - here the glomerulus is part of the capsule?
Subset: vertebrate_core
Created by:Melissa Haendel
Creation date:2009-06-18T09:26:37Z

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0000064(organ part),UBERON:0004120(mesoderm-derived structure)
develops_from:UBERON:0003220(metanephric mesenchyme),UBERON:0005749(glomerular tuft)
part_of:UBERON:0001229(renal corpuscle)



Children

part of:CL:0002188 (glomerular endothelial cell),UBERON:0002319 (mesangium),CL:1000746 (glomerular cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000074 (renal glomerulus), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data


P-valueFFCPShort description
6.87e-64FFCP PHASE1:Hg19::chr2:120409486..120409492,+#_4d7bb32267b0b9fb2a444b7a94d53bd5p@chr2:120409486..120409492, +
6.87e-64FFCP PHASE2:Hg19::chr2:120409486..120409492,+#_4d7bb32267b0b9fb2a444b7a94d53bd5p@chr2:120409486..120409492, +
9.62e-40FFCP PHASE2:Hg19::chr1:94713418..94713436,+#_97659a7127319b72d9dbe5a7f616805ep1@ENST00000413103
9.62e-40FFCP PHASE1:Hg19::chr1:94713418..94713436,+#_97659a7127319b72d9dbe5a7f616805ep1@ENST00000413103
1.16e-36FFCP PHASE1:Hg19::chr17:79426453..79426462,+#_4a9985f04e03bfa4e388e4a2c72a694ap@chr17:79426453..79426462, +
1.16e-36FFCP PHASE2:Hg19::chr17:79426453..79426462,+#_4a9985f04e03bfa4e388e4a2c72a694ap@chr17:79426453..79426462, +
1.31e-36FFCP PHASE2:Hg19::chr8:77557753..77557755,-#_71d555d3b0dee30fe005fea652dc57e6p@chr8:77557753..77557755, -
1.31e-36FFCP PHASE1:Hg19::chr8:77557753..77557755,-#_71d555d3b0dee30fe005fea652dc57e6p@chr8:77557753..77557755, -
5.58e-32FFCP PHASE1:Hg19::chr1:32042764..32042776,+#_30edbc2fbcd503ad7e75d1193e96a5efp6@TINAGL1
5.58e-32FFCP PHASE2:Hg19::chr1:32042764..32042776,+#_30edbc2fbcd503ad7e75d1193e96a5efp6@TINAGL1
1.53e-30FFCP PHASE2:Hg19::chr15:91416076..91416089,+#_18088851ade55b5298aa2c0484dcca37p9@FURIN
1.53e-30FFCP PHASE1:Hg19::chr15:91416076..91416089,+#_18088851ade55b5298aa2c0484dcca37p9@FURIN
3.83e-30FFCP PHASE2:Hg19::chr20:6034598..6034603,-#_67acd62f283b10e4a12b18d74e0c8ee0p7@LRRN4
3.83e-30FFCP PHASE1:Hg19::chr20:6034598..6034603,-#_67acd62f283b10e4a12b18d74e0c8ee0p7@LRRN4
1.78e-29FFCP PHASE1:Hg19::chr1:42777312..42777314,+#_733f9dc9e8b9f2d83638ada760f03d76p@chr1:42777312..42777314, +
1.78e-29FFCP PHASE1:Hg19::chr2:26700984..26700993,-#_733f9dc9e8b9f2d83638ada760f03d76p7@OTOF
1.78e-29FFCP PHASE1:Hg19::chr6:18225523..18225534,-#_733f9dc9e8b9f2d83638ada760f03d76p@chr6:18225523..18225534, -
1.78e-29FFCP PHASE2:Hg19::chr22:47030082..47030087,+#_733f9dc9e8b9f2d83638ada760f03d76p@chr22:47030082..47030087, +
1.78e-29FFCP PHASE1:Hg19::chr2:26700331..26700340,-#_733f9dc9e8b9f2d83638ada760f03d76p@chr2:26700331..26700340, -
1.78e-29FFCP PHASE2:Hg19::chr1:42777312..42777314,+#_733f9dc9e8b9f2d83638ada760f03d76p@chr1:42777312..42777314, +
1.78e-29FFCP PHASE1:Hg19::chr22:47030082..47030087,+#_733f9dc9e8b9f2d83638ada760f03d76p@chr22:47030082..47030087, +
1.78e-29FFCP PHASE2:Hg19::chr2:26700984..26700993,-#_733f9dc9e8b9f2d83638ada760f03d76p7@OTOF
1.78e-29FFCP PHASE2:Hg19::chr6:18225523..18225534,-#_733f9dc9e8b9f2d83638ada760f03d76p@chr6:18225523..18225534, -
1.78e-29FFCP PHASE2:Hg19::chr2:26700331..26700340,-#_733f9dc9e8b9f2d83638ada760f03d76p@chr2:26700331..26700340, -
7.96e-27FFCP PHASE2:Hg19::chr10:3477893..3477912,-#_a2916e13c10b3c76d9082e1de3869b8fp@chr10:3477893..3477912, -
7.96e-27FFCP PHASE1:Hg19::chr10:3477893..3477912,-#_a2916e13c10b3c76d9082e1de3869b8fp@chr10:3477893..3477912, -
6.29e-26FFCP PHASE2:Hg19::chr1:172926077..172926120,-#_0c95fa40010870ab14a9e92fbbef39e3p@chr1:172926077..172926120, -
6.29e-26FFCP PHASE1:Hg19::chr1:172926077..172926120,-#_0c95fa40010870ab14a9e92fbbef39e3p@chr1:172926077..172926120, -
6.32e-26FFCP PHASE2:Hg19::chrX:128782722..128782738,-#_87b777cedf25092d016c0552504ed12cp5@APLN
6.32e-26FFCP PHASE1:Hg19::chrX:128782722..128782738,-#_87b777cedf25092d016c0552504ed12cp5@APLN
9.89e-26FFCP PHASE2:Hg19::chr2:693380..693398,+#_6115a428bb677e4243c3a9f2f9d6f4c1p@chr2:693380..693398, +
9.89e-26FFCP PHASE1:Hg19::chr2:693380..693398,+#_6115a428bb677e4243c3a9f2f9d6f4c1p@chr2:693380..693398, +
1.28e-23FFCP PHASE2:Hg19::chr2:133426030..133426041,-#_3596fccbe3f03a8ebc4ba3cea360941ap@chr2:133426030..133426041, -
1.28e-23FFCP PHASE1:Hg19::chr6:84849252..84849259,+#_3596fccbe3f03a8ebc4ba3cea360941ap@chr6:84849252..84849259, +
1.28e-23FFCP PHASE1:Hg19::chr2:133426030..133426041,-#_3596fccbe3f03a8ebc4ba3cea360941ap@chr2:133426030..133426041, -
1.28e-23FFCP PHASE2:Hg19::chr6:84849252..84849259,+#_3596fccbe3f03a8ebc4ba3cea360941ap@chr6:84849252..84849259, +
1.44e-23FFCP PHASE1:Hg19::chr1:51791596..51791607,-#_5a11f540c09519e76589bbea4a0d900ep23@TTC39A
1.44e-23FFCP PHASE1:Hg19::chr7:28998254..28998261,-#_5a11f540c09519e76589bbea4a0d900ep10@TRIL
1.44e-23FFCP PHASE2:Hg19::chr1:51791596..51791607,-#_5a11f540c09519e76589bbea4a0d900ep23@TTC39A
1.44e-23FFCP PHASE2:Hg19::chr7:28998254..28998261,-#_5a11f540c09519e76589bbea4a0d900ep10@TRIL
1.61e-23FFCP PHASE2:Hg19::chr7:4051097..4051112,+#_c69b8f50c48e31ab6dd3a1d32b2060d8p@chr7:4051097..4051112, +
1.61e-23FFCP PHASE2:Hg19::chr15:85403302..85403304,+#_c69b8f50c48e31ab6dd3a1d32b2060d8p@chr15:85403302..85403304, +
1.61e-23FFCP PHASE1:Hg19::chr7:4051097..4051112,+#_c69b8f50c48e31ab6dd3a1d32b2060d8p@chr7:4051097..4051112, +
1.61e-23FFCP PHASE1:Hg19::chr15:85403302..85403304,+#_c69b8f50c48e31ab6dd3a1d32b2060d8p@chr15:85403302..85403304, +
1.8e-23FFCP PHASE2:Hg19::chr16:2141529..2141537,+#_a0324e5c27913e3e5ccaf2be03ebcfcep@chr16:2141529..2141537, +
1.8e-23FFCP PHASE1:Hg19::chr16:2141529..2141537,+#_a0324e5c27913e3e5ccaf2be03ebcfcep@chr16:2141529..2141537, +
2.92e-22FFCP PHASE2:Hg19::chr5:74244100..74244117,+#_0b956ebd98481844f07d4d38dd9183acp@chr5:74244100..74244117, +
2.92e-22FFCP PHASE1:Hg19::chr5:74244100..74244117,+#_0b956ebd98481844f07d4d38dd9183acp@chr5:74244100..74244117, +
5.69e-22FFCP PHASE2:Hg19::chr5:148651758..148651769,-#_1f987939d8ad71f759f0735c39eeb874p@chr5:148651758..148651769, -
5.69e-22FFCP PHASE1:Hg19::chr5:148651758..148651769,-#_1f987939d8ad71f759f0735c39eeb874p@chr5:148651758..148651769, -
2.9e-21FFCP PHASE1:Hg19::chr16:86768403..86768437,+#_ee2df898c8d0a199de08eb57871e65b9p@chr16:86768403..86768437, +
2.9e-21FFCP PHASE2:Hg19::chr16:86768403..86768437,+#_ee2df898c8d0a199de08eb57871e65b9p@chr16:86768403..86768437, +
4.78e-21FFCP PHASE1:Hg19::chr17:2076002..2076026,-#_576a0f2ec94151fab3108586ea9e5184p@chr17:2076002..2076026, -
4.78e-21FFCP PHASE2:Hg19::chr17:2076002..2076026,-#_576a0f2ec94151fab3108586ea9e5184p@chr17:2076002..2076026, -
1.26e-20FFCP PHASE1:Hg19::chr1:32712897..32712909,+#_92f3ba778dd5ee2c8f4c475a7b022437p3@FAM167B
1.26e-20FFCP PHASE2:Hg19::chr1:32712897..32712909,+#_92f3ba778dd5ee2c8f4c475a7b022437p3@FAM167B
2.32e-20FFCP PHASE2:Hg19::chr11:124628392..124628427,-#_d106ab53c243d5e82e77ba322565d5d9p@chr11:124628392..124628427, -
2.32e-20FFCP PHASE1:Hg19::chr11:124628392..124628427,-#_d106ab53c243d5e82e77ba322565d5d9p@chr11:124628392..124628427, -
3.42e-20FFCP PHASE2:Hg19::chr3:98591021..98591026,-#_24e37e2c0cceba8385f7b4670d941993p1@ENST00000487339
3.42e-20FFCP PHASE1:Hg19::chr3:98591021..98591026,-#_24e37e2c0cceba8385f7b4670d941993p1@ENST00000487339
3.44e-20FFCP PHASE1:Hg19::chr19:47231340..47231383,-#_c6867c006a2cf50541037386f72e1cd2p@chr19:47231340..47231383, -
3.44e-20FFCP PHASE2:Hg19::chr19:47231340..47231383,-#_c6867c006a2cf50541037386f72e1cd2p@chr19:47231340..47231383, -
3.58e-20FFCP PHASE1:Hg19::chr19:1826957..1826984,-#_fe561ea1d4f590d60150e7d16136051cp@chr19:1826957..1826984, -
3.58e-20FFCP PHASE2:Hg19::chr19:1826957..1826984,-#_fe561ea1d4f590d60150e7d16136051cp@chr19:1826957..1826984, -
4.39e-20FFCP PHASE1:Hg19::chr4:38057595..38057624,-#_fd92ee6c214b52445766a94483f7e594p@chr4:38057595..38057624, -
4.39e-20FFCP PHASE2:Hg19::chr4:38057595..38057624,-#_fd92ee6c214b52445766a94483f7e594p@chr4:38057595..38057624, -
7.13e-20FFCP PHASE2:Hg19::chr2:133426106..133426117,-#_2d8d19251ba0293d9080956690525156p@chr2:133426106..133426117, -
7.13e-20FFCP PHASE1:Hg19::chr2:133426106..133426117,-#_2d8d19251ba0293d9080956690525156p@chr2:133426106..133426117, -
7.84e-20FFCP PHASE2:Hg19::chr15:36653709..36653720,-#_333ef571f59da48992ec5476937e15dfp@chr15:36653709..36653720, -
7.84e-20FFCP PHASE1:Hg19::chr9:35753821..35753835,-#_333ef571f59da48992ec5476937e15dfp@chr9:35753821..35753835, -
7.84e-20FFCP PHASE1:Hg19::chr15:36653709..36653720,-#_333ef571f59da48992ec5476937e15dfp@chr15:36653709..36653720, -
7.84e-20FFCP PHASE2:Hg19::chr9:35753821..35753835,-#_333ef571f59da48992ec5476937e15dfp@chr9:35753821..35753835, -
8.62e-20FFCP PHASE1:Hg19::chr4:145568170..145568180,-#_c510e71931ea3197e9eb2d52bc4ab041p@chr4:145568170..145568180, -
8.62e-20FFCP PHASE2:Hg19::chr4:145568170..145568180,-#_c510e71931ea3197e9eb2d52bc4ab041p@chr4:145568170..145568180, -
1.04e-19FFCP PHASE2:Hg19::chr19:38397228..38397266,-#_2c6ea6663e56382ce8aa86608b09866ep1@WDR87
1.04e-19FFCP PHASE1:Hg19::chr19:38397228..38397266,-#_2c6ea6663e56382ce8aa86608b09866ep1@WDR87
1.15e-19FFCP PHASE2:Hg19::chr14:91270270..91270281,-#_cfeadbad5e4c98a42b21b631a1b759bep@chr14:91270270..91270281, -
1.15e-19FFCP PHASE1:Hg19::chr14:91270270..91270281,-#_cfeadbad5e4c98a42b21b631a1b759bep@chr14:91270270..91270281, -
2.44e-19FFCP PHASE2:Hg19::chr12:52306196..52306215,+#_682c6ac922ea900a70c2691c8c7eb067p6@ACVRL1
2.44e-19FFCP PHASE1:Hg19::chr12:52306196..52306215,+#_682c6ac922ea900a70c2691c8c7eb067p6@ACVRL1
3.27e-19FFCP PHASE2:Hg19::chr3:43538305..43538325,-#_104da4dd9fdcb9be85ecb2ee263e2b05p@chr3:43538305..43538325, -
3.27e-19FFCP PHASE1:Hg19::chr3:43538305..43538325,-#_104da4dd9fdcb9be85ecb2ee263e2b05p@chr3:43538305..43538325, -
4.64e-19FFCP PHASE1:Hg19::chr17:171147..171161,+#_b49e28446bfa9eff58600698b6b65be5p@chr17:171147..171161, +
4.64e-19FFCP PHASE2:Hg19::chr17:171147..171161,+#_b49e28446bfa9eff58600698b6b65be5p@chr17:171147..171161, +
5.39e-19FFCP PHASE1:Hg19::chr1:22211913..22211920,+#_15a2fe930cb511c22d7f767f86f9a5f1p@chr1:22211913..22211920, +
5.39e-19FFCP PHASE2:Hg19::chr1:22211913..22211920,+#_15a2fe930cb511c22d7f767f86f9a5f1p@chr1:22211913..22211920, +
1.99e-18FFCP PHASE1:Hg19::chr7:27219833..27219845,-#_3704e2ce1e7130bd1c46bfb0e3718dccp7@HOXA10
1.99e-18FFCP PHASE2:Hg19::chr7:27219833..27219845,-#_3704e2ce1e7130bd1c46bfb0e3718dccp7@HOXA10
2.69e-18FFCP PHASE2:Hg19::chr1:32041957..32041990,+#_7be61c06df7fd3ca4ec7ff76b9141200p3@TINAGL1
2.69e-18FFCP PHASE1:Hg19::chr1:32041957..32041990,+#_7be61c06df7fd3ca4ec7ff76b9141200p3@TINAGL1
4.1e-18FFCP PHASE2:Hg19::chr6:132270228..132270243,-#_2fe4b0fcc4156832096f8130c2320380p17@CTGF
4.1e-18FFCP PHASE1:Hg19::chr6:132270228..132270243,-#_2fe4b0fcc4156832096f8130c2320380p17@CTGF
5.7e-18FFCP PHASE2:Hg19::chr11:940729..940745,+#_78b62f5748371434c91c898b09c8dca2p5@AP2A2
5.7e-18FFCP PHASE1:Hg19::chr11:940729..940745,+#_78b62f5748371434c91c898b09c8dca2p5@AP2A2
6.5e-18FFCP PHASE2:Hg19::chr19:42007093..42007107,-#_1606ac664f69b9e814bfd5c53bafc807p@chr19:42007093..42007107, -
6.5e-18FFCP PHASE1:Hg19::chr19:42007093..42007107,-#_1606ac664f69b9e814bfd5c53bafc807p@chr19:42007093..42007107, -
6.99e-18FFCP PHASE2:Hg19::chrX:128781853..128781866,-#_7f66d6c54689ffb4afcb079c0def1444p@chrX:128781853..128781866, -
6.99e-18FFCP PHASE1:Hg19::chrX:128781853..128781866,-#_7f66d6c54689ffb4afcb079c0def1444p@chrX:128781853..128781866, -
1.24e-17FFCP PHASE2:Hg19::chr16:86604624..86604648,+#_2a3816c46b6d9ddb4c80866bcc383355p@chr16:86604624..86604648, +
1.24e-17FFCP PHASE1:Hg19::chr16:86604624..86604648,+#_2a3816c46b6d9ddb4c80866bcc383355p@chr16:86604624..86604648, +