MCL coexpression mm9:516: Difference between revisions
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{{MCL_coexpression_mm9 | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=0.0738156279963256,1.26158141408373,1.20248046897606,1.30048980477689,1.32962685650565,0.621110719041542,0.624433189139552,-0.011888404574096,-0.0759220124616582,-0.0486666624000875,-0.193139231581271,-0.163234565239726,-0.00359924859943731,-0.00297450238976905,-0.149125726837451,-0.158926912085744,-0.194114725742923,-0.08222070199317,-0.0905378559696345,-0.0772057209372674,0.685791213556869,-0.109077660886431,-0.158226224554812,0.919445841147558,0.953005016471978,1.11413276969329,0.990752358168292,0.916310545611143,1.18921437736949,1.10907177063761,0.75347681150667,-0.223376267757119,-0.195846756119705,-0.363968511927784,0.353421344138944,0.331499364243059,0.340206204540411,-0.193307039254108,-0.104699026772299,-0.135448560221453,-0.179416268466709,-0.150816834964858,-0.164720451173845,-0.00262261090384707,0.0024195409343152,-0.0316194154162729,0.031138812131364,0.00377651911879564,0.0673636531784245,0.0598352856844268,0.0289713988034489,-0.0192558436029755,-0.0989356410046019,-0.0222873395611463,-0.0209955762132063,-0.024822021043242,0.00741468791634683,0.046094040193219,-0.113076855404232,-0.129768618709186,-0.118393438356993,-0.0351439340167388,-0.0258209126545706,-0.0954789128281311,-0.0711256757212487,-0.0993495977443468,0.0352511390620754,0.076508592963391,-0.191088429018162,-0.183053100529234,-0.196951920840201,-0.00576277422926958,0.0105884579135024,-0.177016548508732,-0.165435832201255,-0.147096459237028,0.0153768522487539,0.0316299001651157,0.0113168922326981,-0.116001296104426,-0.104136889632161,-0.130763832881572,0.0422564808472463,0.0299612682448569,0.0444082370993851,0.0143520319427519,-0.0167875081008104,-0.0689393407047172,-0.124600981960812,-0.0975674206208156,0.146887721107421,0.227977784851853,0.368618967711286,0.410356014595816,0.494186788252737,0.412360275981488,0.65261842249,-0.131409413569172,-0.182131971854316,-0.1542117299087,0.1207153917337,-0.148297552216422,-0.205407809562864,-0.273080189862622,-0.055406490642305,-0.0578892476052135,-0.091400445857604,0.809074292132365,-0.0399796285536873,0.0127207991092231,-0.0420318270297119,0.00158162747309339,0.0475582303841068,0.0320716304665609,-0.00575167008665705,0.0257370734676514,0.780072046660282,-0.0327537112936803,-0.0993548338485914,-0.00428943160369333,0.0220224070719218,0.000405163634177124,0.466964267619403,0.0718546516666936,0.113767323423304,1.05304041338325,-0.135001995396494,-0.142461948219736,-0.149445894413679,0.0370710660094101,0.00424514243872422,-0.0571637732734072,0.0668543453619686,0.080369781067136,0.0324200266209598,0.0482358577294998,0.0252444828188037,0.0680681700998378,0.0781357339482702,0.115155543452214,-0.10792939556848,-0.137215607850221,-0.134510603045511,-0.0228133017988667,-0.0623803005101023,-0.0681873385046701,-0.0470860050992643,0.0757346925084709,-0.190257109455419,-0.104011086395819,-0.094987631323745,-0.0673906163495583,-0.0292085306405429,0.0372364564585105,0.011340047239223,0.0112799459840163,-0.145112654448457,-0.157820906122367,-0.142556396475764,0.0397967022274891,0.0454511391813749,0.0235075588005877,0.0443941268329283,0.028779145540647,0.0281867579925954,0.0234181942371386,0.0157362833939088,0.0227387900418087,0.0283756475139137,0.0446090278515335,0.0522546427161383,0.0690915271278459,0.0671249539305936,0.0743534912010666,0.0621177827414365,-0.047293770556134,1.20135485807057,0.997993620486105,-0.0844414294195379,-0.0428884669275975,0.216940076052017,0.612555817429455,0.760550986180886,0.886201618995459,1.01953061612319,0.941806980524122,0.838839446200249,0.794312910906108,0.808915006695388,1.03608505205808,0.982876326049918,1.01330219278386,0.0341584173647686,0.213862685507555,0.518146036111132,0.62131614973387,0.781732337359092,0.790066456905172,0.980512079507175,1.22875429081597,1.23920534729419,1.26460580856319,0.465400165175858,-0.0569126256072501,-0.0400542206840757,0.0169654308652145,0.0846508556786007,0.211314364191763,0.253835621326755,0.324224478489314,0.269764275906059,0.340061297738299,0.405457796583283,0.35956327736995,0.415907013989446,0.361962629277378,0.363882980647904,0.494651608404659,0.0753628534996801,-0.0515383161269975,-0.0561484057312185,-0.0574960980047074,-0.0326049872651316,0.0286380232849285,0.0734506644942906,0.0803722686594658,0.00368962138525893,0.0146840561136932,0.0169522447647619,0.0911860839834674,0.0661267390432092,0.0857789065813778,-0.186683152266751,-0.130593955004101,-0.0382540630940088,0.00577523157429453,0.0557421346663849,0.0563840644396859,-0.145738082633082,0.0702862165743526,-0.0764000474221078,-0.0801382220089487,-0.0417843259060942,-0.0984792002417418,-0.073039612480836,-0.0773499261496522,-0.0890519131729747,-0.0674494022453115,-0.0949445895721867,0.0706513514326681,0.0600865899476644,0.0651826968407316,0.00163061265071495,0.0967607942820902,-0.0288525465762174,0.0285652605636124,0.0246832618822991,0.0146593031108576,0.0233813166516611,0.0272838950068732,0.453987655995545,0.0641946778540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g ATPase activity;0.000649603968083954;11931,11928!GO:0043492;ATPase activity, coupled to movement of substances;0.000649603968083954;11931,19300,11928!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000649603968083954;11931,19300,11928!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000649603968083954;11931,19300,11928!GO:0015399;primary active transmembrane transporter activity;0.000649603968083954;11931,19300,11928!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000649603968083954;11931,19300,11928!GO:0042623;ATPase activity, coupled;0.00299468280554583;11931,19300,11928!GO:0016887;ATPase activity;0.00406725087011969;11931,19300,11928!GO:0022857;transmembrane transporter activity;0.00489032804989519;11931,19300,11928,20532!GO:0022804;active transmembrane transporter activity;0.00489032804989519;11931,19300,11928!GO:0015662;ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;0.00489032804989519;11931,11928!GO:0016323;basolateral plasma membrane;0.00489032804989519;11931,11928!GO:0003869;4-nitrophenylphosphatase activity;0.00489032804989519;11928!GO:0031944;negative regulation of glucocorticoid metabolic process;0.00489032804989519;11928!GO:0003812;alternative-complement-pathway C3/C5 convertase activity;0.00489032804989519;14962!GO:0031947;negative regulation of glucocorticoid biosynthetic process;0.00489032804989519;11928!GO:0050104;L-gulonate 3-dehydrogenase activity;0.00489032804989519;68631!GO:0045989;positive regulation of striated muscle contraction;0.00489032804989519;11928!GO:0005890;sodium:potassium-exchanging ATPase complex;0.00489032804989519;11928!GO:0031402;sodium ion binding;0.00540356830941047;11931,11928!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00540356830941047;11931,11928!GO:0016787;hydrolase activity;0.00665296331702059;11931,19300,11928,20532,14962!GO:0017111;nucleoside-triphosphatase activity;0.00665296331702059;11931,19300,11928!GO:0016462;pyrophosphatase activity;0.00665296331702059;11931,19300,11928!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;0.00665296331702059;11931,19300,11928!GO:0031946;regulation of glucocorticoid biosynthetic process;0.00665296331702059;11928!GO:0006942;regulation of striated muscle contraction;0.00665296331702059;11928!GO:0016817;hydrolase activity, acting on acid anhydrides;0.00665296331702059;11931,19300,11928!GO:0030955;potassium ion binding;0.00719419230784296;11931,11928!GO:0006814;sodium ion transport;0.00720758775445428;11931,11928!GO:0051240;positive regulation of multicellular organismal process;0.00760633875252806;11928,14962!GO:0030641;cellular hydrogen ion homeostasis;0.00844369105956371;11928!GO:0031943;regulation of glucocorticoid metabolic process;0.00844369105956371;11928!GO:0006813;potassium ion transport;0.0117900740447466;11931,11928!GO:0006704;glucocorticoid biosynthetic process;0.0122164455235837;11928!GO:0045823;positive regulation of heart contraction;0.0122164455235837;11928!GO:0004556;alpha-amylase activity;0.0122164455235837;20532!GO:0045933;positive regulation of muscle contraction;0.0122164455235837;11928!GO:0031420;alkali metal ion binding;0.013695949110629;11931,11928!GO:0045822;negative regulation of heart contraction;0.0139240775993345;11928!GO:0019218;regulation of steroid metabolic process;0.014437015586575;11928!GO:0015991;ATP hydrolysis coupled proton transport;0.014437015586575;11928!GO:0030004;cellular monovalent inorganic cation homeostasis;0.014437015586575;11928!GO:0016160;amylase activity;0.014437015586575;20532!GO:0055067;monovalent inorganic cation homeostasis;0.014437015586575;11928!GO:0015988;energy coupled proton transport, against electrochemical gradient;0.0161376681274488;11928!GO:0008211;glucocorticoid metabolic process;0.0177651960227553;11928!GO:0006957;complement activation, alternative pathway;0.0193241698064379;14962!GO:0002026;regulation of the force of heart contraction;0.0245945883898245;11928!GO:0051239;regulation of multicellular organismal process;0.0258274784993673;11928,14962!GO:0015672;monovalent inorganic cation transport;0.0267549287020553;11931,11928!GO:0019216;regulation of lipid metabolic process;0.033833195127419;11928!GO:0030317;sperm motility;0.0366749634372288;11928!GO:0006810;transport;0.0425450358553478;11931,19300,11928,20532!GO:0030001;metal ion transport;0.0449090202084987;11931,11928!GO:0051234;establishment of localization;0.0451118381541869;11931,19300,11928,20532!GO:0042383;sarcolemma;0.0454074163261384;11928!GO:0051241;negative regulation of multicellular organismal process;0.0454261965387048;11928!GO:0006941;striated muscle contraction;0.0454261965387048;11928!GO:0042493;response to drug;0.0462005525431601;11928!GO:0006937;regulation of muscle 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| |||
|coexpression_dpi_cluster_scores_median=0,1.21867062869683,1.23451068218204,1.42587921325803,1.46100059732527,0.558768034106336,0.45516907499068,0,0,0,0,0,0,0,0,0,0,0,0,0,0.63491844234638,0,0,0.787606710402501,0.835112953651027,1.19287787034758,1.10324335985168,0.984673215196544,1.14790449212473,1.17809538395132,0.546315836052118,0,0,0,0.154114119472385,0.161996922118341,0.0806875710728457,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0505643030049625,0,0,0.16673723800292,0.335390184642903,0.279948994901856,0.536598455085862,0,0,0,0,0,0,0,0,0,0,0.791277754414645,0,0,0,0,0,0,0,0,0.728604746544866,0,0,0,0,0,0.097479468063821,0,0,1.12271984260098,0,0,0,0,0,0,0,0,0,0,0,0.0254617646470484,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.34319194654611,1.131462367417,0,0,0.180547299228779,0.533553435744405,0.626795053444836,0.716012946345709,1.15201395689681,0.816177635177496,0.676001977516405,0.682050232199499,0.639658949828713,1.14753695956745,0.980441207592981,1.07284530780257,0,0.110485837356543,0.43578255093731,0.497003007844606,0.679993126675762,0.760673101120654,0.979693069010632,1.23196526379542,1.30427253691066,1.40569187532029,0.24173429500414,0,0,0,0,0,0.098514232005992,0.0763766352940708,0.0609883447004885,0.0152681289255518,0.0210488915331602,0.144634124251959,0.195689402107255,0.13685944568926,0.0961492418804523,0.267128089483046,0,0,0,0,0,0,0,0,0,0,0,0.0319560611731326,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0141504240413807,0,0,0,0.0190074969839466,0,0,0,0,0.386560093397683,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0851612139959913,0.210337318511773,0,0,0,0,0,0,1.11953509734703,0,0,0,0,0,0,0,0,0,0,0,0,0,0.121893240712599,0.0824580172145032,0.242171024452522,0.0979056601324245,0.175102553922751,0,0.132510767213725,0,0,0,0,0,0,0,0,0.0222164848068354,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0431328842449674,0,0,0.105314621823962,0.105496805488301,0.103334802758287,0.0978461107777356,0.098117166361508,0.104067138442029,0.0910388974522726,0.0756764467994078,0.0898139621139603,0,0.0512874344664669,0.0666789030790138,0.0921166462441741,0.0596387295197733,0.0323719632018963,0.0699604866000883,0.0398891819350068,0.0589368614163519,0.10799917315244,0.0645462057706564,0.0557831446884706,0.0982738432911418,0.0553034373508932,0.0542101198970601,0.0924644954689594,0.0832479892852623,0.0901608957191293,0.0678143292447372,0.0858521235980689,0,0.118865438037975,0.15845336952145,0,0,0 | |||
|gostat_on_MCL_coexpression=GO:0005391;sodium:potassium-exchanging ATPase activity;0.000649603968083954;11931,11928!GO:0043492;ATPase activity, coupled to movement of substances;0.000649603968083954;11931,19300,11928!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000649603968083954;11931,19300,11928!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000649603968083954;11931,19300,11928!GO:0015399;primary active transmembrane transporter activity;0.000649603968083954;11931,19300,11928!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000649603968083954;11931,19300,11928!GO:0042623;ATPase activity, coupled;0.00299468280554583;11931,19300,11928!GO:0016887;ATPase activity;0.00406725087011969;11931,19300,11928!GO:0022857;transmembrane transporter activity;0.00489032804989519;11931,19300,11928,20532!GO:0022804;active transmembrane transporter activity;0.00489032804989519;11931,19300,11928!GO:0015662;ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;0.00489032804989519;11931,11928!GO:0016323;basolateral plasma membrane;0.00489032804989519;11931,11928!GO:0003869;4-nitrophenylphosphatase activity;0.00489032804989519;11928!GO:0031944;negative regulation of glucocorticoid metabolic process;0.00489032804989519;11928!GO:0003812;alternative-complement-pathway C3/C5 convertase activity;0.00489032804989519;14962!GO:0031947;negative regulation of glucocorticoid biosynthetic process;0.00489032804989519;11928!GO:0050104;L-gulonate 3-dehydrogenase activity;0.00489032804989519;68631!GO:0045989;positive regulation of striated muscle contraction;0.00489032804989519;11928!GO:0005890;sodium:potassium-exchanging ATPase complex;0.00489032804989519;11928!GO:0031402;sodium ion binding;0.00540356830941047;11931,11928!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00540356830941047;11931,11928!GO:0016787;hydrolase activity;0.00665296331702059;11931,19300,11928,20532,14962!GO:0017111;nucleoside-triphosphatase activity;0.00665296331702059;11931,19300,11928!GO:0016462;pyrophosphatase activity;0.00665296331702059;11931,19300,11928!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;0.00665296331702059;11931,19300,11928!GO:0031946;regulation of glucocorticoid biosynthetic process;0.00665296331702059;11928!GO:0006942;regulation of striated muscle contraction;0.00665296331702059;11928!GO:0016817;hydrolase activity, acting on acid anhydrides;0.00665296331702059;11931,19300,11928!GO:0030955;potassium ion binding;0.00719419230784296;11931,11928!GO:0006814;sodium ion transport;0.00720758775445428;11931,11928!GO:0051240;positive regulation of multicellular organismal process;0.00760633875252806;11928,14962!GO:0030641;cellular hydrogen ion homeostasis;0.00844369105956371;11928!GO:0031943;regulation of glucocorticoid metabolic process;0.00844369105956371;11928!GO:0006813;potassium ion transport;0.0117900740447466;11931,11928!GO:0006704;glucocorticoid biosynthetic process;0.0122164455235837;11928!GO:0045823;positive regulation of heart contraction;0.0122164455235837;11928!GO:0004556;alpha-amylase activity;0.0122164455235837;20532!GO:0045933;positive regulation of muscle contraction;0.0122164455235837;11928!GO:0031420;alkali metal ion binding;0.013695949110629;11931,11928!GO:0045822;negative regulation of heart contraction;0.0139240775993345;11928!GO:0019218;regulation of steroid metabolic process;0.014437015586575;11928!GO:0015991;ATP hydrolysis coupled proton transport;0.014437015586575;11928!GO:0030004;cellular monovalent inorganic cation homeostasis;0.014437015586575;11928!GO:0016160;amylase activity;0.014437015586575;20532!GO:0055067;monovalent inorganic cation homeostasis;0.014437015586575;11928!GO:0015988;energy coupled proton transport, against electrochemical gradient;0.0161376681274488;11928!GO:0008211;glucocorticoid metabolic process;0.0177651960227553;11928!GO:0006957;complement activation, alternative pathway;0.0193241698064379;14962!GO:0002026;regulation of the force of heart contraction;0.0245945883898245;11928!GO:0051239;regulation of multicellular organismal process;0.0258274784993673;11928,14962!GO:0015672;monovalent inorganic cation transport;0.0267549287020553;11931,11928!GO:0019216;regulation of lipid metabolic process;0.033833195127419;11928!GO:0030317;sperm motility;0.0366749634372288;11928!GO:0006810;transport;0.0425450358553478;11931,19300,11928,20532!GO:0030001;metal ion transport;0.0449090202084987;11931,11928!GO:0051234;establishment of localization;0.0451118381541869;11931,19300,11928,20532!GO:0042383;sarcolemma;0.0454074163261384;11928!GO:0051241;negative regulation of multicellular organismal process;0.0454261965387048;11928!GO:0006941;striated muscle contraction;0.0454261965387048;11928!GO:0042493;response to drug;0.0462005525431601;11928!GO:0006937;regulation of muscle contraction;0.049958755556072;11928! | |||
|ontology_enrichment_celltype=CL:0002563!1.01e-08!9;CL:0002251!1.01e-08!9;CL:0000239!2.70e-07!6;CL:0000677!2.70e-07!6;CL:0000212!2.70e-07!6;CL:0000584!2.70e-07!6;CL:0000066!6.26e-07!25 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0000160!3.73e-24!31;UBERON:0005409!4.75e-19!47;UBERON:0000344!2.38e-14!15;UBERON:0001242!1.45e-12!13;UBERON:0000060!1.45e-12!13;UBERON:0001262!1.45e-12!13;UBERON:0004786!1.45e-12!13;UBERON:0004923!1.56e-10!24;UBERON:0004119!4.67e-10!118;UBERON:0000925!4.67e-10!118;UBERON:0006595!4.67e-10!118;UBERON:0001007!2.91e-09!116;UBERON:0001555!2.91e-09!116;UBERON:0007026!2.91e-09!116;UBERON:0003350!1.01e-08!9;UBERON:0004808!1.01e-08!9;UBERON:0001277!1.01e-08!9;UBERON:0004921!2.99e-08!114 | |||
|tfbs_overrepresentation_for_novel_motifs=0.224466,0.284621,0.204219,0.25808,0.391122,0.743234,0.346405,0.51055,0.0719629,0.646925,0.308886,0.336042,0.237599,0.357027,0.419678,0,0.530547,0.118546,0.814719,0.100162,0.176628,0.837419,0.356242,0.388504,0.603782,1.75954,0.203385,0.287195,0.915208,0.145734,0.275529,0.624931,0.373899,0.397142,0.135203,0.61925,0.111136,0.885722,0.322338,0.581324,0.384293,0.279796,1.08698,0.136236,0.486712,0.24907,0.457618,0.300372,2.04341,0.156829,0.514446,0.404841,0.321327,0.759566,0.776306,0.363247,0.163199,0.325117,0.190698,0.36147,1.47398,0.413233,0.569343,0.504093,0.974413,0.541429,0.908031,1.25063,0.60172,1.10561,1.05857,0.246154,0.351968,0.808562,0.181606,0.0433214,0.702638,0.447339,0.590017,1.61198,0.0707051,1.34858,1.05972,0.227715,0.69807,0.250675,0.0697055,0.611818,0.462057,1.41118,0.975915,0.702809,0.636995,0.401201,0.315787,1.5019,0.503836,0.639644,0.457849,0.842735,0.358446,0.624668,0.742871,0.514993,0.514023,0.76508,0.569344,0.804983,0.539826,0.177945,0.62491,0.744577,1.02113,0.313258,0.982794,1.25018,0.342134,0.26114,0.53175,0.108794,0.813766,0.484912,0.382687,0.446521,1.03573,0.593478,0.353461,1.52534,0.906557,0.807921,0.726634,0.252176,0.877862,0.375176,1.0039,5.29617,0.231086,0.280962,0.955897,1.77738,1.3796,0.91261,0.393303,0.634793,0.508066,0.280171,1.16467,1.73788,0.657796,0.394117,0.3445,0.500318,0.761071,0.29706,0.374365,0.839715,0.405736,0.440483,0.222538,0.652913,2.21508,0.697256,0.593895,0.620756,0.50503,0.367885,0.110426,0.33468,0.238727 | |||
}} |
Latest revision as of 15:26, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr10:69388232..69388250,+ | p2@Ank3 |
Mm9::chr12:85958276..85958369,- | p1@Abcd4 |
Mm9::chr14:58017323..58017346,- | p1@Cryl1 |
Mm9::chr15:80019562..80019612,+ | p@chr15:80019562..80019612 + |
Mm9::chr15:80019614..80019631,+ | p@chr15:80019614..80019631 + |
Mm9::chr16:21868045..21868054,+ | p@chr16:21868045..21868054 + |
Mm9::chr17:34999406..34999417,- | p4@Cfb |
Mm9::chr17:85427687..85427744,+ | p1@Slc3a1 |
Mm9::chr17:85432956..85432975,+ | p@chr17:85432956..85432975 + |
Mm9::chr1:166388476..166388494,- | p1@Atp1b1 |
Mm9::chr3:101408578..101408612,- | p1@Atp1a1 |
Mm9::chr3:96633992..96634038,+ | p1@Pdzk1 |
Mm9::chr3:96634046..96634062,+ | p2@Pdzk1 |
Mm9::chr7:54051031..54051092,- | p1@Hps5 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005391 | sodium:potassium-exchanging ATPase activity | 0.000649603968083954 |
GO:0043492 | ATPase activity, coupled to movement of substances | 0.000649603968083954 |
GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | 0.000649603968083954 |
GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.000649603968083954 |
GO:0015399 | primary active transmembrane transporter activity | 0.000649603968083954 |
GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.000649603968083954 |
GO:0042623 | ATPase activity, coupled | 0.00299468280554583 |
GO:0016887 | ATPase activity | 0.00406725087011969 |
GO:0022857 | transmembrane transporter activity | 0.00489032804989519 |
GO:0022804 | active transmembrane transporter activity | 0.00489032804989519 |
GO:0015662 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | 0.00489032804989519 |
GO:0016323 | basolateral plasma membrane | 0.00489032804989519 |
GO:0003869 | 4-nitrophenylphosphatase activity | 0.00489032804989519 |
GO:0031944 | negative regulation of glucocorticoid metabolic process | 0.00489032804989519 |
GO:0003812 | alternative-complement-pathway C3/C5 convertase activity | 0.00489032804989519 |
GO:0031947 | negative regulation of glucocorticoid biosynthetic process | 0.00489032804989519 |
GO:0050104 | L-gulonate 3-dehydrogenase activity | 0.00489032804989519 |
GO:0045989 | positive regulation of striated muscle contraction | 0.00489032804989519 |
GO:0005890 | sodium:potassium-exchanging ATPase complex | 0.00489032804989519 |
GO:0031402 | sodium ion binding | 0.00540356830941047 |
GO:0042625 | ATPase activity, coupled to transmembrane movement of ions | 0.00540356830941047 |
GO:0016787 | hydrolase activity | 0.00665296331702059 |
GO:0017111 | nucleoside-triphosphatase activity | 0.00665296331702059 |
GO:0016462 | pyrophosphatase activity | 0.00665296331702059 |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.00665296331702059 |
GO:0031946 | regulation of glucocorticoid biosynthetic process | 0.00665296331702059 |
GO:0006942 | regulation of striated muscle contraction | 0.00665296331702059 |
GO:0016817 | hydrolase activity, acting on acid anhydrides | 0.00665296331702059 |
GO:0030955 | potassium ion binding | 0.00719419230784296 |
GO:0006814 | sodium ion transport | 0.00720758775445428 |
GO:0051240 | positive regulation of multicellular organismal process | 0.00760633875252806 |
GO:0030641 | cellular hydrogen ion homeostasis | 0.00844369105956371 |
GO:0031943 | regulation of glucocorticoid metabolic process | 0.00844369105956371 |
GO:0006813 | potassium ion transport | 0.0117900740447466 |
GO:0006704 | glucocorticoid biosynthetic process | 0.0122164455235837 |
GO:0045823 | positive regulation of heart contraction | 0.0122164455235837 |
GO:0004556 | alpha-amylase activity | 0.0122164455235837 |
GO:0045933 | positive regulation of muscle contraction | 0.0122164455235837 |
GO:0031420 | alkali metal ion binding | 0.013695949110629 |
GO:0045822 | negative regulation of heart contraction | 0.0139240775993345 |
GO:0019218 | regulation of steroid metabolic process | 0.014437015586575 |
GO:0015991 | ATP hydrolysis coupled proton transport | 0.014437015586575 |
GO:0030004 | cellular monovalent inorganic cation homeostasis | 0.014437015586575 |
GO:0016160 | amylase activity | 0.014437015586575 |
GO:0055067 | monovalent inorganic cation homeostasis | 0.014437015586575 |
GO:0015988 | energy coupled proton transport, against electrochemical gradient | 0.0161376681274488 |
GO:0008211 | glucocorticoid metabolic process | 0.0177651960227553 |
GO:0006957 | complement activation, alternative pathway | 0.0193241698064379 |
GO:0002026 | regulation of the force of heart contraction | 0.0245945883898245 |
GO:0051239 | regulation of multicellular organismal process | 0.0258274784993673 |
GO:0015672 | monovalent inorganic cation transport | 0.0267549287020553 |
GO:0019216 | regulation of lipid metabolic process | 0.033833195127419 |
GO:0030317 | sperm motility | 0.0366749634372288 |
GO:0006810 | transport | 0.0425450358553478 |
GO:0030001 | metal ion transport | 0.0449090202084987 |
GO:0051234 | establishment of localization | 0.0451118381541869 |
GO:0042383 | sarcolemma | 0.0454074163261384 |
GO:0051241 | negative regulation of multicellular organismal process | 0.0454261965387048 |
GO:0006941 | striated muscle contraction | 0.0454261965387048 |
GO:0042493 | response to drug | 0.0462005525431601 |
GO:0006937 | regulation of muscle contraction | 0.049958755556072 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
intestinal epithelial cell | 1.01e-08 | 9 |
epithelial cell of alimentary canal | 1.01e-08 | 9 |
brush border epithelial cell | 2.70e-07 | 6 |
gut absorptive cell | 2.70e-07 | 6 |
absorptive cell | 2.70e-07 | 6 |
enterocyte | 2.70e-07 | 6 |
epithelial cell | 6.26e-07 | 25 |
Ontology term | p-value | n |
---|---|---|
intestine | 3.73e-24 | 31 |
gastrointestinal system | 4.75e-19 | 47 |
mucosa | 2.38e-14 | 15 |
intestinal mucosa | 1.45e-12 | 13 |
anatomical wall | 1.45e-12 | 13 |
wall of intestine | 1.45e-12 | 13 |
gastrointestinal system mucosa | 1.45e-12 | 13 |
organ component layer | 1.56e-10 | 24 |
endoderm-derived structure | 4.67e-10 | 118 |
endoderm | 4.67e-10 | 118 |
presumptive endoderm | 4.67e-10 | 118 |
digestive system | 2.91e-09 | 116 |
digestive tract | 2.91e-09 | 116 |
primitive gut | 2.91e-09 | 116 |
epithelium of mucosa | 1.01e-08 | 9 |
gastrointestinal system epithelium | 1.01e-08 | 9 |
intestinal epithelium | 1.01e-08 | 9 |
subdivision of digestive tract | 2.99e-08 | 114 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.178528 |
MA0004.1 | 0.717031 |
MA0006.1 | 0.412095 |
MA0007.1 | 0.246385 |
MA0009.1 | 0.649874 |
MA0014.1 | 0.37055 |
MA0017.1 | 1.43837 |
MA0019.1 | 0.480432 |
MA0024.1 | 0.608636 |
MA0025.1 | 0.873493 |
MA0027.1 | 2.275 |
MA0028.1 | 0.138956 |
MA0029.1 | 0.588275 |
MA0030.1 | 0.594419 |
MA0031.1 | 0.561217 |
MA0038.1 | 0.992094 |
MA0040.1 | 0.661716 |
MA0041.1 | 0.198922 |
MA0042.1 | 0.189008 |
MA0043.1 | 0.74191 |
MA0046.1 | 0.683926 |
MA0048.1 | 0.84922 |
MA0050.1 | 0.290354 |
MA0051.1 | 0.388883 |
MA0052.1 | 0.669354 |
MA0055.1 | 1.23886 |
MA0056.1 | 0 |
MA0057.1 | 0.489127 |
MA0058.1 | 0.541281 |
MA0059.1 | 0.19314 |
MA0060.1 | 0.586951 |
MA0061.1 | 0.32765 |
MA0063.1 | 0 |
MA0066.1 | 0.970926 |
MA0067.1 | 0.981551 |
MA0068.1 | 1.17375 |
MA0069.1 | 0.669676 |
MA0070.1 | 0.660488 |
MA0071.1 | 0.289658 |
MA0072.1 | 0.652465 |
MA0073.1 | 0.0195439 |
MA0074.1 | 1.61724 |
MA0076.1 | 0.491745 |
MA0077.1 | 1.52827 |
MA0078.1 | 0.418168 |
MA0081.1 | 0.210747 |
MA0083.1 | 0.741151 |
MA0084.1 | 1.30392 |
MA0087.1 | 0.699999 |
MA0088.1 | 0.171343 |
MA0089.1 | 0 |
MA0090.1 | 1.2186 |
MA0091.1 | 0.269175 |
MA0092.1 | 0.231323 |
MA0093.1 | 0.444403 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.330364 |
MA0101.1 | 0.57968 |
MA0103.1 | 0.157724 |
MA0105.1 | 0.684733 |
MA0106.1 | 0.425111 |
MA0107.1 | 1.45792 |
MA0108.2 | 0.50131 |
MA0109.1 | 0 |
MA0111.1 | 0.679612 |
MA0113.1 | 0.400008 |
MA0114.1 | 2.87734 |
MA0115.1 | 0.744589 |
MA0116.1 | 0.8172 |
MA0117.1 | 0.713754 |
MA0119.1 | 0.200349 |
MA0122.1 | 0.732707 |
MA0124.1 | 0.929684 |
MA0125.1 | 0.857794 |
MA0130.1 | 0 |
MA0131.1 | 0.476296 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 3.0506 |
MA0136.1 | 0.357464 |
MA0139.1 | 0.231431 |
MA0140.1 | 0.330266 |
MA0141.1 | 0.511953 |
MA0142.1 | 0.547747 |
MA0143.1 | 1.06535 |
MA0144.1 | 1.11784 |
MA0145.1 | 0.614688 |
MA0146.1 | 0.458458 |
MA0147.1 | 0.107632 |
MA0148.1 | 0.271704 |
MA0149.1 | 1.11452 |
MA0062.2 | 0.177386 |
MA0035.2 | 0.888731 |
MA0039.2 | 0.945584 |
MA0138.2 | 0.469076 |
MA0002.2 | 0.235791 |
MA0137.2 | 0.506794 |
MA0104.2 | 0.0740839 |
MA0047.2 | 0.380343 |
MA0112.2 | 0.0731504 |
MA0065.2 | 0.371748 |
MA0150.1 | 0.246295 |
MA0151.1 | 0 |
MA0152.1 | 0.380437 |
MA0153.1 | 0.792819 |
MA0154.1 | 0.837005 |
MA0155.1 | 0.423059 |
MA0156.1 | 0.163042 |
MA0157.1 | 0.518122 |
MA0158.1 | 0 |
MA0159.1 | 0.365914 |
MA0160.1 | 1.37966 |
MA0161.1 | 0 |
MA0162.1 | 0.353984 |
MA0163.1 | 0.094989 |
MA0164.1 | 0.940888 |
MA0080.2 | 0.467794 |
MA0018.2 | 0.366212 |
MA0099.2 | 0.463355 |
MA0079.2 | 0.227458 |
MA0102.2 | 1.35579 |
MA0258.1 | 1.04836 |
MA0259.1 | 0.678628 |
MA0442.1 | 0 |