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{{CL
{{CL
|id=CL:0002138
|alt_id=CL:1000421
|name=endothelial cell of lymphatic vessel
|namespace=cell
|def="A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions." [GOC:tfm, PMID:17846148]
|xref=BTO:0004167;;FMA:68458
|is_a=CL:0002139
|synonym="lymphatic endothelial cell" EXACT []
|comment=
|comment=
|alt_id=CL:1000421
|disjoint_from=
|union_of=
|created_by=tmeehan
|created_by=tmeehan
|obo_creation_date=2010-08-24T02:05:28Z
|def="A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions." [GOC:tfm, PMID:17846148]
|subset=
|derives_from=
|derives_from=
|develops_from=CL:0005022
|develops_from=CL:0005022
|disjoint_from=
|has_quality=
|has_quality=
|id=CL:0002138
|is_a=CL:0002139
|is_obsolete=
|located_in=
|located_in=
|name=endothelial cell of lymphatic vessel
|namespace=cell
|obo_creation_date=2010-08-24T02:05:28Z
|part_of=UBERON:0001473
|part_of=UBERON:0001473
|preceded_by=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl-to-uberon.owl;;IAO:0000412 http://purl.obolibrary.org/obo/cl.owl
|is_obsolete=
|subset=
|preceded_by=
|synonym="lymphatic endothelial cell" EXACT []
|union_of=
|xref=BTO:0004167;;FMA:68458
}}
}}

Revision as of 10:24, 12 September 2014

Name:endothelial cell of lymphatic vessel
Namespace:cell
Definition:"A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions." [GOC:tfm, PMID:17846148]
Xrefs:
links:

BTO:0004167

FMA:68458
Synonyms: "lymphatic endothelial cell" EXACT []
Alt_id: CL:1000421
Created by:tmeehan
Creation date:2010-08-24T02:05:28Z


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0002139(endothelial cell of vascular tree)
develops_from:CL:0005022(vascular lymphangioblast)
part_of:UBERON:0001473(lymphatic vessel)



Children


derives from:FF:0000049 (human lymphatic endothelial cell sample)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

  • 11236-116D3 (Endothelial Cells - Lymphatic, donor1)
  • 11317-117D3 (Endothelial Cells - Lymphatic, donor2)
  • 11393-118C7 (Endothelial Cells - Lymphatic, donor3)
  • 12260-130A1 (Lymphatic Endothelial cells response to VEGFC)
  • 12261-130A2 (Lymphatic Endothelial cells response to VEGFC)
  • 12262-130A3 (Lymphatic Endothelial cells response to VEGFC)
  • 12263-130A4 (Lymphatic Endothelial cells response to VEGFC)
  • 12264-130A5 (Lymphatic Endothelial cells response to VEGFC)
  • 12265-130A6 (Lymphatic Endothelial cells response to VEGFC)
  • 12266-130A7 (Lymphatic Endothelial cells response to VEGFC)

... further results Mouse (Mus musculus)

  • 11236-116D3 (Endothelial Cells - Lymphatic, donor1)
  • 11317-117D3 (Endothelial Cells - Lymphatic, donor2)
  • 11393-118C7 (Endothelial Cells - Lymphatic, donor3)
  • 12260-130A1 (Lymphatic Endothelial cells response to VEGFC)
  • 12261-130A2 (Lymphatic Endothelial cells response to VEGFC)
  • 12262-130A3 (Lymphatic Endothelial cells response to VEGFC)
  • 12263-130A4 (Lymphatic Endothelial cells response to VEGFC)
  • 12264-130A5 (Lymphatic Endothelial cells response to VEGFC)
  • 12265-130A6 (Lymphatic Endothelial cells response to VEGFC)
  • 12266-130A7 (Lymphatic Endothelial cells response to VEGFC)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0002138 (endothelial cell of lymphatic vessel), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
1.07e-135FFCP PHASE1:Hg19::chr9:13432964..13432971,-#_6a50ef612b11f34865aa7617761330dep@chr9:13432964..13432971, -
1.07e-135FFCP PHASE2:Hg19::chr9:13432964..13432971,-#_6a50ef612b11f34865aa7617761330dep@chr9:13432964..13432971, -
5.17e-105FFCP PHASE2:Hg19::chr1:65344872..65344880,-#_0a19f25d2835be6c2b813548f81d498bp15@JAK1
5.17e-105FFCP PHASE1:Hg19::chr1:65344872..65344880,-#_0a19f25d2835be6c2b813548f81d498bp15@JAK1
5.07e-102FFCP PHASE2:Hg19::chr3:30560368..30560379,+#_adaf34333ea191f83a77ea6e8a5f154cp@chr3:30560368..30560379, +
5.07e-102FFCP PHASE1:Hg19::chr3:30560368..30560379,+#_adaf34333ea191f83a77ea6e8a5f154cp@chr3:30560368..30560379, +
1.86e-98FFCP PHASE1:Hg19::chr17:28534912..28534942,-#_1e2f0b5d6fde11d90227c52c29689c6ep@chr17:28534912..28534942, -
1.86e-98FFCP PHASE2:Hg19::chr17:28534912..28534942,-#_1e2f0b5d6fde11d90227c52c29689c6ep@chr17:28534912..28534942, -
3.73e-91FFCP PHASE1:Hg19::chr2:56149881..56149899,-#_34b2bc2f78cf7478249568729581de40p14@EFEMP1
3.73e-91FFCP PHASE2:Hg19::chr2:56149881..56149899,-#_34b2bc2f78cf7478249568729581de40p14@EFEMP1
3.34e-87FFCP PHASE2:Hg19::chr19:48613876..48613886,-#_dfc93749e38457b10cd015e104e48b38p7@PLA2G4C
3.34e-87FFCP PHASE1:Hg19::chr19:48613876..48613886,-#_dfc93749e38457b10cd015e104e48b38p7@PLA2G4C
1.6e-85FFCP PHASE2:Hg19::chr6:74848034..74848043,+#_314e794efd543701f32203309de9667fp@chr6:74848034..74848043, +
1.6e-85FFCP PHASE1:Hg19::chr6:74848034..74848043,+#_314e794efd543701f32203309de9667fp@chr6:74848034..74848043, +
1.48e-75FFCP PHASE1:Hg19::chr6:5054373..5054392,-#_88ebd24f2060744a68f32e03f7c5efd8p1@AK126470
1.48e-75FFCP PHASE2:Hg19::chr6:5054373..5054392,-#_88ebd24f2060744a68f32e03f7c5efd8p1@AK126470
2.17e-75FFCP PHASE2:Hg19::chr7:79998842..79998855,+#_7cd6e5889553d267f07087ebdf0dd83ap25@CD36
2.17e-75FFCP PHASE1:Hg19::chr7:79998842..79998855,+#_7cd6e5889553d267f07087ebdf0dd83ap25@CD36
2.63e-75FFCP PHASE2:Hg19::chr3:145968441..145968451,-#_1264963ac8172556a327bc0ccb87dcfbp17@PLSCR4
2.63e-75FFCP PHASE1:Hg19::chr3:145968441..145968451,-#_1264963ac8172556a327bc0ccb87dcfbp17@PLSCR4
3.19e-75FFCP PHASE1:Hg19::chr2:33661536..33661549,+#_c4016d9c2c454929578033d5d92ca89dp17@RASGRP3
3.19e-75FFCP PHASE2:Hg19::chr2:33661536..33661549,+#_c4016d9c2c454929578033d5d92ca89dp17@RASGRP3
3.86e-75FFCP PHASE2:Hg19::chr9:13446440..13446456,+#_81f48dddef093d29f73b5c8deb1346d2p2@ENST00000428006
3.86e-75FFCP PHASE1:Hg19::chr9:13446440..13446456,+#_81f48dddef093d29f73b5c8deb1346d2p2@ENST00000428006
2.58e-74FFCP PHASE1:Hg19::chr12:46807404..46807413,+#_b406f06a4d7bf12c326e0a3d8688139dp@chr12:46807404..46807413, +
2.58e-74FFCP PHASE2:Hg19::chr17:28534879..28534889,-#_b406f06a4d7bf12c326e0a3d8688139dp@chr17:28534879..28534889, -
2.58e-74FFCP PHASE1:Hg19::chr17:28534879..28534889,-#_b406f06a4d7bf12c326e0a3d8688139dp@chr17:28534879..28534889, -
2.58e-74FFCP PHASE2:Hg19::chr12:46807404..46807413,+#_b406f06a4d7bf12c326e0a3d8688139dp@chr12:46807404..46807413, +
4.26e-74FFCP PHASE1:Hg19::chr7:79998905..79998917,+#_aad76360566331f74c87a4900f0f9c19p26@CD36
4.26e-74FFCP PHASE2:Hg19::chr7:79998905..79998917,+#_aad76360566331f74c87a4900f0f9c19p26@CD36
1.77e-72FFCP PHASE2:Hg19::chr8:30300216..30300245,+#_874aaae6d45b5578d068698fd73e1c98p10@RBPMS
1.77e-72FFCP PHASE1:Hg19::chr8:30300216..30300245,+#_874aaae6d45b5578d068698fd73e1c98p10@RBPMS
2.83e-66FFCP PHASE1:Hg19::chr11:108794408..108794422,+#_eedf83058fa1f6b19b670b13ff2ef189p@chr11:108794408..108794422, +
2.83e-66FFCP PHASE2:Hg19::chr17:75873825..75873826,+#_eedf83058fa1f6b19b670b13ff2ef189p@chr17:75873825..75873826, +
2.83e-66FFCP PHASE2:Hg19::chr11:108794429..108794441,+#_eedf83058fa1f6b19b670b13ff2ef189p@chr11:108794429..108794441, +
2.83e-66FFCP PHASE1:Hg19::chr11:108794429..108794441,+#_eedf83058fa1f6b19b670b13ff2ef189p@chr11:108794429..108794441, +
2.83e-66FFCP PHASE2:Hg19::chr4:114238344..114238353,+#_eedf83058fa1f6b19b670b13ff2ef189p58@ANK2
2.83e-66FFCP PHASE1:Hg19::chr17:75873825..75873826,+#_eedf83058fa1f6b19b670b13ff2ef189p@chr17:75873825..75873826, +
2.83e-66FFCP PHASE1:Hg19::chr4:114238344..114238353,+#_eedf83058fa1f6b19b670b13ff2ef189p58@ANK2
2.83e-66FFCP PHASE2:Hg19::chr2:33661526..33661535,+#_eedf83058fa1f6b19b670b13ff2ef189p23@RASGRP3
2.83e-66FFCP PHASE2:Hg19::chr1:66723029..66723041,+#_eedf83058fa1f6b19b670b13ff2ef189p54@PDE4B
2.83e-66FFCP PHASE1:Hg19::chr2:33661526..33661535,+#_eedf83058fa1f6b19b670b13ff2ef189p23@RASGRP3
2.83e-66FFCP PHASE2:Hg19::chr11:108794408..108794422,+#_eedf83058fa1f6b19b670b13ff2ef189p@chr11:108794408..108794422, +
2.83e-66FFCP PHASE1:Hg19::chr1:66723029..66723041,+#_eedf83058fa1f6b19b670b13ff2ef189p54@PDE4B
1.5e-63FFCP PHASE2:Hg19::chr4:189881560..189881604,-#_4e4f70a0c76af9869c860a39000ce8f9p@chr4:189881560..189881604, -
1.5e-63FFCP PHASE1:Hg19::chr4:189881560..189881604,-#_4e4f70a0c76af9869c860a39000ce8f9p@chr4:189881560..189881604, -
2.87e-63FFCP PHASE2:Hg19::chr4:90857427..90857438,+#_9399607e63c1e5abac3fcc27f4913728p@chr4:90857427..90857438, +
2.87e-63FFCP PHASE1:Hg19::chr4:90857427..90857438,+#_9399607e63c1e5abac3fcc27f4913728p@chr4:90857427..90857438, +
3.26e-63FFCP PHASE1:Hg19::chr10:4823152..4823165,-#_c13d8ac99576df3915c102d06cf4f844p@chr10:4823152..4823165, -
3.26e-63FFCP PHASE2:Hg19::chr10:4823152..4823165,-#_c13d8ac99576df3915c102d06cf4f844p@chr10:4823152..4823165, -
7.06e-63FFCP PHASE1:Hg19::chr6:49534004..49534016,+#_4ce8b32198f7b8dda8bbe33978a70f7cp@chr6:49534004..49534016, +
7.06e-63FFCP PHASE2:Hg19::chr6:49534004..49534016,+#_4ce8b32198f7b8dda8bbe33978a70f7cp@chr6:49534004..49534016, +
1.53e-62FFCP PHASE2:Hg19::chr12:96841308..96841312,+#_b6aa45d92ebd1a3a0eaf7236f2ca4b09p@chr12:96841308..96841312, +
1.53e-62FFCP PHASE1:Hg19::chr12:96841308..96841312,+#_b6aa45d92ebd1a3a0eaf7236f2ca4b09p@chr12:96841308..96841312, +
8.15e-60FFCP PHASE2:Hg19::chr1:43917566..43917577,-#_bfdf603b9078241f5068e880892f58d7p6@HYI
8.15e-60FFCP PHASE1:Hg19::chr1:43917566..43917577,-#_bfdf603b9078241f5068e880892f58d7p6@HYI
9.96e-60FFCP PHASE2:Hg19::chr3:34262215..34262222,+#_6a49df615b094c3aa18fc61df806ffa6p@chr3:34262215..34262222, +
9.96e-60FFCP PHASE1:Hg19::chr3:34262215..34262222,+#_6a49df615b094c3aa18fc61df806ffa6p@chr3:34262215..34262222, +
1.22e-59FFCP PHASE2:Hg19::chr18:54339814..54339822,+#_cbb45bab7ed266519c39e5cc23b765efp7@WDR7
1.22e-59FFCP PHASE1:Hg19::chr18:54339814..54339822,+#_cbb45bab7ed266519c39e5cc23b765efp7@WDR7
1.82e-59FFCP PHASE2:Hg19::chr7:10196589..10196595,-#_70e71fb9a77d0791411bc1aa7bb92f3cp@chr7:10196589..10196595, -
1.82e-59FFCP PHASE1:Hg19::chr7:10196589..10196595,-#_70e71fb9a77d0791411bc1aa7bb92f3cp@chr7:10196589..10196595, -
2.22e-59FFCP PHASE2:Hg19::chr2:62705562..62705579,+#_a82d37ea6e7ecf660d44be9c14a43e39p@chr2:62705562..62705579, +
2.22e-59FFCP PHASE1:Hg19::chr2:62705562..62705579,+#_a82d37ea6e7ecf660d44be9c14a43e39p@chr2:62705562..62705579, +
8.76e-59FFCP PHASE1:Hg19::chr4:90856951..90856962,+#_150335af5ef57524b606fe096fae6d9bp@chr4:90856951..90856962, +
8.76e-59FFCP PHASE2:Hg19::chr12:71031281..71031292,-#_150335af5ef57524b606fe096fae6d9bp12@PTPRB
8.76e-59FFCP PHASE1:Hg19::chr12:71031281..71031292,-#_150335af5ef57524b606fe096fae6d9bp12@PTPRB
8.76e-59FFCP PHASE2:Hg19::chr4:90856951..90856962,+#_150335af5ef57524b606fe096fae6d9bp@chr4:90856951..90856962, +
2.07e-53FFCP PHASE1:Hg19::chr12:105882068..105882076,+#_da02fc7cf42ff89a292ad15d0b9419c1p@chr12:105882068..105882076, +
2.07e-53FFCP PHASE2:Hg19::chr12:105882068..105882076,+#_da02fc7cf42ff89a292ad15d0b9419c1p@chr12:105882068..105882076, +
2.7e-53FFCP PHASE2:Hg19::chr8:6459787..6459796,+#_bbd95a1f90e00bb408ed4e7b0d839d2fp@chr8:6459787..6459796, +
2.7e-53FFCP PHASE1:Hg19::chr8:6459787..6459796,+#_bbd95a1f90e00bb408ed4e7b0d839d2fp@chr8:6459787..6459796, +
8.47e-53FFCP PHASE2:Hg19::chr4:38057595..38057624,-#_9fa2542fd387e01d310bfbc26000fe52p@chr4:38057595..38057624, -
8.47e-53FFCP PHASE1:Hg19::chr4:38057595..38057624,-#_9fa2542fd387e01d310bfbc26000fe52p@chr4:38057595..38057624, -
5.43e-52FFCP PHASE2:Hg19::chr3:194868639..194868654,+#_6ca45daba0b4cde6c6c5bc45a1957e33p1@ENST00000426468
5.43e-52FFCP PHASE1:Hg19::chr3:194868639..194868654,+#_6ca45daba0b4cde6c6c5bc45a1957e33p1@ENST00000426468
5.37e-50FFCP PHASE2:Hg19::chr8:16425014..16425019,-#_dd6f69b253c28f9d598a31ab03f70440p13@MSR1
5.37e-50FFCP PHASE1:Hg19::chr8:16425014..16425019,-#_dd6f69b253c28f9d598a31ab03f70440p13@MSR1
1.05e-49FFCP PHASE2:Hg19::chr6:168195978..168195989,+#_6d69dd135a110c8348655d22eabec825p3@LOC441179
1.05e-49FFCP PHASE1:Hg19::chr6:168195978..168195989,+#_6d69dd135a110c8348655d22eabec825p3@LOC441179
1.46e-49FFCP PHASE1:Hg19::chr2:27487913..27487933,-#_cd7d173396a5eb58a2d6b84109c78a6cp@chr2:27487913..27487933, -
1.46e-49FFCP PHASE2:Hg19::chr2:27487913..27487933,-#_cd7d173396a5eb58a2d6b84109c78a6cp@chr2:27487913..27487933, -
2.21e-49FFCP PHASE2:Hg19::chr8:6420777..6420779,-#_f45fbb29336114aed0f95710d16e5f36p5@ANGPT2
2.21e-49FFCP PHASE1:Hg19::chr8:6420777..6420779,-#_f45fbb29336114aed0f95710d16e5f36p5@ANGPT2
9.56e-49FFCP PHASE2:Hg19::chr10:94590895..94590905,+#_60be643f122e5b9282f3fa355f3a4b9dp8@EXOC6
9.56e-49FFCP PHASE1:Hg19::chr10:94590895..94590905,+#_60be643f122e5b9282f3fa355f3a4b9dp8@EXOC6
4.56e-48FFCP PHASE2:Hg19::chr8:16425043..16425061,-#_32caff43d24cd79b501a9d2646a18a0ep5@MSR1
4.56e-48FFCP PHASE1:Hg19::chr8:16425043..16425061,-#_32caff43d24cd79b501a9d2646a18a0ep5@MSR1
4.82e-46FFCP PHASE2:Hg19::chr17:79426425..79426444,+#_30da1b9b4085eef394b755e227fe2ef6p@chr17:79426425..79426444, +
4.82e-46FFCP PHASE1:Hg19::chr17:79426425..79426444,+#_30da1b9b4085eef394b755e227fe2ef6p@chr17:79426425..79426444, +
9.71e-46FFCP PHASE2:Hg19::chr11:57543275..57543296,+#_0822a7d76c4e0dd2831a20ed41f33fedp@chr11:57543275..57543296, +
9.71e-46FFCP PHASE1:Hg19::chr11:57543275..57543296,+#_0822a7d76c4e0dd2831a20ed41f33fedp@chr11:57543275..57543296, +
1.36e-44FFCP PHASE2:Hg19::chr19:45226133..45226157,-#_295a947e720cc4b3c304acc2436e3c63p@chr19:45226133..45226157, -
1.36e-44FFCP PHASE1:Hg19::chr19:45226133..45226157,-#_295a947e720cc4b3c304acc2436e3c63p@chr19:45226133..45226157, -
3.19e-44FFCP PHASE2:Hg19::chr3:159570877..159570888,+#_524c3825ffe5ae32410add477f8d5798p43@SCHIP1
3.19e-44FFCP PHASE1:Hg19::chr3:159570877..159570888,+#_524c3825ffe5ae32410add477f8d5798p43@SCHIP1
6.49e-44FFCP PHASE1:Hg19::chr12:71031220..71031229,-#_7d1e82751c0e0611b5daf94c0ac44b71p10@PTPRB
6.49e-44FFCP PHASE2:Hg19::chr12:71031220..71031229,-#_7d1e82751c0e0611b5daf94c0ac44b71p10@PTPRB
8.09e-44FFCP PHASE1:Hg19::chr7:79998864..79998896,+#_3b3f0b7a5219585a7c29a83a5c24fb9dp12@CD36
8.09e-44FFCP PHASE2:Hg19::chr7:79998864..79998896,+#_3b3f0b7a5219585a7c29a83a5c24fb9dp12@CD36

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