UBERON:0002103: Difference between revisions
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|has_quality= | |has_quality= | ||
|id=UBERON:0002103 | |id=UBERON:0002103 | ||
|is_a=UBERON:0002101;;UBERON:0004709 | |is_a=UBERON:0002101 ;;UBERON:0004709 | ||
|is_obsolete= | |is_obsolete= | ||
|located_in= | |located_in= | ||
|name=hindlimb | |name=hindlimb | ||
|namespace= | |namespace=FANTOM | ||
|obo_creation_date= | |obo_creation_date= | ||
|part_of=UBERON:0000154;;UBERON:0010709 | |part_of=UBERON:0010709;;UBERON:0000154;;UBERON:0010709 | ||
|preceded_by= | |preceded_by= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Lower limb, which connects the pes with the pelvic girdle.[AAO]" xsd:string | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/uberon.owl;;UBPROP:0000001 "Lower limb, which connects the pes with the pelvic girdle.[AAO]" xsd:string | ||
Latest revision as of 17:26, 12 September 2014
| Name: | hindlimb | ||
|---|---|---|---|
| Namespace: | FANTOM | ||
| Definition: | "A (free) limb that is connected to a pelvic girdle region. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pelvic girdle and its parts." [UBERONREF:0000003, Wikipedia:Lower_limb] | ||
| Xrefs: |
| ||
| Synonyms: |
"free lower limb" EXACT [FMA:24879, UBERONREF:0000003] "hind limb" EXACT [] "hindlimb" EXACT [] "inferior member" EXACT [] "lower extremity" RELATED [] "lower limb" EXACT [] "membrum inferius" EXACT [FMA:7184, FMA:TA] "membrum inferius" RELATED LATIN [Wikipedia:Lower_limb] "pelvic appendage" RELATED [] | ||
| Comments: | AO notes: note that this corresponds to FMA:'free lower limb' (a limb segment), NOT 'lower limb'. Both MA and FMA consider shoulder (and shoulder bones) part of upper limb. Note that AAO class probably refers to skeleton | ||
| Alt_id: | UBERON:FMA_7184-MA_0000026-MIAA_0000395-XAO_0003031 | ||
| Subset: | uberon_slim |
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Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
| is_a: | UBERON:0002101(limb),UBERON:0004709(pelvic appendage) |
|---|---|
| develops_from: | UBERON:0005418(hindlimb bud) |
| part_of: | UBERON:0010709(pelvic complex),UBERON:0000154(posterior region of body),UBERON:0010709(pelvic complex) |
Children
| part of: | UBERON:0000376 (hindlimb stylopod),UBERON:0000978 (leg),UBERON:0001377 (quadriceps femoris),UBERON:0001441 (hindlimb skeleton),UBERON:0002387 (foot),UBERON:0003464 (hindlimb bone),UBERON:0003532 (hindlimb skin),UBERON:0003589 (hindlimb connective tissue),UBERON:0003608 (hindlimb long bone),UBERON:0003663 (hindlimb muscle),UBERON:0003823 (hindlimb zeugopod),UBERON:0003840 (hindlimb joint),UBERON:0003860 (hindlimb mesenchyme),UBERON:0004482 (musculature of lower limb),UBERON:0008784 (lower limb segment),UBERON:0010885 (hindlimb cartilage element),UBERON:0010886 (hindlimb bone pre-cartilage condensation),UBERON:0015022 (hindlimb endochondral element) |
|---|
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10264-104D3
- 10267-104D6
- 10281-104F2
- 10282-104F3 (skeletal muscle - soleus muscle, donor1)
- 10285-104F6
- 10292-104G4 (achilles tendon, donor2)
- 10295-104G7 (cruciate ligament, donor2)
- 10309-104I3
- 10310-104I4
- 10313-104I7
... further results Mouse (Mus musculus)
- 10264-104D3
- 10267-104D6
- 10281-104F2
- 10282-104F3 (skeletal muscle - soleus muscle, donor1)
- 10285-104F6
- 10292-104G4 (achilles tendon, donor2)
- 10295-104G7 (cruciate ligament, donor2)
- 10309-104I3
- 10310-104I4
- 10313-104I7
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002103 (hindlimb), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data
| P-value | FFCP | Short description |
|---|---|---|
| 5.42e-195 | FFCP PHASE2:Hg19::chr11:3691037..3691040,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr11:3691037..3691040, + |
| 5.42e-195 | FFCP PHASE1:Hg19::chr4:85166508..85166512,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr4:85166508..85166512, + |
| 5.42e-195 | FFCP PHASE1:Hg19::chr7:128483294..128483304,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr7:128483294..128483304, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr10:79759687..79759690,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr10:79759687..79759690, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr22:25535147..25535150,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr22:25535147..25535150, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr7:128483294..128483304,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr7:128483294..128483304, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr4:85166508..85166512,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr4:85166508..85166512, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr2:179396370..179396375,-#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr2:179396370..179396375, - |
| 5.42e-195 | FFCP PHASE1:Hg19::chr10:97176812..97176813,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr10:97176812..97176813, + |
| 5.42e-195 | FFCP PHASE1:Hg19::chr2:76859417..76859418,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr2:76859417..76859418, + |
| 5.42e-195 | FFCP PHASE1:Hg19::chr11:3691037..3691040,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr11:3691037..3691040, + |
| 5.42e-195 | FFCP PHASE1:Hg19::chr4:186423235..186423240,-#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr4:186423235..186423240, - |
| 5.42e-195 | FFCP PHASE1:Hg19::chr22:25535147..25535150,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr22:25535147..25535150, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr4:186423235..186423240,-#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr4:186423235..186423240, - |
| 5.42e-195 | FFCP PHASE1:Hg19::chr10:79759687..79759690,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr10:79759687..79759690, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr2:76859417..76859418,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr2:76859417..76859418, + |
| 5.42e-195 | FFCP PHASE2:Hg19::chr10:97176812..97176813,+#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr10:97176812..97176813, + |
| 5.42e-195 | FFCP PHASE1:Hg19::chr2:179396370..179396375,-#_fb8b33c4f8432875a0a880c5f8ff2a15 | p@chr2:179396370..179396375, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr22:36000901..36000903,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr22:36000901..36000903, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:152553958..152553964,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152553958..152553964, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr5:175125123..175125125,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:175125123..175125125, + |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:168102721..168102729,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p77@XIRP2 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:152499727..152499734,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152499727..152499734, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr8:144542829..144542857,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr8:144542829..144542857, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:168104926..168104927,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p108@XIRP2 |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:168105362..168105368,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p46@XIRP2 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:152520248..152520253,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152520248..152520253, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:179399371..179399376,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:179399371..179399376, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr8:144542829..144542857,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr8:144542829..144542857, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr5:172318159..172318160,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:172318159..172318160, + |
| 9.37e-99 | FFCP PHASE2:Hg19::chr13:114067922..114067931,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr13:114067922..114067931, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr5:117747577..117747580,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:117747577..117747580, + |
| 9.37e-99 | FFCP PHASE1:Hg19::chr15:51060095..51060101,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr15:51060095..51060101, + |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:152525581..152525588,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152525581..152525588, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr5:175125123..175125125,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:175125123..175125125, + |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:168105987..168105994,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p54@XIRP2 |
| 9.37e-99 | FFCP PHASE1:Hg19::chr13:51335579..51335582,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr13:51335579..51335582, + |
| 9.37e-99 | FFCP PHASE1:Hg19::chr1:145478051..145478060,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr1:145478051..145478060, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:152534468..152534476,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152534468..152534476, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:179514306..179514308,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:179514306..179514308, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:168104676..168104679,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p104@XIRP2 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr1:119487319..119487331,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr1:119487319..119487331, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:152499727..152499734,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152499727..152499734, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:64069328..64069334,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p7@FLJ36848 |
| 9.37e-99 | FFCP PHASE1:Hg19::chr6:33716557..33716600,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr6:33716557..33716600, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr5:172318159..172318160,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:172318159..172318160, + |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:152553958..152553964,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152553958..152553964, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr7:66800928..66800936,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p1@ENST00000430244, p1@uc003tvu.2 |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:168104926..168104927,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p108@XIRP2 |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:152520248..152520253,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152520248..152520253, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr15:51060095..51060101,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr15:51060095..51060101, + |
| 9.37e-99 | FFCP PHASE2:Hg19::chr6:33716557..33716600,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr6:33716557..33716600, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:168102721..168102729,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p77@XIRP2 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:168106638..168106641,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p93@XIRP2 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr13:51335579..51335582,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr13:51335579..51335582, + |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:179399371..179399376,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:179399371..179399376, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr22:36000901..36000903,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr22:36000901..36000903, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr5:137206180..137206187,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:137206180..137206187, + |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:64069328..64069334,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p7@FLJ36848 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr7:66800928..66800936,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p1@ENST00000430244, p1@uc003tvu.2 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:168105362..168105368,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p46@XIRP2 |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:152534468..152534476,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152534468..152534476, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:152525581..152525588,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:152525581..152525588, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr13:114067922..114067931,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr13:114067922..114067931, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr3:188070178..188070183,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr3:188070178..188070183, + |
| 9.37e-99 | FFCP PHASE2:Hg19::chr5:137206180..137206187,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:137206180..137206187, + |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:168105987..168105994,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p54@XIRP2 |
| 9.37e-99 | FFCP PHASE1:Hg19::chr1:119487319..119487331,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr1:119487319..119487331, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr1:145478051..145478060,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr1:145478051..145478060, - |
| 9.37e-99 | FFCP PHASE1:Hg19::chr5:117747577..117747580,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr5:117747577..117747580, + |
| 9.37e-99 | FFCP PHASE1:Hg19::chr2:168106638..168106641,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p93@XIRP2 |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:179514306..179514308,-#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr2:179514306..179514308, - |
| 9.37e-99 | FFCP PHASE2:Hg19::chr3:188070178..188070183,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p@chr3:188070178..188070183, + |
| 9.37e-99 | FFCP PHASE2:Hg19::chr2:168104676..168104679,+#_35a9ab3cde91cfbad26108dbe4e5e80b | p104@XIRP2 |
| 2.55e-98 | FFCP PHASE1:Hg19::chr21:47769234..47769239,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr21:47769234..47769239, + |
| 2.55e-98 | FFCP PHASE1:Hg19::chr10:29918007..29918031,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr10:29918007..29918031, - |
| 2.55e-98 | FFCP PHASE1:Hg19::chr2:152590465..152590472,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr2:152590465..152590472, - |
| 2.55e-98 | FFCP PHASE2:Hg19::chr5:95180155..95180172,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr5:95180155..95180172, + |
| 2.55e-98 | FFCP PHASE2:Hg19::chr12:122884464..122884467,-#_a73d950e1c28a6057dc81039c2fc4879 | p38@CLIP1 |
| 2.55e-98 | FFCP PHASE2:Hg19::chr2:168102459..168102468,+#_a73d950e1c28a6057dc81039c2fc4879 | p73@XIRP2 |
| 2.55e-98 | FFCP PHASE1:Hg19::chr2:179656442..179656451,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr2:179656442..179656451, - |
| 2.55e-98 | FFCP PHASE1:Hg19::chr3:69168368..69168389,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr3:69168368..69168389, - |
| 2.55e-98 | FFCP PHASE1:Hg19::chr12:122884464..122884467,-#_a73d950e1c28a6057dc81039c2fc4879 | p38@CLIP1 |
| 2.55e-98 | FFCP PHASE2:Hg19::chr2:152566311..152566321,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr2:152566311..152566321, - |
| 2.55e-98 | FFCP PHASE2:Hg19::chr10:97037060..97037066,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr10:97037060..97037066, - |
| 2.55e-98 | FFCP PHASE2:Hg19::chr2:179656442..179656451,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr2:179656442..179656451, - |
| 2.55e-98 | FFCP PHASE2:Hg19::chr12:102079632..102079647,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr12:102079632..102079647, - |
| 2.55e-98 | FFCP PHASE1:Hg19::chr3:35732964..35732965,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr3:35732964..35732965, + |
| 2.55e-98 | FFCP PHASE1:Hg19::chr12:69653866..69653876,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr12:69653866..69653876, + |
| 2.55e-98 | FFCP PHASE1:Hg19::chr2:29398214..29398229,+#_a73d950e1c28a6057dc81039c2fc4879 | p27@CLIP4 |
| 2.55e-98 | FFCP PHASE2:Hg19::chr22:26299595..26299605,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr22:26299595..26299605, + |
| 2.55e-98 | FFCP PHASE2:Hg19::chr10:29918007..29918031,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr10:29918007..29918031, - |
| 2.55e-98 | FFCP PHASE1:Hg19::chr18:8608021..8608050,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr18:8608021..8608050, + |
| 2.55e-98 | FFCP PHASE2:Hg19::chr3:69168368..69168389,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr3:69168368..69168389, - |
| 2.55e-98 | FFCP PHASE2:Hg19::chr3:35732964..35732965,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr3:35732964..35732965, + |
| 2.55e-98 | FFCP PHASE1:Hg19::chr12:102079632..102079647,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr12:102079632..102079647, - |
| 2.55e-98 | FFCP PHASE1:Hg19::chr6:125535391..125535409,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr6:125535391..125535409, + |
| 2.55e-98 | FFCP PHASE2:Hg19::chr2:29398214..29398229,+#_a73d950e1c28a6057dc81039c2fc4879 | p27@CLIP4 |
| 2.55e-98 | FFCP PHASE2:Hg19::chr2:152590465..152590472,-#_a73d950e1c28a6057dc81039c2fc4879 | p@chr2:152590465..152590472, - |
| 2.55e-98 | FFCP PHASE1:Hg19::chr3:46924232..46924241,+#_a73d950e1c28a6057dc81039c2fc4879 | p@chr3:46924232..46924241, + |
Property "Property value" (as page type) with input value "UBPROP:0000001 "Lower limb, which connects the pes with the pelvic girdle.[AAO]" xsd:string" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
