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{{Coexpression_clusters
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|full_id=C518_sacrococcigeal_Prostate_Mesenchymal_Fibroblast_tridermal_Hair_placenta
|id=C518
|ontology_enrichment_celltype=CL:0000055!7.03e-22!180;CL:0000057!2.96e-14!75
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000481!7.42e-24!347;UBERON:0000475!2.61e-20!365;UBERON:0000468!1.09e-19!659;UBERON:0003102!2.75e-15!95;UBERON:0003104!1.83e-13!238;UBERON:0009142!1.83e-13!238;UBERON:0000467!6.08e-13!625;UBERON:0000480!1.19e-12!626;UBERON:0000922!1.57e-12!612;UBERON:0000064!2.20e-12!219;UBERON:0000062!5.06e-12!511;UBERON:0005256!3.44e-11!143;UBERON:0004119!6.69e-11!169;UBERON:0000925!6.69e-11!169;UBERON:0006595!6.69e-11!169;UBERON:0002050!8.15e-11!605;UBERON:0005423!8.15e-11!605;UBERON:0000923!1.65e-10!604;UBERON:0005291!1.65e-10!604;UBERON:0006598!1.65e-10!604;UBERON:0002532!1.65e-10!604;UBERON:0002100!2.47e-10!216;UBERON:0000119!4.13e-10!312;UBERON:0001007!6.31e-10!155;UBERON:0001555!6.31e-10!155;UBERON:0007026!6.31e-10!155;UBERON:0000914!6.91e-10!83;UBERON:0002329!6.91e-10!83;UBERON:0003077!6.91e-10!83;UBERON:0003059!6.91e-10!83;UBERON:0007282!6.91e-10!83;UBERON:0009618!6.91e-10!83;UBERON:0007285!6.91e-10!83;UBERON:0000483!1.68e-09!309;UBERON:0004923!6.86e-09!57;UBERON:0000486!1.95e-08!82;UBERON:0000924!4.65e-08!173;UBERON:0006601!4.65e-08!173;UBERON:0004290!5.14e-08!70;UBERON:0004121!5.80e-08!169;UBERON:0000477!7.83e-08!286;UBERON:0001444!1.08e-07!48;UBERON:0002199!2.35e-07!45;UBERON:0002416!2.35e-07!45;UBERON:0000077!8.09e-07!130;UBERON:0000063!9.62e-07!97
}}

Latest revision as of 11:24, 17 September 2013


Full id: C518_sacrococcigeal_Prostate_Mesenchymal_Fibroblast_tridermal_Hair_placenta



Phase1 CAGE Peaks

Hg19::chr22:45898754..45898771,+p1@FBLN1
Hg19::chr22:45928975..45928998,+p5@FBLN1
Hg19::chr22:45929702..45929734,+p3@FBLN1
Hg19::chr22:45938067..45938094,+p@chr22:45938067..45938094
+
Hg19::chr22:45938119..45938132,+p@chr22:45938119..45938132
+
Hg19::chr22:45939285..45939335,+p@chr22:45939285..45939335
+
Hg19::chr22:45939339..45939352,+p@chr22:45939339..45939352
+
Hg19::chr22:45939357..45939377,+p@chr22:45939357..45939377
+
Hg19::chr22:45942994..45943026,+p@chr22:45942994..45943026
+
Hg19::chr22:45943028..45943051,+p@chr22:45943028..45943051
+
Hg19::chr22:45944499..45944509,+p@chr22:45944499..45944509
+
Hg19::chr22:45944516..45944530,+p@chr22:45944516..45944530
+
Hg19::chr22:45946433..45946447,+p@chr22:45946433..45946447
+
Hg19::chr22:45958815..45958838,+p@chr22:45958815..45958838
+
Hg19::chr22:45958840..45958880,+p@chr22:45958840..45958880
+
Hg19::chr22:45958878..45958908,-p@chr22:45958878..45958908
-
Hg19::chr22:45958896..45958922,+p@chr22:45958896..45958922
+
Hg19::chr22:45996721..45996735,+p2@FBLN1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fibroblast1.57e-1376
skin fibroblast2.84e-0723
Uber Anatomy
Ontology termp-valuen
surface structure3.34e-1199
organ component layer4.17e-0966
multi-tissue structure8.07e-09342
multi-cellular organism2.83e-08656
endoderm-derived structure8.82e-08160
endoderm8.82e-08160
presumptive endoderm8.82e-08160
larynx3.12e-079
digestive system3.86e-07145
digestive tract3.86e-07145
primitive gut3.86e-07145
integument6.18e-0746
integumental system6.18e-0746


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.217628
MA0004.10.207008
MA0006.10.334079
MA0007.11.07281
MA0009.10.600198
MA0014.10.606715
MA0017.10.125342
MA0019.10.322194
MA0024.10.50459
MA0025.10.725013
MA0027.12.18072
MA0028.11.19395
MA0029.10.522011
MA0030.10.511665
MA0031.10.454061
MA0038.10.285594
MA0040.10.527306
MA0041.10.220669
MA0042.10.197306
MA0043.10.60049
MA0046.10.590147
MA0048.11.89858
MA0050.10.197941
MA0051.10.282227
MA0052.10.530811
MA0055.13.58978
MA0056.10
MA0057.10.493527
MA0058.10.435867
MA0059.10.433767
MA0060.10.0444001
MA0061.10.321845
MA0063.10
MA0066.10.285934
MA0067.10.900956
MA0068.10.0967272
MA0069.11.43296
MA0070.10.576293
MA0071.10.255111
MA0072.10.572162
MA0073.10.0078903
MA0074.10.281628
MA0076.10.902204
MA0077.10.565087
MA0078.10.363755
MA0081.10.434032
MA0083.10.607144
MA0084.11.08294
MA0087.10.569916
MA0088.10.0658118
MA0089.10
MA0090.10.94245
MA0091.10.208918
MA0092.10.53622
MA0093.10.338722
MA0095.10
MA0098.10
MA0100.10.804369
MA0101.10.105632
MA0103.10.658605
MA0105.11.30924
MA0106.10.319
MA0107.10.0664936
MA0108.20.451357
MA0109.10
MA0111.10.980329
MA0113.10.332535
MA0114.11.79357
MA0115.10.827474
MA0116.10.0681676
MA0117.10.635078
MA0119.15.78474
MA0122.10.659244
MA0124.10.787807
MA0125.10.708116
MA0130.10
MA0131.10.988046
MA0132.10
MA0133.10
MA0135.10.628343
MA0136.10.291242
MA0139.11.68229
MA0140.10.704517
MA0141.10.139313
MA0142.10.426146
MA0143.10.885144
MA0144.10.209582
MA0145.10.512167
MA0146.10.368533
MA0147.10.525775
MA0148.10.225411
MA0149.10.245595
MA0062.20.56657
MA0035.20.252505
MA0039.20.0112889
MA0138.20.364793
MA0002.20.0398531
MA0137.20.11518
MA0104.20.168935
MA0047.20.309071
MA0112.20.160258
MA0065.20.32973
MA0150.10.926004
MA0151.10
MA0152.10.258148
MA0153.10.692238
MA0154.12.08217
MA0155.10.446769
MA0156.10.116546
MA0157.10.402372
MA0158.10
MA0159.11.35392
MA0160.10.236884
MA0161.10
MA0162.10.06468
MA0163.11.31481
MA0164.10.342871
MA0080.20.103778
MA0018.20.320136
MA0099.20.716923
MA0079.20.0344262
MA0102.21.11935
MA0258.10.762782
MA0259.10.0740439
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.