MCL coexpression mm9:247: Difference between revisions
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{{MCL_coexpression_mm9 | 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7312724536,-0.0372002197989992|gostat_on_MCL_coexpression=GO:0030118;clathrin coat;0.00103007122298327;12757,232910,11764!GO:0006810;transport;0.00103007122298327;14325,11972,59005,76308,114143,232910,228545,24045,17775,11764,12757!GO:0030132;clathrin coat of coated pit;0.00103007122298327;12757,232910!GO:0051234;establishment of localization;0.00103007122298327;14325,11972,59005,76308,114143,232910,228545,24045,17775,11764,12757!GO:0008565;protein transporter activity;0.00103007122298327;76308,12757,232910,11764!GO:0031090;organelle membrane;0.00103007122298327;57813,24045,625249,114143,12757,232910!GO:0030117;membrane coat;0.00108040588994423;12757,232910,11764!GO:0048475;coated membrane;0.00108040588994423;12757,232910,11764!GO:0046907;intracellular transport;0.00110542519164257;24045,59005,76308,12757,232910,11764!GO:0051179;localization;0.00140422280644445;14325,11972,59005,76308,114143,232910,228545,24045,17775,11764,12757!GO:0015031;protein transport;0.00153093705585413;228545,24045,76308,12757,232910,11764!GO:0006886;intracellular protein transport;0.00161306751112645;24045,76308,12757,232910,11764!GO:0045184;establishment of protein localization;0.00171093958241412;228545,24045,76308,12757,232910,11764!GO:0030125;clathrin vesicle coat;0.00213343846402819;12757,232910!GO:0008104;protein localization;0.00213343846402819;228545,24045,76308,12757,232910,11764!GO:0051649;establishment of cellular localization;0.00213343846402819;24045,59005,76308,12757,232910,11764!GO:0051641;cellular localization;0.00213343846402819;24045,59005,76308,12757,232910,11764!GO:0033036;macromolecule localization;0.00213343846402819;228545,24045,76308,12757,232910,11764!GO:0030665;clathrin coated vesicle membrane;0.00213343846402819;12757,232910!GO:0012505;endomembrane system;0.00441195157246126;24045,625249,12757,232910!GO:0008553;hydrogen-exporting ATPase activity, phosphorylative mechanism;0.00441195157246126;11972,114143!GO:0030119;AP-type membrane coat adaptor complex;0.00441195157246126;232910,11764!GO:0030120;vesicle coat;0.00441195157246126;12757,232910!GO:0030131;clathrin adaptor complex;0.00441195157246126;232910,11764!GO:0006461;protein complex assembly;0.00470957795315152;12757,232910,11764!GO:0030662;coated vesicle membrane;0.00478895219045733;12757,232910!GO:0022892;substrate-specific transporter activity;0.00480224779721872;11972,76308,114143,12757,232910,11764!GO:0044431;Golgi apparatus part;0.00493250926918007;24045,12757,11764!GO:0044446;intracellular organelle part;0.00537977021139587;228545,57813,24045,116748,625249,114143,12757,232910,11764!GO:0044422;organelle part;0.00537977021139587;228545,57813,24045,116748,625249,114143,12757,232910,11764!GO:0005905;coated pit;0.00537977021139587;12757,232910!GO:0015985;energy coupled proton transport, down electrochemical gradient;0.00537977021139587;11972,114143!GO:0015986;ATP synthesis coupled proton transport;0.00537977021139587;11972,114143!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;0.0066582076626911;11972,114143!GO:0006754;ATP biosynthetic process;0.0066582076626911;11972,114143!GO:0006753;nucleoside phosphate metabolic process;0.0066582076626911;11972,114143!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;0.00666359935002401;11972,114143!GO:0016469;proton-transporting two-sector ATPase complex;0.00666359935002401;11972,114143!GO:0030659;cytoplasmic vesicle membrane;0.00684869670245069;12757,232910!GO:0046034;ATP metabolic process;0.00733965127932895;11972,114143!GO:0016192;vesicle-mediated transport;0.00733965127932895;59005,12757,232910,11764!GO:0005683;snRNP U7;0.00733965127932895;116748!GO:0030128;clathrin coat of endocytic vesicle;0.00733965127932895;232910!GO:0030669;clathrin-coated endocytic vesicle membrane;0.00733965127932895;232910!GO:0047066;phospholipid-hydroperoxide glutathione peroxidase activity;0.00733965127932895;625249!GO:0030122;AP-2 adaptor complex;0.00733965127932895;232910!GO:0030666;endocytic vesicle membrane;0.00733965127932895;232910!GO:0045334;clathrin-coated endocytic vesicle;0.00733965127932895;232910!GO:0009201;ribonucleoside triphosphate biosynthetic process;0.00733965127932895;11972,114143!GO:0009145;purine nucleoside triphosphate biosynthetic process;0.00733965127932895;11972,114143!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;0.00733965127932895;11972,114143!GO:0019829;cation-transporting ATPase activity;0.00784930021274493;11972,114143!GO:0009142;nucleoside triphosphate biosynthetic process;0.00803046940300961;11972,114143!GO:0009205;purine ribonucleoside triphosphate metabolic process;0.0080621608790061;11972,114143!GO:0044433;cytoplasmic vesicle part;0.0080621608790061;12757,232910!GO:0009199;ribonucleoside triphosphate metabolic process;0.0082424065135637;11972,114143!GO:0006119;oxidative phosphorylation;0.00827727366333041;11972,114143!GO:0009144;purine nucleoside triphosphate metabolic process;0.00827727366333041;11972,114143!GO:0015992;proton transport;0.00878214655816941;11972,114143!GO:0006752;group transfer coenzyme metabolic process;0.00896171348440969;11972,114143!GO:0012506;vesicle membrane;0.00932030532341178;12757,232910!GO:0009141;nucleoside triphosphate metabolic process;0.00932030532341178;11972,114143!GO:0009152;purine ribonucleotide biosynthetic process;0.0094993236673797;11972,114143!GO:0006818;hydrogen transport;0.009678152953148;11972,114143!GO:0015662;ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;0.0101896217294751;11972,114143!GO:0009260;ribonucleotide biosynthetic process;0.0103682295299337;11972,114143!GO:0008334;histone mRNA metabolic process;0.0104502479417977;116748!GO:0006398;histone mRNA 3'-end processing;0.0104502479417977;116748!GO:0009150;purine ribonucleotide metabolic process;0.0109027702625417;11972,114143!GO:0006164;purine nucleotide biosynthetic process;0.0110805182261044;11972,114143!GO:0000139;Golgi membrane;0.0122874565081795;24045,12757!GO:0016043;cellular component organization and biogenesis;0.0122937969140547;228545,24045,59005,76308,625249,12757,232910,11764!GO:0009259;ribonucleotide metabolic process;0.0122937969140547;11972,114143!GO:0006163;purine nucleotide metabolic process;0.0133460554113547;11972,114143!GO:0030136;clathrin-coated vesicle;0.0133460554113547;12757,232910!GO:0004797;thymidine kinase activity;0.0140176496158612;57813!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.0155181757503771;11972,114143!GO:0009108;coenzyme biosynthetic process;0.0160676712181081;11972,114143!GO:0031410;cytoplasmic vesicle;0.0167030811733568;12757,232910,11764!GO:0030135;coated vesicle;0.0171744129955214;12757,232910!GO:0031982;vesicle;0.0174130932340225;12757,232910,11764!GO:0015078;hydrogen ion transmembrane transporter activity;0.0182903938285974;11972,114143!GO:0065003;macromolecular complex assembly;0.0195806801547763;12757,232910,11764!GO:0051188;cofactor biosynthetic process;0.0195806801547763;11972,114143!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.0195806801547763;11972,114143!GO:0019136;deoxynucleoside kinase activity;0.0203864894195307;57813!GO:0017069;snRNA binding;0.0203864894195307;116748!GO:0033176;proton-transporting V-type ATPase complex;0.023635378738937;114143!GO:0007032;endosome organization and biogenesis;0.023635378738937;228545!GO:0016471;vacuolar proton-transporting V-type ATPase complex;0.023635378738937;114143!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.025666442978984;11972,114143!GO:0043492;ATPase activity, coupled to movement of substances;0.025666442978984;11972,114143!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0258180711699936;11972,114143!GO:0015030;Cajal body;0.0258370423680537;116748!GO:0015991;ATP hydrolysis coupled proton transport;0.0258370423680537;114143!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0258370423680537;12757!GO:0022607;cellular component assembly;0.0268907328992126;12757,232910,11764!GO:0009165;nucleotide biosynthetic process;0.0270004433233914;11972,114143!GO:0012510;trans-Golgi network transport vesicle membrane;0.0283314092552593;12757!GO:0015988;energy coupled proton transport, against electrochemical gradient;0.0283314092552593;114143!GO:0015399;primary active transmembrane transporter activity;0.0284489783883669;11972,114143!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0284489783883669;11972,114143!GO:0022890;inorganic cation transmembrane transporter activity;0.029453131230454;11972,114143!GO:0004602;glutathione peroxidase activity;0.030630183309856;625249!GO:0010038;response to metal ion;0.0333731215676864;67675!GO:0008199;ferric iron binding;0.0333731215676864;14325!GO:0030532;small nuclear ribonucleoprotein complex;0.0353561526702033;116748!GO:0030660;Golgi-associated vesicle membrane;0.0353561526702033;12757!GO:0030658;transport vesicle membrane;0.0353561526702033;12757!GO:0019206;nucleoside kinase activity;0.0353561526702033;57813!GO:0030140;trans-Golgi network transport vesicle;0.0382019566560164;12757!GO:0017111;nucleoside-triphosphatase activity;0.0383366047387109;11972,76308,114143!GO:0006732;coenzyme metabolic process;0.0388458469411079;11972,114143!GO:0030139;endocytic vesicle;0.0399241084609958;232910!GO:0010035;response to inorganic substance;0.0399241084609958;67675!GO:0006812;cation transport;0.0399695485103797;14325,11972,114143!GO:0005768;endosome;0.0402453259276258;228545,114143!GO:0016462;pyrophosphatase activity;0.0411696170722686;11972,76308,114143!GO:0044444;cytoplasmic part;0.0411696170722686;228545,57813,24045,625249,114143,12757,232910,11764!GO:0031124;mRNA 3'-end processing;0.0411696170722686;116748!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;0.0411696170722686;11972,76308,114143!GO:0016817;hydrolase activity, acting on acid anhydrides;0.0411696170722686;11972,76308,114143!GO:0009117;nucleotide metabolic process;0.0451322533584478;11972,114143!GO:0006888;ER to Golgi vesicle-mediated transport;0.0451322533584478;59005!GO:0005774;vacuolar membrane;0.0451322533584478;114143!GO:0016023;cytoplasmic membrane-bound vesicle;0.0468035196720562;12757,232910!GO:0051186;cofactor metabolic process;0.0468035196720562;11972,114143!GO:0031123;RNA 3'-end processing;0.0468035196720562;116748!GO:0005773;vacuole;0.0480836459269845;228545,114143!GO:0030133;transport vesicle;0.0483825743086711;12757!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.0483825743086711;11972,114143!GO:0031988;membrane-bound vesicle;0.0483825743086711;12757,232910!|ontology_enrichment_celltype=CL:0000055!1.63e-22!49;CL:0000221!3.67e-20!44;CL:0000133!3.67e-20!44;CL:0002319!4.03e-20!43;CL:0000393!1.58e-16!39;CL:0000211!1.58e-16!39;CL:0002371!3.05e-16!118;CL:0000548!1.16e-14!115;CL:0000255!1.16e-14!115;CL:0000723!2.03e-14!91;CL:0000048!2.03e-14!91;CL:0000540!2.81e-14!33;CL:0000047!2.81e-14!33;CL:0000031!2.81e-14!33;CL:0000404!2.81e-14!33;CL:0002321!4.31e-14!70;CL:0000034!1.36e-12!97;CL:0000117!4.78e-12!23;CL:0000337!4.78e-12!23;CL:0000333!7.19e-07!10;CL:0000095!7.19e-07!10;CL:0000243!7.19e-07!10;CL:0000123!7.19e-07!10;CL:0000125!7.19e-07!10;CL:0000030!7.19e-07!10;CL:0000339!7.19e-07!10|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0001016!1.81e-30!75;UBERON:0001017!1.38e-29!73;UBERON:0004121!1.89e-23!95;UBERON:0000924!1.89e-23!95;UBERON:0006601!1.89e-23!95;UBERON:0000073!2.70e-21!54;UBERON:0001049!5.42e-20!52;UBERON:0005068!5.42e-20!52;UBERON:0006241!5.42e-20!52;UBERON:0007135!5.42e-20!52;UBERON:0002346!1.10e-17!64;UBERON:0003075!1.10e-17!64;UBERON:0007284!1.10e-17!64;UBERON:0000955!4.20e-17!47;UBERON:0006238!4.20e-17!47;UBERON:0002616!6.21e-17!46;UBERON:0002020!1.27e-16!34;UBERON:0003080!1.46e-14!40;UBERON:0010371!1.65e-14!73;UBERON:0002780!3.53e-14!39;UBERON:0001890!3.53e-14!39;UBERON:0006240!3.53e-14!39;UBERON:0003528!4.67e-14!29;UBERON:0002791!4.67e-14!29;UBERON:0001893!4.67e-14!29;UBERON:0010314!1.15e-11!92;UBERON:0003056!1.25e-11!49;UBERON:0000956!2.92e-10!21;UBERON:0001869!2.92e-10!21;UBERON:0000203!2.92e-10!21;UBERON:0002619!5.66e-09!17|tfbs_overrepresentation_for_novel_motifs=0.74152,0.142265,0.662873,0.236371,0.181931,0.253392,1.78311,0.701456,0.174976,1.61118,1.07339,0.353689,0.702703,0.774793,0.398921,0,0.242789,0.338711,0.252973,0.239398,0.0314253,0.614819,0.772638,0.179733,1.06019,0.841161,0.232042,0.585756,0.763313,0.569266,0.941675,0.317094,0.333399,0.318136,1.34916,0.117041,0.155054,0.708929,0.263296,1.14566,0.0671228,0.958489,0.170978,0.0183248,1.22659,1.76816,0.553826,0.298674,0.00494366,1.13031,0.230631,0.46489,0.125124,0.430267,0.44481,0.396933,0.271595,1.13767,0.108538,0.787009,0.301892,0.930636,0.815195,0.634224,0.818723,0.700001,0.562061,0.88291,0.808107,0.744997,1.83085,0.168686,1.64326,0.473077,0.50913,1.49422,0.186144,0.181883,0.786958,0.131982,0.170798,1.30906,0.157582,0.448811,0.984767,6.22059,0.317243,0.244615,1.06797,1.03797,0.624114,0.993559,0.326924,0.190478,0.442518,0.102603,0.464079,0.329091,1.66618,0.184302,0.311947,0.31688,0.415858,0.231041,0.230314,3.23445,2.112,0.087018,0.136395,0.888158,0.408259,0.417326,0.313137,1.0907,0.630454,0.065984,1.83892,1.33278,0.243704,0.150167,0.477668,0.208777,0.138324,0.18131,0.679524,0.793204,0.119921,0.860616,2.36035,0.0756537,0.401936,0.0637522,0.534808,0.133513,0.649958,0.0310715,0.0537973,0.0783817,0.605717,1.39723,1.00731,0.566216,0.445833,0.325124,0.22586,0.268482,0.558662,1.35822,0.0546506,2.10664,1.06357,2.60154,0.431571,1.2361,0.82257,0.500669,0.909695,0.429583,0.0499578,0.766477,0.61423,0.376993,0.29213,1.09854,0.223599,0.128895,0.0569897,0.10857,3.09957|tfbs_overrepresentation_jaspar=MA0003.1;1.8759,MA0004.1;3.03297,MA0006.1;1.31921,MA0007.1;0.82717,MA0009.1;0.337492,MA0014.1;6.29301,MA0017.1;0.241082,MA0019.1;0.205515,MA0024.1;0.820639,MA0025.1;0.530879,MA0027.1;1.89129,MA0028.1;6.63563,MA0029.1;0.287662,MA0030.1;0.292547,MA0031.1;0.266391,MA0038.1;0.425709,MA0040.1;0.347276,MA0041.1;0.155958,MA0042.1;0.036061,MA0043.1;0.415031,MA0046.1;0.365786,MA0048.1;1.41666,MA0050.1;0.59417,MA0051.1;0.862788,MA0052.1;0.353618,MA0055.1;0.2045,MA0056.1;0,MA0057.1;0.400394,MA0058.1;4.08724,MA0059.1;0.620066,MA0060.1;5.56512,MA0061.1;0.466178,MA0063.1;0,MA0066.1;0.41007,MA0067.1;0.629308,MA0068.1;0.0146185,MA0069.1;0.353886,MA0070.1;0.346258,MA0071.1;0.0830235,MA0072.1;0.339628,MA0073.1;0.0120521,MA0074.1;0.360358,MA0076.1;8.06312,MA0077.1;0.32285,MA0078.1;0.161775,MA0081.1;0.688174,MA0083.1;0.414379,MA0084.1;0.934141,MA0087.1;0.379309,MA0088.1;2.55794,MA0089.1;0,MA0090.1;0.198563,MA0091.1;0.0722516,MA0092.1;0.439746,MA0093.1;5.36672,MA0095.1;0,MA0098.1;0,MA0100.1;0.701922,MA0101.1;0.646174,MA0103.1;0.258738,MA0105.1;0.92278,MA0106.1;0.498719,MA0107.1;0.75593,MA0108.2;0.629361,MA0109.1;0,MA0111.1;0.467988,MA0113.1;0.149628,MA0114.1;0.0460994,MA0115.1;0.417336,MA0116.1;0.639448,MA0117.1;0.390961,MA0119.1;0.0405474,MA0122.1;0.407133,MA0124.1;0.581749,MA0125.1;0.516802,MA0130.1;0,MA0131.1;2.46035,MA0132.1;0,MA0133.1;0,MA0135.1;0.445266,MA0136.1;0.775995,MA0139.1;1.60281,MA0140.1;0.105959,MA0141.1;0.0297262,MA0142.1;0.255956,MA0143.1;0.159321,MA0144.1;0.468617,MA0145.1;2.04381,MA0146.1;3.5853,MA0147.1;0.509447,MA0148.1;0.0735508,MA0149.1;0.0420811,MA0062.2;5.79247,MA0035.2;0.108338,MA0039.2;4.91635,MA0138.2;0.197313,MA0002.2;0.0696121,MA0137.2;0.5305,MA0104.2;1.39556,MA0047.2;0.136816,MA0112.2;0.714902,MA0065.2;0.254159,MA0150.1;0.219664,MA0151.1;0,MA0152.1;0.424765,MA0153.1;0.459241,MA0154.1;0.448933,MA0155.1;1.34988,MA0156.1;0.807998,MA0157.1;0.233393,MA0158.1;0,MA0159.1;0.0603505,MA0160.1;0.0748272,MA0161.1;0,MA0162.1;4.44727,MA0163.1;0.427523,MA0164.1;0.122585,MA0080.2;0.47059,MA0018.2;0.800068,MA0099.2;0.193216,MA0079.2;1.71659,MA0102.2;0.984244,MA0258.1;0.415286,MA0259.1;0.727482,MA0442.1;0}} | ||
|coexpression_dpi_cluster_scores_mean=0.0601297865718834,-0.0381060150168721,-0.0421366266600367,-0.130697503787271,-0.165105048970359,-0.0773914229680079,-0.0877685378928644,0.0316331711920637,-0.231200838974523,-0.226204399866673,-0.232142212892609,-0.234843448991718,-0.00573425730707628,0.00290228464674319,-0.0457431159286352,-0.0562897140263282,-0.0675579407777328,0.0474493552718107,0.0120035380803718,0.0436809180583622,0.0755692335482015,0.0108280152019571,0.0230674078298679,0.00993033080935993,0.0579215501205415,0.0352285948149038,0.0421361603360257,0.0167092262975502,0.0512822934637367,-0.0132280514045789,0.0690858900205723,0.00728013371726717,0.0438472741071295,-0.489616516864385,-0.153151510944412,-0.110277571993104,-0.15672054157724,0.30213819054859,0.30928148052028,0.236647330005937,0.331031991632903,0.30494452577182,0.294676285160911,0.121576127318323,0.138163513950727,0.10245439114,0.502920320651187,0.325664654775966,0.337062787487854,0.338809383072051,0.258984054405816,0.355022441845464,0.0268723153403313,-0.0481676691422041,-0.0515490851643399,0.180198705905473,0.241305307217499,0.224394651481079,0.26191657640748,0.242844502599325,0.294006471877524,0.35250729204217,0.367656055437447,0.776145199295024,0.803074909430348,0.838464284315296,0.5421449741001,0.581837945922093,0.132798842650053,0.166463025966344,0.151271272080336,0.354036806633186,0.3293123347849,0.138638729002894,0.134216909022256,0.215828268401924,0.266830618626503,0.271152399000147,0.27081132527563,0.233732772636375,0.247526703202761,0.207903831319355,0.370386134690808,0.334363030894858,0.302703286953441,0.220409409300816,0.218481554816519,0.203556301585073,0.171914363824051,0.221898491654379,0.0130074515121002,0.053740591795976,-0.00862545829400993,0.0083904909556724,-0.0384819584973669,-0.0787810052266333,0.0413208807232373,0.116596240172722,0.171274552244475,0.177456598218479,0.0757345827856663,0.0150061325096169,-0.205754772537053,-0.186921536462783,0.0232498957341726,0.0533546642038708,0.0466850622649336,-0.0130684202125486,-0.0680656134174732,0.0165476589153109,0.0031564981545781,0.00917023256670317,0.0225260605998576,0.035898823557812,-0.0339618848642193,0.0362464917885793,0.0528685748588033,-0.0591643104327232,0.0356649811965481,-0.0414300859950595,-0.0305078641424593,-0.0542807121913318,-0.059260430540621,0.0539153062627254,0.0863500793516412,-0.0378944077723259,-0.0223473828394624,0.0519783930972588,0.000111533533216323,0.164318023213326,0.16266751526313,0.133693965944424,0.191007142969345,0.171890592380337,0.190404290643585,0.176918381832715,-0.0370283486008463,0.00187058878314855,0.104716181844748,0.031468822303509,-0.0712130533033538,0.0446700476914398,-0.0099044844462863,-0.0289430743433824,-0.0562655409900119,-0.0360388856518402,0.0150481193701638,-0.00047240664277436,-0.0836102955583978,-0.118862531098135,-0.075903080720355,-0.0102265646505591,-0.113255312023765,-0.0567730060660585,-0.0593730704153249,-0.0709133990416865,-0.0203883070213568,0.0430361408857309,0.0487513798397177,-0.067934390117036,-0.0720052879616528,-0.0626502311089093,-0.0877749319258476,-0.0620828200935892,-0.0723905320345591,-0.0762787691268387,-0.074492921473008,-0.0899055854991597,-0.0919685744076408,-0.0704763514635627,-0.0825805950261043,-0.0443574818604942,-0.0433968684320767,-0.0311118613442059,0.185472810590747,0.0877901543277847,-0.0532248103031275,-0.101133656743292,-0.0860183591675795,-0.116174476811114,-0.117903645438123,-0.0606734225126837,-0.0112275960912012,0.0472524872312962,-0.0154348359169592,0.0485537798074536,0.0438726544914294,0.06294336468607,0.0258171867717436,-0.0963950093917154,-0.0379284838143659,-0.032548257103788,0.0201665505719819,-0.0957938543184466,-0.114045653548632,-0.0971158461151253,-0.067053828442287,-0.073633004236644,-0.0446307012602949,-0.0456839885936534,-0.0212752085089485,-0.000884003053659985,-0.0208664910832456,-0.151480691667884,-0.120864506243101,-0.130149097614873,-0.138558604831583,-0.0957695363978039,-0.0827526972450619,-0.100270070311179,-0.108666441040096,-0.0894037313056832,-0.145015831394564,-0.0361108046504893,-0.0459622930333613,-0.0451184236186847,-0.110077759470953,-0.0211225233885067,0.0293346323427075,-0.0187852936493429,-0.101507340446382,-0.0884381535009935,-0.0889910060704952,-0.0781422321184862,-0.0421918335691685,-0.0194965724911502,-0.0672088744032883,-0.0424445952825374,-0.0201132583144093,0.0205811394949274,0.0497017210968258,0.0316879553085878,0.512664776245491,0.497251905187298,0.04211982437666,0.00175118922567818,0.188082773291708,0.167216973145862,-0.0226361235671626,-0.0045774356109501,0.116095177145135,0.110378728374107,0.0920255052054162,0.100282932928765,0.127285839411786,0.0985249993278593,0.130272328491159,0.137420405589191,0.0847546063593665,0.114215465310049,-0.0374819139651847,0.0585680072739977,-0.0228222218001281,0.00244816702722105,-0.0322051766046437,-0.066150753840406,-0.0349891356170115,-0.0726853541480557,0.0192823651774893,-0.00711980686514328,-0.0286550746270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| |||
| | |||
}} |
Latest revision as of 14:57, 17 September 2013
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0030118 | clathrin coat | 0.00103007122298327 |
GO:0006810 | transport | 0.00103007122298327 |
GO:0030132 | clathrin coat of coated pit | 0.00103007122298327 |
GO:0051234 | establishment of localization | 0.00103007122298327 |
GO:0008565 | protein transporter activity | 0.00103007122298327 |
GO:0031090 | organelle membrane | 0.00103007122298327 |
GO:0030117 | membrane coat | 0.00108040588994423 |
GO:0048475 | coated membrane | 0.00108040588994423 |
GO:0046907 | intracellular transport | 0.00110542519164257 |
GO:0051179 | localization | 0.00140422280644445 |
GO:0015031 | protein transport | 0.00153093705585413 |
GO:0006886 | intracellular protein transport | 0.00161306751112645 |
GO:0045184 | establishment of protein localization | 0.00171093958241412 |
GO:0030125 | clathrin vesicle coat | 0.00213343846402819 |
GO:0008104 | protein localization | 0.00213343846402819 |
GO:0051649 | establishment of cellular localization | 0.00213343846402819 |
GO:0051641 | cellular localization | 0.00213343846402819 |
GO:0033036 | macromolecule localization | 0.00213343846402819 |
GO:0030665 | clathrin coated vesicle membrane | 0.00213343846402819 |
GO:0012505 | endomembrane system | 0.00441195157246126 |
GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism | 0.00441195157246126 |
GO:0030119 | AP-type membrane coat adaptor complex | 0.00441195157246126 |
GO:0030120 | vesicle coat | 0.00441195157246126 |
GO:0030131 | clathrin adaptor complex | 0.00441195157246126 |
GO:0006461 | protein complex assembly | 0.00470957795315152 |
GO:0030662 | coated vesicle membrane | 0.00478895219045733 |
GO:0022892 | substrate-specific transporter activity | 0.00480224779721872 |
GO:0044431 | Golgi apparatus part | 0.00493250926918007 |
GO:0044446 | intracellular organelle part | 0.00537977021139587 |
GO:0044422 | organelle part | 0.00537977021139587 |
GO:0005905 | coated pit | 0.00537977021139587 |
GO:0015985 | energy coupled proton transport, down electrochemical gradient | 0.00537977021139587 |
GO:0015986 | ATP synthesis coupled proton transport | 0.00537977021139587 |
GO:0046933 | hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.0066582076626911 |
GO:0006754 | ATP biosynthetic process | 0.0066582076626911 |
GO:0006753 | nucleoside phosphate metabolic process | 0.0066582076626911 |
GO:0046961 | hydrogen ion transporting ATPase activity, rotational mechanism | 0.00666359935002401 |
GO:0016469 | proton-transporting two-sector ATPase complex | 0.00666359935002401 |
GO:0030659 | cytoplasmic vesicle membrane | 0.00684869670245069 |
GO:0046034 | ATP metabolic process | 0.00733965127932895 |
GO:0016192 | vesicle-mediated transport | 0.00733965127932895 |
GO:0005683 | snRNP U7 | 0.00733965127932895 |
GO:0030128 | clathrin coat of endocytic vesicle | 0.00733965127932895 |
GO:0030669 | clathrin-coated endocytic vesicle membrane | 0.00733965127932895 |
GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity | 0.00733965127932895 |
GO:0030122 | AP-2 adaptor complex | 0.00733965127932895 |
GO:0030666 | endocytic vesicle membrane | 0.00733965127932895 |
GO:0045334 | clathrin-coated endocytic vesicle | 0.00733965127932895 |
GO:0009201 | ribonucleoside triphosphate biosynthetic process | 0.00733965127932895 |
GO:0009145 | purine nucleoside triphosphate biosynthetic process | 0.00733965127932895 |
GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 0.00733965127932895 |
GO:0019829 | cation-transporting ATPase activity | 0.00784930021274493 |
GO:0009142 | nucleoside triphosphate biosynthetic process | 0.00803046940300961 |
GO:0009205 | purine ribonucleoside triphosphate metabolic process | 0.0080621608790061 |
GO:0044433 | cytoplasmic vesicle part | 0.0080621608790061 |
GO:0009199 | ribonucleoside triphosphate metabolic process | 0.0082424065135637 |
GO:0006119 | oxidative phosphorylation | 0.00827727366333041 |
GO:0009144 | purine nucleoside triphosphate metabolic process | 0.00827727366333041 |
GO:0015992 | proton transport | 0.00878214655816941 |
GO:0006752 | group transfer coenzyme metabolic process | 0.00896171348440969 |
GO:0012506 | vesicle membrane | 0.00932030532341178 |
GO:0009141 | nucleoside triphosphate metabolic process | 0.00932030532341178 |
GO:0009152 | purine ribonucleotide biosynthetic process | 0.0094993236673797 |
GO:0006818 | hydrogen transport | 0.009678152953148 |
GO:0015662 | ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism | 0.0101896217294751 |
GO:0009260 | ribonucleotide biosynthetic process | 0.0103682295299337 |
GO:0008334 | histone mRNA metabolic process | 0.0104502479417977 |
GO:0006398 | histone mRNA 3'-end processing | 0.0104502479417977 |
GO:0009150 | purine ribonucleotide metabolic process | 0.0109027702625417 |
GO:0006164 | purine nucleotide biosynthetic process | 0.0110805182261044 |
GO:0000139 | Golgi membrane | 0.0122874565081795 |
GO:0016043 | cellular component organization and biogenesis | 0.0122937969140547 |
GO:0009259 | ribonucleotide metabolic process | 0.0122937969140547 |
GO:0006163 | purine nucleotide metabolic process | 0.0133460554113547 |
GO:0030136 | clathrin-coated vesicle | 0.0133460554113547 |
GO:0004797 | thymidine kinase activity | 0.0140176496158612 |
GO:0042625 | ATPase activity, coupled to transmembrane movement of ions | 0.0155181757503771 |
GO:0009108 | coenzyme biosynthetic process | 0.0160676712181081 |
GO:0031410 | cytoplasmic vesicle | 0.0167030811733568 |
GO:0030135 | coated vesicle | 0.0171744129955214 |
GO:0031982 | vesicle | 0.0174130932340225 |
GO:0015078 | hydrogen ion transmembrane transporter activity | 0.0182903938285974 |
GO:0065003 | macromolecular complex assembly | 0.0195806801547763 |
GO:0051188 | cofactor biosynthetic process | 0.0195806801547763 |
GO:0015077 | monovalent inorganic cation transmembrane transporter activity | 0.0195806801547763 |
GO:0019136 | deoxynucleoside kinase activity | 0.0203864894195307 |
GO:0017069 | snRNA binding | 0.0203864894195307 |
GO:0033176 | proton-transporting V-type ATPase complex | 0.023635378738937 |
GO:0007032 | endosome organization and biogenesis | 0.023635378738937 |
GO:0016471 | vacuolar proton-transporting V-type ATPase complex | 0.023635378738937 |
GO:0042626 | ATPase activity, coupled to transmembrane movement of substances | 0.025666442978984 |
GO:0043492 | ATPase activity, coupled to movement of substances | 0.025666442978984 |
GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.0258180711699936 |
GO:0015030 | Cajal body | 0.0258370423680537 |
GO:0015991 | ATP hydrolysis coupled proton transport | 0.0258370423680537 |
GO:0030130 | clathrin coat of trans-Golgi network vesicle | 0.0258370423680537 |
GO:0022607 | cellular component assembly | 0.0268907328992126 |
GO:0009165 | nucleotide biosynthetic process | 0.0270004433233914 |
GO:0012510 | trans-Golgi network transport vesicle membrane | 0.0283314092552593 |
GO:0015988 | energy coupled proton transport, against electrochemical gradient | 0.0283314092552593 |
GO:0015399 | primary active transmembrane transporter activity | 0.0284489783883669 |
GO:0015405 | P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.0284489783883669 |
GO:0022890 | inorganic cation transmembrane transporter activity | 0.029453131230454 |
GO:0004602 | glutathione peroxidase activity | 0.030630183309856 |
GO:0010038 | response to metal ion | 0.0333731215676864 |
GO:0008199 | ferric iron binding | 0.0333731215676864 |
GO:0030532 | small nuclear ribonucleoprotein complex | 0.0353561526702033 |
GO:0030660 | Golgi-associated vesicle membrane | 0.0353561526702033 |
GO:0030658 | transport vesicle membrane | 0.0353561526702033 |
GO:0019206 | nucleoside kinase activity | 0.0353561526702033 |
GO:0030140 | trans-Golgi network transport vesicle | 0.0382019566560164 |
GO:0017111 | nucleoside-triphosphatase activity | 0.0383366047387109 |
GO:0006732 | coenzyme metabolic process | 0.0388458469411079 |
GO:0030139 | endocytic vesicle | 0.0399241084609958 |
GO:0010035 | response to inorganic substance | 0.0399241084609958 |
GO:0006812 | cation transport | 0.0399695485103797 |
GO:0005768 | endosome | 0.0402453259276258 |
GO:0016462 | pyrophosphatase activity | 0.0411696170722686 |
GO:0044444 | cytoplasmic part | 0.0411696170722686 |
GO:0031124 | mRNA 3'-end processing | 0.0411696170722686 |
GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.0411696170722686 |
GO:0016817 | hydrolase activity, acting on acid anhydrides | 0.0411696170722686 |
GO:0009117 | nucleotide metabolic process | 0.0451322533584478 |
GO:0006888 | ER to Golgi vesicle-mediated transport | 0.0451322533584478 |
GO:0005774 | vacuolar membrane | 0.0451322533584478 |
GO:0016023 | cytoplasmic membrane-bound vesicle | 0.0468035196720562 |
GO:0051186 | cofactor metabolic process | 0.0468035196720562 |
GO:0031123 | RNA 3'-end processing | 0.0468035196720562 |
GO:0005773 | vacuole | 0.0480836459269845 |
GO:0030133 | transport vesicle | 0.0483825743086711 |
GO:0055086 | nucleobase, nucleoside and nucleotide metabolic process | 0.0483825743086711 |
GO:0031988 | membrane-bound vesicle | 0.0483825743086711 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
non-terminally differentiated cell | 1.63e-22 | 49 |
ectodermal cell | 3.67e-20 | 44 |
neurectodermal cell | 3.67e-20 | 44 |
neural cell | 4.03e-20 | 43 |
electrically responsive cell | 1.58e-16 | 39 |
electrically active cell | 1.58e-16 | 39 |
somatic cell | 3.05e-16 | 118 |
animal cell | 1.16e-14 | 115 |
eukaryotic cell | 1.16e-14 | 115 |
somatic stem cell | 2.03e-14 | 91 |
multi fate stem cell | 2.03e-14 | 91 |
neuron | 2.81e-14 | 33 |
neuronal stem cell | 2.81e-14 | 33 |
neuroblast | 2.81e-14 | 33 |
electrically signaling cell | 2.81e-14 | 33 |
embryonic cell | 4.31e-14 | 70 |
stem cell | 1.36e-12 | 97 |
CNS neuron (sensu Vertebrata) | 4.78e-12 | 23 |
neuroblast (sensu Vertebrata) | 4.78e-12 | 23 |
migratory neural crest cell | 7.19e-07 | 10 |
neuron associated cell | 7.19e-07 | 10 |
glial cell (sensu Vertebrata) | 7.19e-07 | 10 |
neuron associated cell (sensu Vertebrata) | 7.19e-07 | 10 |
glial cell | 7.19e-07 | 10 |
glioblast | 7.19e-07 | 10 |
glioblast (sensu Vertebrata) | 7.19e-07 | 10 |
Ontology term | p-value | n |
---|---|---|
nervous system | 1.81e-30 | 75 |
central nervous system | 1.38e-29 | 73 |
ectoderm-derived structure | 1.89e-23 | 95 |
ectoderm | 1.89e-23 | 95 |
presumptive ectoderm | 1.89e-23 | 95 |
regional part of nervous system | 2.70e-21 | 54 |
neural tube | 5.42e-20 | 52 |
neural rod | 5.42e-20 | 52 |
future spinal cord | 5.42e-20 | 52 |
neural keel | 5.42e-20 | 52 |
neurectoderm | 1.10e-17 | 64 |
neural plate | 1.10e-17 | 64 |
presumptive neural plate | 1.10e-17 | 64 |
brain | 4.20e-17 | 47 |
future brain | 4.20e-17 | 47 |
regional part of brain | 6.21e-17 | 46 |
gray matter | 1.27e-16 | 34 |
anterior neural tube | 1.46e-14 | 40 |
ecto-epithelium | 1.65e-14 | 73 |
regional part of forebrain | 3.53e-14 | 39 |
forebrain | 3.53e-14 | 39 |
future forebrain | 3.53e-14 | 39 |
brain grey matter | 4.67e-14 | 29 |
regional part of telencephalon | 4.67e-14 | 29 |
telencephalon | 4.67e-14 | 29 |
structure with developmental contribution from neural crest | 1.15e-11 | 92 |
pre-chordal neural plate | 1.25e-11 | 49 |
cerebral cortex | 2.92e-10 | 21 |
cerebral hemisphere | 2.92e-10 | 21 |
pallium | 2.92e-10 | 21 |
regional part of cerebral cortex | 5.66e-09 | 17 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 1.8759 |
MA0004.1 | 3.03297 |
MA0006.1 | 1.31921 |
MA0007.1 | 0.82717 |
MA0009.1 | 0.337492 |
MA0014.1 | 6.29301 |
MA0017.1 | 0.241082 |
MA0019.1 | 0.205515 |
MA0024.1 | 0.820639 |
MA0025.1 | 0.530879 |
MA0027.1 | 1.89129 |
MA0028.1 | 6.63563 |
MA0029.1 | 0.287662 |
MA0030.1 | 0.292547 |
MA0031.1 | 0.266391 |
MA0038.1 | 0.425709 |
MA0040.1 | 0.347276 |
MA0041.1 | 0.155958 |
MA0042.1 | 0.036061 |
MA0043.1 | 0.415031 |
MA0046.1 | 0.365786 |
MA0048.1 | 1.41666 |
MA0050.1 | 0.59417 |
MA0051.1 | 0.862788 |
MA0052.1 | 0.353618 |
MA0055.1 | 0.2045 |
MA0056.1 | 0 |
MA0057.1 | 0.400394 |
MA0058.1 | 4.08724 |
MA0059.1 | 0.620066 |
MA0060.1 | 5.56512 |
MA0061.1 | 0.466178 |
MA0063.1 | 0 |
MA0066.1 | 0.41007 |
MA0067.1 | 0.629308 |
MA0068.1 | 0.0146185 |
MA0069.1 | 0.353886 |
MA0070.1 | 0.346258 |
MA0071.1 | 0.0830235 |
MA0072.1 | 0.339628 |
MA0073.1 | 0.0120521 |
MA0074.1 | 0.360358 |
MA0076.1 | 8.06312 |
MA0077.1 | 0.32285 |
MA0078.1 | 0.161775 |
MA0081.1 | 0.688174 |
MA0083.1 | 0.414379 |
MA0084.1 | 0.934141 |
MA0087.1 | 0.379309 |
MA0088.1 | 2.55794 |
MA0089.1 | 0 |
MA0090.1 | 0.198563 |
MA0091.1 | 0.0722516 |
MA0092.1 | 0.439746 |
MA0093.1 | 5.36672 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.701922 |
MA0101.1 | 0.646174 |
MA0103.1 | 0.258738 |
MA0105.1 | 0.92278 |
MA0106.1 | 0.498719 |
MA0107.1 | 0.75593 |
MA0108.2 | 0.629361 |
MA0109.1 | 0 |
MA0111.1 | 0.467988 |
MA0113.1 | 0.149628 |
MA0114.1 | 0.0460994 |
MA0115.1 | 0.417336 |
MA0116.1 | 0.639448 |
MA0117.1 | 0.390961 |
MA0119.1 | 0.0405474 |
MA0122.1 | 0.407133 |
MA0124.1 | 0.581749 |
MA0125.1 | 0.516802 |
MA0130.1 | 0 |
MA0131.1 | 2.46035 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.445266 |
MA0136.1 | 0.775995 |
MA0139.1 | 1.60281 |
MA0140.1 | 0.105959 |
MA0141.1 | 0.0297262 |
MA0142.1 | 0.255956 |
MA0143.1 | 0.159321 |
MA0144.1 | 0.468617 |
MA0145.1 | 2.04381 |
MA0146.1 | 3.5853 |
MA0147.1 | 0.509447 |
MA0148.1 | 0.0735508 |
MA0149.1 | 0.0420811 |
MA0062.2 | 5.79247 |
MA0035.2 | 0.108338 |
MA0039.2 | 4.91635 |
MA0138.2 | 0.197313 |
MA0002.2 | 0.0696121 |
MA0137.2 | 0.5305 |
MA0104.2 | 1.39556 |
MA0047.2 | 0.136816 |
MA0112.2 | 0.714902 |
MA0065.2 | 0.254159 |
MA0150.1 | 0.219664 |
MA0151.1 | 0 |
MA0152.1 | 0.424765 |
MA0153.1 | 0.459241 |
MA0154.1 | 0.448933 |
MA0155.1 | 1.34988 |
MA0156.1 | 0.807998 |
MA0157.1 | 0.233393 |
MA0158.1 | 0 |
MA0159.1 | 0.0603505 |
MA0160.1 | 0.0748272 |
MA0161.1 | 0 |
MA0162.1 | 4.44727 |
MA0163.1 | 0.427523 |
MA0164.1 | 0.122585 |
MA0080.2 | 0.47059 |
MA0018.2 | 0.800068 |
MA0099.2 | 0.193216 |
MA0079.2 | 1.71659 |
MA0102.2 | 0.984244 |
MA0258.1 | 0.415286 |
MA0259.1 | 0.727482 |
MA0442.1 | 0 |