MCL coexpression mm9:1968: Difference between revisions
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{{MCL_coexpression_mm9 | 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O-acyltransferase activity;0.00562138780611094;68393!GO:0006104;succinyl-CoA metabolic process;0.00562138780611094;171282!GO:0046459;short-chain fatty acid metabolic process;0.00562138780611094;171282!GO:0006651;diacylglycerol biosynthetic process;0.00562138780611094;68393!GO:0003846;2-acylglycerol O-acyltransferase activity;0.00562138780611094;68393!GO:0046460;neutral lipid biosynthetic process;0.00562138780611094;68393!GO:0046463;acylglycerol biosynthetic process;0.00562138780611094;68393!GO:0044255;cellular lipid metabolic process;0.00562138780611094;171282,68393!GO:0046339;diacylglycerol metabolic process;0.00562138780611094;68393!GO:0046504;glycerol ether biosynthetic process;0.00562138780611094;68393!GO:0045017;glycerolipid biosynthetic process;0.00562138780611094;68393!GO:0043648;dicarboxylic acid metabolic process;0.00562138780611094;171282!GO:0006629;lipid metabolic process;0.00562138780611094;171282,68393!GO:0016290;palmitoyl-CoA hydrolase activity;0.00603086878670909;171282!GO:0006637;acyl-CoA metabolic process;0.00603086878670909;171282!GO:0016291;acyl-CoA thioesterase activity;0.00603086878670909;171282!GO:0016411;acylglycerol O-acyltransferase activity;0.00603086878670909;68393!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.00657174040685285;171282!GO:0016289;CoA hydrolase activity;0.00664073462887965;171282!GO:0006071;glycerol metabolic process;0.00749096282138268;68393!GO:0019751;polyol metabolic process;0.0075095313391231;68393!GO:0006639;acylglycerol metabolic process;0.00819905965580648;68393!GO:0046486;glycerolipid metabolic process;0.00819905965580648;68393!GO:0006638;neutral lipid metabolic process;0.00819905965580648;68393!GO:0006662;glycerol ether metabolic process;0.00819905965580648;68393!GO:0008374;O-acyltransferase activity;0.00909559239437412;68393!GO:0045454;cell redox homeostasis;0.0122581718694476;68393!GO:0042579;microbody;0.0230862485008273;171282!GO:0005777;peroxisome;0.0230862485008273;171282!GO:0016790;thiolester hydrolase activity;0.0230862485008273;171282!GO:0006732;coenzyme metabolic process;0.0392737580302111;171282!GO:0006631;fatty acid metabolic process;0.0392737580302111;171282!GO:0008415;acyltransferase activity;0.0394928238126641;68393!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0394928238126641;68393!GO:0016746;transferase activity, transferring acyl groups;0.039927238538215;68393!GO:0051186;cofactor metabolic process;0.0407707605133528;171282!GO:0019725;cellular homeostasis;0.0439637461505754;68393!GO:0032787;monocarboxylic acid metabolic process;0.0439637461505754;171282!GO:0008610;lipid biosynthetic process;0.0474319260194453;68393!GO:0044262;cellular carbohydrate metabolic process;0.0481029168663236;171282!GO:0006066;alcohol metabolic process;0.0481029168663236;68393!GO:0044444;cytoplasmic 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|coexpression_dpi_cluster_scores_median=0.0179638091157646,0.783028694009053,0.77955085607886,0.721471376269493,0.534628663247761,0.405380480131378,0.277391079733873,0,0.0286026095447835,0,-0.0142930472775233,-0.0142930472775233,0,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.00986498922783855,-0.0142930472775233,0.190947417941288,0,-0.0142930472775233,0.475609689275848,0.451915472409148,0.493681807531967,0.433932292704005,0.532791015953405,0.548208164671812,0.559507537208952,0.412360099518427,0,0,-0.0142930472775233,0.2095818385276,0.082214073215242,0.163811459641192,0,0,0,0.100456901012675,0,0,0.0114562485853226,0,0,0,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.00473022745926369,0,0,0.0235953597542039,-0.0142930472775233,-0.00207922303535088,-0.0142930472775233,-0.0142930472775233,0,0,0,0,0,0,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0.0290414042637407,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0,0,-0.0142930472775233,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0.333952270749752,0.427191505783655,0.592690993704579,0.585722479473835,0.559592206532751,0.591705100716506,0.42847498043046,0,-0.00124703073291562,0,0,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0040016924969547,-0.0142930472775233,0.767990335840061,0,0.0421575654322454,0,0,0.0307681426712156,0.0301630883840162,0.101636919766843,0.0371167295723915,0.106179278422736,0.176114115617577,-0.0142930472775233,-0.00867162019422605,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0.0616818391008725,0.350145370846173,0.0474108402190278,0,0.110560856212573,-0.0142930472775233,-0.0142930472775233,0,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0,0.0545771569094645,0.0346344364219235,0.0829439327499637,-0.0142930472775233,-0.0142930472775233,0,0.0161889184355898,0,-0.0142930472775233,-0.0142930472775233,0.0242799873270616,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0,0,0,0.018637936060662,-0.0142930472775233,0,0,0,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0131770499301714,-0.0142930472775233,0,-0.0142930472775233,0.018714681493779,0.0499052450664022,0.015337152401075,0,0,-0.0142930472775233,0,0.644291131592532,0.4337803506596,0,0,0.049794559917327,0.11105491646589,0.273542433540762,0.174764834656404,0.375970295951557,0.442333762576098,0.322629532662897,0.366404638058233,0.330916897148892,0.470274356366267,0.342384775494342,0.509880999760393,0.061132696541412,0,0,0.0805006992779881,0.148898717368552,0.223858359404601,0.4116646458131,0.553872717151152,0.626101971930077,0.621487632699641,0.478470961908526,0.0766450745821094,0.100654443375295,0.0933798259277435,0,0.233390619373342,0.0453965179663154,0.331834416681433,0.735631418547047,0.716894935881004,1.07043196430336,1.06957152735683,0.953369493679857,0.763117371325664,0.634620865938103,0.962243234395139,0.05398898267758,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,0,0,0,-0.0102056828717318,0.0259202081385316,-0.0142930472775233,0.0658175593689868,0,0.0800173357455855,-0.0142930472775233,0.005525772709557,-0.0142930472775233,0.000424912788244914,-0.0072428719573948,0.074466813053769,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,-0.00940422481526885,0.0288216590713588,-0.0142930472775233,0,-0.0065640042223058,0.125466933248368,-0.0142930472775233,0,0.0375187909878671,0.0971345155168213,0.0439170307125511,0.186262130861894,0,0.0519164321051767,0,-0.0142930472775233,-0.0142930472775233,0,0,0,0,0,0,0,0,0.0314827010224724,0.103141507795097,0,0.18297249658601,0.0182099091120593,0.0946453069838865,0.127852400356445,0.0734808406062816,0.388192053466363,0,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0.0197958802532516,0.09027203006171,0.0419255239995323,0.293530634667673,-0.0142930472775233,-0.0142930472775233,0.0222709268946923,0.0269359613297282,0.078686843694125,0.180597085442738,0.366730584815937,0.091422923116439,0.301713596670305,0,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,-0.0142930472775233,0.0263777085807213,-0.0142930472775233,0,0.0531569878936061,0.00736044927697325,-0.0142930472775233,0,-0.0142930472775233,-0.0142930472775233,0,-0.0142930472775233,0,0,0,-0.0142930472775233,0.0065939951218895,0,0,-0.0142930472775233,0,0.00970960747666175,0.0686789557509465,-0.0142930472775233,0.0186562366721724,0.0289222934736898,-0.0142930472775233,0,-0.0142930472775233,0.0514692832714496,0,0,-0.0142468118206729,-0.0142930472775233,0,0,-0.0142930472775233,-0.0142930472775233,0,0,-0.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| |||
|gostat_on_MCL_coexpression=GO:0004144;diacylglycerol O-acyltransferase activity;0.00562138780611094;68393!GO:0006104;succinyl-CoA metabolic process;0.00562138780611094;171282!GO:0046459;short-chain fatty acid metabolic process;0.00562138780611094;171282!GO:0006651;diacylglycerol biosynthetic process;0.00562138780611094;68393!GO:0003846;2-acylglycerol O-acyltransferase activity;0.00562138780611094;68393!GO:0046460;neutral lipid biosynthetic process;0.00562138780611094;68393!GO:0046463;acylglycerol biosynthetic process;0.00562138780611094;68393!GO:0044255;cellular lipid metabolic process;0.00562138780611094;171282,68393!GO:0046339;diacylglycerol metabolic process;0.00562138780611094;68393!GO:0046504;glycerol ether biosynthetic process;0.00562138780611094;68393!GO:0045017;glycerolipid biosynthetic process;0.00562138780611094;68393!GO:0043648;dicarboxylic acid metabolic process;0.00562138780611094;171282!GO:0006629;lipid metabolic process;0.00562138780611094;171282,68393!GO:0016290;palmitoyl-CoA hydrolase activity;0.00603086878670909;171282!GO:0006637;acyl-CoA metabolic process;0.00603086878670909;171282!GO:0016291;acyl-CoA thioesterase activity;0.00603086878670909;171282!GO:0016411;acylglycerol O-acyltransferase activity;0.00603086878670909;68393!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.00657174040685285;171282!GO:0016289;CoA hydrolase activity;0.00664073462887965;171282!GO:0006071;glycerol metabolic process;0.00749096282138268;68393!GO:0019751;polyol metabolic process;0.0075095313391231;68393!GO:0006639;acylglycerol metabolic process;0.00819905965580648;68393!GO:0046486;glycerolipid metabolic process;0.00819905965580648;68393!GO:0006638;neutral lipid metabolic process;0.00819905965580648;68393!GO:0006662;glycerol ether metabolic process;0.00819905965580648;68393!GO:0008374;O-acyltransferase activity;0.00909559239437412;68393!GO:0045454;cell redox homeostasis;0.0122581718694476;68393!GO:0042579;microbody;0.0230862485008273;171282!GO:0005777;peroxisome;0.0230862485008273;171282!GO:0016790;thiolester hydrolase activity;0.0230862485008273;171282!GO:0006732;coenzyme metabolic process;0.0392737580302111;171282!GO:0006631;fatty acid metabolic process;0.0392737580302111;171282!GO:0008415;acyltransferase activity;0.0394928238126641;68393!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0394928238126641;68393!GO:0016746;transferase activity, transferring acyl groups;0.039927238538215;68393!GO:0051186;cofactor metabolic process;0.0407707605133528;171282!GO:0019725;cellular homeostasis;0.0439637461505754;68393!GO:0032787;monocarboxylic acid metabolic process;0.0439637461505754;171282!GO:0008610;lipid biosynthetic process;0.0474319260194453;68393!GO:0044262;cellular carbohydrate metabolic process;0.0481029168663236;171282!GO:0006066;alcohol metabolic process;0.0481029168663236;68393!GO:0044444;cytoplasmic part;0.0481029168663236;171282,68393! | |||
|ontology_enrichment_celltype= | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0000160!8.89e-13!31;UBERON:0002107!6.69e-12!22;UBERON:0007499!6.69e-12!22;UBERON:0006925!6.69e-12!22;UBERON:0009497!6.69e-12!22;UBERON:0000015!6.69e-12!22;UBERON:0002423!6.69e-12!22;UBERON:0006235!6.69e-12!22;UBERON:0008835!6.69e-12!22;UBERON:0003894!6.69e-12!22;UBERON:0004161!6.69e-12!22;UBERON:0008836!6.69e-12!22;UBERON:0009854!1.06e-10!23;UBERON:0009856!1.06e-10!23;UBERON:0002365!3.90e-10!25;UBERON:0002330!3.90e-10!25;UBERON:0005172!1.34e-09!49;UBERON:0005173!1.34e-09!49;UBERON:0002417!1.34e-09!49;UBERON:0000916!1.34e-09!49;UBERON:0000344!2.55e-09!15;UBERON:0005409!4.52e-09!47;UBERON:0004119!1.15e-08!118;UBERON:0000925!1.15e-08!118;UBERON:0006595!1.15e-08!118;UBERON:0001007!2.89e-08!116;UBERON:0001555!2.89e-08!116;UBERON:0007026!2.89e-08!116;UBERON:0001242!3.17e-08!13;UBERON:0000060!3.17e-08!13;UBERON:0001262!3.17e-08!13;UBERON:0004786!3.17e-08!13;UBERON:0003104!3.48e-08!61;UBERON:0009142!3.48e-08!61;UBERON:0005256!1.10e-07!45;UBERON:0004921!1.56e-07!114 | |||
}} |
Latest revision as of 17:47, 17 September 2013
Phase1 CAGE Peaks
Short description | |
---|---|
Mm9::chr11:49059026..49059041,+ | p9@Mgat1 |
Mm9::chr12:85379313..85379329,+ | p2@Acot4 |
Mm9::chr18:61878972..61878986,- | p@chr18:61878972..61878986 - |
Mm9::chr7:134985979..134986002,- | p@chr7:134985979..134986002 - |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0004144 | diacylglycerol O-acyltransferase activity | 0.00562138780611094 |
GO:0006104 | succinyl-CoA metabolic process | 0.00562138780611094 |
GO:0046459 | short-chain fatty acid metabolic process | 0.00562138780611094 |
GO:0006651 | diacylglycerol biosynthetic process | 0.00562138780611094 |
GO:0003846 | 2-acylglycerol O-acyltransferase activity | 0.00562138780611094 |
GO:0046460 | neutral lipid biosynthetic process | 0.00562138780611094 |
GO:0046463 | acylglycerol biosynthetic process | 0.00562138780611094 |
GO:0044255 | cellular lipid metabolic process | 0.00562138780611094 |
GO:0046339 | diacylglycerol metabolic process | 0.00562138780611094 |
GO:0046504 | glycerol ether biosynthetic process | 0.00562138780611094 |
GO:0045017 | glycerolipid biosynthetic process | 0.00562138780611094 |
GO:0043648 | dicarboxylic acid metabolic process | 0.00562138780611094 |
GO:0006629 | lipid metabolic process | 0.00562138780611094 |
GO:0016290 | palmitoyl-CoA hydrolase activity | 0.00603086878670909 |
GO:0006637 | acyl-CoA metabolic process | 0.00603086878670909 |
GO:0016291 | acyl-CoA thioesterase activity | 0.00603086878670909 |
GO:0016411 | acylglycerol O-acyltransferase activity | 0.00603086878670909 |
GO:0006100 | tricarboxylic acid cycle intermediate metabolic process | 0.00657174040685285 |
GO:0016289 | CoA hydrolase activity | 0.00664073462887965 |
GO:0006071 | glycerol metabolic process | 0.00749096282138268 |
GO:0019751 | polyol metabolic process | 0.0075095313391231 |
GO:0006639 | acylglycerol metabolic process | 0.00819905965580648 |
GO:0046486 | glycerolipid metabolic process | 0.00819905965580648 |
GO:0006638 | neutral lipid metabolic process | 0.00819905965580648 |
GO:0006662 | glycerol ether metabolic process | 0.00819905965580648 |
GO:0008374 | O-acyltransferase activity | 0.00909559239437412 |
GO:0045454 | cell redox homeostasis | 0.0122581718694476 |
GO:0042579 | microbody | 0.0230862485008273 |
GO:0005777 | peroxisome | 0.0230862485008273 |
GO:0016790 | thiolester hydrolase activity | 0.0230862485008273 |
GO:0006732 | coenzyme metabolic process | 0.0392737580302111 |
GO:0006631 | fatty acid metabolic process | 0.0392737580302111 |
GO:0008415 | acyltransferase activity | 0.0394928238126641 |
GO:0016747 | transferase activity, transferring groups other than amino-acyl groups | 0.0394928238126641 |
GO:0016746 | transferase activity, transferring acyl groups | 0.039927238538215 |
GO:0051186 | cofactor metabolic process | 0.0407707605133528 |
GO:0019725 | cellular homeostasis | 0.0439637461505754 |
GO:0032787 | monocarboxylic acid metabolic process | 0.0439637461505754 |
GO:0008610 | lipid biosynthetic process | 0.0474319260194453 |
GO:0044262 | cellular carbohydrate metabolic process | 0.0481029168663236 |
GO:0006066 | alcohol metabolic process | 0.0481029168663236 |
GO:0044444 | cytoplasmic part | 0.0481029168663236 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.0356887 |
MA0004.1 | 1.64673 |
MA0006.1 | 1.24418 |
MA0007.1 | 0.672186 |
MA0009.1 | 1.15569 |
MA0014.1 | 0.0809287 |
MA0017.1 | 2.25393 |
MA0019.1 | 0.964875 |
MA0024.1 | 1.11019 |
MA0025.1 | 1.39562 |
MA0027.1 | 2.81824 |
MA0028.1 | 0.509589 |
MA0029.1 | 1.08753 |
MA0030.1 | 1.09438 |
MA0031.1 | 1.05719 |
MA0038.1 | 0.846479 |
MA0040.1 | 1.16866 |
MA0041.1 | 0.604221 |
MA0042.1 | 0.589368 |
MA0043.1 | 1.25564 |
MA0046.1 | 1.1929 |
MA0048.1 | 0.266382 |
MA0050.1 | 2.90785 |
MA0051.1 | 0.856094 |
MA0052.1 | 1.17701 |
MA0055.1 | 0.125758 |
MA0056.1 | 0 |
MA0057.1 | 0.251896 |
MA0058.1 | 2.42845 |
MA0059.1 | 2.47352 |
MA0060.1 | 0.403071 |
MA0061.1 | 0.438628 |
MA0063.1 | 0 |
MA0066.1 | 1.94802 |
MA0067.1 | 1.50873 |
MA0068.1 | 0.713436 |
MA0069.1 | 1.17737 |
MA0070.1 | 1.16732 |
MA0071.1 | 0.73062 |
MA0072.1 | 1.15853 |
MA0073.1 | 0.783927 |
MA0074.1 | 0.795862 |
MA0076.1 | 0.550092 |
MA0077.1 | 1.13603 |
MA0078.1 | 0.891476 |
MA0081.1 | 0.621611 |
MA0083.1 | 1.25482 |
MA0084.1 | 1.84013 |
MA0087.1 | 1.21037 |
MA0088.1 | 0.582815 |
MA0089.1 | 0 |
MA0090.1 | 0.650768 |
MA0091.1 | 0.703314 |
MA0092.1 | 0.651119 |
MA0093.1 | 2.22418 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.783305 |
MA0101.1 | 0.605676 |
MA0103.1 | 0.540576 |
MA0105.1 | 0.313353 |
MA0106.1 | 0.899777 |
MA0107.1 | 0.533522 |
MA0108.2 | 0.989014 |
MA0109.1 | 0 |
MA0111.1 | 0.666525 |
MA0113.1 | 0.869608 |
MA0114.1 | 2.89957 |
MA0115.1 | 1.25852 |
MA0116.1 | 0.497293 |
MA0117.1 | 1.22527 |
MA0119.1 | 0.606338 |
MA0122.1 | 1.24573 |
MA0124.1 | 1.45461 |
MA0125.1 | 1.37907 |
MA0130.1 | 0 |
MA0131.1 | 0.960068 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 1.29308 |
MA0136.1 | 0.817395 |
MA0139.1 | 0.365453 |
MA0140.1 | 0.78318 |
MA0141.1 | 0.563066 |
MA0142.1 | 1.04199 |
MA0143.1 | 0.887119 |
MA0144.1 | 1.11951 |
MA0145.1 | 0.21199 |
MA0146.1 | 0.0944145 |
MA0147.1 | 1.15069 |
MA0148.1 | 1.68395 |
MA0149.1 | 0.611881 |
MA0062.2 | 0.319836 |
MA0035.2 | 0.788288 |
MA0039.2 | 0.731226 |
MA0138.2 | 0.951653 |
MA0002.2 | 0.368961 |
MA0137.2 | 1.37638 |
MA0104.2 | 1.0034 |
MA0047.2 | 0.845655 |
MA0112.2 | 0.211985 |
MA0065.2 | 1.79447 |
MA0150.1 | 0.67206 |
MA0151.1 | 0 |
MA0152.1 | 0.84577 |
MA0153.1 | 1.31015 |
MA0154.1 | 0.263609 |
MA0155.1 | 0.230016 |
MA0156.1 | 0.549102 |
MA0157.1 | 1.0083 |
MA0158.1 | 0 |
MA0159.1 | 1.1762 |
MA0160.1 | 0.71003 |
MA0161.1 | 0 |
MA0162.1 | 0.346529 |
MA0163.1 | 0.672192 |
MA0164.1 | 0.817786 |
MA0080.2 | 0.534538 |
MA0018.2 | 0.828253 |
MA0099.2 | 0.944966 |
MA0079.2 | 0.612404 |
MA0102.2 | 1.8929 |
MA0258.1 | 0.419871 |
MA0259.1 | 1.12353 |
MA0442.1 | 0 |