Coexpression cluster:C205: Difference between revisions
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|gostat_on_coexpression_clusters=GO:0006955!immune response!0.000349807746282106!4065;27040;7293;55801;6346;4049$GO:0002376!immune system process!0.000426313808965761!4065;27040;7293;55801;6346;4049$GO:0019722!calcium-mediated signaling!0.00630455178790549!27040;4049$GO:0005125!cytokine activity!0.00973443726723401!55801;6346;4049$GO:0051952!regulation of amine transport!0.0168129406759757!4049$GO:0002036!regulation of L-glutamate transport!0.0168129406759757!4049$GO:0051953!negative regulation of amine transport!0.0168129406759757!4049$GO:0051956!negative regulation of amino acid transport!0.0168129406759757!4049$GO:0002037!negative regulation of L-glutamate transport!0.0168129406759757!4049$GO:0051955!regulation of amino acid transport!0.0168129406759757!4049$GO:0005615!extracellular space!0.0168129406759757!55801;6346;4049$GO:0009605!response to external stimulus!0.0247994292453115!4065;6346;4049$GO:0007267!cell-cell signaling!0.0247994292453115!55801;6346;4049$GO:0046325!negative regulation of glucose import!0.0252186099539889!4049$GO:0048535!lymph node development!0.0271409218658873!4049$GO:0050806!positive regulation of synaptic transmission!0.0271409218658873!4049$GO:0001775!cell activation!0.0271409218658873!27040;4049$GO:0051971!positive regulation of transmission of nerve impulse!0.0271409218658873!4049$GO:0043303!mast cell degranulation!0.0271409218658873!27040$GO:0002448!mast cell mediated immunity!0.0271409218658873!27040$GO:0045576!mast cell activation!0.0271409218658873!27040$GO:0043299!leukocyte degranulation!0.0271409218658873!27040$GO:0046323!glucose import!0.0271409218658873!4049$GO:0046324!regulation of glucose import!0.0271409218658873!4049$GO:0031646!positive regulation of neurological process!0.0271409218658873!4049$GO:0005031!tumor necrosis factor receptor activity!0.0271409218658873!7293$GO:0043525!positive regulation of neuron apoptosis!0.0273704643242504!4049$GO:0002444!myeloid leukocyte mediated immunity!0.0273704643242504!27040$GO:0043120!tumor necrosis factor binding!0.0273704643242504!7293$GO:0044421!extracellular region part!0.027743861225859!55801;6346;4049$GO:0005035!death receptor activity!0.027743861225859!7293$GO:0016021!integral to membrane!0.027743861225859!7352;4065;780776;27040;7293;120425;4049$GO:0031224!intrinsic to membrane!0.027743861225859!7352;4065;780776;27040;7293;120425;4049$GO:0051222!positive regulation of protein transport!0.027743861225859!4049$GO:0019932!second-messenger-mediated signaling!0.027743861225859!27040;4049$GO:0051239!regulation of multicellular organismal process!0.0285894817718104!27040;4049$GO:0045840!positive regulation of mitosis!0.0285894817718104!4049$GO:0006954!inflammatory response!0.028644406585695!4065;6346$GO:0015813!L-glutamate transport!0.028644406585695!4049$GO:0015800!acidic amino acid transport!0.028644406585695!4049$GO:0005102!receptor binding!0.030947997828804!55801;6346;4049$GO:0050804!regulation of synaptic transmission!0.033559563047681!4049$GO:0009612!response to mechanical stimulus!0.0340307536623605!4049$GO:0001772!immunological synapse!0.0340307536623605!27040$GO:0051969!regulation of transmission of nerve impulse!0.0352261380904179!4049$GO:0044459!plasma membrane part!0.0354480104691158!4065;27040;7293;120425$GO:0016020!membrane!0.0372626362680686!7352;4065;23180;27040;120425;780776;7293;4049$GO:0005886!plasma membrane!0.0372626362680686!4065;23180;27040;7293;120425$GO:0044425!membrane part!0.0422303467262425!7352;4065;780776;27040;7293;120425;4049$GO:0045787!positive regulation of progression through cell cycle!0.0422303467262425!4049$GO:0031644!regulation of neurological process!0.0422911808133526!4049$GO:0043523!regulation of neuron apoptosis!0.0422911808133526!4049$GO:0009611!response to wounding!0.0439685993139882!4065;6346$GO:0002274!myeloid leukocyte activation!0.0439685993139882!27040$GO:0051223!regulation of protein transport!0.0447607868065524!4049$GO:0007585!respiratory gaseous exchange!0.0453502471319412!7352$GO:0051402!neuron apoptosis!0.0453502471319412!4049$GO:0015758!glucose transport!0.0453502471319412!4049$GO:0051051!negative regulation of transport!0.0453502471319412!4049$GO:0008645!hexose transport!0.0453502471319412!4049$GO:0015749!monosaccharide transport!0.0453502471319412!4049$GO:0003993!acid phosphatase activity!0.0453502471319412!92370 | |gostat_on_coexpression_clusters=GO:0006955!immune response!0.000349807746282106!4065;27040;7293;55801;6346;4049$GO:0002376!immune system process!0.000426313808965761!4065;27040;7293;55801;6346;4049$GO:0019722!calcium-mediated signaling!0.00630455178790549!27040;4049$GO:0005125!cytokine activity!0.00973443726723401!55801;6346;4049$GO:0051952!regulation of amine transport!0.0168129406759757!4049$GO:0002036!regulation of L-glutamate transport!0.0168129406759757!4049$GO:0051953!negative regulation of amine transport!0.0168129406759757!4049$GO:0051956!negative regulation of amino acid transport!0.0168129406759757!4049$GO:0002037!negative regulation of L-glutamate transport!0.0168129406759757!4049$GO:0051955!regulation of amino acid transport!0.0168129406759757!4049$GO:0005615!extracellular space!0.0168129406759757!55801;6346;4049$GO:0009605!response to external stimulus!0.0247994292453115!4065;6346;4049$GO:0007267!cell-cell signaling!0.0247994292453115!55801;6346;4049$GO:0046325!negative regulation of glucose import!0.0252186099539889!4049$GO:0048535!lymph node development!0.0271409218658873!4049$GO:0050806!positive regulation of synaptic transmission!0.0271409218658873!4049$GO:0001775!cell activation!0.0271409218658873!27040;4049$GO:0051971!positive regulation of transmission of nerve impulse!0.0271409218658873!4049$GO:0043303!mast cell degranulation!0.0271409218658873!27040$GO:0002448!mast cell mediated immunity!0.0271409218658873!27040$GO:0045576!mast cell activation!0.0271409218658873!27040$GO:0043299!leukocyte degranulation!0.0271409218658873!27040$GO:0046323!glucose import!0.0271409218658873!4049$GO:0046324!regulation of glucose import!0.0271409218658873!4049$GO:0031646!positive regulation of neurological process!0.0271409218658873!4049$GO:0005031!tumor necrosis factor receptor activity!0.0271409218658873!7293$GO:0043525!positive regulation of neuron apoptosis!0.0273704643242504!4049$GO:0002444!myeloid leukocyte mediated immunity!0.0273704643242504!27040$GO:0043120!tumor necrosis factor binding!0.0273704643242504!7293$GO:0044421!extracellular region part!0.027743861225859!55801;6346;4049$GO:0005035!death receptor activity!0.027743861225859!7293$GO:0016021!integral to membrane!0.027743861225859!7352;4065;780776;27040;7293;120425;4049$GO:0031224!intrinsic to membrane!0.027743861225859!7352;4065;780776;27040;7293;120425;4049$GO:0051222!positive regulation of protein transport!0.027743861225859!4049$GO:0019932!second-messenger-mediated signaling!0.027743861225859!27040;4049$GO:0051239!regulation of multicellular organismal process!0.0285894817718104!27040;4049$GO:0045840!positive regulation of mitosis!0.0285894817718104!4049$GO:0006954!inflammatory response!0.028644406585695!4065;6346$GO:0015813!L-glutamate transport!0.028644406585695!4049$GO:0015800!acidic amino acid transport!0.028644406585695!4049$GO:0005102!receptor binding!0.030947997828804!55801;6346;4049$GO:0050804!regulation of synaptic transmission!0.033559563047681!4049$GO:0009612!response to mechanical stimulus!0.0340307536623605!4049$GO:0001772!immunological synapse!0.0340307536623605!27040$GO:0051969!regulation of transmission of nerve impulse!0.0352261380904179!4049$GO:0044459!plasma membrane part!0.0354480104691158!4065;27040;7293;120425$GO:0016020!membrane!0.0372626362680686!7352;4065;23180;27040;120425;780776;7293;4049$GO:0005886!plasma membrane!0.0372626362680686!4065;23180;27040;7293;120425$GO:0044425!membrane part!0.0422303467262425!7352;4065;780776;27040;7293;120425;4049$GO:0045787!positive regulation of progression through cell cycle!0.0422303467262425!4049$GO:0031644!regulation of neurological process!0.0422911808133526!4049$GO:0043523!regulation of neuron apoptosis!0.0422911808133526!4049$GO:0009611!response to wounding!0.0439685993139882!4065;6346$GO:0002274!myeloid leukocyte activation!0.0439685993139882!27040$GO:0051223!regulation of protein transport!0.0447607868065524!4049$GO:0007585!respiratory gaseous exchange!0.0453502471319412!7352$GO:0051402!neuron apoptosis!0.0453502471319412!4049$GO:0015758!glucose transport!0.0453502471319412!4049$GO:0051051!negative regulation of transport!0.0453502471319412!4049$GO:0008645!hexose transport!0.0453502471319412!4049$GO:0015749!monosaccharide transport!0.0453502471319412!4049$GO:0003993!acid phosphatase activity!0.0453502471319412!92370 | ||
|id=C205 | |id=C205 | ||
|ontology_enrichment_celltype=CL:0000738!1.57e-22!140;CL:0002087!2.07e-19!119;CL:0000988!2.22e-19!182;CL:0002031!6.67e-19!124;CL:0000037!1.54e-18!172;CL:0000566!1.54e-18!172;CL:0002032!1.95e-17!165;CL:0000837!1.95e-17!165;CL:0000542!5.44e-17!53;CL:0000051!5.44e-17!53;CL:0000838!1.20e-16!52;CL:0000084!2.21e-15!25;CL:0000827!2.21e-15!25;CL:0000791!1.86e-11!18;CL:0000789!1.86e-11!18;CL:0002420!1.86e-11!18;CL:0002419!1.86e-11!18;CL:0000790!1.86e-11!18;CL:0000625!9.45e-08!11 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_uberon=UBERON:0002193!1.55e-13!112;UBERON:0002390!5.11e-13!102;UBERON:0003061!5.11e-13!102;UBERON:0000178!1.60e-08!15;UBERON:0000179!1.60e-08!15;UBERON:0000463!1.60e-08!15;UBERON:0007023!3.04e-07!115 | |||
}} | }} |
Revision as of 14:19, 21 May 2012
Full id: C205_mycosis_cord_hairy_xeroderma_CD4_B_b
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0006955 | immune response | 0.000349807746282106 |
GO:0002376 | immune system process | 0.000426313808965761 |
GO:0019722 | calcium-mediated signaling | 0.00630455178790549 |
GO:0005125 | cytokine activity | 0.00973443726723401 |
GO:0051952 | regulation of amine transport | 0.0168129406759757 |
GO:0002036 | regulation of L-glutamate transport | 0.0168129406759757 |
GO:0051953 | negative regulation of amine transport | 0.0168129406759757 |
GO:0051956 | negative regulation of amino acid transport | 0.0168129406759757 |
GO:0002037 | negative regulation of L-glutamate transport | 0.0168129406759757 |
GO:0051955 | regulation of amino acid transport | 0.0168129406759757 |
GO:0005615 | extracellular space | 0.0168129406759757 |
GO:0009605 | response to external stimulus | 0.0247994292453115 |
GO:0007267 | cell-cell signaling | 0.0247994292453115 |
GO:0046325 | negative regulation of glucose import | 0.0252186099539889 |
GO:0048535 | lymph node development | 0.0271409218658873 |
GO:0050806 | positive regulation of synaptic transmission | 0.0271409218658873 |
GO:0001775 | cell activation | 0.0271409218658873 |
GO:0051971 | positive regulation of transmission of nerve impulse | 0.0271409218658873 |
GO:0043303 | mast cell degranulation | 0.0271409218658873 |
GO:0002448 | mast cell mediated immunity | 0.0271409218658873 |
GO:0045576 | mast cell activation | 0.0271409218658873 |
GO:0043299 | leukocyte degranulation | 0.0271409218658873 |
GO:0046323 | glucose import | 0.0271409218658873 |
GO:0046324 | regulation of glucose import | 0.0271409218658873 |
GO:0031646 | positive regulation of neurological process | 0.0271409218658873 |
GO:0005031 | tumor necrosis factor receptor activity | 0.0271409218658873 |
GO:0043525 | positive regulation of neuron apoptosis | 0.0273704643242504 |
GO:0002444 | myeloid leukocyte mediated immunity | 0.0273704643242504 |
GO:0043120 | tumor necrosis factor binding | 0.0273704643242504 |
GO:0044421 | extracellular region part | 0.027743861225859 |
GO:0005035 | death receptor activity | 0.027743861225859 |
GO:0016021 | integral to membrane | 0.027743861225859 |
GO:0031224 | intrinsic to membrane | 0.027743861225859 |
GO:0051222 | positive regulation of protein transport | 0.027743861225859 |
GO:0019932 | second-messenger-mediated signaling | 0.027743861225859 |
GO:0051239 | regulation of multicellular organismal process | 0.0285894817718104 |
GO:0045840 | positive regulation of mitosis | 0.0285894817718104 |
GO:0006954 | inflammatory response | 0.028644406585695 |
GO:0015813 | L-glutamate transport | 0.028644406585695 |
GO:0015800 | acidic amino acid transport | 0.028644406585695 |
GO:0005102 | receptor binding | 0.030947997828804 |
GO:0050804 | regulation of synaptic transmission | 0.033559563047681 |
GO:0009612 | response to mechanical stimulus | 0.0340307536623605 |
GO:0001772 | immunological synapse | 0.0340307536623605 |
GO:0051969 | regulation of transmission of nerve impulse | 0.0352261380904179 |
GO:0044459 | plasma membrane part | 0.0354480104691158 |
GO:0016020 | membrane | 0.0372626362680686 |
GO:0005886 | plasma membrane | 0.0372626362680686 |
GO:0044425 | membrane part | 0.0422303467262425 |
GO:0045787 | positive regulation of progression through cell cycle | 0.0422303467262425 |
GO:0031644 | regulation of neurological process | 0.0422911808133526 |
GO:0043523 | regulation of neuron apoptosis | 0.0422911808133526 |
GO:0009611 | response to wounding | 0.0439685993139882 |
GO:0002274 | myeloid leukocyte activation | 0.0439685993139882 |
GO:0051223 | regulation of protein transport | 0.0447607868065524 |
GO:0007585 | respiratory gaseous exchange | 0.0453502471319412 |
GO:0051402 | neuron apoptosis | 0.0453502471319412 |
GO:0015758 | glucose transport | 0.0453502471319412 |
GO:0051051 | negative regulation of transport | 0.0453502471319412 |
GO:0008645 | hexose transport | 0.0453502471319412 |
GO:0015749 | monosaccharide transport | 0.0453502471319412 |
GO:0003993 | acid phosphatase activity | 0.0453502471319412 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
leukocyte | 1.57e-22 | 140 |
nongranular leukocyte | 2.07e-19 | 119 |
hematopoietic cell | 2.22e-19 | 182 |
hematopoietic lineage restricted progenitor cell | 6.67e-19 | 124 |
hematopoietic stem cell | 1.54e-18 | 172 |
angioblastic mesenchymal cell | 1.54e-18 | 172 |
hematopoietic oligopotent progenitor cell | 1.95e-17 | 165 |
hematopoietic multipotent progenitor cell | 1.95e-17 | 165 |
lymphocyte | 5.44e-17 | 53 |
common lymphoid progenitor | 5.44e-17 | 53 |
lymphoid lineage restricted progenitor cell | 1.20e-16 | 52 |
T cell | 2.21e-15 | 25 |
pro-T cell | 2.21e-15 | 25 |
mature alpha-beta T cell | 1.86e-11 | 18 |
alpha-beta T cell | 1.86e-11 | 18 |
immature T cell | 1.86e-11 | 18 |
mature T cell | 1.86e-11 | 18 |
immature alpha-beta T cell | 1.86e-11 | 18 |
CD8-positive, alpha-beta T cell | 9.45e-08 | 11 |
Ontology term | p-value | n |
---|---|---|
hemolymphoid system | 1.55e-13 | 112 |
hematopoietic system | 5.11e-13 | 102 |
blood island | 5.11e-13 | 102 |
blood | 1.60e-08 | 15 |
haemolymphatic fluid | 1.60e-08 | 15 |
organism substance | 1.60e-08 | 15 |
adult organism | 3.04e-07 | 115 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
No analysis results for this cluster
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.