CL:0000875: Difference between revisions
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|id=CL:0000875 | |id=CL:0000875 | ||
|name=non-classical monocyte | |name=non-classical monocyte | ||
|namespace=efo | |namespace=cell;;efo | ||
|def="Subset of monocytes characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168] | |def="Subset of monocytes characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168] | ||
|xref= | |xref= | ||
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|obo_creation_date= | |obo_creation_date= | ||
|subset= | |subset= | ||
|derives_from= | |derives_from= | ||
|develops_from= | |develops_from= | ||
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|located_in= | |located_in= | ||
|part_of= | |part_of= | ||
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo | |property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl | ||
|is_obsolete= | |is_obsolete= | ||
|preceded_by= | |preceded_by= | ||
}} | }} |
Latest revision as of 17:26, 26 June 2012
Name: | non-classical monocyte |
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Namespace: | cell;;efo |
Definition: | "Subset of monocytes characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, but increased co-stimulatory activity. May also play a role in tissue repair." [GO_REF:0000031, PMID:16322748, PMID:18303997, PMID:20628149, PMID:20870168] |
Synonyms: |
"patrolling monocyte" EXACT [] "resident monocyte" EXACT [] |
Comments: | Markers: CCR2-CX3CCR1+ (human, mouse, rat); human: CD16+, CCR5+, CD32/FcgRII-high, MHCII+, CD86+; mouse: CD62L-Ly6C-. |
Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | CL:0000576(monocyte) |
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Children
is a: | CL:0002396 (CD14-low, CD16-positive monocyte) |
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Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.
Human (Homo sapiens)
- 11790-124B8 (CD14-CD16+ Monocytes, donor1)
- 11800-124C9 (CD14-CD16+ Monocytes, donor2)
- 11911-125G3 (CD14-CD16+ Monocytes, donor3)
Mouse (Mus musculus)
- 11790-124B8 (CD14-CD16+ Monocytes, donor1)
- 11800-124C9 (CD14-CD16+ Monocytes, donor2)
- 11911-125G3 (CD14-CD16+ Monocytes, donor3)
Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000875 (non-classical monocyte), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data