Personal tools

Coexpression cluster:C230: Difference between revisions

From FANTOM5_SSTAR

Jump to: navigation, search
No edit summary
No edit summary
Line 1: Line 1:
{{Coexpression_clusters
{{Coexpression_clusters
|coexpression_dpi_cluster_scores_median=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0534545700183436,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0425916600387234,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0390744040629657,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0593771573651105,0,0,0,0,0,0,0,0,0,0,0,1.06296322055397,0,0,0,0,0,0,0,0,0.078198198554358,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0861409897892114,0,0,0.0902054036215435,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0368115019473605,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0978631351411755,0,0,0,0,0,0,0,0,0,0,0,0.0699368280688007,0,0,0,0,0.0402022792589852,0,0.0884836478019413,0,0,0.0266602233572113,0,0,0.0840229578243582,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.106966425460878,0.647129201513683,0,0,0,0,0.0547535628453514,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0256128589246175,0,0.0329432353726146,0.0222033657448865,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.084066558699748,0.118730395337086,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0261639379934246,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0608566712043477,0,0,0,0,0,0,0,0,0,0,0,0.29938140626407,0,0,0,0,0,0,0,0,0,0.0285589446518912,0,0,0,0.0633281735501667,0,0,0,0,0,0.0580284054719272,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0424427259395948,0,0,0,0,0,0,0,0,0.0322859259446875,0,0,0.0952210875623146,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0612855891386548,0,0,0,0,0,0,0,0,0.0267975841371139,0,0,0,0,0.0582150559773052,0,0,0,0,0,0,0.094988929438441,0,0,0.20515599882086,0
|full_id=C230_aorta_normal_heart_penis_osteosarcoma_basal_lung
|full_id=C230_aorta_normal_heart_penis_osteosarcoma_basal_lung
|gostat_on_coexpression_clusters=GO:0022610!biological adhesion!0.00609452779185376!8516;255743;54751;26032$GO:0007155!cell adhesion!0.00609452779185376!8516;255743;54751;26032$GO:0000902!cell morphogenesis!0.00933294408204043!8516;4856;54751$GO:0032989!cellular structure morphogenesis!0.00933294408204043!8516;4856;54751$GO:0030511!positive regulation of transforming growth factor beta receptor signaling pathway!0.0436562672371586!8516$GO:0032501!multicellular organismal process!0.0436562672371586!7871;8516;255743;51561;7068$GO:0005515!protein binding!0.0455961126751561!7871;8516;255743;4856;54751;51561;7068$GO:0009653!anatomical structure morphogenesis!0.0455961126751561!8516;4856;54751$GO:0004887!thyroid hormone receptor activity!0.0493564118487119!7068$GO:0007613!memory!0.0493564118487119!8516$GO:0005790!smooth endoplasmic reticulum!0.0493564118487119!7871
|gostat_on_coexpression_clusters=GO:0022610!biological adhesion!0.00609452779185376!8516;255743;54751;26032$GO:0007155!cell adhesion!0.00609452779185376!8516;255743;54751;26032$GO:0000902!cell morphogenesis!0.00933294408204043!8516;4856;54751$GO:0032989!cellular structure morphogenesis!0.00933294408204043!8516;4856;54751$GO:0030511!positive regulation of transforming growth factor beta receptor signaling pathway!0.0436562672371586!8516$GO:0032501!multicellular organismal process!0.0436562672371586!7871;8516;255743;51561;7068$GO:0005515!protein binding!0.0455961126751561!7871;8516;255743;4856;54751;51561;7068$GO:0009653!anatomical structure morphogenesis!0.0455961126751561!8516;4856;54751$GO:0004887!thyroid hormone receptor activity!0.0493564118487119!7068$GO:0007613!memory!0.0493564118487119!8516$GO:0005790!smooth endoplasmic reticulum!0.0493564118487119!7871

Revision as of 15:01, 12 September 2012


Full id: C230_aorta_normal_heart_penis_osteosarcoma_basal_lung



Phase1 CAGE Peaks

Hg19::chr10:15646574..15646578,-p11@ITGA8
Hg19::chr10:15760797..15760808,-p@chr10:15760797..15760808
-
Hg19::chr10:15760828..15760842,-p@chr10:15760828..15760842
-
Hg19::chr10:15761845..15761856,-p4@ITGA8
Hg19::chr10:15761884..15761936,-p1@ITGA8
Hg19::chr10:15761954..15761965,-p7@ITGA8
Hg19::chr10:15761966..15761979,-p2@ITGA8
Hg19::chr10:15762207..15762225,-p8@ITGA8
Hg19::chr10:15762227..15762257,-p3@ITGA8
Hg19::chr10:15762274..15762283,-p12@ITGA8
Hg19::chr10:15762312..15762340,-p6@ITGA8
Hg19::chr10:15762346..15762358,-p9@ITGA8
Hg19::chr12:19928351..19928358,+p2@ENST00000535764
Hg19::chr12:19928380..19928401,+p1@ENST00000535764
Hg19::chr13:39952800..39952810,-p@chr13:39952800..39952810
-
Hg19::chr14:92307575..92307589,-p@chr14:92307575..92307589
-
Hg19::chr14:92307596..92307610,-p@chr14:92307596..92307610
-
Hg19::chr14:92307628..92307643,-p@chr14:92307628..92307643
-
Hg19::chr16:2173505..2173521,-p1@AF088750
Hg19::chr16:73127519..73127528,-p@chr16:73127519..73127528
-
Hg19::chr16:73127560..73127571,-p@chr16:73127560..73127571
-
Hg19::chr17:12570155..12570163,+p@chr17:12570155..12570163
+
Hg19::chr1:16084107..16084112,+p19@FBLIM1
Hg19::chr1:163117077..163117096,-p@chr1:163117077..163117096
-
Hg19::chr1:48224242..48224244,+p@chr1:48224242..48224244
+
Hg19::chr22:25466244..25466263,+p8@KIAA1671
Hg19::chr22:25466273..25466284,+p7@KIAA1671
Hg19::chr22:25466305..25466317,+p6@KIAA1671
Hg19::chr2:107467431..107467465,-p@chr2:107467431..107467465
-
Hg19::chr2:18116344..18116353,+p@chr2:18116344..18116353
+
Hg19::chr2:285923..285935,+p1@ENST00000450709
Hg19::chr2:28958958..28958989,-p1@ENST00000444501
Hg19::chr2:28959059..28959099,-p1@ENST00000452212
Hg19::chr2:33285212..33285215,+p@chr2:33285212..33285215
+
Hg19::chr2:33285233..33285259,+p@chr2:33285233..33285259
+
Hg19::chr2:33285264..33285274,+p@chr2:33285264..33285274
+
Hg19::chr3:24231794..24231799,-p38@THRB
Hg19::chr3:29966392..29966406,+p22@RBMS3
Hg19::chr3:33260352..33260365,-p3@SUSD5
Hg19::chr3:33260373..33260422,-p2@SUSD5
Hg19::chr3:33260478..33260490,-p8@SUSD5
Hg19::chr3:33260765..33260770,-p7@SUSD5
Hg19::chr3:57881966..57881977,+p13@SLMAP
Hg19::chr3:57882024..57882045,+p10@SLMAP
Hg19::chr3:57882061..57882085,+p4@SLMAP
Hg19::chr4:106833328..106833353,+p7@NPNT
Hg19::chr4:119860470..119860487,+p@chr4:119860470..119860487
+
Hg19::chr4:15429533..15429568,-p1@ENST00000502344
Hg19::chr4:174846835..174846846,+p@chr4:174846835..174846846
+
Hg19::chr5:122448503..122448506,+p@chr5:122448503..122448506
+
Hg19::chr5:59792105..59792117,-p@chr5:59792105..59792117
-
Hg19::chr6:84743412..84743431,+p2@MRAP2
Hg19::chr6:84743436..84743496,+p1@MRAP2
Hg19::chr7:40549076..40549087,+p@chr7:40549076..40549087
+
Hg19::chr7:40549088..40549102,+p@chr7:40549088..40549102
+
Hg19::chr7:73462921..73462932,+p@chr7:73462921..73462932
+
Hg19::chr7:73468280..73468302,-p@chr7:73468280..73468302
-
Hg19::chr8:120428678..120428695,+p1@NOV
Hg19::chr8:120430391..120430409,+p@chr8:120430391..120430409
+
Hg19::chr8:120435183..120435195,-p1@CU677182
Hg19::chr8:97398865..97398877,-p1@ENST00000523862


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0022610biological adhesion0.00609452779185376
GO:0007155cell adhesion0.00609452779185376
GO:0000902cell morphogenesis0.00933294408204043
GO:0032989cellular structure morphogenesis0.00933294408204043
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathway0.0436562672371586
GO:0032501multicellular organismal process0.0436562672371586
GO:0005515protein binding0.0455961126751561
GO:0009653anatomical structure morphogenesis0.0455961126751561
GO:0004887thyroid hormone receptor activity0.0493564118487119
GO:0007613memory0.0493564118487119
GO:0005790smooth endoplasmic reticulum0.0493564118487119



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
non-terminally differentiated cell3.39e-07180
Uber Anatomy
Ontology termp-valuen
adult organism1.70e-39115
regional part of nervous system1.72e-2294
nervous system1.72e-2294
central nervous system3.25e-2282
neural tube3.55e-1957
neural rod3.55e-1957
future spinal cord3.55e-1957
neural keel3.55e-1957
brain1.09e-1869
future brain1.09e-1869
regional part of brain5.76e-1859
ectoderm-derived structure5.99e-18169
ectoderm1.09e-16173
presumptive ectoderm1.09e-16173
head3.78e-16123
anterior region of body6.03e-16129
craniocervical region6.03e-16129
neural plate2.22e-1586
presumptive neural plate2.22e-1586
anterior neural tube4.16e-1442
regional part of forebrain9.51e-1441
forebrain9.51e-1441
future forebrain9.51e-1441
neurectoderm1.10e-1390
multi-cellular organism9.75e-13659
anatomical cluster2.76e-11286
telencephalon2.80e-1134
gray matter4.88e-1134
brain grey matter4.88e-1134
cerebral hemisphere7.82e-1132
regional part of telencephalon8.39e-1133
anatomical system1.06e-10625
anatomical group2.12e-10626
pre-chordal neural plate2.56e-1061
regional part of cerebral cortex3.93e-1022
organism subdivision7.69e-10365
neocortex1.86e-0920
organ2.47e-09511
cerebral cortex1.55e-0825
pallium1.55e-0825
embryo8.55e-08612
organ part1.24e-07219
anatomical conduit5.71e-07241
embryonic structure6.72e-07605
developing anatomical structure6.72e-07605


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
RAD21#5885122.037055848286490.01280435981619930.0460700222153181



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

Retrieved from "http://f5-webapp4.gsc.riken.jp/resource_browser/index.php?title=Coexpression_cluster:C230&oldid=2136974"